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The map label for this gene is frc [H]

Identifier: 154245194

GI number: 154245194

Start: 1434343

End: 1435572

Strand: Direct

Name: frc [H]

Synonym: Xaut_1246

Alternate gene names: 154245194

Gene position: 1434343-1435572 (Clockwise)

Preceding gene: 154245193

Following gene: 154245195

Centisome position: 27.02

GC content: 68.62

Gene sequence:

>1230_bases
ATGGGCAAGGCGCTCGAAGGCGTGCGCGTCCTGGACATGACGCACGTGCAGTCCGGCCCCTCCGCGACGCAACTTCTTGC
GTGGCTGGGGGCGGAGGTCATCAAGGTCGAGATGCCGCGGCGCGGGGATATCACCCGGACGCAGCTGCGCGACAAGTCCA
ATGTGGACAGCCTTTACTTCACGATGCTGAACGCCAACAAGCAGAGCGTCACCATCAACATCAAGACGCCGCAGGGCCAG
GAAGCCATGGGGCGCCTGATCGACGCCTGCGACGTGCTGGTCGAGAATTTCGGCCCCGGCGTGCTGGACCGCCAGGGCTT
CGGTTACGAGGCCGTCCGCGCCCGCAACCCGCGCCTCATCTATGCCTCCATCCGCGGCTTCGCGGAGGGCGCCGGCGTGG
ACGCCAAGGCTTATGAGACCATCGCCCAGGCCATGGGCGGCGCCATGAGCACCACCGGCTGGCGGTCGGGCCCGCCCACC
GCCTCCAGCGCTCAGATCGGCGACACCGGCACCGGCATCCATTGCGTCACCGGTATCCTCGCGGCGCTCTACCAGCGCAC
CGTCACCGGCGAGGGTCAGAAGGTGGACGTGGCCATGCAGGACTGCGTGGTGAACCTTCTGCGGGTGAAGCTGCGCGACC
AGCAGCGCCTCGAAGCCGGGCCGCTCACCGAATATCCCGGCGCCCCGGAAGGGGACTGCGTGCCGCGGGCCGGCAACTGC
TCGGGCGGCGGCCAGCCCGGCGCGGCCCTGCGCTGCGCGCCGGGGGGCGAGAACGATTACTGCTACGTCATCATCCAGCC
CCAGGGCTGGGCGCCGCTGATGCGGCTGGTGGGCCGCAAGGACCTCATCGACGATCCCAAGTTCGCCTCCCACGAGGCCC
GGGCGCAGCGGCTGGAGCAGTGCTTCGAAATCATCGAGCGCTGGACCGCCAAGCGCACCAAGTTCGAGGTCATGGCGCAG
CTTAAGGCCATCGACGTTCCCTGCGGCCCGGTGCTGTCCACCAAGGACATCCTGGAGGACCGCGCGCTCTATGACCGGGG
CTTCCTGGTGGAGGTGCCGCATCCCGAGCGCGGCACCTACGTCACCGTGGGATCCCCCATCCATTTGTCCGCAAGCCACG
TTCCCGTCGAGCGCGCGCCGCTCCTCGGCGAGCATACGGACGAGGTGCTGGCCACCCTTGGCTACACCCATGAAGAGATC
GCCGGCATGCGTGCCGCCGGTGCAGTCTGA

Upstream 100 bases:

>100_bases
AGCGAGTGGCGACCCGGCGAAGCCGGTGACCCAGCGAACGGCAAGCCGGCGCAGACCGGCGGCTCCGCAAATCAGGGCAG
GGAAATCCGGGAGTGGAGGC

Downstream 100 bases:

>100_bases
CGGGAGAAAAACGCCCGTTTGAACATCCGCCGCTCCATGAGGGACAAAAAGAGGGTGGAGCGGTTAACAACATCAAAAAA
TATAAAAGTCTCAAGGGGTA

Product: formyl-coenzyme A transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MGKALEGVRVLDMTHVQSGPSATQLLAWLGAEVIKVEMPRRGDITRTQLRDKSNVDSLYFTMLNANKQSVTINIKTPQGQ
EAMGRLIDACDVLVENFGPGVLDRQGFGYEAVRARNPRLIYASIRGFAEGAGVDAKAYETIAQAMGGAMSTTGWRSGPPT
ASSAQIGDTGTGIHCVTGILAALYQRTVTGEGQKVDVAMQDCVVNLLRVKLRDQQRLEAGPLTEYPGAPEGDCVPRAGNC
SGGGQPGAALRCAPGGENDYCYVIIQPQGWAPLMRLVGRKDLIDDPKFASHEARAQRLEQCFEIIERWTAKRTKFEVMAQ
LKAIDVPCGPVLSTKDILEDRALYDRGFLVEVPHPERGTYVTVGSPIHLSASHVPVERAPLLGEHTDEVLATLGYTHEEI
AGMRAAGAV

Sequences:

>Translated_409_residues
MGKALEGVRVLDMTHVQSGPSATQLLAWLGAEVIKVEMPRRGDITRTQLRDKSNVDSLYFTMLNANKQSVTINIKTPQGQ
EAMGRLIDACDVLVENFGPGVLDRQGFGYEAVRARNPRLIYASIRGFAEGAGVDAKAYETIAQAMGGAMSTTGWRSGPPT
ASSAQIGDTGTGIHCVTGILAALYQRTVTGEGQKVDVAMQDCVVNLLRVKLRDQQRLEAGPLTEYPGAPEGDCVPRAGNC
SGGGQPGAALRCAPGGENDYCYVIIQPQGWAPLMRLVGRKDLIDDPKFASHEARAQRLEQCFEIIERWTAKRTKFEVMAQ
LKAIDVPCGPVLSTKDILEDRALYDRGFLVEVPHPERGTYVTVGSPIHLSASHVPVERAPLLGEHTDEVLATLGYTHEEI
AGMRAAGAV
>Mature_408_residues
GKALEGVRVLDMTHVQSGPSATQLLAWLGAEVIKVEMPRRGDITRTQLRDKSNVDSLYFTMLNANKQSVTINIKTPQGQE
AMGRLIDACDVLVENFGPGVLDRQGFGYEAVRARNPRLIYASIRGFAEGAGVDAKAYETIAQAMGGAMSTTGWRSGPPTA
SSAQIGDTGTGIHCVTGILAALYQRTVTGEGQKVDVAMQDCVVNLLRVKLRDQQRLEAGPLTEYPGAPEGDCVPRAGNCS
GGGQPGAALRCAPGGENDYCYVIIQPQGWAPLMRLVGRKDLIDDPKFASHEARAQRLEQCFEIIERWTAKRTKFEVMAQL
KAIDVPCGPVLSTKDILEDRALYDRGFLVEVPHPERGTYVTVGSPIHLSASHVPVERAPLLGEHTDEVLATLGYTHEEIA
GMRAAGAV

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=413, Percent_Identity=31.2348668280872, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI300863124, Length=440, Percent_Identity=29.7727272727273, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI42794625, Length=413, Percent_Identity=27.6029055690073, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI266456254, Length=418, Percent_Identity=27.2727272727273, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI13376042, Length=440, Percent_Identity=26.3636363636364, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI300863126, Length=152, Percent_Identity=44.7368421052632, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI266458393, Length=316, Percent_Identity=28.1645569620253, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI266458397, Length=215, Percent_Identity=31.1627906976744, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI266458395, Length=127, Percent_Identity=33.0708661417323, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI42822893, Length=127, Percent_Identity=33.0708661417323, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1788717, Length=417, Percent_Identity=51.0791366906475, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI87082093, Length=389, Percent_Identity=33.4190231362468, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1786222, Length=345, Percent_Identity=24.9275362318841, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648431, Length=414, Percent_Identity=34.5410628019324, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24585488, Length=197, Percent_Identity=32.48730964467, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 44110; Mature: 43979

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKALEGVRVLDMTHVQSGPSATQLLAWLGAEVIKVEMPRRGDITRTQLRDKSNVDSLYF
CCCCCCCEEEEEEHHCCCCCCHHHHHHHHCCEEEEEECCCCCCCHHHHHCCCCCCCEEEE
TMLNANKQSVTINIKTPQGQEAMGRLIDACDVLVENFGPGVLDRQGFGYEAVRARNPRLI
EEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEEE
YASIRGFAEGAGVDAKAYETIAQAMGGAMSTTGWRSGPPTASSAQIGDTGTGIHCVTGIL
EEECCCHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AALYQRTVTGEGQKVDVAMQDCVVNLLRVKLRDQQRLEAGPLTEYPGAPEGDCVPRAGNC
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SGGGQPGAALRCAPGGENDYCYVIIQPQGWAPLMRLVGRKDLIDDPKFASHEARAQRLEQ
CCCCCCCCEEEECCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
CFEIIERWTAKRTKFEVMAQLKAIDVPCGPVLSTKDILEDRALYDRGFLVEVPHPERGTY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCE
VTVGSPIHLSASHVPVERAPLLGEHTDEVLATLGYTHEEIAGMRAAGAV
EEECCCEEECCCCCCHHCCCCCCCCHHHHHHHHCCCHHHHHCCHHCCCC
>Mature Secondary Structure 
GKALEGVRVLDMTHVQSGPSATQLLAWLGAEVIKVEMPRRGDITRTQLRDKSNVDSLYF
CCCCCCEEEEEEHHCCCCCCHHHHHHHHCCEEEEEECCCCCCCHHHHHCCCCCCCEEEE
TMLNANKQSVTINIKTPQGQEAMGRLIDACDVLVENFGPGVLDRQGFGYEAVRARNPRLI
EEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEEE
YASIRGFAEGAGVDAKAYETIAQAMGGAMSTTGWRSGPPTASSAQIGDTGTGIHCVTGIL
EEECCCHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AALYQRTVTGEGQKVDVAMQDCVVNLLRVKLRDQQRLEAGPLTEYPGAPEGDCVPRAGNC
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SGGGQPGAALRCAPGGENDYCYVIIQPQGWAPLMRLVGRKDLIDDPKFASHEARAQRLEQ
CCCCCCCCEEEECCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
CFEIIERWTAKRTKFEVMAQLKAIDVPCGPVLSTKDILEDRALYDRGFLVEVPHPERGTY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCE
VTVGSPIHLSASHVPVERAPLLGEHTDEVLATLGYTHEEIAGMRAAGAV
EEECCCEEECCCCCCHHCCCCCCCCHHHHHHHHCCCHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]