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The map label for this gene is ttuB [H]

Identifier: 154244978

GI number: 154244978

Start: 1180775

End: 1182088

Strand: Reverse

Name: ttuB [H]

Synonym: Xaut_1028

Alternate gene names: 154244978

Gene position: 1182088-1180775 (Counterclockwise)

Preceding gene: 154244981

Following gene: 154244977

Centisome position: 22.27

GC content: 63.7

Gene sequence:

>1314_bases
ATGAGCACCCAAACCGCGCCCCTCGCGGCGCACGTCGCCGTGGAACCCGACACGCAGAAGGCCGCCTACGCCAAGGTGTT
CTGGCGCATCGTCCCGTTCCTGATGCTGTGCTACGTGGTGGCCTACCTCGACCGGGTGAACGTGGGCTTCGCCAAGCTCC
AGATGTCGCAGGACCTGAACTTCAGCGAGACCGTCTACGGCCTCGGCGCCGGCATCTTCTTCCTCGGCTATTTCCTGTTC
GAGGTGCCAAGCAACGTCATTCTCCACAAGGTCGGCGCGCGCATCTGGATCGCCCGTATCATGGTGACCTGGGGTCTCAT
CTCCGGCGCCTTCATGTTCGTCTCCAGCGCGCCCATGTTCTATGCCCTGCGCTTCCTGCTCGGGGTCGCCGAAGCCGGCT
TCTATCCCGGCATCATCCTGTACCTGACCTATTGGTATCCCTCGCACCGCCGCGCCAAGATCATCGCCATCTTCATGTCG
GCGATCCCGATTTCCGGAATCTTCGGCAATCCTCTGTCGGGCTGGATCATGGACAGCTTCCACGGCACCTCGGGGCTGGC
CGGCTGGCAGTGGATGTTCCTCATCGAGGCCATTCCGGCCATCGCCATCGGCATCGTCATCTATTTCTATCTCGACAATG
GCATTCGCGACGCCAAGTGGCTGAGCGCCGAGCACAAGGCCGTGCTGGAATATGAAATCGCCCAGGAAGAAAAGACCAAG
GAAGGCCACCACTCGGTTGCCGGCGTGTTCGCCGACAACCGGATCTGGCTCATGAGCTTCATCTACTTCTGCTTCGTCAT
GGGCCAGTATGCCCTGACCTTCTGGATGCCCACCCTGGTGAAGGCGACCGGCGTCGTCGGCAACTTCCACATCGGCCTCG
TCAGCGCCATTCCCTTCCTCTGCGCCGTCATCGCCATGAACCTGATCGGCCGCAGTTCGGACCGCCATCGCGAACGGCGC
TGGCATCTCGTCGTCCCGGCGCTGATGGGCGCGGTGGGCTTCACGGTGGCCGCCACCTCCACCAGCACCACGGTGGCCAT
CATCTTCCTGTCCATCGCCGCTGCCGGCGCCATCTCCTGCGCGCCGCTGTTCTGGTCCCTGCCCACCGCGTTCCTCGCCG
GCACGGGCGCCGCCGCAGGCATCGCGCTGATCAATTCGGTGGGCAATCTCGCCGGATTCGTCAGCCCCTACCTCATCGGC
TTCCTGAAGGACCTCACCGGCTCCACCCAGGTGGGCATGTATGCCCTCGCGGCGATCCTGGTGGCCGGCGCCGCTGCGGT
GCTCACCACCTCGCCCAAGCTCGTCAACAAGTGA

Upstream 100 bases:

>100_bases
GCGCTGCCACTGTTTGCTATGTGCTGATGGCAGCGCTGCCATGCCCAGCACGCAGCCCGACACGACAGCCAACACAAACG
CCACCTCCAGGGAGGACCCG

Downstream 100 bases:

>100_bases
ACCCACAGCCTCCCGCGGCGCGATCCGCGGGAGGCCCCTCGTGCCGATGCCGTCGCAGCGCAGCTCCCTTTTCGAGGATC
AGGTCATGACAGAACAGTTC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSTQTAPLAAHVAVEPDTQKAAYAKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLNFSETVYGLGAGIFFLGYFLF
EVPSNVILHKVGARIWIARIMVTWGLISGAFMFVSSAPMFYALRFLLGVAEAGFYPGIILYLTYWYPSHRRAKIIAIFMS
AIPISGIFGNPLSGWIMDSFHGTSGLAGWQWMFLIEAIPAIAIGIVIYFYLDNGIRDAKWLSAEHKAVLEYEIAQEEKTK
EGHHSVAGVFADNRIWLMSFIYFCFVMGQYALTFWMPTLVKATGVVGNFHIGLVSAIPFLCAVIAMNLIGRSSDRHRERR
WHLVVPALMGAVGFTVAATSTSTTVAIIFLSIAAAGAISCAPLFWSLPTAFLAGTGAAAGIALINSVGNLAGFVSPYLIG
FLKDLTGSTQVGMYALAAILVAGAAAVLTTSPKLVNK

Sequences:

>Translated_437_residues
MSTQTAPLAAHVAVEPDTQKAAYAKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLNFSETVYGLGAGIFFLGYFLF
EVPSNVILHKVGARIWIARIMVTWGLISGAFMFVSSAPMFYALRFLLGVAEAGFYPGIILYLTYWYPSHRRAKIIAIFMS
AIPISGIFGNPLSGWIMDSFHGTSGLAGWQWMFLIEAIPAIAIGIVIYFYLDNGIRDAKWLSAEHKAVLEYEIAQEEKTK
EGHHSVAGVFADNRIWLMSFIYFCFVMGQYALTFWMPTLVKATGVVGNFHIGLVSAIPFLCAVIAMNLIGRSSDRHRERR
WHLVVPALMGAVGFTVAATSTSTTVAIIFLSIAAAGAISCAPLFWSLPTAFLAGTGAAAGIALINSVGNLAGFVSPYLIG
FLKDLTGSTQVGMYALAAILVAGAAAVLTTSPKLVNK
>Mature_436_residues
STQTAPLAAHVAVEPDTQKAAYAKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLNFSETVYGLGAGIFFLGYFLFE
VPSNVILHKVGARIWIARIMVTWGLISGAFMFVSSAPMFYALRFLLGVAEAGFYPGIILYLTYWYPSHRRAKIIAIFMSA
IPISGIFGNPLSGWIMDSFHGTSGLAGWQWMFLIEAIPAIAIGIVIYFYLDNGIRDAKWLSAEHKAVLEYEIAQEEKTKE
GHHSVAGVFADNRIWLMSFIYFCFVMGQYALTFWMPTLVKATGVVGNFHIGLVSAIPFLCAVIAMNLIGRSSDRHRERRW
HLVVPALMGAVGFTVAATSTSTTVAIIFLSIAAAGAISCAPLFWSLPTAFLAGTGAAAGIALINSVGNLAGFVSPYLIGF
LKDLTGSTQVGMYALAAILVAGAAAVLTTSPKLVNK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=402, Percent_Identity=37.0646766169154, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1789152, Length=439, Percent_Identity=26.4236902050114, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789515, Length=414, Percent_Identity=25.1207729468599, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI2367379, Length=456, Percent_Identity=22.8070175438596, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082320, Length=433, Percent_Identity=21.7090069284065, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319876, Length=322, Percent_Identity=25.4658385093168, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322025, Length=201, Percent_Identity=28.3582089552239, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321698, Length=390, Percent_Identity=24.1025641025641, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324410, Length=158, Percent_Identity=26.5822784810127, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319250, Length=177, Percent_Identity=25.4237288135593, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=279, Percent_Identity=20.7885304659498, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321502, Length=200, Percent_Identity=27, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584153, Length=364, Percent_Identity=22.5274725274725, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47469; Mature: 47338

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCHHHHHCCCCHHCCC
>Mature Secondary Structure 
STQTAPLAAHVAVEPDTQKAAYAKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLN
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEHHCCCC
FSETVYGLGAGIFFLGYFLFEVPSNVILHKVGARIWIARIMVTWGLISGAFMFVSSAPMF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
YALRFLLGVAEAGFYPGIILYLTYWYPSHRRAKIIAIFMSAIPISGIFGNPLSGWIMDSF
HHHHHHHHHHHCCCCCCCEEEEEHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCC
HGTSGLAGWQWMFLIEAIPAIAIGIVIYFYLDNGIRDAKWLSAEHKAVLEYEIAQEEKTK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCC
EGHHSVAGVFADNRIWLMSFIYFCFVMGQYALTFWMPTLVKATGVVGNFHIGLVSAIPFL
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
CAVIAMNLIGRSSDRHRERRWHLVVPALMGAVGFTVAATSTSTTVAIIFLSIAAAGAISC
HHHHHHHHHCCCCCHHHHHHHHEEHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCHHHH
APLFWSLPTAFLAGTGAAAGIALINSVGNLAGFVSPYLIGFLKDLTGSTQVGMYALAAIL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VAGAAAVLTTSPKLVNK
HHCHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]