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The map label for this gene is azoR

Identifier: 154244923

GI number: 154244923

Start: 1090477

End: 1091103

Strand: Direct

Name: azoR

Synonym: Xaut_0973

Alternate gene names: 154244923

Gene position: 1090477-1091103 (Clockwise)

Preceding gene: 154244921

Following gene: 154244924

Centisome position: 20.54

GC content: 67.62

Gene sequence:

>627_bases
ATGAAGACATTGCTTCGCATCGATTCCAGCGCACGTATCGAGGGCTCGCGGTCGCGGCGGCTCGGCGATGCGCTGGAGGC
ACGCTGGCGCGCCGGCAGCCCCGACGGCGCGGTGGTCCGGCGGGACCTCGCGGCCGATCCCGTTCCGCACATCGAGGCCA
CCACCATCGCCGGCTTCTTCACTCCGGCGGACCAGGTCACCGATGCGATGCGGGCCGCGACCGTGCTATCCGACCGGCTC
ATCGGCGAGGTGGAGGCGGCGGATGCCCTGCTCATCACCGCGCCAATGTATAATTTCGGCCTGCCCTCCACGTTGAAGGC
GTGGATCGACCATGTGGTGCGCATCCACCGCACCGTCGCCTATGACGGCACCACCTTCCGGGGCCTCGTAACCGGCAAGG
CGGCCTATGTGGCGCTCGCCTATGGCGCGGGGAGCTACGAGCCGGGCGGGACGCTGGCCCCCTTCGACTATGCCAAGCCC
TATCTTACCCACGTGCTCGGTTTCATTGGCTTTCGCGACATCGAGGTGGTGGGCGTGGAAGGCACCAGTGGCGAGGAAGG
CGCGGCTGCGGCTGCGCTCGATGCCGCACTGAAAGCCATCGAAAACCTGCCGTCTCTCGCCGCCTGA

Upstream 100 bases:

>100_bases
TCCATTCGTGCAGCTTATGCACGAATGTACTGTCGCAGTCCCCATTTTTCCCCGCCGTGGGCGCGCGCCATCTTGCCTCC
GCTTTTGGAGGTATCTTGGC

Downstream 100 bases:

>100_bases
AATTTTCCGGCGAAAAATCGTCGGATGCGCGAATAAAACCGAATGCTCCGCGGTCTTGGCTGGTGTGGGTCCGCCCACGC
CAGCTGAAGCGGCCGCTCCC

Product: NAD(P)H dehydrogenase (quinone)

Products: 4'-phosphopantetheine; apoprotein

Alternate protein names: Azo-dye reductase; FMN-dependent NADH-azo compound oxidoreductase

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKTLLRIDSSARIEGSRSRRLGDALEARWRAGSPDGAVVRRDLAADPVPHIEATTIAGFFTPADQVTDAMRAATVLSDRL
IGEVEAADALLITAPMYNFGLPSTLKAWIDHVVRIHRTVAYDGTTFRGLVTGKAAYVALAYGAGSYEPGGTLAPFDYAKP
YLTHVLGFIGFRDIEVVGVEGTSGEEGAAAAALDAALKAIENLPSLAA

Sequences:

>Translated_208_residues
MKTLLRIDSSARIEGSRSRRLGDALEARWRAGSPDGAVVRRDLAADPVPHIEATTIAGFFTPADQVTDAMRAATVLSDRL
IGEVEAADALLITAPMYNFGLPSTLKAWIDHVVRIHRTVAYDGTTFRGLVTGKAAYVALAYGAGSYEPGGTLAPFDYAKP
YLTHVLGFIGFRDIEVVGVEGTSGEEGAAAAALDAALKAIENLPSLAA
>Mature_208_residues
MKTLLRIDSSARIEGSRSRRLGDALEARWRAGSPDGAVVRRDLAADPVPHIEATTIAGFFTPADQVTDAMRAATVLSDRL
IGEVEAADALLITAPMYNFGLPSTLKAWIDHVVRIHRTVAYDGTTFRGLVTGKAAYVALAYGAGSYEPGGTLAPFDYAKP
YLTHVLGFIGFRDIEVVGVEGTSGEEGAAAAALDAALKAIENLPSLAA

Specific function: Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity

COG id: COG1182

COG function: function code I; Acyl carrier protein phosphodiesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the azoreductase type 1 family

Homologues:

Organism=Escherichia coli, GI1787680, Length=197, Percent_Identity=38.5786802030457, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AZOR_XANP2 (A7IDY1)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001415881.1
- ProteinModelPortal:   A7IDY1
- SMR:   A7IDY1
- STRING:   A7IDY1
- GeneID:   5424275
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_0973
- eggNOG:   COG1182
- HOGENOM:   HBG565834
- OMA:   HRDPLPH
- ProtClustDB:   CLSK970894
- BioCyc:   XAUT78245:XAUT_0973-MONOMER
- HAMAP:   MF_01216
- InterPro:   IPR003680
- InterPro:   IPR023048

Pfam domain/function: PF02525 Flavodoxin_2

EC number: 3.1.4.14

Molecular weight: Translated: 21930; Mature: 21930

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLLRIDSSARIEGSRSRRLGDALEARWRAGSPDGAVVRRDLAADPVPHIEATTIAGFF
CCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHEEHHHCCCCCCCCCHHEEEEEC
TPADQVTDAMRAATVLSDRLIGEVEAADALLITAPMYNFGLPSTLKAWIDHVVRIHRTVA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCCHHHHHHHHHHHHHHHHHE
YDGTTFRGLVTGKAAYVALAYGAGSYEPGGTLAPFDYAKPYLTHVLGFIGFRDIEVVGVE
ECCCEEEEEEECCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEC
GTSGEEGAAAAALDAALKAIENLPSLAA
CCCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKTLLRIDSSARIEGSRSRRLGDALEARWRAGSPDGAVVRRDLAADPVPHIEATTIAGFF
CCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHEEHHHCCCCCCCCCHHEEEEEC
TPADQVTDAMRAATVLSDRLIGEVEAADALLITAPMYNFGLPSTLKAWIDHVVRIHRTVA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCCHHHHHHHHHHHHHHHHHE
YDGTTFRGLVTGKAAYVALAYGAGSYEPGGTLAPFDYAKPYLTHVLGFIGFRDIEVVGVE
ECCCEEEEEEECCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEC
GTSGEEGAAAAALDAALKAIENLPSLAA
CCCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: [acyl-carrier protein]; H2O

Specific reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein

General reaction: Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA