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The map label for this gene is mhpB

Identifier: 154244882

GI number: 154244882

Start: 1052252

End: 1053193

Strand: Direct

Name: mhpB

Synonym: Xaut_0932

Alternate gene names: 154244882

Gene position: 1052252-1053193 (Clockwise)

Preceding gene: 154244875

Following gene: 154244883

Centisome position: 19.82

GC content: 66.03

Gene sequence:

>942_bases
ATGACCATCAAGCTCAAGTGCCTTTCGCACACGCCTCTGCGTGGCCTGAACGATCCCGCGCCGGAGGTGATCGCCGAAGT
CGATGCGGTGCTGGCCCGCGCCCGCGCCGATGTGGAAGCATTCGACCCCGAGCTGATCGTGATTTTCGCGCCGGATCACT
ATAACGGCCTCTTCTACGATCTGATGCCGCCATTCGTTATTGCAACGGCGGCGAAGTCGGTCGGGGATTACATGACTTTG
CCGGGTCCGCTCTCGGTGGAGCGCGATCTGGCGCTCGAGCTGGCGCGCTTCATCCTCGATCACGACGTGGACATCTCCCT
GTCCCATCGCCTGCAAGTGGATCACGGCTGCACCCAGACCCTGGAAGAGCTGACCGGCAGCCTCACGCGCTATCCGGTGA
TCCCCATCATCATCAATTCGGTGGCGCCCCCCTTTGCGCCCTATCGGCGGATCCGCCGCCTCGGCGAAGTGGTCGGACAA
TTCATCGCCACCCTCGACAAGCGGGTGCTGGTGCTGGGCACCGGCGGGCTGTCCCACGAGCCTCCGGTGCCGCTTCTGGA
GGGCGCGCCCGAAGCCATCGGCGAATTCCTGATCTGCGGGCGCAATCCCACCCCCGAAGCGCGCGCCGCCCGGCAGGAGC
GCACCATCGCCGCCGGCAAGATCTACGGCACCGAGCTGTCCGCGCAGACCCCTCTCAATGCCGAGTGGGATCAGGCCTTC
ATCGACCTTCTGCTGGATGCCCGGCTCGACGCCGTGGACGACTTCAGCATCGAGGAAATCTCGAAGGAAGCCGGCCGCTC
CACCCATGAGGTCCGCACCTGGGTGGCGGCGTTCGCGGCGCTTGCGGCGGCCCGGGGCGGCTACAGCGCGCACCGCGACT
ACTACCGCCCGATCAATGAATGGATCGCCGGCTACGGCGTCATGAGCGCCGAGCCACGCTGA

Upstream 100 bases:

>100_bases
CATAAGGTGATCCCGCTCAAAACGAAGAACGCGACCGGGAAGGGAGGAGCGGGCCAGGCATTGCCGTGGACCTGCAGCTT
CCACGGTCGAGGGAGCCATC

Downstream 100 bases:

>100_bases
CAGCGTGCATGCGAAGCCCAGCGAGGAACGCCAGGAGAATCAGGATGTTGGACAGATCAAGCTGCACGCCCACCGAGGCC
GAGATTGTCGCCCGCGCCGA

Product: 3-(2,3-dihydroxyphenyl)propionate dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTIKLKCLSHTPLRGLNDPAPEVIAEVDAVLARARADVEAFDPELIVIFAPDHYNGLFYDLMPPFVIATAAKSVGDYMTL
PGPLSVERDLALELARFILDHDVDISLSHRLQVDHGCTQTLEELTGSLTRYPVIPIIINSVAPPFAPYRRIRRLGEVVGQ
FIATLDKRVLVLGTGGLSHEPPVPLLEGAPEAIGEFLICGRNPTPEARAARQERTIAAGKIYGTELSAQTPLNAEWDQAF
IDLLLDARLDAVDDFSIEEISKEAGRSTHEVRTWVAAFAALAAARGGYSAHRDYYRPINEWIAGYGVMSAEPR

Sequences:

>Translated_313_residues
MTIKLKCLSHTPLRGLNDPAPEVIAEVDAVLARARADVEAFDPELIVIFAPDHYNGLFYDLMPPFVIATAAKSVGDYMTL
PGPLSVERDLALELARFILDHDVDISLSHRLQVDHGCTQTLEELTGSLTRYPVIPIIINSVAPPFAPYRRIRRLGEVVGQ
FIATLDKRVLVLGTGGLSHEPPVPLLEGAPEAIGEFLICGRNPTPEARAARQERTIAAGKIYGTELSAQTPLNAEWDQAF
IDLLLDARLDAVDDFSIEEISKEAGRSTHEVRTWVAAFAALAAARGGYSAHRDYYRPINEWIAGYGVMSAEPR
>Mature_312_residues
TIKLKCLSHTPLRGLNDPAPEVIAEVDAVLARARADVEAFDPELIVIFAPDHYNGLFYDLMPPFVIATAAKSVGDYMTLP
GPLSVERDLALELARFILDHDVDISLSHRLQVDHGCTQTLEELTGSLTRYPVIPIIINSVAPPFAPYRRIRRLGEVVGQF
IATLDKRVLVLGTGGLSHEPPVPLLEGAPEAIGEFLICGRNPTPEARAARQERTIAAGKIYGTELSAQTPLNAEWDQAFI
DLLLDARLDAVDDFSIEEISKEAGRSTHEVRTWVAAFAALAAARGGYSAHRDYYRPINEWIAGYGVMSAEPR

Specific function: Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ligB/mhpB extradiol dioxygenase family

Homologues:

Organism=Escherichia coli, GI1786544, Length=311, Percent_Identity=47.588424437299, Blast_Score=293, Evalue=9e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MHPB_XANP2 (A7IDU0)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001415840.1
- ProteinModelPortal:   A7IDU0
- SMR:   A7IDU0
- STRING:   A7IDU0
- GeneID:   5424278
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_0932
- eggNOG:   NOG42398
- HOGENOM:   HBG565586
- OMA:   PLNPEWD
- ProtClustDB:   PRK13370
- BioCyc:   XAUT78245:XAUT_0932-MONOMER
- HAMAP:   MF_01653
- InterPro:   IPR004183

Pfam domain/function: PF02900 LigB; SSF53213 Xdiol_dOase_3B

EC number: =1.13.11.16

Molecular weight: Translated: 34305; Mature: 34173

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: ACT_SITE 115-115 ACT_SITE 179-179

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKLKCLSHTPLRGLNDPAPEVIAEVDAVLARARADVEAFDPELIVIFAPDHYNGLFYD
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCCCCCCEEHH
LMPPFVIATAAKSVGDYMTLPGPLSVERDLALELARFILDHDVDISLSHRLQVDHGCTQT
HHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEEECCEEECCCCHHHH
LEELTGSLTRYPVIPIIINSVAPPFAPYRRIRRLGEVVGQFIATLDKRVLVLGTGGLSHE
HHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
PPVPLLEGAPEAIGEFLICGRNPTPEARAARQERTIAAGKIYGTELSAQTPLNAEWDQAF
CCCCHHCCCHHHHHHEEEECCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCCCHHHHHH
IDLLLDARLDAVDDFSIEEISKEAGRSTHEVRTWVAAFAALAAARGGYSAHRDYYRPINE
HHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WIAGYGVMSAEPR
HHHCCCCCCCCCC
>Mature Secondary Structure 
TIKLKCLSHTPLRGLNDPAPEVIAEVDAVLARARADVEAFDPELIVIFAPDHYNGLFYD
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCCCCCCEEHH
LMPPFVIATAAKSVGDYMTLPGPLSVERDLALELARFILDHDVDISLSHRLQVDHGCTQT
HHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEEECCEEECCCCHHHH
LEELTGSLTRYPVIPIIINSVAPPFAPYRRIRRLGEVVGQFIATLDKRVLVLGTGGLSHE
HHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
PPVPLLEGAPEAIGEFLICGRNPTPEARAARQERTIAAGKIYGTELSAQTPLNAEWDQAF
CCCCHHCCCHHHHHHEEEECCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCCCHHHHHH
IDLLLDARLDAVDDFSIEEISKEAGRSTHEVRTWVAAFAALAAARGGYSAHRDYYRPINE
HHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WIAGYGVMSAEPR
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA