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The map label for this gene is etfA [H]

Identifier: 154244871

GI number: 154244871

Start: 1038354

End: 1039325

Strand: Direct

Name: etfA [H]

Synonym: Xaut_0921

Alternate gene names: 154244871

Gene position: 1038354-1039325 (Clockwise)

Preceding gene: 154244870

Following gene: 154244872

Centisome position: 19.56

GC content: 70.16

Gene sequence:

>972_bases
ATGTCCGGAATTCTCATTCTGGCCGAGCACAGGCGCGGCGTGCTGCGGGACGCCACGCTGGAGGCCATCGGCGCCGCCGG
CGAGCTGAAGGGCGCCCTCGGCGGCCCCGTCACCGTGCTGGTCATTGCCGCCGATCCTTCACCCTTCGTCGGCGCCGTCA
GCGTCGGCGCGGTGGACGAGGTGATCACCGTCGCCCGCCCCGATGCGGAGACCTTCGAGCCGCACGTCTATGAGGCGGTG
CTGAAGGCCGTCATCTCCGCGCGCGCGCCCTCCCTCGTGCTGATGCCGCACAGCGTGGACAGCTTTGCGCTCGCTCCCGC
CGTCGCGGTGGGCCTCGGCCTCGGCTTTGCCACCGACGTGTTCGGCCTTGCCGTCGAGGACGGCGAGGTGGTGGCGACGC
GGGCGGGCTACAACGAGAAGGTCTTCGTGGAGATCGACTTTCCCGGCCGGTCCGGCGTGCTTGTCACCCTGCGCGGCGGC
GCCTTCGCGCCAGCCACCGTGCCGGCGAGCCCGACCGTCTCGGCGCTGGATGCGGGCGAGGGCAAGCCGCGCAGCCGGCA
CCTGGAGTGGCGCGATCCGCCGGCCAGCGGCGGCATCGACATTCCCGGCTCGCCCTTCATCCTGTCCATCGGCCGCGGGG
TCGGGGACGAGGCCAACGTGGCCCAGTTCCTGGAGCTGGCCGAGGGGCTCGGTGCCACGCTCGGCTGCTCGCGGCCCATC
GCCGACAGCGGCTGGCTACCCAAGGCCCGGCAGGTGGGCCAGTCCGGCCAGCTGGCGGCCAAGTGCAACCTCTACATCGC
CATGGGCATCTCCGGCTCGGTGCAGCACCAGTGGGGCATGAAGCACGTGGAGAACATCGTCGCGATCAACAAGGATCCGG
AGGCCTCGATCTTCACCATCGCTCGCTACGGCATCGTCGGCGACATGCTTGAGATCGCCGAAGAACTGCGCAAGCAGCAG
GGTATCCAGTAA

Upstream 100 bases:

>100_bases
GCGTCTTCGTGCCCGAGCGGGGCCGGGGCGAGATCATCGAGGGCACGCCCGCGCAGCAGGCGGCCCGTCTTCTGGAAATC
ATCACGGAGGTGAAGGGCTG

Downstream 100 bases:

>100_bases
AGCGCAAGGACAGCGGCCGGGGCCATCGATCGCCAAGTCGATCCCGGCCGCAACAGTTTCACGAAACAAGCGGTCTCACC
AAACAAAAGCGTCCGGACGG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSGILILAEHRRGVLRDATLEAIGAAGELKGALGGPVTVLVIAADPSPFVGAVSVGAVDEVITVARPDAETFEPHVYEAV
LKAVISARAPSLVLMPHSVDSFALAPAVAVGLGLGFATDVFGLAVEDGEVVATRAGYNEKVFVEIDFPGRSGVLVTLRGG
AFAPATVPASPTVSALDAGEGKPRSRHLEWRDPPASGGIDIPGSPFILSIGRGVGDEANVAQFLELAEGLGATLGCSRPI
ADSGWLPKARQVGQSGQLAAKCNLYIAMGISGSVQHQWGMKHVENIVAINKDPEASIFTIARYGIVGDMLEIAEELRKQQ
GIQ

Sequences:

>Translated_323_residues
MSGILILAEHRRGVLRDATLEAIGAAGELKGALGGPVTVLVIAADPSPFVGAVSVGAVDEVITVARPDAETFEPHVYEAV
LKAVISARAPSLVLMPHSVDSFALAPAVAVGLGLGFATDVFGLAVEDGEVVATRAGYNEKVFVEIDFPGRSGVLVTLRGG
AFAPATVPASPTVSALDAGEGKPRSRHLEWRDPPASGGIDIPGSPFILSIGRGVGDEANVAQFLELAEGLGATLGCSRPI
ADSGWLPKARQVGQSGQLAAKCNLYIAMGISGSVQHQWGMKHVENIVAINKDPEASIFTIARYGIVGDMLEIAEELRKQQ
GIQ
>Mature_322_residues
SGILILAEHRRGVLRDATLEAIGAAGELKGALGGPVTVLVIAADPSPFVGAVSVGAVDEVITVARPDAETFEPHVYEAVL
KAVISARAPSLVLMPHSVDSFALAPAVAVGLGLGFATDVFGLAVEDGEVVATRAGYNEKVFVEIDFPGRSGVLVTLRGGA
FAPATVPASPTVSALDAGEGKPRSRHLEWRDPPASGGIDIPGSPFILSIGRGVGDEANVAQFLELAEGLGATLGCSRPIA
DSGWLPKARQVGQSGQLAAKCNLYIAMGISGSVQHQWGMKHVENIVAINKDPEASIFTIARYGIVGDMLEIAEELRKQQG
IQ

Specific function: The electron transfer flavoprotein of this bacterium serves as an electron acceptor specifically for trimethylamine dehydrogenase. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=315, Percent_Identity=31.4285714285714, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI189181759, Length=215, Percent_Identity=36.2790697674419, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1786226, Length=260, Percent_Identity=33.0769230769231, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787990, Length=247, Percent_Identity=31.5789473684211, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17506929, Length=319, Percent_Identity=32.2884012539185, Blast_Score=117, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6325261, Length=171, Percent_Identity=34.5029239766082, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17136898, Length=317, Percent_Identity=33.1230283911672, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24652801, Length=317, Percent_Identity=33.1230283911672, Blast_Score=125, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33412; Mature: 33280

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGILILAEHRRGVLRDATLEAIGAAGELKGALGGPVTVLVIAADPSPFVGAVSVGAVDE
CCCEEEEECCCCCCHHHHHHHHHCCCHHCCCCCCCCEEEEEEEECCCCCEEEEECCCHHH
VITVARPDAETFEPHVYEAVLKAVISARAPSLVLMPHSVDSFALAPAVAVGLGLGFATDV
HHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHH
FGLAVEDGEVVATRAGYNEKVFVEIDFPGRSGVLVTLRGGAFAPATVPASPTVSALDAGE
HEEEECCCCEEEEECCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
GKPRSRHLEWRDPPASGGIDIPGSPFILSIGRGVGDEANVAQFLELAEGLGATLGCSRPI
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
ADSGWLPKARQVGQSGQLAAKCNLYIAMGISGSVQHQWGMKHVENIVAINKDPEASIFTI
CCCCCCCHHHHCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHEEEECCCCCCCEEEE
ARYGIVGDMLEIAEELRKQQGIQ
EHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGILILAEHRRGVLRDATLEAIGAAGELKGALGGPVTVLVIAADPSPFVGAVSVGAVDE
CCEEEEECCCCCCHHHHHHHHHCCCHHCCCCCCCCEEEEEEEECCCCCEEEEECCCHHH
VITVARPDAETFEPHVYEAVLKAVISARAPSLVLMPHSVDSFALAPAVAVGLGLGFATDV
HHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHH
FGLAVEDGEVVATRAGYNEKVFVEIDFPGRSGVLVTLRGGAFAPATVPASPTVSALDAGE
HEEEECCCCEEEEECCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
GKPRSRHLEWRDPPASGGIDIPGSPFILSIGRGVGDEANVAQFLELAEGLGATLGCSRPI
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
ADSGWLPKARQVGQSGQLAAKCNLYIAMGISGSVQHQWGMKHVENIVAINKDPEASIFTI
CCCCCCCHHHHCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHEEEECCCCCCCEEEE
ARYGIVGDMLEIAEELRKQQGIQ
EHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7798207; 12567183 [H]