Click here to switch to the map view.

The map label for this gene is hsdR [H]

Identifier: 154244735

GI number: 154244735

Start: 875442

End: 877817

Strand: Direct

Name: hsdR [H]

Synonym: Xaut_0785

Alternate gene names: 154244735

Gene position: 875442-877817 (Clockwise)

Preceding gene: 154244734

Following gene: 154244736

Centisome position: 16.49

GC content: 63.13

Gene sequence:

>2376_bases
ATGAACACAGAGGCCGACACGTGTCGAAAATTCGTCGTACCCCGTCTGCAGGCCGCCGGATGGGATAACGCGCCTCACGC
AATCAACGAGCAGCGCACCTTCACCGATGGCCGGGTGATCTTCGTCGGGGGTCGTGCTCGCCGCGGCCGGCAGAAGCGGG
CCGACTACATTCTGCGGTTCAGCGCCGATTACCCGATCGCCGTCGTGGAAGCCAAGGCGAGCTACAAGTCCGCCGCCGAT
GGTCTGCAGCAGGCCAAGGACTACGCCGAGATTCTAGGGCTGAAGTTCGCAATCGCCACCAACGGTGCCCAGATCGTGGA
GTTCGACTTCTTCACCGGCGTTGAAACGCTGCGCGCCGACTTTCCAGCACCCGCGGAATTGTGGGCGCGCCAGCGCGCGG
GTCTCGGTTTGGCCGACGATGCTGCGGCCAATCGGCTCCTCACGCCCGGGTTTCCCGACCCAGGCAAGCCGCTGCGCTAC
TATCAAGAAGGTGCGGTCAATCAGGCGCTCCAAGCCATACTTACCGGCAGGCGCCGCGCGCTCTTGACGCTGTGCACCGG
GGCCGGGAAAACGGCGGTGGCTTTCCAGATCGCTTGGCGGCTCTGGAGTGCTGGGTGGAACAAGCGCGGGGATTTCCGCA
AACCGAAGATCCTGTTTCTCGCGGACCGCAATATCCTCGTCGACGATCCGATGGGCAAGACGTTCGCGCCGTTCGGCGAC
GCCCGCTTCAAAATCGAGAATGGTGTCGTCAGCCAGGGCCGCGATATCTATTTCGCGATCTACCAAGCGATCGCCCGGGA
CGAACGAAGGCCGGGACTTTATCGCGAATACGCGCGCGACTTCTTCGATTTAATCATCGTAGACGAATGCCATCGCGGCA
GCGCACGCGACGACAGCAGCTGGCGGGAGATCCTGGAGTATTTCGAGCCGGCATATCAGCTCGGCATGACAGCCACCCCG
CTCAGGGATGACAACCGCGACACCTATGCTTATTTCGGCGCGCCGCTCTACACCTATTCGCTGGCGCAAGGCATCGCGGA
CGGCTTCCTCGCGCCCTATCGCGTGCATCGGGTGGTTACCGACTATGACGCCGTGGGCTGGCGGCCAAGCAAGGGCGAGC
TAGACCGCTTCGGGCGCGAGATTCCCGATGATGAGTATCACACCAGGGATTTCGAGCGGGTGGTCGCACTGCGCGCCCGC
ACGGAAGCGATGGCCCGACACCTCACGCATTTCCTCGCCCAGACGGACCGCTTCGCCAAGACGATCGTCTTCTGCGTCGA
CCAAGAGCATGCGAGCGAGATGCGCCGCGCGCTTGCCAACCTCAACGCTGACCTCGTCGTCGCGTATCCGGACTACGCTT
GTCGCGTCACCGCCGATGAGGGCGACATCGGCAAGGGAAAGCTGAATGCGTTTCAGGATGTGGAAACGAAGGTTCCTGTT
ATCCTCACGACGTCGCAGCTTCTGACGACGGGTGTCGACGCGCCGACTTGCAAGAATGTCGTCCTCGCCCGCGTCGTGGG
CTCGATGACCGAGTTCAAACAGATCATCGGACGCGGCACTCGCCTGCGCGAGGACTACGGCAAGCTGTTCTTCAACATCC
TCGACTACACCGGTACCGCTACAGAAAAGTTCGCCGACCCCGAATTCGACGGCGAACCAACGGCCGAAACGGTTACTGAG
ATCGACGCCGACGGCGAAGTGGTTACGACCGAAGGCGAGGAGAAGCCTCCGCTGGAGACGCCCGACGAGCCGGAAGGCGA
GACGCCGCCGGGTGGGCTGCCGCCGGACGAAGAGCCTGGCGAGCCGCGCAAATATTATGTCGATGGCGGGGCGGTCGAGG
TGGTAGCCCACCTCGTCTACGAGCTCGACACCGACGGCAAGCGTCTGACCTGCAAGAAGCTGATGGATTGGACCGGGGAG
AAGGTCCGAACACTCTATCCGACGGCAGCGAGCTTTCGCGCGGACTGGCTCAATGCCGACAAGCGCCAGGCCGTGGTCGA
AGCGCTCGCCGAGCGCGGCATCGACCTTGAGACCCTAGCGAAGGAGGCGGGCCGTCCAGACGACGATCCCTTCGATCTGC
TCTGCCATCTCGCCTGGAATGCGCCGCTAAGGACTCGCAGGGAGCGCGCAGAACGCCTCAAGCGTGACCGCCAGGACTTC
TTCGATCGTTATGGTGCGGAGGCACGGTCGGTGCTCGAAGCCCTGCTCGAGAAGTATGCCGATCATGGCGCGGCTCAGTT
CGTGCTGCCCGGCATCCTGAAAGTGCCGCCGCTCGCGGGCTTCGGCAATCCCAGTGAAATCGCGCGACGCTTCGGAGGTC
CGGACAAGCTTCGCGCCGCCGTGAATGAAATGTCCGGCCTCTTGTACGCCGCCTAG

Upstream 100 bases:

>100_bases
AAGAGGTCCTCGGCCGGGTCGCCGAGCTCGAGGCGCGCATCAACCAAGCCGGAACCAAGTCGGCGGCGGCAAGGCGAGAC
CGGACGGGGGGCGCAGGAGC

Downstream 100 bases:

>100_bases
GAAAGCACCTCTGAATGCTGCCACGTGAAAAGAAGAAGGATAAGGTGCCGAAGACAACGGCTCAGCGACTCGACAGCGTC
ATCAAGTCTGCGCGCAACAA

Product: EcoEI R domain-containing protein

Products: NA

Alternate protein names: R.EcoAI [H]

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MNTEADTCRKFVVPRLQAAGWDNAPHAINEQRTFTDGRVIFVGGRARRGRQKRADYILRFSADYPIAVVEAKASYKSAAD
GLQQAKDYAEILGLKFAIATNGAQIVEFDFFTGVETLRADFPAPAELWARQRAGLGLADDAAANRLLTPGFPDPGKPLRY
YQEGAVNQALQAILTGRRRALLTLCTGAGKTAVAFQIAWRLWSAGWNKRGDFRKPKILFLADRNILVDDPMGKTFAPFGD
ARFKIENGVVSQGRDIYFAIYQAIARDERRPGLYREYARDFFDLIIVDECHRGSARDDSSWREILEYFEPAYQLGMTATP
LRDDNRDTYAYFGAPLYTYSLAQGIADGFLAPYRVHRVVTDYDAVGWRPSKGELDRFGREIPDDEYHTRDFERVVALRAR
TEAMARHLTHFLAQTDRFAKTIVFCVDQEHASEMRRALANLNADLVVAYPDYACRVTADEGDIGKGKLNAFQDVETKVPV
ILTTSQLLTTGVDAPTCKNVVLARVVGSMTEFKQIIGRGTRLREDYGKLFFNILDYTGTATEKFADPEFDGEPTAETVTE
IDADGEVVTTEGEEKPPLETPDEPEGETPPGGLPPDEEPGEPRKYYVDGGAVEVVAHLVYELDTDGKRLTCKKLMDWTGE
KVRTLYPTAASFRADWLNADKRQAVVEALAERGIDLETLAKEAGRPDDDPFDLLCHLAWNAPLRTRRERAERLKRDRQDF
FDRYGAEARSVLEALLEKYADHGAAQFVLPGILKVPPLAGFGNPSEIARRFGGPDKLRAAVNEMSGLLYAA

Sequences:

>Translated_791_residues
MNTEADTCRKFVVPRLQAAGWDNAPHAINEQRTFTDGRVIFVGGRARRGRQKRADYILRFSADYPIAVVEAKASYKSAAD
GLQQAKDYAEILGLKFAIATNGAQIVEFDFFTGVETLRADFPAPAELWARQRAGLGLADDAAANRLLTPGFPDPGKPLRY
YQEGAVNQALQAILTGRRRALLTLCTGAGKTAVAFQIAWRLWSAGWNKRGDFRKPKILFLADRNILVDDPMGKTFAPFGD
ARFKIENGVVSQGRDIYFAIYQAIARDERRPGLYREYARDFFDLIIVDECHRGSARDDSSWREILEYFEPAYQLGMTATP
LRDDNRDTYAYFGAPLYTYSLAQGIADGFLAPYRVHRVVTDYDAVGWRPSKGELDRFGREIPDDEYHTRDFERVVALRAR
TEAMARHLTHFLAQTDRFAKTIVFCVDQEHASEMRRALANLNADLVVAYPDYACRVTADEGDIGKGKLNAFQDVETKVPV
ILTTSQLLTTGVDAPTCKNVVLARVVGSMTEFKQIIGRGTRLREDYGKLFFNILDYTGTATEKFADPEFDGEPTAETVTE
IDADGEVVTTEGEEKPPLETPDEPEGETPPGGLPPDEEPGEPRKYYVDGGAVEVVAHLVYELDTDGKRLTCKKLMDWTGE
KVRTLYPTAASFRADWLNADKRQAVVEALAERGIDLETLAKEAGRPDDDPFDLLCHLAWNAPLRTRRERAERLKRDRQDF
FDRYGAEARSVLEALLEKYADHGAAQFVLPGILKVPPLAGFGNPSEIARRFGGPDKLRAAVNEMSGLLYAA
>Mature_791_residues
MNTEADTCRKFVVPRLQAAGWDNAPHAINEQRTFTDGRVIFVGGRARRGRQKRADYILRFSADYPIAVVEAKASYKSAAD
GLQQAKDYAEILGLKFAIATNGAQIVEFDFFTGVETLRADFPAPAELWARQRAGLGLADDAAANRLLTPGFPDPGKPLRY
YQEGAVNQALQAILTGRRRALLTLCTGAGKTAVAFQIAWRLWSAGWNKRGDFRKPKILFLADRNILVDDPMGKTFAPFGD
ARFKIENGVVSQGRDIYFAIYQAIARDERRPGLYREYARDFFDLIIVDECHRGSARDDSSWREILEYFEPAYQLGMTATP
LRDDNRDTYAYFGAPLYTYSLAQGIADGFLAPYRVHRVVTDYDAVGWRPSKGELDRFGREIPDDEYHTRDFERVVALRAR
TEAMARHLTHFLAQTDRFAKTIVFCVDQEHASEMRRALANLNADLVVAYPDYACRVTADEGDIGKGKLNAFQDVETKVPV
ILTTSQLLTTGVDAPTCKNVVLARVVGSMTEFKQIIGRGTRLREDYGKLFFNILDYTGTATEKFADPEFDGEPTAETVTE
IDADGEVVTTEGEEKPPLETPDEPEGETPPGGLPPDEEPGEPRKYYVDGGAVEVVAHLVYELDTDGKRLTCKKLMDWTGE
KVRTLYPTAASFRADWLNADKRQAVVEALAERGIDLETLAKEAGRPDDDPFDLLCHLAWNAPLRTRRERAERLKRDRQDF
FDRYGAEARSVLEALLEKYADHGAAQFVLPGILKVPPLAGFGNPSEIARRFGGPDKLRAAVNEMSGLLYAA

Specific function: The EcoAI enzyme recognizes 5'-GAGN(7)GTCA-3'. Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG4096

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI226510991, Length=635, Percent_Identity=27.4015748031496, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320539, Length=397, Percent_Identity=24.1813602015113, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR013670
- InterPro:   IPR007409 [H]

Pfam domain/function: PF08463 EcoEI_R_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 88372; Mature: 88372

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTEADTCRKFVVPRLQAAGWDNAPHAINEQRTFTDGRVIFVGGRARRGRQKRADYILRF
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCEEEEE
SADYPIAVVEAKASYKSAADGLQQAKDYAEILGLKFAIATNGAQIVEFDFFTGVETLRAD
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEHHHHHHHHHHCC
FPAPAELWARQRAGLGLADDAAANRLLTPGFPDPGKPLRYYQEGAVNQALQAILTGRRRA
CCCHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHE
LLTLCTGAGKTAVAFQIAWRLWSAGWNKRGDFRKPKILFLADRNILVDDPMGKTFAPFGD
EEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCC
ARFKIENGVVSQGRDIYFAIYQAIARDERRPGLYREYARDFFDLIIVDECHRGSARDDSS
CEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCHH
WREILEYFEPAYQLGMTATPLRDDNRDTYAYFGAPLYTYSLAQGIADGFLAPYRVHRVVT
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHH
DYDAVGWRPSKGELDRFGREIPDDEYHTRDFERVVALRARTEAMARHLTHFLAQTDRFAK
CCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVFCVDQEHASEMRRALANLNADLVVAYPDYACRVTADEGDIGKGKLNAFQDVETKVPV
HHEEEECHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCCCCCCHHHHHCCCCCE
ILTTSQLLTTGVDAPTCKNVVLARVVGSMTEFKQIIGRGTRLREDYGKLFFNILDYTGTA
EEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
TEKFADPEFDGEPTAETVTEIDADGEVVTTEGEEKPPLETPDEPEGETPPGGLPPDEEPG
HHHCCCCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EPRKYYVDGGAVEVVAHLVYELDTDGKRLTCKKLMDWTGEKVRTLYPTAASFRADWLNAD
CCCEEEECCHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCHHEEECCCHHHHHHHHCCCH
KRQAVVEALAERGIDLETLAKEAGRPDDDPFDLLCHLAWNAPLRTRRERAERLKRDRQDF
HHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FDRYGAEARSVLEALLEKYADHGAAQFVLPGILKVPPLAGFGNPSEIARRFGGPDKLRAA
HHHHCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCCCCCCCHHHHHHHCCCHHHHHHH
VNEMSGLLYAA
HHHHCCCEECC
>Mature Secondary Structure
MNTEADTCRKFVVPRLQAAGWDNAPHAINEQRTFTDGRVIFVGGRARRGRQKRADYILRF
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCEEEEE
SADYPIAVVEAKASYKSAADGLQQAKDYAEILGLKFAIATNGAQIVEFDFFTGVETLRAD
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEHHHHHHHHHHCC
FPAPAELWARQRAGLGLADDAAANRLLTPGFPDPGKPLRYYQEGAVNQALQAILTGRRRA
CCCHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHE
LLTLCTGAGKTAVAFQIAWRLWSAGWNKRGDFRKPKILFLADRNILVDDPMGKTFAPFGD
EEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCC
ARFKIENGVVSQGRDIYFAIYQAIARDERRPGLYREYARDFFDLIIVDECHRGSARDDSS
CEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCHH
WREILEYFEPAYQLGMTATPLRDDNRDTYAYFGAPLYTYSLAQGIADGFLAPYRVHRVVT
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHH
DYDAVGWRPSKGELDRFGREIPDDEYHTRDFERVVALRARTEAMARHLTHFLAQTDRFAK
CCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVFCVDQEHASEMRRALANLNADLVVAYPDYACRVTADEGDIGKGKLNAFQDVETKVPV
HHEEEECHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCCCCCCHHHHHCCCCCE
ILTTSQLLTTGVDAPTCKNVVLARVVGSMTEFKQIIGRGTRLREDYGKLFFNILDYTGTA
EEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
TEKFADPEFDGEPTAETVTEIDADGEVVTTEGEEKPPLETPDEPEGETPPGGLPPDEEPG
HHHCCCCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EPRKYYVDGGAVEVVAHLVYELDTDGKRLTCKKLMDWTGEKVRTLYPTAASFRADWLNAD
CCCEEEECCHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCHHEEECCCHHHHHHHHCCCH
KRQAVVEALAERGIDLETLAKEAGRPDDDPFDLLCHLAWNAPLRTRRERAERLKRDRQDF
HHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FDRYGAEARSVLEALLEKYADHGAAQFVLPGILKVPPLAGFGNPSEIARRFGGPDKLRAA
HHHHCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCCCCCCCHHHHHHHCCCHHHHHHH
VNEMSGLLYAA
HHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412658 [H]