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The map label for this gene is ompR [H]

Identifier: 154244330

GI number: 154244330

Start: 387640

End: 388356

Strand: Direct

Name: ompR [H]

Synonym: Xaut_0373

Alternate gene names: 154244330

Gene position: 387640-388356 (Clockwise)

Preceding gene: 154244324

Following gene: 154244331

Centisome position: 7.3

GC content: 71.41

Gene sequence:

>717_bases
ATGGCTCAGCGCACCCTTCTCCTGGTCGAGGACGACCGCGAAATCCGCTCCCTCCTCGCCGATTTCCTGGGCCGGGAGGG
CTATGGCGTGCTGGCGGCGGAAGACGGCGCGGCCATGGACCGGCTGCTCGCCACCACGCGGCCCGACCTGGTGGTGCTGG
ACCTGATGCTGCCGGGGGAGGACGGGCTCTCCATCTGCCGGCGGCTGCGGGCGCGCAGCGGCCTGCCCATCCTCATGCTC
ACCGCCAAGGCTGACGACGTGGACCGCATCGTCGGGCTCGAAATGGGAGCGGACGACTATCTGGTGAAGCCGTTCAACCC
GCGCGAGCTGCTCGCCCGCATCCGCGCCGTGCTGCGGCGTGCGGACGGGGCCATGCCGCAGCCGCAGTTCCAGTCGCGGC
GCGTGGCCTTCGCCGGCTTCGTGGCGGACCTCGACGCCCGCAGCGTGGGATGCGCCGAGGGCGAGGCGCTGGATCTCACC
TCCGCCGAGTTCGAGCTGCTCGCCTGCTTCCTGGAGCGGCCCAAGCGGGTGCTCTCCCGCGACCAGCTCCTGGACTGGAC
CCGCGGGCGCAGCGCCGATCCCTTCGACCGCACCATCGATGTCTCGGTGAGCCGGTTGAGGCGCAAGCTCGTCGCCGCTG
CGCCCGAGGCGGCCCTGCTCATCAAGACCGTCCGCAACGGCGGCTACCTTTTCGCCGCCGATGTCCGCACCCTCTGA

Upstream 100 bases:

>100_bases
CTTTGCGTCCGGTTTGCGCCGGGGTGAGCTGCTGTAACGTTTTGTAACCACCGCCGCGGCGCGTATTGCTGGCAGCTCCC
GGCTTGGCGACACTTCCCCC

Downstream 100 bases:

>100_bases
AAAGCCCCCCGGCACCCGCTCCAGGGACCGCGCCTTGCCCCGTTTCGGTATCGCCGCGCGCATCGCGATCATTGTCGTCG
GGGCGCTGGTGGTGGTGCAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MAQRTLLLVEDDREIRSLLADFLGREGYGVLAAEDGAAMDRLLATTRPDLVVLDLMLPGEDGLSICRRLRARSGLPILML
TAKADDVDRIVGLEMGADDYLVKPFNPRELLARIRAVLRRADGAMPQPQFQSRRVAFAGFVADLDARSVGCAEGEALDLT
SAEFELLACFLERPKRVLSRDQLLDWTRGRSADPFDRTIDVSVSRLRRKLVAAAPEAALLIKTVRNGGYLFAADVRTL

Sequences:

>Translated_238_residues
MAQRTLLLVEDDREIRSLLADFLGREGYGVLAAEDGAAMDRLLATTRPDLVVLDLMLPGEDGLSICRRLRARSGLPILML
TAKADDVDRIVGLEMGADDYLVKPFNPRELLARIRAVLRRADGAMPQPQFQSRRVAFAGFVADLDARSVGCAEGEALDLT
SAEFELLACFLERPKRVLSRDQLLDWTRGRSADPFDRTIDVSVSRLRRKLVAAAPEAALLIKTVRNGGYLFAADVRTL
>Mature_237_residues
AQRTLLLVEDDREIRSLLADFLGREGYGVLAAEDGAAMDRLLATTRPDLVVLDLMLPGEDGLSICRRLRARSGLPILMLT
AKADDVDRIVGLEMGADDYLVKPFNPRELLARIRAVLRRADGAMPQPQFQSRRVAFAGFVADLDARSVGCAEGEALDLTS
AEFELLACFLERPKRVLSRDQLLDWTRGRSADPFDRTIDVSVSRLRRKLVAAAPEAALLIKTVRNGGYLFAADVRTL

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=49.7835497835498, Blast_Score=208, Evalue=2e-55,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=37.1308016877637, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=41.0480349344978, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=39.3162393162393, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=38.1974248927039, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=40.6113537117904, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=41.2765957446808, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=38.961038961039, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=41.2280701754386, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=36.1233480176211, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786911, Length=210, Percent_Identity=39.0476190476191, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=36.0869565217391, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=35.6521739130435, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=34.061135371179, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790299, Length=145, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=30.188679245283, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26282; Mature: 26151

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRTLLLVEDDREIRSLLADFLGREGYGVLAAEDGAAMDRLLATTRPDLVVLDLMLPGE
CCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEEEECCC
DGLSICRRLRARSGLPILMLTAKADDVDRIVGLEMGADDYLVKPFNPRELLARIRAVLRR
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHEEEECCCCCEECCCCHHHHHHHHHHHHHH
ADGAMPQPQFQSRRVAFAGFVADLDARSVGCAEGEALDLTSAEFELLACFLERPKRVLSR
HCCCCCCCCHHHCEEHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
DQLLDWTRGRSADPFDRTIDVSVSRLRRKLVAAAPEAALLIKTVRNGGYLFAADVRTL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCC
>Mature Secondary Structure 
AQRTLLLVEDDREIRSLLADFLGREGYGVLAAEDGAAMDRLLATTRPDLVVLDLMLPGE
CCCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEEEECCC
DGLSICRRLRARSGLPILMLTAKADDVDRIVGLEMGADDYLVKPFNPRELLARIRAVLRR
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHEEEECCCCCEECCCCHHHHHHHHHHHHHH
ADGAMPQPQFQSRRVAFAGFVADLDARSVGCAEGEALDLTSAEFELLACFLERPKRVLSR
HCCCCCCCCHHHCEEHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
DQLLDWTRGRSADPFDRTIDVSVSRLRRKLVAAAPEAALLIKTVRNGGYLFAADVRTL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]