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The map label for this gene is atoS [H]

Identifier: 154244301

GI number: 154244301

Start: 358413

End: 359792

Strand: Reverse

Name: atoS [H]

Synonym: Xaut_0344

Alternate gene names: 154244301

Gene position: 359792-358413 (Counterclockwise)

Preceding gene: 154244302

Following gene: 154244300

Centisome position: 6.78

GC content: 71.45

Gene sequence:

>1380_bases
ATGCCCATGTCCGAGGGCAAGGACTTTCTCGCCGACAGCCCGCTGGCCCTCGCCAGCGGCGCGCCCGATTTCGGCGCCGT
CGATGCGGAGGAGGCTTGGATCGCCGTCATCCGCAAGATGGACGAGACCTATGCGGAGCTGGTGCGCCAGCAGGTGGAGC
TGGAGGAGAAGAACGCCGCGCTGGAGGAAGCCCAGGGCTTCATCGCCGGCCTGCTCGGCTCCATGACCGACGTGCTCATC
GCCTGCGACCTCGCCGGGCGGGTGGAACAGGTGAACCTCGCCGCCGAACGCGTGTTCGGCCAGTTGGCGGACGCCCTCAC
CGGCCGCCCCCTCGCCGCGCTGCTCGACCCCTCCTCCCCCACCTCTGCCAGCGATGTGCTCGCCACGGCGGCGCGGCGCC
AGCGCATCGCCGACCGGGAATTCACCCTCGCCACGCCGGAAGGCCCTCAGGCGGTCTCGGTGAACGGCGCCCTGCGCTTC
GACCCGCGCGGGCGGCCGGTGGGCGTGGTGCTGGTGGGCCGGCCCATCGGCGAGCTGCGCGCCGCCTACCACGCCCTCGC
CAGCGCCCATGAACATCTCAAGCGCACCCAGCAGCAACTGGTGCATGCGGAGAAGATGGCCTCCCTCGGCCGCCTCGTGG
CCGGCGTCGCCCACGAGCTGAACAATCCCATCTCCTTCGTCTATGGCAATGCCCACGCCCTGAAGCGCTATGCGGAGCGC
CTCATCACCTATCTCGACGCGGTGCATGGGGGCGCCGATGCCGCCGCCCTCGCCCGCACCCGGGGGGAACTGCGCATCGA
CCGGGCGCTGGCCGACATTCCCGCCACCCTCGCCGGCATGCTGGAAGGCGCCGAGCGGGTGCGCGACATCGTGGCGGACC
TGCGCCGCTTCTCCTCCGACAATCGCGAGGCGCGGGAGGTGTTCGACCTCGCCAGCGTGGTGCGCTCGGCGGTGGACTGG
GTGGCGAAATCCCAGATGCCCGACCTCGCCATCCGCGTCGCGATCCCGGAGGGGCTGGAGGCGGTGGGCCATCCCGGCCA
CATCCACCAGGTGCTGATGAATCTCGTCCAGAACGCCGTGGACGCGCTGGAGGGCCGGCCCGACCCGCGCCTCCACATCA
CCGGCGAGCGGCTCGGCGGCCCGGACGGCGAGCGGGTGGCGGTGCGGGTGCACGACAGCGGGCCCGGCATCCCCGAGGAC
ATCCTCGGCCGCATCTTCGATCCCTTCTTCACCACCAAGGCGGTGGGCAAGGGCACGGGGCTCGGCCTCTCCATCTGCTA
CCGTATCGCCGAGGAGCATGACGGACGGCTGGAAGCCGCCAACCACCCGGAGGGCGGCGCCGTCATCTCCCTTATCCTCC
CGTCAGCGGCCCGGCCATGA

Upstream 100 bases:

>100_bases
TGGAGCCGCGCTGAGGGCGGCGTTGCGCTTTTCCCCGGCGCGGGATTAACTCGCGGGTCTTAGCTCCCGCGTCCCAACTC
CCGCGTCAGGACCACGCCCG

Downstream 100 bases:

>100_bases
GCACCCTTGCGCGCGAGCCCTTCACCGTGCTGTGGCTGCAATCGGGCGGCTGCGGCGGCTGCACCATGTCGCTCTTGTGC
GCCGAGGCCCCGGACCTTGC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MPMSEGKDFLADSPLALASGAPDFGAVDAEEAWIAVIRKMDETYAELVRQQVELEEKNAALEEAQGFIAGLLGSMTDVLI
ACDLAGRVEQVNLAAERVFGQLADALTGRPLAALLDPSSPTSASDVLATAARRQRIADREFTLATPEGPQAVSVNGALRF
DPRGRPVGVVLVGRPIGELRAAYHALASAHEHLKRTQQQLVHAEKMASLGRLVAGVAHELNNPISFVYGNAHALKRYAER
LITYLDAVHGGADAAALARTRGELRIDRALADIPATLAGMLEGAERVRDIVADLRRFSSDNREAREVFDLASVVRSAVDW
VAKSQMPDLAIRVAIPEGLEAVGHPGHIHQVLMNLVQNAVDALEGRPDPRLHITGERLGGPDGERVAVRVHDSGPGIPED
ILGRIFDPFFTTKAVGKGTGLGLSICYRIAEEHDGRLEAANHPEGGAVISLILPSAARP

Sequences:

>Translated_459_residues
MPMSEGKDFLADSPLALASGAPDFGAVDAEEAWIAVIRKMDETYAELVRQQVELEEKNAALEEAQGFIAGLLGSMTDVLI
ACDLAGRVEQVNLAAERVFGQLADALTGRPLAALLDPSSPTSASDVLATAARRQRIADREFTLATPEGPQAVSVNGALRF
DPRGRPVGVVLVGRPIGELRAAYHALASAHEHLKRTQQQLVHAEKMASLGRLVAGVAHELNNPISFVYGNAHALKRYAER
LITYLDAVHGGADAAALARTRGELRIDRALADIPATLAGMLEGAERVRDIVADLRRFSSDNREAREVFDLASVVRSAVDW
VAKSQMPDLAIRVAIPEGLEAVGHPGHIHQVLMNLVQNAVDALEGRPDPRLHITGERLGGPDGERVAVRVHDSGPGIPED
ILGRIFDPFFTTKAVGKGTGLGLSICYRIAEEHDGRLEAANHPEGGAVISLILPSAARP
>Mature_458_residues
PMSEGKDFLADSPLALASGAPDFGAVDAEEAWIAVIRKMDETYAELVRQQVELEEKNAALEEAQGFIAGLLGSMTDVLIA
CDLAGRVEQVNLAAERVFGQLADALTGRPLAALLDPSSPTSASDVLATAARRQRIADREFTLATPEGPQAVSVNGALRFD
PRGRPVGVVLVGRPIGELRAAYHALASAHEHLKRTQQQLVHAEKMASLGRLVAGVAHELNNPISFVYGNAHALKRYAERL
ITYLDAVHGGADAAALARTRGELRIDRALADIPATLAGMLEGAERVRDIVADLRRFSSDNREAREVFDLASVVRSAVDWV
AKSQMPDLAIRVAIPEGLEAVGHPGHIHQVLMNLVQNAVDALEGRPDPRLHITGERLGGPDGERVAVRVHDSGPGIPEDI
LGRIFDPFFTTKAVGKGTGLGLSICYRIAEEHDGRLEAANHPEGGAVISLILPSAARP

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=400, Percent_Identity=27, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1790436, Length=260, Percent_Identity=31.1538461538462, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790300, Length=397, Percent_Identity=26.7002518891688, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786912, Length=284, Percent_Identity=28.169014084507, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=303, Percent_Identity=30.03300330033, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788393, Length=133, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=280, Percent_Identity=25.3571428571429, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48994; Mature: 48863

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMSEGKDFLADSPLALASGAPDFGAVDAEEAWIAVIRKMDETYAELVRQQVELEEKNAA
CCCCCCCHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEEAQGFIAGLLGSMTDVLIACDLAGRVEQVNLAAERVFGQLADALTGRPLAALLDPSSP
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
TSASDVLATAARRQRIADREFTLATPEGPQAVSVNGALRFDPRGRPVGVVLVGRPIGELR
CCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEECCEEEECCCCCCEEEEEECCCHHHHH
AAYHALASAHEHLKRTQQQLVHAEKMASLGRLVAGVAHELNNPISFVYGNAHALKRYAER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
LITYLDAVHGGADAAALARTRGELRIDRALADIPATLAGMLEGAERVRDIVADLRRFSSD
HHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NREAREVFDLASVVRSAVDWVAKSQMPDLAIRVAIPEGLEAVGHPGHIHQVLMNLVQNAV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHH
DALEGRPDPRLHITGERLGGPDGERVAVRVHDSGPGIPEDILGRIFDPFFTTKAVGKGTG
HHHCCCCCCCEEEECHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCC
LGLSICYRIAEEHDGRLEAANHPEGGAVISLILPSAARP
CHHHHHHHHHHHCCCCEECCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
PMSEGKDFLADSPLALASGAPDFGAVDAEEAWIAVIRKMDETYAELVRQQVELEEKNAA
CCCCCCHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEEAQGFIAGLLGSMTDVLIACDLAGRVEQVNLAAERVFGQLADALTGRPLAALLDPSSP
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
TSASDVLATAARRQRIADREFTLATPEGPQAVSVNGALRFDPRGRPVGVVLVGRPIGELR
CCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEECCEEEECCCCCCEEEEEECCCHHHHH
AAYHALASAHEHLKRTQQQLVHAEKMASLGRLVAGVAHELNNPISFVYGNAHALKRYAER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
LITYLDAVHGGADAAALARTRGELRIDRALADIPATLAGMLEGAERVRDIVADLRRFSSD
HHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NREAREVFDLASVVRSAVDWVAKSQMPDLAIRVAIPEGLEAVGHPGHIHQVLMNLVQNAV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHH
DALEGRPDPRLHITGERLGGPDGERVAVRVHDSGPGIPEDILGRIFDPFFTTKAVGKGTG
HHHCCCCCCCEEEECHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCC
LGLSICYRIAEEHDGRLEAANHPEGGAVISLILPSAARP
CHHHHHHHHHHHCCCCEECCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]