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The map label for this gene is hbpA [H]

Identifier: 154244247

GI number: 154244247

Start: 294667

End: 296262

Strand: Reverse

Name: hbpA [H]

Synonym: Xaut_0290

Alternate gene names: 154244247

Gene position: 296262-294667 (Counterclockwise)

Preceding gene: 154244248

Following gene: 154244246

Centisome position: 5.58

GC content: 64.66

Gene sequence:

>1596_bases
ATGGCGTTTAGACATTCCCTAGCCGCTGCTTTTTTCGCCGCCGTTGCACTGGCGGCCCCGGCCCGGGCTGAAAGCGTGGT
CCGCTACGGCATCTCCATGGCTGACATTCCCCAGACCACGGGACAGCCTGATCGTGGGGCAGGTGCCTATCAATTCACCG
GCTACACCCTCTACGACCCGCTGGTGGCGTGGGAGATGAACGTGGCCGACCGCCCCGGCAAGCTGGTGCCGGGCCTCGCC
ACCGAATGGAAGGTGGACCCCGCCGACCAGAAGAAGTGGATCTTCACCCTGCGCAAGGGCGTGAAATTCCACGACGGCAG
CGATTTCAACGCCGATGCGGTGGTGTGGAACCTCGACAAGGTGCTGGACGAGAAGGCGCCCCACTACGACAAGCGCCAGG
CCGCCCAGGTGAAGACCCGCCTGCCCGGCATCGCCTCCTGGAAGAAGATCGACGATAATACCGTCGAGATCACCACCAAG
GACGTGGACTCGTTCTTCCCCTACCAGATGCTGTGGTTCCTGGTGTCCAGCCCCGCCCAGTATGAGAAGCTCGGCCGCGA
CTGGGACAAGTTCGCCCAGAGCCCGTCCGGCACCGGGCCGTTCAAGCAGGACAAGCTGGTGCCCCGCGAGCGGCTGGAGC
TGGTCAAGAACCCCGACTATTGGGACAAGACCCGCCTGCCCAAGACCGACCGCATGATCCTCATCCCCATGCCGGAGGCG
CTGACCCGCACCAATGCGCTGCTCGCCGGCCAGGTGGACCTGATCGAGACTCCGGCGCCGGACGCCGTGCCCCAGCTGAA
GTCGGCGGGCATGAAGATCGTCACCAACGTCACCCCGCACGTATGGAACTACCACCTCTCGGTACTGCCCGGCTCGCCCT
GGACCGACGTGCGCCTGCGCAAGGCGCTCAACCTCGCCGTGGATCGCGACGGCGTGGTGGAGCTGATGAACGGCCTCGCC
AAGCCGGCCAAGGGTCAGGTCGACGTGTCCAGCCCCTGGTTCGGCAAGCCGGAGTTCGACCTCAAGTATGATCCCGAGGC
CGCCAAGAAGCTGGTGAAGGAAGCCGGCTATTCCCCCGAGAAGCCGCTGAAGGCCACCTTCATCATCGCCGCGGGCGGTA
CCGGCCAGATGCTCTCCCTGCCCATGAACGAGTTCCTGCAGGCGAGCTTCAAGGAAATCGGCGTGGACGTGGAGTTCAAG
GTAGTGGAGCTGGAGGCGCTCTATACCGCCTGGCGCAAGGGGGCGAAGGACCCCTCGAACGCGGGCATCACCGCCAACAA
CATCGCCTATGTGACCTCGGACCCGCTCTACGCCCTCATCCGCTTCTTCGACAGCCGGCAGGTGGCGCCGGTGGGCGTCA
ACTGGGGCTTTTATGCCAACCCCAAGGTGGACGCACTGATCGACGAGGCCAAGCACACCTTCGACACCCAGAAGCAGGAC
GCGCTGCTGGCCCAGGTACACCAGACCGTCGTGGACGACGCGGTGCTGGTGTGGGTGGTGCATGACACCAACCCGCATGC
GCTCTCGCCCAAGGTGAAGAGCTTCGTGCAGGCCCAGCACTGGTTCCAGGACCTGACCACCATCGGGATGCAGTAG

Upstream 100 bases:

>100_bases
GGGCGAACCTTTCTGAGCTGAGCGTATCTGGCGCATTGCATACAATGCGGCATGCGTCTTGCGTTGCTTCCGTGGGGGCA
CTCCACGGAAGGACGTTTTC

Downstream 100 bases:

>100_bases
CACCTTCTCCCGTCGGACCCGGCAGCACGGCAAACGCCGAGGTCGCAGCATCTGCGTTCAGGTCTGCGGCCTCGACCGGC
CCACCGTGGACCCCTCTCCC

Product: extracellular solute-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MAFRHSLAAAFFAAVALAAPARAESVVRYGISMADIPQTTGQPDRGAGAYQFTGYTLYDPLVAWEMNVADRPGKLVPGLA
TEWKVDPADQKKWIFTLRKGVKFHDGSDFNADAVVWNLDKVLDEKAPHYDKRQAAQVKTRLPGIASWKKIDDNTVEITTK
DVDSFFPYQMLWFLVSSPAQYEKLGRDWDKFAQSPSGTGPFKQDKLVPRERLELVKNPDYWDKTRLPKTDRMILIPMPEA
LTRTNALLAGQVDLIETPAPDAVPQLKSAGMKIVTNVTPHVWNYHLSVLPGSPWTDVRLRKALNLAVDRDGVVELMNGLA
KPAKGQVDVSSPWFGKPEFDLKYDPEAAKKLVKEAGYSPEKPLKATFIIAAGGTGQMLSLPMNEFLQASFKEIGVDVEFK
VVELEALYTAWRKGAKDPSNAGITANNIAYVTSDPLYALIRFFDSRQVAPVGVNWGFYANPKVDALIDEAKHTFDTQKQD
ALLAQVHQTVVDDAVLVWVVHDTNPHALSPKVKSFVQAQHWFQDLTTIGMQ

Sequences:

>Translated_531_residues
MAFRHSLAAAFFAAVALAAPARAESVVRYGISMADIPQTTGQPDRGAGAYQFTGYTLYDPLVAWEMNVADRPGKLVPGLA
TEWKVDPADQKKWIFTLRKGVKFHDGSDFNADAVVWNLDKVLDEKAPHYDKRQAAQVKTRLPGIASWKKIDDNTVEITTK
DVDSFFPYQMLWFLVSSPAQYEKLGRDWDKFAQSPSGTGPFKQDKLVPRERLELVKNPDYWDKTRLPKTDRMILIPMPEA
LTRTNALLAGQVDLIETPAPDAVPQLKSAGMKIVTNVTPHVWNYHLSVLPGSPWTDVRLRKALNLAVDRDGVVELMNGLA
KPAKGQVDVSSPWFGKPEFDLKYDPEAAKKLVKEAGYSPEKPLKATFIIAAGGTGQMLSLPMNEFLQASFKEIGVDVEFK
VVELEALYTAWRKGAKDPSNAGITANNIAYVTSDPLYALIRFFDSRQVAPVGVNWGFYANPKVDALIDEAKHTFDTQKQD
ALLAQVHQTVVDDAVLVWVVHDTNPHALSPKVKSFVQAQHWFQDLTTIGMQ
>Mature_530_residues
AFRHSLAAAFFAAVALAAPARAESVVRYGISMADIPQTTGQPDRGAGAYQFTGYTLYDPLVAWEMNVADRPGKLVPGLAT
EWKVDPADQKKWIFTLRKGVKFHDGSDFNADAVVWNLDKVLDEKAPHYDKRQAAQVKTRLPGIASWKKIDDNTVEITTKD
VDSFFPYQMLWFLVSSPAQYEKLGRDWDKFAQSPSGTGPFKQDKLVPRERLELVKNPDYWDKTRLPKTDRMILIPMPEAL
TRTNALLAGQVDLIETPAPDAVPQLKSAGMKIVTNVTPHVWNYHLSVLPGSPWTDVRLRKALNLAVDRDGVVELMNGLAK
PAKGQVDVSSPWFGKPEFDLKYDPEAAKKLVKEAGYSPEKPLKATFIIAAGGTGQMLSLPMNEFLQASFKEIGVDVEFKV
VELEALYTAWRKGAKDPSNAGITANNIAYVTSDPLYALIRFFDSRQVAPVGVNWGFYANPKVDALIDEAKHTFDTQKQDA
LLAQVHQTVVDDAVLVWVVHDTNPHALSPKVKSFVQAQHWFQDLTTIGMQ

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=542, Percent_Identity=24.9077490774908, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789966, Length=510, Percent_Identity=24.7058823529412, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1787052, Length=426, Percent_Identity=28.4037558685446, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1789397, Length=467, Percent_Identity=24.8394004282655, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789887, Length=468, Percent_Identity=25.6410256410256, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87081878, Length=480, Percent_Identity=23.125, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787762, Length=474, Percent_Identity=24.8945147679325, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59080; Mature: 58949

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFRHSLAAAFFAAVALAAPARAESVVRYGISMADIPQTTGQPDRGAGAYQFTGYTLYDP
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCEEECCEEEECC
LVAWEMNVADRPGKLVPGLATEWKVDPADQKKWIFTLRKGVKFHDGSDFNADAVVWNLDK
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEECCCCCCCCCEEEEEHHH
VLDEKAPHYDKRQAAQVKTRLPGIASWKKIDDNTVEITTKDVDSFFPYQMLWFLVSSPAQ
HHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHCHHHHHHHHHCCCHH
YEKLGRDWDKFAQSPSGTGPFKQDKLVPRERLELVKNPDYWDKTRLPKTDRMILIPMPEA
HHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHH
LTRTNALLAGQVDLIETPAPDAVPQLKSAGMKIVTNVTPHVWNYHLSVLPGSPWTDVRLR
HHHCCCEEECCEEEECCCCCCHHHHHHHCCCEEEECCCCCEEEEEEEEECCCCCHHHHHH
KALNLAVDRDGVVELMNGLAKPAKGQVDVSSPWFGKPEFDLKYDPEAAKKLVKEAGYSPE
HHHHHHCCCCCHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
KPLKATFIIAAGGTGQMLSLPMNEFLQASFKEIGVDVEFKVVELEALYTAWRKGAKDPSN
CCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCC
AGITANNIAYVTSDPLYALIRFFDSRQVAPVGVNWGFYANPKVDALIDEAKHTFDTQKQD
CCEEECCEEEEECCHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHH
ALLAQVHQTVVDDAVLVWVVHDTNPHALSPKVKSFVQAQHWFQDLTTIGMQ
HHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFRHSLAAAFFAAVALAAPARAESVVRYGISMADIPQTTGQPDRGAGAYQFTGYTLYDP
CCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCEEECCEEEECC
LVAWEMNVADRPGKLVPGLATEWKVDPADQKKWIFTLRKGVKFHDGSDFNADAVVWNLDK
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEECCCCCCCCCEEEEEHHH
VLDEKAPHYDKRQAAQVKTRLPGIASWKKIDDNTVEITTKDVDSFFPYQMLWFLVSSPAQ
HHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHCHHHHHHHHHCCCHH
YEKLGRDWDKFAQSPSGTGPFKQDKLVPRERLELVKNPDYWDKTRLPKTDRMILIPMPEA
HHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHH
LTRTNALLAGQVDLIETPAPDAVPQLKSAGMKIVTNVTPHVWNYHLSVLPGSPWTDVRLR
HHHCCCEEECCEEEECCCCCCHHHHHHHCCCEEEECCCCCEEEEEEEEECCCCCHHHHHH
KALNLAVDRDGVVELMNGLAKPAKGQVDVSSPWFGKPEFDLKYDPEAAKKLVKEAGYSPE
HHHHHHCCCCCHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
KPLKATFIIAAGGTGQMLSLPMNEFLQASFKEIGVDVEFKVVELEALYTAWRKGAKDPSN
CCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCC
AGITANNIAYVTSDPLYALIRFFDSRQVAPVGVNWGFYANPKVDALIDEAKHTFDTQKQD
CCEEECCEEEEECCHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHH
ALLAQVHQTVVDDAVLVWVVHDTNPHALSPKVKSFVQAQHWFQDLTTIGMQ
HHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]