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The map label for this gene is kup

Identifier: 154244143

GI number: 154244143

Start: 184257

End: 186143

Strand: Reverse

Name: kup

Synonym: Xaut_0185

Alternate gene names: 154244143

Gene position: 186143-184257 (Counterclockwise)

Preceding gene: 154244144

Following gene: 154244142

Centisome position: 3.51

GC content: 67.51

Gene sequence:

>1887_bases
ATGGCCCTCAGCTTTTCCCGCGACCGCACACGCCCCCTGCCGTTCGCCGCCGAGATCGGCGCCCTCGGCGTGGTGTTCGG
CGATATCGGCACCAGCCCGCTCTATGCCCTCAAGCAGGGCGTGCTCGCAGTGGGCGGCACCAATTTCCTCGGCGGCGACG
TGCTGGGGCTGCTCTCGCTCATCACCTGGAGCATCATTCTTTCCGTCACCGTGAAATACGTGATGCTGGTGCTGCGGGCG
GACAACGACGGCGAAGGCGGCATCCTGGCCCTCGTCACCCTGCTCGACCTCCACCGCAGCGCGCTCGGCATGCGCTGGTA
CCTGCTGGCCGCCGGCCTGCTGGGCGCCGCCATGCTCATCGGTGACGGCGTGCTGACCCCGGCCATGTCGGTACTCTCGG
CCATCGAGGGTCTCCAGGTCATATCGCCGGAGCTGGAGCACTGGGTGGTGACGCTCACCGTGCTGGTGCTGCTCGCCGTC
TTCCTGTCGCAGCGGCTGGGAACCGAGCGTATCGCCTCCTTCTTCGGCCCCATCATGCTGATGTGGTTCGGCTCGCTGGG
GGCGCTGGGCGTCTACGGCATCCTGCAGGCGCCCCAGGTGCTCGCCGGGCTCGACCCGCGCTACGGCATCATGCTGATGG
TGAACCATCCCGGGCTTGCCGGCGTCATCCTCGGCGCCTGCTTCCTGGCGGTGACGGGTGGCGAGGCGCTCTATGCGGAC
CTTGGCCATTTCGGCCGCCCGGTCATCGCGCGGGCCTGGCTGTTCGTGGCCATGCCGGCGCTGCTGCTCAATTATTTCGG
CCAGGGCGCGATCCTGCTGGTGGATCCGAACGCGGTGCGCAACCCGTTCTATGACCTGTGCCCGGACGTGTTCGACATCC
CGCTGCTATTCCTCGCCACGGCGGCCACGGTGATCGCCTCCCAGTCCATCATCACCGGCGTGTTCTCGCTGGCCAAGCAG
GCCATCGAGCTGGGCTACCTGCCGCCCATGCGCATCCGCTACACCTCCGAGCACAACGAGCAGCACATCTATGTGGGCCG
GCTGAACTGGCTGCTGATGATCGCCTGCATCGCGGTGGTGCTGGGCTTCGAGGCCTCCGACCGGTTGGCCTCGGCCTACG
GTATCGCGGTGGCCTTCGCCATGGTCACCACCTCCATCCTGTTCATCGCCCAGGTGCACCGCTCCTGGGGCTGGCCGGCG
CCGGCGGTGTGGGCCATGGCCACGGGCCTCCTCACCATCGACTTCGCCTTCGCCTCGGCCAACATGACCAAGATCCATGA
CGGTGGCTGGCTGCCCCTGAGCATCGCCGCCGCCATCATCTTCGTGATGGTGAGCTGGCGGCGCGGGCTGGAGGGCGTGG
TGGCCCAGCAGGTCCGCTTCACCGAGCCCCTCGACAGCTTCGTCGCCCGCAAGGACCGGGTGAACGACGTGGAAGCCCCC
CGCACCGCCATCTTTCTGTCTCGTGCGGGTGCCATGACTCCGGTCGCCCTCTCGCGCATGGCCGACTTGCTGAAGGTCCG
GTTCGAGAAGGCGGTGATCGTTTCAGTCTGGATCGCCGCGCGGCCCCGGGTCTCGGTGGAGGACCGGGTGAAGGTGACGA
CCCTCAACGAGGGCTTCGTGCGGGTGGATCTGCGGTTCGGCTACATGCAGCAGATCGACGTTCCCTCCGTGCTCGGCCCG
GCGCTCAGCGCCCGCGGCATCGATCCGGACGCGGCCATCTATGTAATCGGCCACGAACGGATCATCCCGCCCGACGAGGT
GACGAAGATCAAGGACGTGGTGGCGCATGTGTTCGCCTTCCTCGCCCGCAACGCGGAGCGCTCGGTGGACCGGTTCGGCC
TGCCGCGGGCCCGCACGGTGGAGATCGGTTACCCGGTGAAGCTTTAA

Upstream 100 bases:

>100_bases
TGCGGCGCCTTTGTGCATCGCGGCACAGACGAGAGCCTCGCCGGCCGGCACCGCCCCTCCCCCCTGCCCGACGCGCGGCA
CTGAGCGGCGACCGCCCTCG

Downstream 100 bases:

>100_bases
AGGGCATGCACCGGCAGGCGCCGCGTTGTCACGGGCGGTGCAGTATTGACCAATCGGCAGGCCGCCACGGACCGGCGGCC
ATCGCTGCGCCGGCCATAGA

Product: K potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MALSFSRDRTRPLPFAAEIGALGVVFGDIGTSPLYALKQGVLAVGGTNFLGGDVLGLLSLITWSIILSVTVKYVMLVLRA
DNDGEGGILALVTLLDLHRSALGMRWYLLAAGLLGAAMLIGDGVLTPAMSVLSAIEGLQVISPELEHWVVTLTVLVLLAV
FLSQRLGTERIASFFGPIMLMWFGSLGALGVYGILQAPQVLAGLDPRYGIMLMVNHPGLAGVILGACFLAVTGGEALYAD
LGHFGRPVIARAWLFVAMPALLLNYFGQGAILLVDPNAVRNPFYDLCPDVFDIPLLFLATAATVIASQSIITGVFSLAKQ
AIELGYLPPMRIRYTSEHNEQHIYVGRLNWLLMIACIAVVLGFEASDRLASAYGIAVAFAMVTTSILFIAQVHRSWGWPA
PAVWAMATGLLTIDFAFASANMTKIHDGGWLPLSIAAAIIFVMVSWRRGLEGVVAQQVRFTEPLDSFVARKDRVNDVEAP
RTAIFLSRAGAMTPVALSRMADLLKVRFEKAVIVSVWIAARPRVSVEDRVKVTTLNEGFVRVDLRFGYMQQIDVPSVLGP
ALSARGIDPDAAIYVIGHERIIPPDEVTKIKDVVAHVFAFLARNAERSVDRFGLPRARTVEIGYPVKL

Sequences:

>Translated_628_residues
MALSFSRDRTRPLPFAAEIGALGVVFGDIGTSPLYALKQGVLAVGGTNFLGGDVLGLLSLITWSIILSVTVKYVMLVLRA
DNDGEGGILALVTLLDLHRSALGMRWYLLAAGLLGAAMLIGDGVLTPAMSVLSAIEGLQVISPELEHWVVTLTVLVLLAV
FLSQRLGTERIASFFGPIMLMWFGSLGALGVYGILQAPQVLAGLDPRYGIMLMVNHPGLAGVILGACFLAVTGGEALYAD
LGHFGRPVIARAWLFVAMPALLLNYFGQGAILLVDPNAVRNPFYDLCPDVFDIPLLFLATAATVIASQSIITGVFSLAKQ
AIELGYLPPMRIRYTSEHNEQHIYVGRLNWLLMIACIAVVLGFEASDRLASAYGIAVAFAMVTTSILFIAQVHRSWGWPA
PAVWAMATGLLTIDFAFASANMTKIHDGGWLPLSIAAAIIFVMVSWRRGLEGVVAQQVRFTEPLDSFVARKDRVNDVEAP
RTAIFLSRAGAMTPVALSRMADLLKVRFEKAVIVSVWIAARPRVSVEDRVKVTTLNEGFVRVDLRFGYMQQIDVPSVLGP
ALSARGIDPDAAIYVIGHERIIPPDEVTKIKDVVAHVFAFLARNAERSVDRFGLPRARTVEIGYPVKL
>Mature_627_residues
ALSFSRDRTRPLPFAAEIGALGVVFGDIGTSPLYALKQGVLAVGGTNFLGGDVLGLLSLITWSIILSVTVKYVMLVLRAD
NDGEGGILALVTLLDLHRSALGMRWYLLAAGLLGAAMLIGDGVLTPAMSVLSAIEGLQVISPELEHWVVTLTVLVLLAVF
LSQRLGTERIASFFGPIMLMWFGSLGALGVYGILQAPQVLAGLDPRYGIMLMVNHPGLAGVILGACFLAVTGGEALYADL
GHFGRPVIARAWLFVAMPALLLNYFGQGAILLVDPNAVRNPFYDLCPDVFDIPLLFLATAATVIASQSIITGVFSLAKQA
IELGYLPPMRIRYTSEHNEQHIYVGRLNWLLMIACIAVVLGFEASDRLASAYGIAVAFAMVTTSILFIAQVHRSWGWPAP
AVWAMATGLLTIDFAFASANMTKIHDGGWLPLSIAAAIIFVMVSWRRGLEGVVAQQVRFTEPLDSFVARKDRVNDVEAPR
TAIFLSRAGAMTPVALSRMADLLKVRFEKAVIVSVWIAARPRVSVEDRVKVTTLNEGFVRVDLRFGYMQQIDVPSVLGPA
LSARGIDPDAAIYVIGHERIIPPDEVTKIKDVVAHVFAFLARNAERSVDRFGLPRARTVEIGYPVKL

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=627, Percent_Identity=39.3939393939394, Blast_Score=441, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_XANP2 (A7IBQ1)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001415101.1
- STRING:   A7IBQ1
- GeneID:   5421980
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_0185
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   HERIIPP
- ProtClustDB:   CLSK2793502
- BioCyc:   XAUT78245:XAUT_0185-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 67860; Mature: 67729

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd4ccf80)-; HASH(0xc989af0)-; HASH(0xd50aad0)-; HASH(0xdb3d070)-; HASH(0xd5e88e4)-; HASH(0xd293c88)-; HASH(0xb55c6e4)-; HASH(0xdc9714c)-; HASH(0xd28be20)-; HASH(0xdc971a0)-; HASH(0xc202e30)-; HASH(0xd220b60)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSFSRDRTRPLPFAAEIGALGVVFGDIGTSPLYALKQGVLAVGGTNFLGGDVLGLLSL
CCCCCCCCCCCCCCHHHHHCCHHEEEECCCCCHHHHHHCCCEEECCCCCCCHHHHHHHHH
ITWSIILSVTVKYVMLVLRADNDGEGGILALVTLLDLHRSALGMRWYLLAAGLLGAAMLI
HHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDGVLTPAMSVLSAIEGLQVISPELEHWVVTLTVLVLLAVFLSQRLGTERIASFFGPIML
CCCHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MWFGSLGALGVYGILQAPQVLAGLDPRYGIMLMVNHPGLAGVILGACFLAVTGGEALYAD
HHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHH
LGHFGRPVIARAWLFVAMPALLLNYFGQGAILLVDPNAVRNPFYDLCPDVFDIPLLFLAT
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCHHHHCCCHHHHHHHHHHH
AATVIASQSIITGVFSLAKQAIELGYLPPMRIRYTSEHNEQHIYVGRLNWLLMIACIAVV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHH
LGFEASDRLASAYGIAVAFAMVTTSILFIAQVHRSWGWPAPAVWAMATGLLTIDFAFASA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEECC
NMTKIHDGGWLPLSIAAAIIFVMVSWRRGLEGVVAQQVRFTEPLDSFVARKDRVNDVEAP
CCEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC
RTAIFLSRAGAMTPVALSRMADLLKVRFEKAVIVSVWIAARPRVSVEDRVKVTTLNEGFV
HHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEECCCEE
RVDLRFGYMQQIDVPSVLGPALSARGIDPDAAIYVIGHERIIPPDEVTKIKDVVAHVFAF
EEEEEECCHHHCCCCHHHCCHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LARNAERSVDRFGLPRARTVEIGYPVKL
HHHHHHHHHHHHCCCCCEEEECCCCCCH
>Mature Secondary Structure 
ALSFSRDRTRPLPFAAEIGALGVVFGDIGTSPLYALKQGVLAVGGTNFLGGDVLGLLSL
CCCCCCCCCCCCCHHHHHCCHHEEEECCCCCHHHHHHCCCEEECCCCCCCHHHHHHHHH
ITWSIILSVTVKYVMLVLRADNDGEGGILALVTLLDLHRSALGMRWYLLAAGLLGAAMLI
HHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDGVLTPAMSVLSAIEGLQVISPELEHWVVTLTVLVLLAVFLSQRLGTERIASFFGPIML
CCCHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MWFGSLGALGVYGILQAPQVLAGLDPRYGIMLMVNHPGLAGVILGACFLAVTGGEALYAD
HHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHH
LGHFGRPVIARAWLFVAMPALLLNYFGQGAILLVDPNAVRNPFYDLCPDVFDIPLLFLAT
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCHHHHCCCHHHHHHHHHHH
AATVIASQSIITGVFSLAKQAIELGYLPPMRIRYTSEHNEQHIYVGRLNWLLMIACIAVV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHH
LGFEASDRLASAYGIAVAFAMVTTSILFIAQVHRSWGWPAPAVWAMATGLLTIDFAFASA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEECC
NMTKIHDGGWLPLSIAAAIIFVMVSWRRGLEGVVAQQVRFTEPLDSFVARKDRVNDVEAP
CCEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC
RTAIFLSRAGAMTPVALSRMADLLKVRFEKAVIVSVWIAARPRVSVEDRVKVTTLNEGFV
HHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEECCCEE
RVDLRFGYMQQIDVPSVLGPALSARGIDPDAAIYVIGHERIIPPDEVTKIKDVVAHVFAF
EEEEEECCHHHCCCCHHHCCHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LARNAERSVDRFGLPRARTVEIGYPVKL
HHHHHHHHHHHHCCCCCEEEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA