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The map label for this gene is fabA [H]

Identifier: 154244012

GI number: 154244012

Start: 57930

End: 58487

Strand: Reverse

Name: fabA [H]

Synonym: Xaut_0054

Alternate gene names: 154244012

Gene position: 58487-57930 (Counterclockwise)

Preceding gene: 154244014

Following gene: 154244011

Centisome position: 1.1

GC content: 65.95

Gene sequence:

>558_bases
ATGGCGACACGCTTGAGAATGGCGGACCGGCAAACCAGCTTCGCATATGAAGATCTCCTCGCCTGCGGACGTGGCGAGCT
GTTCGGCGCCGGAAACGCGCAATTGCCGCTGCCGCCCATGCTGATGTTCGACCGCATCGTCGAGATTTCCGAGACCGGCG
GCGAATTCGGCAAGGGCTTCATCCGCGCCGAGCTCGACGTGAACCCGGACCTGTGGTTCTTCGCCTGCCACTTCAAGGGC
GACCCGGTTATGCCCGGCTGCCTGGGCCTCGACGCCATGTGGCAGTTGGTCGGCTTCTATCTCGGCTGGCTGGGCTCGCC
CGGCCGCGGCCGGGCGCTGGGCCTCGGCGAACTCAAGTTTTCAGGCCAGGTTCTGCCGGGCGTGAAGAAGGTGGTCTACG
GCATCGAGTTCAAGCGGGTGATGCGCTCCAAGCTGGTGCTGGGCATCGCCGATGGCTGGCTGTCGGCGGACGATGCCGTC
ATCTATCGCGCGAAGGATCTGAAGGTGGGCCTGTTCCAGGCCGATGCGGCACCCGCCGCGGGAGCGGCGAGCGCCTGA

Upstream 100 bases:

>100_bases
ATGTTAGGGAGTGCCCGCCGCCGATGACGGGGGCGGGCCTTAGGGCTCTTTCGGCAACACCCCCAGGGGTCCCCTCGCGG
ATCAACCCCTTCCGGGCAGA

Downstream 100 bases:

>100_bases
CAAGGCGCCGCCACGATCCGCGGCCATACTGCTGCTTTCCAATGGGGATTTGACATGCGGCGCGTCGTCGTCACCGGGAT
GGGCATCGTCTCGTCTATCG

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MATRLRMADRQTSFAYEDLLACGRGELFGAGNAQLPLPPMLMFDRIVEISETGGEFGKGFIRAELDVNPDLWFFACHFKG
DPVMPGCLGLDAMWQLVGFYLGWLGSPGRGRALGLGELKFSGQVLPGVKKVVYGIEFKRVMRSKLVLGIADGWLSADDAV
IYRAKDLKVGLFQADAAPAAGAASA

Sequences:

>Translated_185_residues
MATRLRMADRQTSFAYEDLLACGRGELFGAGNAQLPLPPMLMFDRIVEISETGGEFGKGFIRAELDVNPDLWFFACHFKG
DPVMPGCLGLDAMWQLVGFYLGWLGSPGRGRALGLGELKFSGQVLPGVKKVVYGIEFKRVMRSKLVLGIADGWLSADDAV
IYRAKDLKVGLFQADAAPAAGAASA
>Mature_184_residues
ATRLRMADRQTSFAYEDLLACGRGELFGAGNAQLPLPPMLMFDRIVEISETGGEFGKGFIRAELDVNPDLWFFACHFKGD
PVMPGCLGLDAMWQLVGFYLGWLGSPGRGRALGLGELKFSGQVLPGVKKVVYGIEFKRVMRSKLVLGIADGWLSADDAVI
YRAKDLKVGLFQADAAPAAGAASA

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=171, Percent_Identity=66.6666666666667, Blast_Score=245, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 19949; Mature: 19818

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRLRMADRQTSFAYEDLLACGRGELFGAGNAQLPLPPMLMFDRIVEISETGGEFGKGF
CCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCE
IRAELDVNPDLWFFACHFKGDPVMPGCLGLDAMWQLVGFYLGWLGSPGRGRALGLGELKF
EEEEEECCCCEEEEEEEECCCCCCCCHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEE
SGQVLPGVKKVVYGIEFKRVMRSKLVLGIADGWLSADDAVIYRAKDLKVGLFQADAAPAA
CCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEECCCEEEEEECCCCCCC
GAASA
CCCCC
>Mature Secondary Structure 
ATRLRMADRQTSFAYEDLLACGRGELFGAGNAQLPLPPMLMFDRIVEISETGGEFGKGF
CCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCE
IRAELDVNPDLWFFACHFKGDPVMPGCLGLDAMWQLVGFYLGWLGSPGRGRALGLGELKF
EEEEEECCCCEEEEEEEECCCCCCCCHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEE
SGQVLPGVKKVVYGIEFKRVMRSKLVLGIADGWLSADDAVIYRAKDLKVGLFQADAAPAA
CCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEECCCEEEEEECCCCCCC
GAASA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA