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The map label for this gene is fae [H]

Identifier: 154243990

GI number: 154243990

Start: 31646

End: 32155

Strand: Reverse

Name: fae [H]

Synonym: Xaut_0032

Alternate gene names: 154243990

Gene position: 32155-31646 (Counterclockwise)

Preceding gene: 154243994

Following gene: 154243986

Centisome position: 0.61

GC content: 64.51

Gene sequence:

>510_bases
GTGGCTAAGATTAACAAGGTTCTGATCGGTGAAGCGCTTGTCGGCGACGGCAACGAGGTGGCTCACATCGATCTCATCAT
CGGGCCGCGCGGCAGCGCCGCCGAGACGGCGTTCTGCAACAGCCTCACCAACAACAAGGACGGCTTCACCTCGCTTCTCG
CGGTGCTCGCCCCCAACATGCCCTGCAAGCCCAACACCCTGTTGTTCAACAAGGTGACCATCAAGGATGCGCGGCAGGCG
GTGCAGATGTTCGGACCCGCGCAGCGCGGCGTCGCCAAGGCGGTGCAGGACGCGGTGGCCGAAGGCACCATCCCCGTGGA
CGAGGCCGACGACCTCTACATCTCCGTCGGCGTGTTCATCCACTGGGAAGCGGCGGATGACGCCAAGATCCAGCAGTACA
ACTACGAGGCGACCAAGCTCTCCATCGAGCGCGCCGTGGCGGGTTACCCCTCCGCCAAGGAAGCGACCGAGCAGCGCGAT
CTGGTGAAGCACCCCTTCGCGGCGGCCTAG

Upstream 100 bases:

>100_bases
TCCTGCCGGGCGCTGACAACAAGGGTAGGCGGCATATGACCGCTTCCCGGAATGCCTTCGGGGCGGTCATCCCTGTTCGA
TCTACGAGGGAGGGCATAAG

Downstream 100 bases:

>100_bases
AGCGGAAACCACCCTGGGCAGAGCGGCGACCTTCCGGCGATGCCGAAGGGTCTGCTTCAGCGGTTGGCCGCCCTATTTTT
CAACAAGTAAGTCTGAAGCG

Product: formaldehyde-activating protein

Products: NA

Alternate protein names: Fae [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MAKINKVLIGEALVGDGNEVAHIDLIIGPRGSAAETAFCNSLTNNKDGFTSLLAVLAPNMPCKPNTLLFNKVTIKDARQA
VQMFGPAQRGVAKAVQDAVAEGTIPVDEADDLYISVGVFIHWEAADDAKIQQYNYEATKLSIERAVAGYPSAKEATEQRD
LVKHPFAAA

Sequences:

>Translated_169_residues
MAKINKVLIGEALVGDGNEVAHIDLIIGPRGSAAETAFCNSLTNNKDGFTSLLAVLAPNMPCKPNTLLFNKVTIKDARQA
VQMFGPAQRGVAKAVQDAVAEGTIPVDEADDLYISVGVFIHWEAADDAKIQQYNYEATKLSIERAVAGYPSAKEATEQRD
LVKHPFAAA
>Mature_168_residues
AKINKVLIGEALVGDGNEVAHIDLIIGPRGSAAETAFCNSLTNNKDGFTSLLAVLAPNMPCKPNTLLFNKVTIKDARQAV
QMFGPAQRGVAKAVQDAVAEGTIPVDEADDLYISVGVFIHWEAADDAKIQQYNYEATKLSIERAVAGYPSAKEATEQRDL
VKHPFAAA

Specific function: Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin. Is an essential enzyme for methylotrophic energy metabolism and formaldehyde detoxification of this bacterium [H]

COG id: COG1795

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the formaldehyde-activating enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014826
- InterPro:   IPR020568 [H]

Pfam domain/function: PF08714 Fae [H]

EC number: NA

Molecular weight: Translated: 18069; Mature: 17937

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKINKVLIGEALVGDGNEVAHIDLIIGPRGSAAETAFCNSLTNNKDGFTSLLAVLAPNM
CCCCCCEEECCEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCC
PCKPNTLLFNKVTIKDARQAVQMFGPAQRGVAKAVQDAVAEGTIPVDEADDLYISVGVFI
CCCCCEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEE
HWEAADDAKIQQYNYEATKLSIERAVAGYPSAKEATEQRDLVKHPFAAA
EEECCCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AKINKVLIGEALVGDGNEVAHIDLIIGPRGSAAETAFCNSLTNNKDGFTSLLAVLAPNM
CCCCCEEECCEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCC
PCKPNTLLFNKVTIKDARQAVQMFGPAQRGVAKAVQDAVAEGTIPVDEADDLYISVGVFI
CCCCCEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEE
HWEAADDAKIQQYNYEATKLSIERAVAGYPSAKEATEQRDLVKHPFAAA
EEECCCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9651254; 11073907 [H]