Click here to switch to the map view.

The map label for this gene is obgE [H]

Identifier: 153952548

GI number: 153952548

Start: 106654

End: 107691

Strand: Direct

Name: obgE [H]

Synonym: JJD26997_0100

Alternate gene names: 153952548

Gene position: 106654-107691 (Clockwise)

Preceding gene: 153951563

Following gene: 153950956

Centisome position: 5.78

GC content: 35.65

Gene sequence:

>1038_bases
ATGTTTATTGATAGTGTTAAAATTACTTTAGCTTCTGGTGATGGCGGTAAAGGCGCTGTAAGTTTTCGCCGTGAAAAACA
TGTCCCACTTGGCGGTCCTGATGGAGGAGATGGTGGAAATGGTGGTGATATTATTTTTATATGCGATAATAATACCCACA
CTCTTGTAAATTTCAAAGGCAAAAGAGAATTACGCGCGCAAAATGGTGCTGGTGGAATGGGACGCAATAAAAATGGCAAA
AAAGGTGAAAATTTAGAACTCGTAGTGCCTGAAGGAACGCAAGTTATAGATGCACAAACTAATGAAATTTTACTTGATCT
TACCAAAGAAGGACAAAGAGAGCTTTTTTTAAAAGGTGGAAAAGGCGGACTTGGCAACACTCATTTTAAACATGCCACCA
ATCAACGCCCCGATTACGCACAACCTGGTATAAAAGGAGAAAGTCGCCTAGTTAGACTAGAACTTAAACTTATTGCTGAT
GTAGGGCTTGTAGGCTTTCCAAATGTAGGAAAATCTACTCTTATAAGTGTTGTTTCAAATGCAAAACCTGAAATTGCAAA
TTATGAATTTACCACTCTTACTCCAAAACTTGGACTCGTGGATGTAGATGAGTATAACTCCTTTGTAATGACCGATATTC
CAGGGATTATCCAAGGAGCAAGCGGGGGTAAAGGCTTAGGACTTGCTTTTTTAAAGCACATAGAAAGAACGAGCTTTTTA
CTTTTCGTGCTAGATCCTATGAGGGAAATGCTTTTAAAAGAACAATTTATAGTATTAAGAAAAGAACTTGAAAAATTTTC
CGATGAACTTTTTGGGCGTAAATTTGGCATCATGATTTCAAAAAGTGATAGTGTTAATTTAGGAGAAGAATTTGCCGAGC
AAATTGCTTTGAACATTAATGAGTTAGAAAATTATCTCAAAGAAATAAACAATCCGCAAAGCTTTTTAATCAAAGTCTCA
AGCCTTGAAAAAACAGGACTTAAAGAACTTAAATTCATGCTTTTAGAAGAAATTAAAGCTTTAAGAAATAATAAATAA

Upstream 100 bases:

>100_bases
AGGACGCTTTTTTAGCGTCTTGAAAACTTTAAATTTATAAATTTAACTTCTTTTATTTACTCAAATTTAGCTTTTAAATT
TAAAGTCAAAGGCAATTTAA

Downstream 100 bases:

>100_bases
AAATTTTAATGATCTAGGAGTGTTGTGTATTAAAAATTTTAAATACTTTCTATATTTTTTAAAAAGCAAAAATTAAATAG
CTTGTTTATATGAAATTTTG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MFIDSVKITLASGDGGKGAVSFRREKHVPLGGPDGGDGGNGGDIIFICDNNTHTLVNFKGKRELRAQNGAGGMGRNKNGK
KGENLELVVPEGTQVIDAQTNEILLDLTKEGQRELFLKGGKGGLGNTHFKHATNQRPDYAQPGIKGESRLVRLELKLIAD
VGLVGFPNVGKSTLISVVSNAKPEIANYEFTTLTPKLGLVDVDEYNSFVMTDIPGIIQGASGGKGLGLAFLKHIERTSFL
LFVLDPMREMLLKEQFIVLRKELEKFSDELFGRKFGIMISKSDSVNLGEEFAEQIALNINELENYLKEINNPQSFLIKVS
SLEKTGLKELKFMLLEEIKALRNNK

Sequences:

>Translated_345_residues
MFIDSVKITLASGDGGKGAVSFRREKHVPLGGPDGGDGGNGGDIIFICDNNTHTLVNFKGKRELRAQNGAGGMGRNKNGK
KGENLELVVPEGTQVIDAQTNEILLDLTKEGQRELFLKGGKGGLGNTHFKHATNQRPDYAQPGIKGESRLVRLELKLIAD
VGLVGFPNVGKSTLISVVSNAKPEIANYEFTTLTPKLGLVDVDEYNSFVMTDIPGIIQGASGGKGLGLAFLKHIERTSFL
LFVLDPMREMLLKEQFIVLRKELEKFSDELFGRKFGIMISKSDSVNLGEEFAEQIALNINELENYLKEINNPQSFLIKVS
SLEKTGLKELKFMLLEEIKALRNNK
>Mature_345_residues
MFIDSVKITLASGDGGKGAVSFRREKHVPLGGPDGGDGGNGGDIIFICDNNTHTLVNFKGKRELRAQNGAGGMGRNKNGK
KGENLELVVPEGTQVIDAQTNEILLDLTKEGQRELFLKGGKGGLGNTHFKHATNQRPDYAQPGIKGESRLVRLELKLIAD
VGLVGFPNVGKSTLISVVSNAKPEIANYEFTTLTPKLGLVDVDEYNSFVMTDIPGIIQGASGGKGLGLAFLKHIERTSFL
LFVLDPMREMLLKEQFIVLRKELEKFSDELFGRKFGIMISKSDSVNLGEEFAEQIALNINELENYLKEINNPQSFLIKVS
SLEKTGLKELKFMLLEEIKALRNNK

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI111955139, Length=326, Percent_Identity=36.1963190184049, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI24308117, Length=305, Percent_Identity=38.6885245901639, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI111955063, Length=218, Percent_Identity=34.8623853211009, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI4557537, Length=171, Percent_Identity=32.7485380116959, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=37.7952755905512, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1789574, Length=338, Percent_Identity=43.7869822485207, Blast_Score=231, Evalue=7e-62,
Organism=Caenorhabditis elegans, GI17508313, Length=336, Percent_Identity=37.202380952381, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=311, Percent_Identity=29.903536977492, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI71981008, Length=106, Percent_Identity=41.5094339622642, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=110, Percent_Identity=41.8181818181818, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=122, Percent_Identity=50, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6321612, Length=143, Percent_Identity=34.965034965035, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6319281, Length=109, Percent_Identity=43.1192660550459, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129375, Length=285, Percent_Identity=38.9473684210526, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24585318, Length=283, Percent_Identity=36.3957597173145, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21356473, Length=119, Percent_Identity=39.4957983193277, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17981711, Length=128, Percent_Identity=40.625, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 37805; Mature: 37805

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDSVKITLASGDGGKGAVSFRREKHVPLGGPDGGDGGNGGDIIFICDNNTHTLVNFKG
CCCCEEEEEEEECCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECC
KRELRAQNGAGGMGRNKNGKKGENLELVVPEGTQVIDAQTNEILLDLTKEGQRELFLKGG
CHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCEEEEEECCCCCEEEEEECC
KGGLGNTHFKHATNQRPDYAQPGIKGESRLVRLELKLIADVGLVGFPNVGKSTLISVVSN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHC
AKPEIANYEFTTLTPKLGLVDVDEYNSFVMTDIPGIIQGASGGKGLGLAFLKHIERTSFL
CCCCCCCEEEEEECCCCCEEEHHCCCCEEEECCCHHEECCCCCCCHHHHHHHHHHHHEEE
LFVLDPMREMLLKEQFIVLRKELEKFSDELFGRKFGIMISKSDSVNLGEEFAEQIALNIN
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCHH
ELENYLKEINNPQSFLIKVSSLEKTGLKELKFMLLEEIKALRNNK
HHHHHHHHCCCCHHEEEEEEHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFIDSVKITLASGDGGKGAVSFRREKHVPLGGPDGGDGGNGGDIIFICDNNTHTLVNFKG
CCCCEEEEEEEECCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECC
KRELRAQNGAGGMGRNKNGKKGENLELVVPEGTQVIDAQTNEILLDLTKEGQRELFLKGG
CHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCEEEEEECCCCCEEEEEECC
KGGLGNTHFKHATNQRPDYAQPGIKGESRLVRLELKLIADVGLVGFPNVGKSTLISVVSN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHC
AKPEIANYEFTTLTPKLGLVDVDEYNSFVMTDIPGIIQGASGGKGLGLAFLKHIERTSFL
CCCCCCCEEEEEECCCCCEEEHHCCCCEEEECCCHHEECCCCCCCHHHHHHHHHHHHEEE
LFVLDPMREMLLKEQFIVLRKELEKFSDELFGRKFGIMISKSDSVNLGEEFAEQIALNIN
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCHH
ELENYLKEINNPQSFLIKVSSLEKTGLKELKFMLLEEIKALRNNK
HHHHHHHHCCCCHHEEEEEEHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA