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The map label for this gene is fmt [H]

Identifier: 153950956

GI number: 153950956

Start: 108654

End: 109571

Strand: Direct

Name: fmt [H]

Synonym: JJD26997_0105

Alternate gene names: 153950956

Gene position: 108654-109571 (Clockwise)

Preceding gene: 153952548

Following gene: 153951936

Centisome position: 5.89

GC content: 33.01

Gene sequence:

>918_bases
ATGAAAAAAATTATTTTTATGGGTACTCCATCTTACGCAACTTGTATTTTAAAAGCACTAGTAGAAAATGAAAATTTTAA
ACTCGTAGCACTTTTTACCCAGCCTGATAAAGCCGTAGGTAGAAAGCAAATTTTAACTCCAAGTGATACTAAAGCTTTTT
TAAGTCAAAATTATCCTAGTATTCCTATTTTTACTCCAAGCTCTTTAAAAGATGAAAATATTATGAGACAGATTAAGGAT
TTAAATCCTGATTTTATAGTGGTTGCTGCCTATGGAAAAATTTTGCCTAAAGCCATTTTGGATTTGGCGCCTTGTGTGAA
TTTGCACGCTTCTTTACTTCCAAAATACCGTGGTGCCAGTCCGATCCAAAGTGCGATTTTAAATAAGGATGAAAAAAGTG
GAGTTTGCACCATGCTCATGGAAGAAGGGCTTGACACAGGTGCTATACTTGAAAGCTTAGAATGTGATATAAAAGATAAA
AATTCAAGTGAAGTTTTTGAACTTTTAGCAAATTTAGCCGCTAAGCTCATCCTCTCTACTCTTTTAAATTTCGATAAAAT
AACCCCTAAAAAACAAGAGGAAAGTCTAGCAACGCTTTGTAGAAAAATCAAAAAAGAAGATGGGCTTATAAATTTGCAAA
ATGCAAGAGAACTTTATCAAAAATATCTAGCTTTTACCCCTTGGCCTGGAGTTTTCTTGGAAAATGGACTTAAATTCTTA
GAACTTGAACTCGTGGATGAATTAAAACAAAATGCTAAGATGGGTGAAATTTTAGAATTAGAAAAAGAAAGTTTTTTGCT
TGCTTGCAAACAAGGAGTTTTGCGTATTAAAAAACTTCAAGAAAGTGGAAAAAAAGCTCTTGACGGCAGGACTTATTTAA
ATGGAAAAAGGCTTAAAAGTGAAGATAGTTTGTGTTGA

Upstream 100 bases:

>100_bases
AAATAGGTGGAACTTTGTTTGAGTGATATAATTTATTAAATTCTCTTTTAAAATCAAATAAGTTATAATTAAAACTTTTA
ATTTCACACAAAGCGAAAAA

Downstream 100 bases:

>100_bases
AAGTATAGACTCGACTCATCTTTTTTTATGTGAGCAAATACGCAATGGAAAGATTGATGGAAATTTTGCTATTTATGCTT
TAGAACAAACAAATGGAGTT

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKKIIFMGTPSYATCILKALVENENFKLVALFTQPDKAVGRKQILTPSDTKAFLSQNYPSIPIFTPSSLKDENIMRQIKD
LNPDFIVVAAYGKILPKAILDLAPCVNLHASLLPKYRGASPIQSAILNKDEKSGVCTMLMEEGLDTGAILESLECDIKDK
NSSEVFELLANLAAKLILSTLLNFDKITPKKQEESLATLCRKIKKEDGLINLQNARELYQKYLAFTPWPGVFLENGLKFL
ELELVDELKQNAKMGEILELEKESFLLACKQGVLRIKKLQESGKKALDGRTYLNGKRLKSEDSLC

Sequences:

>Translated_305_residues
MKKIIFMGTPSYATCILKALVENENFKLVALFTQPDKAVGRKQILTPSDTKAFLSQNYPSIPIFTPSSLKDENIMRQIKD
LNPDFIVVAAYGKILPKAILDLAPCVNLHASLLPKYRGASPIQSAILNKDEKSGVCTMLMEEGLDTGAILESLECDIKDK
NSSEVFELLANLAAKLILSTLLNFDKITPKKQEESLATLCRKIKKEDGLINLQNARELYQKYLAFTPWPGVFLENGLKFL
ELELVDELKQNAKMGEILELEKESFLLACKQGVLRIKKLQESGKKALDGRTYLNGKRLKSEDSLC
>Mature_305_residues
MKKIIFMGTPSYATCILKALVENENFKLVALFTQPDKAVGRKQILTPSDTKAFLSQNYPSIPIFTPSSLKDENIMRQIKD
LNPDFIVVAAYGKILPKAILDLAPCVNLHASLLPKYRGASPIQSAILNKDEKSGVCTMLMEEGLDTGAILESLECDIKDK
NSSEVFELLANLAAKLILSTLLNFDKITPKKQEESLATLCRKIKKEDGLINLQNARELYQKYLAFTPWPGVFLENGLKFL
ELELVDELKQNAKMGEILELEKESFLLACKQGVLRIKKLQESGKKALDGRTYLNGKRLKSEDSLC

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI164663775, Length=232, Percent_Identity=25.4310344827586, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789683, Length=304, Percent_Identity=37.171052631579, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1788589, Length=292, Percent_Identity=28.0821917808219, Blast_Score=86, Evalue=4e-18,
Organism=Drosophila melanogaster, GI45550868, Length=308, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571984, Length=225, Percent_Identity=31.1111111111111, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24585660, Length=167, Percent_Identity=25.1497005988024, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 34087; Mature: 34087

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIFMGTPSYATCILKALVENENFKLVALFTQPDKAVGRKQILTPSDTKAFLSQNYPS
CCEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHCCCCCCCCCCHHHHHHCCCCC
IPIFTPSSLKDENIMRQIKDLNPDFIVVAAYGKILPKAILDLAPCVNLHASLLPKYRGAS
CEEECCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PIQSAILNKDEKSGVCTMLMEEGLDTGAILESLECDIKDKNSSEVFELLANLAAKLILST
HHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LLNFDKITPKKQEESLATLCRKIKKEDGLINLQNARELYQKYLAFTPWPGVFLENGLKFL
HHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCHHHHCCHHHH
ELELVDELKQNAKMGEILELEKESFLLACKQGVLRIKKLQESGKKALDGRTYLNGKRLKS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EDSLC
CCCCC
>Mature Secondary Structure
MKKIIFMGTPSYATCILKALVENENFKLVALFTQPDKAVGRKQILTPSDTKAFLSQNYPS
CCEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHCCCCCCCCCCHHHHHHCCCCC
IPIFTPSSLKDENIMRQIKDLNPDFIVVAAYGKILPKAILDLAPCVNLHASLLPKYRGAS
CEEECCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PIQSAILNKDEKSGVCTMLMEEGLDTGAILESLECDIKDKNSSEVFELLANLAAKLILST
HHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LLNFDKITPKKQEESLATLCRKIKKEDGLINLQNARELYQKYLAFTPWPGVFLENGLKFL
HHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCHHHHCCHHHH
ELELVDELKQNAKMGEILELEKESFLLACKQGVLRIKKLQESGKKALDGRTYLNGKRLKS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EDSLC
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA