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The map label for this gene is chuA [H]

Identifier: 153952500

GI number: 153952500

Start: 1737440

End: 1739512

Strand: Direct

Name: chuA [H]

Synonym: JJD26997_1968

Alternate gene names: 153952500

Gene position: 1737440-1739512 (Clockwise)

Preceding gene: 153952433

Following gene: 153951720

Centisome position: 94.16

GC content: 30.92

Gene sequence:

>2073_bases
TTGCACCCAAATAAAAAGCTTTATAAGTTATCTTTATTTGCATTATTACTAATAACTAATTTAAATGCACAAGAATCAAA
TGAAGCTATCAATCTACAAAAAGTTGTTGTTAGTGCAACAGGTTTTGAACAAGATGCAGACTCAAATTTACGCAATGTAA
TCAGCATTGAAGGCAAAGATCTGCAAAATAAAGGTTATGTTTCCTTAGAACAAGCCTTAGAAAGAATTTCGGGCATTAGT
TTTGTAAATTTTGGACTTGGACGCAATATAGACATGCGTGGACAAGGAAATAAGTCCAATATAGCTGTAAAAGTTATGAT
CGATGGGCGTACTATTAATGTTCTTGATAATTCCCATGGTGTAACCCCGCTAGATAGTATCAATTTAGATAATGTAGAAC
GCATAGAAATCATACCTGGGGGTGGGTCTGTGCTTTATGGAAGTGGTACTAGAGGGGGTGTGATTAATATCATTACAAAA
AAACAAAAATCAGATGCTTTTGCTATAAATTTAAAAAGCAGTGCTTATGATCATGGTAGATTAGGTGGGAATTTAGGTAT
CAATGGCGCCAAACAAATAAATGAAAATTTAGCTTTTAGCTTTGATATACAAAGTTTTAACCTTGATGGATATCAAGAAG
GTTATAATGAAAAAGGCTATTTTATCAACACAAAAACCTATATTGATATCAATGATAATAGCGATTTAACTTTGGGTTAT
AATTATTTTAAAAGCAAAAATACTAGCAGTGGTTATCTAACAAAAGCACAAGCTCAAAGCAATCCAACTCAAAAAGGTAA
GAGTGATAATATCACACAAATCAATCGCCCTGAAATTTCTTTGGATTATCATTACTATTTTGATGATATATGGCAATTTA
ACCTAGAAGCTTTTTGGCAAAATCAAAAAATCAATTATCTAAAATCTGTAGGAAATGGCTTTGAAGACACACTTACAGGG
ATAAGTTTAAAAAACAAGCTAAATTATGCAAATAATTCTTATTTTATTTTTGGTTACGAATTTGCAAACCATGATGCAAA
AAGAAAGAGTTTGAGGTATTATAGTGTTCCGAATGTCATAAATTATCACAGGATGACAACTTTAATGGATATGACTAAGC
AAAGCCATTCTATTTTCGCTCTTGATTCTCATAATTTTAATGAATTTTTTACTTTATCTGGTGGAGTTAGATATGAATTT
AGCACTTATAATACCCATAGATCTTATAGAAATGAAATGAGTATGAACAAAAAACCCCCATCAGACACAACAACCCTTTT
TGATACGAATAAAAACACCAATAATTTTGCTTTTGAAATCACTCCTAACTTTAAATACTCTGACACAGGTAATCTTTATC
TTAAATACGAAAGAGGTTTTGTTTCTCCTACACCTGCTCAGTTTGTCAATAAGGATCAAGCAACTCAAACGTATTATTCT
GTAAATTTAAATCCTGAGATCTTTGATACCTTTGAACTAGGAATTGATGATTTTTGGTGGGATTTTTACGGCTTTAATCT
AACTTTATTTTACACCCTAAGCAAAGATGAAATTTCTTATCGTGGAAACCCTCATGCAAGAGGTGGAGGATTTTGGCAAT
ATTATAATATAGATCAAACTCGCCGTTTAGGAGTAGAATTAAGCCTGAGTCAAAATTTTTTAGATGATGATTTAATCTTT
AGAGAAAGTCTAACTTATCTTGATGCTAAAATTTCTAAAGGTGTTAATGACGGCATGAGAATTCCTTATGTTTCAAAAAT
CAAAGTCACAGCTGGGCTTGAATACGCTTGGAATAAAAATTTCTCAAATTTTGTTGATTTAACCTATTTTTCTAGAGCAA
AAGATGGTGGAACTATAAATGAAAATACAGGAAAAATGTCTAAAAATTCTTGGATAAGGGATTATTTTTTAACAGATATT
GGCATGAAATATAATTATAAAAAATTACAAATTTTAGCAGGAATTCGCAATCTTTTTGATAAAAGATACTACACCTACCA
AGACAGTATAAATGATCAATACCTAGCTGGAAATGGTAGAAACTACTATGTTGAATTTAAATACGCGTTCTAA

Upstream 100 bases:

>100_bases
TAGCAAAAATTTATACTAAATTAAGTTAATAAAGGATAAATTTCGTTCTAAATTATTATGATATAAATTATCATTATTTA
TTTTATTTAAGGAGTAAAAT

Downstream 100 bases:

>100_bases
AATTTTAGTGATTATAGGGCTTTTAGTAGCTTATATAATCGCTTCTTTTATAGCACTTTGCTTAGGAGATGAAAATCTAA
ACCCAAAAGAACTTTTTTCA

Product: TonB-dependent heme receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MHPNKKLYKLSLFALLLITNLNAQESNEAINLQKVVVSATGFEQDADSNLRNVISIEGKDLQNKGYVSLEQALERISGIS
FVNFGLGRNIDMRGQGNKSNIAVKVMIDGRTINVLDNSHGVTPLDSINLDNVERIEIIPGGGSVLYGSGTRGGVINIITK
KQKSDAFAINLKSSAYDHGRLGGNLGINGAKQINENLAFSFDIQSFNLDGYQEGYNEKGYFINTKTYIDINDNSDLTLGY
NYFKSKNTSSGYLTKAQAQSNPTQKGKSDNITQINRPEISLDYHYYFDDIWQFNLEAFWQNQKINYLKSVGNGFEDTLTG
ISLKNKLNYANNSYFIFGYEFANHDAKRKSLRYYSVPNVINYHRMTTLMDMTKQSHSIFALDSHNFNEFFTLSGGVRYEF
STYNTHRSYRNEMSMNKKPPSDTTTLFDTNKNTNNFAFEITPNFKYSDTGNLYLKYERGFVSPTPAQFVNKDQATQTYYS
VNLNPEIFDTFELGIDDFWWDFYGFNLTLFYTLSKDEISYRGNPHARGGGFWQYYNIDQTRRLGVELSLSQNFLDDDLIF
RESLTYLDAKISKGVNDGMRIPYVSKIKVTAGLEYAWNKNFSNFVDLTYFSRAKDGGTINENTGKMSKNSWIRDYFLTDI
GMKYNYKKLQILAGIRNLFDKRYYTYQDSINDQYLAGNGRNYYVEFKYAF

Sequences:

>Translated_690_residues
MHPNKKLYKLSLFALLLITNLNAQESNEAINLQKVVVSATGFEQDADSNLRNVISIEGKDLQNKGYVSLEQALERISGIS
FVNFGLGRNIDMRGQGNKSNIAVKVMIDGRTINVLDNSHGVTPLDSINLDNVERIEIIPGGGSVLYGSGTRGGVINIITK
KQKSDAFAINLKSSAYDHGRLGGNLGINGAKQINENLAFSFDIQSFNLDGYQEGYNEKGYFINTKTYIDINDNSDLTLGY
NYFKSKNTSSGYLTKAQAQSNPTQKGKSDNITQINRPEISLDYHYYFDDIWQFNLEAFWQNQKINYLKSVGNGFEDTLTG
ISLKNKLNYANNSYFIFGYEFANHDAKRKSLRYYSVPNVINYHRMTTLMDMTKQSHSIFALDSHNFNEFFTLSGGVRYEF
STYNTHRSYRNEMSMNKKPPSDTTTLFDTNKNTNNFAFEITPNFKYSDTGNLYLKYERGFVSPTPAQFVNKDQATQTYYS
VNLNPEIFDTFELGIDDFWWDFYGFNLTLFYTLSKDEISYRGNPHARGGGFWQYYNIDQTRRLGVELSLSQNFLDDDLIF
RESLTYLDAKISKGVNDGMRIPYVSKIKVTAGLEYAWNKNFSNFVDLTYFSRAKDGGTINENTGKMSKNSWIRDYFLTDI
GMKYNYKKLQILAGIRNLFDKRYYTYQDSINDQYLAGNGRNYYVEFKYAF
>Mature_690_residues
MHPNKKLYKLSLFALLLITNLNAQESNEAINLQKVVVSATGFEQDADSNLRNVISIEGKDLQNKGYVSLEQALERISGIS
FVNFGLGRNIDMRGQGNKSNIAVKVMIDGRTINVLDNSHGVTPLDSINLDNVERIEIIPGGGSVLYGSGTRGGVINIITK
KQKSDAFAINLKSSAYDHGRLGGNLGINGAKQINENLAFSFDIQSFNLDGYQEGYNEKGYFINTKTYIDINDNSDLTLGY
NYFKSKNTSSGYLTKAQAQSNPTQKGKSDNITQINRPEISLDYHYYFDDIWQFNLEAFWQNQKINYLKSVGNGFEDTLTG
ISLKNKLNYANNSYFIFGYEFANHDAKRKSLRYYSVPNVINYHRMTTLMDMTKQSHSIFALDSHNFNEFFTLSGGVRYEF
STYNTHRSYRNEMSMNKKPPSDTTTLFDTNKNTNNFAFEITPNFKYSDTGNLYLKYERGFVSPTPAQFVNKDQATQTYYS
VNLNPEIFDTFELGIDDFWWDFYGFNLTLFYTLSKDEISYRGNPHARGGGFWQYYNIDQTRRLGVELSLSQNFLDDDLIF
RESLTYLDAKISKGVNDGMRIPYVSKIKVTAGLEYAWNKNFSNFVDLTYFSRAKDGGTINENTGKMSKNSWIRDYFLTDI
GMKYNYKKLQILAGIRNLFDKRYYTYQDSINDQYLAGNGRNYYVEFKYAF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=132, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790743, Length=700, Percent_Identity=22.5714285714286, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787723, Length=261, Percent_Identity=29.8850574712644, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79106; Mature: 79106

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPNKKLYKLSLFALLLITNLNAQESNEAINLQKVVVSATGFEQDADSNLRNVISIEGKD
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEECCCC
LQNKGYVSLEQALERISGISFVNFGLGRNIDMRGQGNKSNIAVKVMIDGRTINVLDNSHG
CCCCCCEEHHHHHHHHCCCEEEEECCCCCEECCCCCCCCCEEEEEEECCEEEEEEECCCC
VTPLDSINLDNVERIEIIPGGGSVLYGSGTRGGVINIITKKQKSDAFAINLKSSAYDHGR
CCCCCCCCCCCCEEEEEEECCCEEEECCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCC
LGGNLGINGAKQINENLAFSFDIQSFNLDGYQEGYNEKGYFINTKTYIDINDNSDLTLGY
CCCCCCCCCHHHHCCCCEEEEEEEEECCCCHHCCCCCCCEEEEEEEEEEECCCCCEEEEE
NYFKSKNTSSGYLTKAQAQSNPTQKGKSDNITQINRPEISLDYHYYFDDIWQFNLEAFWQ
HHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCEEEEEEEEEECCCEEECEEEEEC
NQKINYLKSVGNGFEDTLTGISLKNKLNYANNSYFIFGYEFANHDAKRKSLRYYSVPNVI
CCCHHHHHHHCCCHHHHHCCEEEECCCCCCCCEEEEEEEEECCCCCHHHCEEEEECCCCH
NYHRMTTLMDMTKQSHSIFALDSHNFNEFFTLSGGVRYEFSTYNTHRSYRNEMSMNKKPP
HHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCEEEEEECCCCHHHHHHHCCCCCCCC
SDTTTLFDTNKNTNNFAFEITPNFKYSDTGNLYLKYERGFVSPTPAQFVNKDQATQTYYS
CCCEEEEECCCCCCCEEEEEECCCEECCCCCEEEEEECCCCCCCHHHHCCCCCCCEEEEE
VNLNPEIFDTFELGIDDFWWDFYGFNLTLFYTLSKDEISYRGNPHARGGGFWQYYNIDQT
EECCCCEEEEEECCCCHHHHEEECCEEEEEEEEECCCEEECCCCCCCCCCEEEEECCCCH
RRLGVELSLSQNFLDDDLIFRESLTYLDAKISKGVNDGMRIPYVSKIKVTAGLEYAWNKN
HEECEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECEEEEECCC
FSNFVDLTYFSRAKDGGTINENTGKMSKNSWIRDYFLTDIGMKYNYKKLQILAGIRNLFD
CCCEEEEEEEECCCCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
KRYYTYQDSINDQYLAGNGRNYYVEFKYAF
CCEEEEECCCCCEEEECCCCEEEEEEEEEC
>Mature Secondary Structure
MHPNKKLYKLSLFALLLITNLNAQESNEAINLQKVVVSATGFEQDADSNLRNVISIEGKD
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEECCCC
LQNKGYVSLEQALERISGISFVNFGLGRNIDMRGQGNKSNIAVKVMIDGRTINVLDNSHG
CCCCCCEEHHHHHHHHCCCEEEEECCCCCEECCCCCCCCCEEEEEEECCEEEEEEECCCC
VTPLDSINLDNVERIEIIPGGGSVLYGSGTRGGVINIITKKQKSDAFAINLKSSAYDHGR
CCCCCCCCCCCCEEEEEEECCCEEEECCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCC
LGGNLGINGAKQINENLAFSFDIQSFNLDGYQEGYNEKGYFINTKTYIDINDNSDLTLGY
CCCCCCCCCHHHHCCCCEEEEEEEEECCCCHHCCCCCCCEEEEEEEEEEECCCCCEEEEE
NYFKSKNTSSGYLTKAQAQSNPTQKGKSDNITQINRPEISLDYHYYFDDIWQFNLEAFWQ
HHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCEEEEEEEEEECCCEEECEEEEEC
NQKINYLKSVGNGFEDTLTGISLKNKLNYANNSYFIFGYEFANHDAKRKSLRYYSVPNVI
CCCHHHHHHHCCCHHHHHCCEEEECCCCCCCCEEEEEEEEECCCCCHHHCEEEEECCCCH
NYHRMTTLMDMTKQSHSIFALDSHNFNEFFTLSGGVRYEFSTYNTHRSYRNEMSMNKKPP
HHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCEEEEEECCCCHHHHHHHCCCCCCCC
SDTTTLFDTNKNTNNFAFEITPNFKYSDTGNLYLKYERGFVSPTPAQFVNKDQATQTYYS
CCCEEEEECCCCCCCEEEEEECCCEECCCCCEEEEEECCCCCCCHHHHCCCCCCCEEEEE
VNLNPEIFDTFELGIDDFWWDFYGFNLTLFYTLSKDEISYRGNPHARGGGFWQYYNIDQT
EECCCCEEEEEECCCCHHHHEEECCEEEEEEEEECCCEEECCCCCCCCCCEEEEECCCCH
RRLGVELSLSQNFLDDDLIFRESLTYLDAKISKGVNDGMRIPYVSKIKVTAGLEYAWNKN
HEECEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECEEEEECCC
FSNFVDLTYFSRAKDGGTINENTGKMSKNSWIRDYFLTDIGMKYNYKKLQILAGIRNLFD
CCCEEEEEEEECCCCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
KRYYTYQDSINDQYLAGNGRNYYVEFKYAF
CCEEEEECCCCCEEEECCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA