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The map label for this gene is hflC [C]

Identifier: 153952483

GI number: 153952483

Start: 1508579

End: 1509667

Strand: Direct

Name: hflC [C]

Synonym: JJD26997_1708

Alternate gene names: 153952483

Gene position: 1508579-1509667 (Clockwise)

Preceding gene: 153951913

Following gene: 153952134

Centisome position: 81.76

GC content: 33.52

Gene sequence:

>1089_bases
ATGCCAGCTGATTTGAATGATTATTTCAACAAAAAAAATGGAAATTCTAACAATAACGGAAACAACAACCGTCAAAATTT
CAATTTCAAAGCACCAGAATTTAATTTTAAAGGTTTTGGTAAATTCTCTCCGTTTGTTTATGGGGTGATTATTATTGTTT
TATTTTTAATCGTTGCAAAACCTTTTATGGTTATAAATTCTGGGGAAATGGGGATTAAATCAACAACAGGTAAATATGAC
CCAAATCCATTAGAACCAGGACTTCACTTTTTCTTACCTTTTGTACAAAAAATAACCATAATCGATACTAGAGTAAGACA
AATCAACTATGCTTCTATAGAGGGAAGTAATGAAAATTTATCTTTAGGTTCAGGTGTTATTAATAAAAATAGCATTTCTG
TGCTTGACTCTCGTGGATTGCCTGTATCTATTGATGTTACAGTACAATACCGTTTAAATCCTTTGCAAGTTCCTCAAACC
ATAGCTACTTGGAGCTTAAATTGGGAAAATAAAATTATCGATCCAGTTGTTCGTGATGTAGTGCGAAGTGTTGTAGGAAA
ATATACAGCCGAAGAACTTCCTACTAATCGTAATACAATAGCCACTCAAATAGAAGAAGGTATAAGAAAAACTATAGAAG
CTCAACCAAATGAACCTGTAGAACTTCGCGCTGTACAACTTAGAGAAATTATTTTACCTTCAAAAGTAAAAGAACAAATC
GAACGGGTGCAAATTGCAAAACAAGAAGCTGAAAGAACCAAATATGAAGTAGAAAGAGCTAATCAAGAAGCCTTAAAAAA
AGCTGCCTTAGCTGAAGGGGAAGCAAACGCAACCATAATCAGCGCCAAAGGTAAAGCTATGGCTGTTAAAATAGAAGCAG
ATGCACAAGCTTATTCTAATAAAGAAATCGCAAACAGCTTAAACACTCCTTTGCTAAATTTAAAACAAATTGAAACTCAA
AAAGAATTTAACGAAGCTTTAAAAGTCAATCAAGATGCTAAAATTTTCTTAACTCCAGGTGGAGCAGTGCCAAACATTTG
GGTCGATACTAAAGATGCTAAAAAGCAAAGTTCTGCCAACATGAACTAA

Upstream 100 bases:

>100_bases
TCTGTAACCAAAAAACTTCAAGATGCTTATTTTGATGTAGTTTATGGACGCAATGAAAAATACGCATCTATGCTAACTTA
TATTTAAAAAAAGGAAATAA

Downstream 100 bases:

>100_bases
AGGTTACGCAAGTGGAGAAACTAAGAGAAATCGTGCTTTTTTACACTACTCATTTATATTTAGTAGATTATATGCTGATT
TTATTAGTTTTTTTTCTCTT

Product: SPFH domain-containing protein

Products: NA

Alternate protein names: SPFH Domain-Containing Protein; Spfh Domain Band 7 Family Protein; SPFH Domain Band 7 Family Protein; Cation-Transporting ATPase/ Band 7 Family Protein; Band 7 Family Protein; Spfh Domain Protein; Cation-Transporting ATPase P-Type; Tomatin/Podocin/Band 7/Nephrosis.2/SPFH Family Protein

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MPADLNDYFNKKNGNSNNNGNNNRQNFNFKAPEFNFKGFGKFSPFVYGVIIIVLFLIVAKPFMVINSGEMGIKSTTGKYD
PNPLEPGLHFFLPFVQKITIIDTRVRQINYASIEGSNENLSLGSGVINKNSISVLDSRGLPVSIDVTVQYRLNPLQVPQT
IATWSLNWENKIIDPVVRDVVRSVVGKYTAEELPTNRNTIATQIEEGIRKTIEAQPNEPVELRAVQLREIILPSKVKEQI
ERVQIAKQEAERTKYEVERANQEALKKAALAEGEANATIISAKGKAMAVKIEADAQAYSNKEIANSLNTPLLNLKQIETQ
KEFNEALKVNQDAKIFLTPGGAVPNIWVDTKDAKKQSSANMN

Sequences:

>Translated_362_residues
MPADLNDYFNKKNGNSNNNGNNNRQNFNFKAPEFNFKGFGKFSPFVYGVIIIVLFLIVAKPFMVINSGEMGIKSTTGKYD
PNPLEPGLHFFLPFVQKITIIDTRVRQINYASIEGSNENLSLGSGVINKNSISVLDSRGLPVSIDVTVQYRLNPLQVPQT
IATWSLNWENKIIDPVVRDVVRSVVGKYTAEELPTNRNTIATQIEEGIRKTIEAQPNEPVELRAVQLREIILPSKVKEQI
ERVQIAKQEAERTKYEVERANQEALKKAALAEGEANATIISAKGKAMAVKIEADAQAYSNKEIANSLNTPLLNLKQIETQ
KEFNEALKVNQDAKIFLTPGGAVPNIWVDTKDAKKQSSANMN
>Mature_361_residues
PADLNDYFNKKNGNSNNNGNNNRQNFNFKAPEFNFKGFGKFSPFVYGVIIIVLFLIVAKPFMVINSGEMGIKSTTGKYDP
NPLEPGLHFFLPFVQKITIIDTRVRQINYASIEGSNENLSLGSGVINKNSISVLDSRGLPVSIDVTVQYRLNPLQVPQTI
ATWSLNWENKIIDPVVRDVVRSVVGKYTAEELPTNRNTIATQIEEGIRKTIEAQPNEPVELRAVQLREIILPSKVKEQIE
RVQIAKQEAERTKYEVERANQEALKKAALAEGEANATIISAKGKAMAVKIEADAQAYSNKEIANSLNTPLLNLKQIETQK
EFNEALKVNQDAKIFLTPGGAVPNIWVDTKDAKKQSSANMN

Specific function: Hflc And Hflk Govern The Stability Of Phage Lambda Cii Protein And Have Been Proposed To Encode Or Regulate A Cii- Specific Protease. [C]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4505773, Length=258, Percent_Identity=26.7441860465116, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI6005854, Length=195, Percent_Identity=29.7435897435897, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI221307584, Length=195, Percent_Identity=29.7435897435897, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193205005, Length=214, Percent_Identity=31.3084112149533, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509869, Length=188, Percent_Identity=23.936170212766, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321571, Length=204, Percent_Identity=29.9019607843137, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24585145, Length=202, Percent_Identity=26.2376237623762, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24585147, Length=202, Percent_Identity=26.2376237623762, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161077240, Length=219, Percent_Identity=28.310502283105, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161077244, Length=219, Percent_Identity=28.310502283105, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161077238, Length=219, Percent_Identity=28.310502283105, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161077236, Length=219, Percent_Identity=28.310502283105, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161077234, Length=219, Percent_Identity=28.310502283105, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161077242, Length=219, Percent_Identity=28.310502283105, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40288; Mature: 40157

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPADLNDYFNKKNGNSNNNGNNNRQNFNFKAPEFNFKGFGKFSPFVYGVIIIVLFLIVAK
CCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PFMVINSGEMGIKSTTGKYDPNPLEPGLHFFLPFVQKITIIDTRVRQINYASIEGSNENL
CEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCC
SLGSGVINKNSISVLDSRGLPVSIDVTVQYRLNPLQVPQTIATWSLNWENKIIDPVVRDV
CCCCCCCCCCCEEEEECCCCEEEEEEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHH
VRSVVGKYTAEELPTNRNTIATQIEEGIRKTIEAQPNEPVELRAVQLREIILPSKVKEQI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHH
ERVQIAKQEAERTKYEVERANQEALKKAALAEGEANATIISAKGKAMAVKIEADAQAYSN
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCHHHHCC
KEIANSLNTPLLNLKQIETQKEFNEALKVNQDAKIFLTPGGAVPNIWVDTKDAKKQSSAN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCHHHHHHCCC
MN
CC
>Mature Secondary Structure 
PADLNDYFNKKNGNSNNNGNNNRQNFNFKAPEFNFKGFGKFSPFVYGVIIIVLFLIVAK
CCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PFMVINSGEMGIKSTTGKYDPNPLEPGLHFFLPFVQKITIIDTRVRQINYASIEGSNENL
CEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCC
SLGSGVINKNSISVLDSRGLPVSIDVTVQYRLNPLQVPQTIATWSLNWENKIIDPVVRDV
CCCCCCCCCCCEEEEECCCCEEEEEEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHH
VRSVVGKYTAEELPTNRNTIATQIEEGIRKTIEAQPNEPVELRAVQLREIILPSKVKEQI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHH
ERVQIAKQEAERTKYEVERANQEALKKAALAEGEANATIISAKGKAMAVKIEADAQAYSN
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCHHHHCC
KEIANSLNTPLLNLKQIETQKEFNEALKVNQDAKIFLTPGGAVPNIWVDTKDAKKQSSAN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCHHHHHHCCC
MN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA