Click here to switch to the map view.

The map label for this gene is ilvE [H]

Identifier: 153951913

GI number: 153951913

Start: 1507651

End: 1508565

Strand: Direct

Name: ilvE [H]

Synonym: JJD26997_1707

Alternate gene names: 153951913

Gene position: 1507651-1508565 (Clockwise)

Preceding gene: 153951718

Following gene: 153952483

Centisome position: 81.71

GC content: 37.38

Gene sequence:

>915_bases
ATGATACACGTAGAAAAAATTTGGATGGATGGAAAATTAGTTGATTTTAAAGATGCAACTTTGCACTTTTTAACCCATTC
TTTGCATTATGGCAATGCTGTTTTTGAAGGAACTAGAGCCTATAAAACAGATAAAGGCTTAGCGATTTTCAGACTTGAAG
AGCACACAAAAAGACTGCTTGAAAGTGCCAAAATCACGCTTTTAAATTGTCCATTCTCTCAAAAAGAGCTTGAAAATGCT
CAAATCGAACTTTTAAGGGCAAATGCCTTTAAAGAAAATACTTACATACGCCCCTTAATCTTCTTAGGCGATGGCGTTAT
GGGGCTTTATCATATCAAAGCCCCTGTGCGTGTAGGCATAGCTGCTTGGGAATGGGGGGCTTATCTTGGCGAGGAGGGAC
TTGAAAAGGGTATTAAGGTCAAAATTTCCTCTTTTGCTAGAAATAGCGTCAAATCTTGCATGGGTAAGGCTAAAGCAAGT
GCGAATTATCTCAATTCTCAAATTGCCAAATTTGAAGCTATTGAAGCAGGCTATGAAGAAGCTTTGATGCTTGATGAAGA
AGGTTTTATCGCAGAGGGAACGGGAGAGTGCTTTTTTATCGTAAAAGATGGAGTTTTAATCACTCCTCCTAATGACTTTT
CCCTAAAAAGCATTACTCAAGATACAGTACTTAGAATCGCTCATGATCTTGGTACCACTGTGCTTCGTCAAAGAATTTCA
AGAGATGAAGTTTATACTGCCGATGAAGCATTTTTTACCGGAACAGCCGCTGAAATCACTCCTATTAACAATATTGATGC
AAGAACAATAGGAAATGGTTTAAGAGGATCTGTAACCAAAAAACTTCAAGATGCTTATTTTGATGTAGTTTATGGACGCA
ATGAAAAATACGCATCTATGCTAACTTATATTTAA

Upstream 100 bases:

>100_bases
TCTTGAAACATTTATGAAAAATTTACTTTATTTTTATCAAAAAGCTAATTGTTAGCCTATTTTTGCTACAATCACGCTTT
ATTAAAGGAAAAGAGGTGAT

Downstream 100 bases:

>100_bases
AAAAAGGAAATAAATGCCAGCTGATTTGAATGATTATTTCAACAAAAAAAATGGAAATTCTAACAATAACGGAAACAACA
ACCGTCAAAATTTCAATTTC

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MIHVEKIWMDGKLVDFKDATLHFLTHSLHYGNAVFEGTRAYKTDKGLAIFRLEEHTKRLLESAKITLLNCPFSQKELENA
QIELLRANAFKENTYIRPLIFLGDGVMGLYHIKAPVRVGIAAWEWGAYLGEEGLEKGIKVKISSFARNSVKSCMGKAKAS
ANYLNSQIAKFEAIEAGYEEALMLDEEGFIAEGTGECFFIVKDGVLITPPNDFSLKSITQDTVLRIAHDLGTTVLRQRIS
RDEVYTADEAFFTGTAAEITPINNIDARTIGNGLRGSVTKKLQDAYFDVVYGRNEKYASMLTYI

Sequences:

>Translated_304_residues
MIHVEKIWMDGKLVDFKDATLHFLTHSLHYGNAVFEGTRAYKTDKGLAIFRLEEHTKRLLESAKITLLNCPFSQKELENA
QIELLRANAFKENTYIRPLIFLGDGVMGLYHIKAPVRVGIAAWEWGAYLGEEGLEKGIKVKISSFARNSVKSCMGKAKAS
ANYLNSQIAKFEAIEAGYEEALMLDEEGFIAEGTGECFFIVKDGVLITPPNDFSLKSITQDTVLRIAHDLGTTVLRQRIS
RDEVYTADEAFFTGTAAEITPINNIDARTIGNGLRGSVTKKLQDAYFDVVYGRNEKYASMLTYI
>Mature_304_residues
MIHVEKIWMDGKLVDFKDATLHFLTHSLHYGNAVFEGTRAYKTDKGLAIFRLEEHTKRLLESAKITLLNCPFSQKELENA
QIELLRANAFKENTYIRPLIFLGDGVMGLYHIKAPVRVGIAAWEWGAYLGEEGLEKGIKVKISSFARNSVKSCMGKAKAS
ANYLNSQIAKFEAIEAGYEEALMLDEEGFIAEGTGECFFIVKDGVLITPPNDFSLKSITQDTVLRIAHDLGTTVLRQRIS
RDEVYTADEAFFTGTAAEITPINNIDARTIGNGLRGSVTKKLQDAYFDVVYGRNEKYASMLTYI

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=293, Percent_Identity=26.2798634812287, Blast_Score=78, Evalue=8e-15,
Organism=Escherichia coli, GI48994963, Length=294, Percent_Identity=44.8979591836735, Blast_Score=249, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6322002, Length=331, Percent_Identity=26.2839879154079, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 33997; Mature: 33997

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHVEKIWMDGKLVDFKDATLHFLTHSLHYGNAVFEGTRAYKTDKGLAIFRLEEHTKRLL
CEEEEEEEECCEEECCCHHHHHHHHHHHHCCCCEECCCCCEECCCCEEEEEEHHHHHHHH
ESAKITLLNCPFSQKELENAQIELLRANAFKENTYIRPLIFLGDGVMGLYHIKAPVRVGI
HCCCEEEEECCCCHHHHCCHHEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCEEEE
AAWEWGAYLGEEGLEKGIKVKISSFARNSVKSCMGKAKASANYLNSQIAKFEAIEAGYEE
EEEHHHHHHCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ALMLDEEGFIAEGTGECFFIVKDGVLITPPNDFSLKSITQDTVLRIAHDLGTTVLRQRIS
EEEECCCCCEECCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RDEVYTADEAFFTGTAAEITPINNIDARTIGNGLRGSVTKKLQDAYFDVVYGRNEKYASM
CCCEEECCCCEEECCCEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHEEECCCCHHHHH
LTYI
HHCC
>Mature Secondary Structure
MIHVEKIWMDGKLVDFKDATLHFLTHSLHYGNAVFEGTRAYKTDKGLAIFRLEEHTKRLL
CEEEEEEEECCEEECCCHHHHHHHHHHHHCCCCEECCCCCEECCCCEEEEEEHHHHHHHH
ESAKITLLNCPFSQKELENAQIELLRANAFKENTYIRPLIFLGDGVMGLYHIKAPVRVGI
HCCCEEEEECCCCHHHHCCHHEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCEEEE
AAWEWGAYLGEEGLEKGIKVKISSFARNSVKSCMGKAKASANYLNSQIAKFEAIEAGYEE
EEEHHHHHHCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ALMLDEEGFIAEGTGECFFIVKDGVLITPPNDFSLKSITQDTVLRIAHDLGTTVLRQRIS
EEEECCCCCEECCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RDEVYTADEAFFTGTAAEITPINNIDARTIGNGLRGSVTKKLQDAYFDVVYGRNEKYASM
CCCEEECCCCEEECCCEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHEEECCCCHHHHH
LTYI
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]