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The map label for this gene is phoR [H]

Identifier: 153952369

GI number: 153952369

Start: 820998

End: 822287

Strand: Direct

Name: phoR [H]

Synonym: JJD26997_0924

Alternate gene names: 153952369

Gene position: 820998-822287 (Clockwise)

Preceding gene: 153951656

Following gene: 153951421

Centisome position: 44.5

GC content: 24.5

Gene sequence:

>1290_bases
ATGCTAAAAACTAAAAATATTTTTATAGTTTTTTTTGTTGTATTGGCTTTGATTTTTGGGTTTATTTTTTATACTTTTAC
TAACTCTTATCTTAATTTTTTGCTTATAAAACAATATAAGCAAAAAATCAAAAGCCTTGATGATGTTTTAAAATTTTCTC
TCTTAGAGCATTTAAATAATGCTAATATCAAGGATTTTGCTAAAGATACTAGGGCTGATTTTATTATCCTAAACAATAAT
ATGAAAATAAGTTCTGTAAAAAATCCTGATTTTTTTTCTAATCTTAAAGAAGGAGAAATTTTAAATTTCAATTCAAAAAA
AATTCTCACTAAAAGCTTTATTTACAAAGGGTATAAATATGTTATTATTGTTTATCCTCGTTTTTTAGATTTAGAACTTT
TTTGGACAAAAATAACAATCGGTTTTGGAGTATGCTTGCTGTTTGTTTTTATTTTAATGTTGTTGTTGGGTAGAAGAATA
GAGAAAAATTTTAATAAAATTTTGGATTTTTTGGATTCTATAGGCAATCATAAAGTTGTTATATTAGAAAAAGGAATGTT
TAAAGAATTTAATTTGCTAAATGAGAAACTTTTAAAAACTAAGGATAAAATTCTAAAGAATACTCAAAAAAATAAAAAAC
AAAGCAATAAAATTACTTTAAAAAATACCCAGCTTGCTAGTGTGATTTCTGCTATTTCTCATGAGCTTAAAAATCCATTA
AGCGTGATTAATCTTAGCTTAGAAATGCTAAAAGATGAGGAATTAGAAGATAAAAAATTAAAAAAGGAATTGCTAGGAAA
AATTTCGCGTCAAAGCATTAAACTTAATGCTTTGACCCATAAGCTTAATTTTGTTTTTAATCTTAATAGTGAAGCCTTGC
AAATGCAAGAATTTGATCTTTTTTCTCTGTGTGAAAAAATCACTAAAAACCCAGGCTTTGAAAGAGTTGTATTGCAAGGT
AAAAGCACGAAAGTTAAGGCTGATGAATTTTTAATCGAGCAAGTGATTATAAATTTACTTTCTAATGCTTTAAAATATAG
TCAAAAAGAAGTCATTTTAACAGCAAGAGATCAAAAGATAATAGTGCAAGATTTTGGAAAAGGCATAGAAAAAGATAAAA
TAAAATTGATTACAAAAAAATTTTATAAAATTGATGTAAAAAGTGATAATTCTTTTGGTTTGGGACTTTTTTTAGTAAAG
AAAATTTTAAATATACATAAAAGTTATCTTGAAATTTCTAGCACTTTAGGTTATGGTTCTAATTTTAGCTTTAAACTCAG
TCAAGGATAA

Upstream 100 bases:

>100_bases
CAAGTGATAAAACAATCAATATAGCTCTAACAAGACTTAGAAATAAATTTCCAAAACTAAAAGATCATATTATAAGCGTT
AGAGGTGTTGGCTATAAATT

Downstream 100 bases:

>100_bases
AAAATGGCTCTTATAGATTTAATTGAAGCTTCAAAAAAATTTGGAGATACAATAGTTTTAAATGAAGCAAATTTTAGTGC
AAACGAGGGAGAAAAGATTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLKTKNIFIVFFVVLALIFGFIFYTFTNSYLNFLLIKQYKQKIKSLDDVLKFSLLEHLNNANIKDFAKDTRADFIILNNN
MKISSVKNPDFFSNLKEGEILNFNSKKILTKSFIYKGYKYVIIVYPRFLDLELFWTKITIGFGVCLLFVFILMLLLGRRI
EKNFNKILDFLDSIGNHKVVILEKGMFKEFNLLNEKLLKTKDKILKNTQKNKKQSNKITLKNTQLASVISAISHELKNPL
SVINLSLEMLKDEELEDKKLKKELLGKISRQSIKLNALTHKLNFVFNLNSEALQMQEFDLFSLCEKITKNPGFERVVLQG
KSTKVKADEFLIEQVIINLLSNALKYSQKEVILTARDQKIIVQDFGKGIEKDKIKLITKKFYKIDVKSDNSFGLGLFLVK
KILNIHKSYLEISSTLGYGSNFSFKLSQG

Sequences:

>Translated_429_residues
MLKTKNIFIVFFVVLALIFGFIFYTFTNSYLNFLLIKQYKQKIKSLDDVLKFSLLEHLNNANIKDFAKDTRADFIILNNN
MKISSVKNPDFFSNLKEGEILNFNSKKILTKSFIYKGYKYVIIVYPRFLDLELFWTKITIGFGVCLLFVFILMLLLGRRI
EKNFNKILDFLDSIGNHKVVILEKGMFKEFNLLNEKLLKTKDKILKNTQKNKKQSNKITLKNTQLASVISAISHELKNPL
SVINLSLEMLKDEELEDKKLKKELLGKISRQSIKLNALTHKLNFVFNLNSEALQMQEFDLFSLCEKITKNPGFERVVLQG
KSTKVKADEFLIEQVIINLLSNALKYSQKEVILTARDQKIIVQDFGKGIEKDKIKLITKKFYKIDVKSDNSFGLGLFLVK
KILNIHKSYLEISSTLGYGSNFSFKLSQG
>Mature_429_residues
MLKTKNIFIVFFVVLALIFGFIFYTFTNSYLNFLLIKQYKQKIKSLDDVLKFSLLEHLNNANIKDFAKDTRADFIILNNN
MKISSVKNPDFFSNLKEGEILNFNSKKILTKSFIYKGYKYVIIVYPRFLDLELFWTKITIGFGVCLLFVFILMLLLGRRI
EKNFNKILDFLDSIGNHKVVILEKGMFKEFNLLNEKLLKTKDKILKNTQKNKKQSNKITLKNTQLASVISAISHELKNPL
SVINLSLEMLKDEELEDKKLKKELLGKISRQSIKLNALTHKLNFVFNLNSEALQMQEFDLFSLCEKITKNPGFERVVLQG
KSTKVKADEFLIEQVIINLLSNALKYSQKEVILTARDQKIIVQDFGKGIEKDKIKLITKKFYKIDVKSDNSFGLGLFLVK
KILNIHKSYLEISSTLGYGSNFSFKLSQG

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=217, Percent_Identity=27.1889400921659, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=24.5901639344262, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI145693157, Length=218, Percent_Identity=26.1467889908257, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49665; Mature: 49665

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTKNIFIVFFVVLALIFGFIFYTFTNSYLNFLLIKQYKQKIKSLDDVLKFSLLEHLNN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ANIKDFAKDTRADFIILNNNMKISSVKNPDFFSNLKEGEILNFNSKKILTKSFIYKGYKY
CCHHHHHHHCCCCEEEEECCEEEECCCCCHHHHCCCCCCEECCCCCHHHHHHHHHCCEEE
VIIVYPRFLDLELFWTKITIGFGVCLLFVFILMLLLGRRIEKNFNKILDFLDSIGNHKVV
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ILEKGMFKEFNLLNEKLLKTKDKILKNTQKNKKQSNKITLKNTQLASVISAISHELKNPL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCCH
SVINLSLEMLKDEELEDKKLKKELLGKISRQSIKLNALTHKLNFVFNLNSEALQMQEFDL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEHHHHHEEEEEEEECCHHHHHHHHCHH
FSLCEKITKNPGFERVVLQGKSTKVKADEFLIEQVIINLLSNALKYSQKEVILTARDQKI
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEE
IVQDFGKGIEKDKIKLITKKFYKIDVKSDNSFGLGLFLVKKILNIHKSYLEISSTLGYGS
HHHHHCCCCCHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
NFSFKLSQG
CCEEEECCC
>Mature Secondary Structure
MLKTKNIFIVFFVVLALIFGFIFYTFTNSYLNFLLIKQYKQKIKSLDDVLKFSLLEHLNN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ANIKDFAKDTRADFIILNNNMKISSVKNPDFFSNLKEGEILNFNSKKILTKSFIYKGYKY
CCHHHHHHHCCCCEEEEECCEEEECCCCCHHHHCCCCCCEECCCCCHHHHHHHHHCCEEE
VIIVYPRFLDLELFWTKITIGFGVCLLFVFILMLLLGRRIEKNFNKILDFLDSIGNHKVV
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ILEKGMFKEFNLLNEKLLKTKDKILKNTQKNKKQSNKITLKNTQLASVISAISHELKNPL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCCH
SVINLSLEMLKDEELEDKKLKKELLGKISRQSIKLNALTHKLNFVFNLNSEALQMQEFDL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEHHHHHEEEEEEEECCHHHHHHHHCHH
FSLCEKITKNPGFERVVLQGKSTKVKADEFLIEQVIINLLSNALKYSQKEVILTARDQKI
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEE
IVQDFGKGIEKDKIKLITKKFYKIDVKSDNSFGLGLFLVKKILNIHKSYLEISSTLGYGS
HHHHHCCCCCHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
NFSFKLSQG
CCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3550103; 9278503; 2187152; 8391104 [H]