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The map label for this gene is uup [H]

Identifier: 153951421

GI number: 153951421

Start: 822291

End: 824222

Strand: Direct

Name: uup [H]

Synonym: JJD26997_0925

Alternate gene names: 153951421

Gene position: 822291-824222 (Clockwise)

Preceding gene: 153952369

Following gene: 153951781

Centisome position: 44.57

GC content: 30.02

Gene sequence:

>1932_bases
ATGGCTCTTATAGATTTAATTGAAGCTTCAAAAAAATTTGGAGATACAATAGTTTTAAATGAAGCAAATTTTAGTGCAAA
CGAGGGAGAAAAGATTGCCATTATAGGGAAAAATGGAGAAGGAAAATCTACTTTTTTAAAAACGCTTTTAGGCATACTTC
CTTTAGATAGCGGTAGAGTAATAAGACAAAATGGAAAAAGCATAGCCATGCTTTCACAAACCGTTGATTTTAACGCAAAT
TTAAGTGTAAAAGAAGCTATTAAGCAAGAGCTTGCAGAAATTTACAATGCCTTAGAAGAATATGAAATACTGCATAAAAA
ATTAGAAGAAGATCCTAGTAATAAAGATTATCTTAAAAAAATAGATACACTTATAACTTTGATTGATAGTAAAGATGCTT
GGAGTATAGAATCTAAAATAATACGCGTTTTAAAAGAATTTAGTTTGCTTGAATATGAAAATCGCATTATATCTACTTTA
AGTGGCGGAGAGATACGCCGCGTTGGACTTTGTATGCTTTTACTAAAAAATCCTGATATTTTATTGCTTGATGAACCAAC
TAATCATTTAGATGTATATATGACAAGCTTTTTGGAAGAATTGCTAAAAAATTCAAAGATGTGTGTGATTTTTATTTCCC
ATGATAGATATTTTATTGATGCTATAGCACACAAGTGTGTAGAAGTAGAGCAGGGTAAACTTAGTATTTTTAAAGGCGGA
TATGCAAACTATCTAGAGAAGAAAACACAAATTTTGCAAAGCCTTGCTAAGAGCCACGAAACTCTTTTAAAACAATTAAA
AAGTGAAGAAGAATGGCTTAGAAAAGGGGTTAAAGCAAGGCTTAAAAGAAATGAAGGACGAAAAGAACGCATTTTTAAAA
TGCGTGAGGAAGCTAAAAAAAATCCTGGAGCAATCAAACGCTTAAAACTTGAAATTTCAAGAGTGGCTTTAAATTTTAAT
GGAGAAAAAACGATCAATCGTAAAAAAATGCTTTTTGAGCTTAAAAATATAAGCAAAAATATAAACGATAAAAATCTTTT
TAAAGATTTTTCAACGCGTATTTTACAAGGTGAACGCATAGCTATCGTAGGAAGAAATGGTTGTGGGAAATCAACATTGT
TAAAAATTCTCCTAGGGCAAATCAAACAAGATAACGGTGAAATAAAACGCGGAGAGCTTAAGATAGGATATTTTGATCAG
GCTAGAAGCTTGGTAAATTCTGATAAAAGCTTGCTTGAAATTTTTTGTCCCAATGGTGGAGATAGGGTTGAAGTTCGTGG
TAAAAATATGCATGTTTATGGATATTTGAAAAATTTTTTATTTCCTAAGGAATTTTTAGATAAAAGCGTAACTCTTTTAA
GTGGCGGAGAGAAAAATCGCGTTGCTTTAGCCTTACTTTTCACTAAAGAATATGATGTTTTGATTTTAGATGAGCCAACT
AATGATCTTGATATAGCTACGATTAATATATTAGAAGAATACTTACTTAGTTTTGGAGGGGCTATTTTGTTAGTATCACA
CGATAGATATTTTGTTGATAAAATCGCAACAAAACTTTATGCTTTTGAGGGAAATGGATATATAAATATTTTACACACTC
TTTACACTGAATATCTTGAAAATGAAAAAGAAGTTGAAGAATTGGATAATTTTGCCTTAGAGCTTCAAACCCAAGAGCAA
AATAATAACCAAAAAGAAAAAAGCTCTAAAAAATTAAGCTACAAGGAAAATAAGATATTAAAAAACCATCCTGAAAAAAT
AGATTTTTTAGAGCAAAAGATAGCTAAATTAAATCAAAATTTATCCAATCCAAATGTATACCAAGAAGTAGGCATTAACA
AGCTTTATCAAGAGCTTGAAGCAATGCAAAAAGAACTTGAAATTCTAGAAAATGAGTATTTTTTAGTATTAGAGAAAAGT
GAGAATTTATAA

Upstream 100 bases:

>100_bases
AGTAAAGAAAATTTTAAATATACATAAAAGTTATCTTGAAATTTCTAGCACTTTAGGTTATGGTTCTAATTTTAGCTTTA
AACTCAGTCAAGGATAAAAA

Downstream 100 bases:

>100_bases
TTAAAGAGATTTTATATTTTTTATTCTATGGAGCGGGAAACGAGATTTGAATAATGCTAATAAAAACACTACTATACAAT
ATTTATAAATAGTATAAAAA

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 642

Protein sequence:

>643_residues
MALIDLIEASKKFGDTIVLNEANFSANEGEKIAIIGKNGEGKSTFLKTLLGILPLDSGRVIRQNGKSIAMLSQTVDFNAN
LSVKEAIKQELAEIYNALEEYEILHKKLEEDPSNKDYLKKIDTLITLIDSKDAWSIESKIIRVLKEFSLLEYENRIISTL
SGGEIRRVGLCMLLLKNPDILLLDEPTNHLDVYMTSFLEELLKNSKMCVIFISHDRYFIDAIAHKCVEVEQGKLSIFKGG
YANYLEKKTQILQSLAKSHETLLKQLKSEEEWLRKGVKARLKRNEGRKERIFKMREEAKKNPGAIKRLKLEISRVALNFN
GEKTINRKKMLFELKNISKNINDKNLFKDFSTRILQGERIAIVGRNGCGKSTLLKILLGQIKQDNGEIKRGELKIGYFDQ
ARSLVNSDKSLLEIFCPNGGDRVEVRGKNMHVYGYLKNFLFPKEFLDKSVTLLSGGEKNRVALALLFTKEYDVLILDEPT
NDLDIATINILEEYLLSFGGAILLVSHDRYFVDKIATKLYAFEGNGYINILHTLYTEYLENEKEVEELDNFALELQTQEQ
NNNQKEKSSKKLSYKENKILKNHPEKIDFLEQKIAKLNQNLSNPNVYQEVGINKLYQELEAMQKELEILENEYFLVLEKS
ENL

Sequences:

>Translated_643_residues
MALIDLIEASKKFGDTIVLNEANFSANEGEKIAIIGKNGEGKSTFLKTLLGILPLDSGRVIRQNGKSIAMLSQTVDFNAN
LSVKEAIKQELAEIYNALEEYEILHKKLEEDPSNKDYLKKIDTLITLIDSKDAWSIESKIIRVLKEFSLLEYENRIISTL
SGGEIRRVGLCMLLLKNPDILLLDEPTNHLDVYMTSFLEELLKNSKMCVIFISHDRYFIDAIAHKCVEVEQGKLSIFKGG
YANYLEKKTQILQSLAKSHETLLKQLKSEEEWLRKGVKARLKRNEGRKERIFKMREEAKKNPGAIKRLKLEISRVALNFN
GEKTINRKKMLFELKNISKNINDKNLFKDFSTRILQGERIAIVGRNGCGKSTLLKILLGQIKQDNGEIKRGELKIGYFDQ
ARSLVNSDKSLLEIFCPNGGDRVEVRGKNMHVYGYLKNFLFPKEFLDKSVTLLSGGEKNRVALALLFTKEYDVLILDEPT
NDLDIATINILEEYLLSFGGAILLVSHDRYFVDKIATKLYAFEGNGYINILHTLYTEYLENEKEVEELDNFALELQTQEQ
NNNQKEKSSKKLSYKENKILKNHPEKIDFLEQKIAKLNQNLSNPNVYQEVGINKLYQELEAMQKELEILENEYFLVLEKS
ENL
>Mature_642_residues
ALIDLIEASKKFGDTIVLNEANFSANEGEKIAIIGKNGEGKSTFLKTLLGILPLDSGRVIRQNGKSIAMLSQTVDFNANL
SVKEAIKQELAEIYNALEEYEILHKKLEEDPSNKDYLKKIDTLITLIDSKDAWSIESKIIRVLKEFSLLEYENRIISTLS
GGEIRRVGLCMLLLKNPDILLLDEPTNHLDVYMTSFLEELLKNSKMCVIFISHDRYFIDAIAHKCVEVEQGKLSIFKGGY
ANYLEKKTQILQSLAKSHETLLKQLKSEEEWLRKGVKARLKRNEGRKERIFKMREEAKKNPGAIKRLKLEISRVALNFNG
EKTINRKKMLFELKNISKNINDKNLFKDFSTRILQGERIAIVGRNGCGKSTLLKILLGQIKQDNGEIKRGELKIGYFDQA
RSLVNSDKSLLEIFCPNGGDRVEVRGKNMHVYGYLKNFLFPKEFLDKSVTLLSGGEKNRVALALLFTKEYDVLILDEPTN
DLDIATINILEEYLLSFGGAILLVSHDRYFVDKIATKLYAFEGNGYINILHTLYTEYLENEKEVEELDNFALELQTQEQN
NNQKEKSSKKLSYKENKILKNHPEKIDFLEQKIAKLNQNLSNPNVYQEVGINKLYQELEAMQKELEILENEYFLVLEKSE
NL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=547, Percent_Identity=27.6051188299817, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI10947135, Length=522, Percent_Identity=28.1609195402299, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI69354671, Length=522, Percent_Identity=28.1609195402299, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI10947137, Length=532, Percent_Identity=27.4436090225564, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI27881506, Length=532, Percent_Identity=27.4436090225564, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1787182, Length=632, Percent_Identity=36.0759493670886, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI2367384, Length=540, Percent_Identity=34.4444444444444, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI1789751, Length=622, Percent_Identity=28.2958199356913, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1787041, Length=523, Percent_Identity=29.2543021032505, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1788506, Length=543, Percent_Identity=24.1252302025783, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87081834, Length=224, Percent_Identity=30.8035714285714, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789672, Length=236, Percent_Identity=23.3050847457627, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789891, Length=194, Percent_Identity=30.9278350515464, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788225, Length=263, Percent_Identity=25.8555133079848, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786703, Length=197, Percent_Identity=30.4568527918782, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1789593, Length=240, Percent_Identity=25, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI48994883, Length=242, Percent_Identity=28.099173553719, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786872, Length=236, Percent_Identity=24.5762711864407, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790544, Length=241, Percent_Identity=22.4066390041494, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787500, Length=250, Percent_Identity=23.2, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789032, Length=209, Percent_Identity=27.7511961722488, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786698, Length=210, Percent_Identity=29.5238095238095, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1790467, Length=212, Percent_Identity=26.8867924528302, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787029, Length=212, Percent_Identity=25.4716981132075, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=527, Percent_Identity=26.5654648956357, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17555318, Length=512, Percent_Identity=27.734375, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17553372, Length=528, Percent_Identity=28.5984848484849, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17555800, Length=188, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=551, Percent_Identity=28.4936479128857, Blast_Score=171, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6320874, Length=532, Percent_Identity=27.0676691729323, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6325030, Length=255, Percent_Identity=29.8039215686275, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6324314, Length=174, Percent_Identity=35.0574712643678, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323278, Length=396, Percent_Identity=26.7676767676768, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24666836, Length=546, Percent_Identity=29.1208791208791, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24641342, Length=552, Percent_Identity=28.4420289855072, Blast_Score=163, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24642252, Length=525, Percent_Identity=27.047619047619, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI18859989, Length=525, Percent_Identity=27.047619047619, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24661270, Length=522, Percent_Identity=25.095785440613, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21355589, Length=522, Percent_Identity=25.095785440613, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI116007328, Length=193, Percent_Identity=27.4611398963731, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28574150, Length=193, Percent_Identity=27.4611398963731, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 73788; Mature: 73657

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIDLIEASKKFGDTIVLNEANFSANEGEKIAIIGKNGEGKSTFLKTLLGILPLDSGRV
CCHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCE
IRQNGKSIAMLSQTVDFNANLSVKEAIKQELAEIYNALEEYEILHKKLEEDPSNKDYLKK
EECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IDTLITLIDSKDAWSIESKIIRVLKEFSLLEYENRIISTLSGGEIRRVGLCMLLLKNPDI
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEECCCCE
LLLDEPTNHLDVYMTSFLEELLKNSKMCVIFISHDRYFIDAIAHKCVEVEQGKLSIFKGG
EEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCC
YANYLEKKTQILQSLAKSHETLLKQLKSEEEWLRKGVKARLKRNEGRKERIFKMREEAKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
NPGAIKRLKLEISRVALNFNGEKTINRKKMLFELKNISKNINDKNLFKDFSTRILQGERI
CCCHHHHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
AIVGRNGCGKSTLLKILLGQIKQDNGEIKRGELKIGYFDQARSLVNSDKSLLEIFCPNGG
EEEECCCCCHHHHHHHHHHHHCCCCCCEEECEEEEEEHHHHHHHHCCCCCEEEEECCCCC
DRVEVRGKNMHVYGYLKNFLFPKEFLDKSVTLLSGGEKNRVALALLFTKEYDVLILDEPT
CEEEEECCCEEEEEEHHHCCCCHHHHCCCEEEECCCCCCCEEEEEEEECCCCEEEEECCC
NDLDIATINILEEYLLSFGGAILLVSHDRYFVDKIATKLYAFEGNGYINILHTLYTEYLE
CCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEEECCCEEEHHHHHHHHHHC
NEKEVEELDNFALELQTQEQNNNQKEKSSKKLSYKENKILKNHPEKIDFLEQKIAKLNQN
CHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCHHHCCHHHCCCHHHHHHHHHHHHHHCC
LSNPNVYQEVGINKLYQELEAMQKELEILENEYFLVLEKSENL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
>Mature Secondary Structure 
ALIDLIEASKKFGDTIVLNEANFSANEGEKIAIIGKNGEGKSTFLKTLLGILPLDSGRV
CHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCE
IRQNGKSIAMLSQTVDFNANLSVKEAIKQELAEIYNALEEYEILHKKLEEDPSNKDYLKK
EECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IDTLITLIDSKDAWSIESKIIRVLKEFSLLEYENRIISTLSGGEIRRVGLCMLLLKNPDI
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEECCCCE
LLLDEPTNHLDVYMTSFLEELLKNSKMCVIFISHDRYFIDAIAHKCVEVEQGKLSIFKGG
EEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCC
YANYLEKKTQILQSLAKSHETLLKQLKSEEEWLRKGVKARLKRNEGRKERIFKMREEAKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
NPGAIKRLKLEISRVALNFNGEKTINRKKMLFELKNISKNINDKNLFKDFSTRILQGERI
CCCHHHHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
AIVGRNGCGKSTLLKILLGQIKQDNGEIKRGELKIGYFDQARSLVNSDKSLLEIFCPNGG
EEEECCCCCHHHHHHHHHHHHCCCCCCEEECEEEEEEHHHHHHHHCCCCCEEEEECCCCC
DRVEVRGKNMHVYGYLKNFLFPKEFLDKSVTLLSGGEKNRVALALLFTKEYDVLILDEPT
CEEEEECCCEEEEEEHHHCCCCHHHHCCCEEEECCCCCCCEEEEEEEECCCCEEEEECCC
NDLDIATINILEEYLLSFGGAILLVSHDRYFVDKIATKLYAFEGNGYINILHTLYTEYLE
CCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEEECCCEEEHHHHHHHHHHC
NEKEVEELDNFALELQTQEQNNNQKEKSSKKLSYKENKILKNHPEKIDFLEQKIAKLNQN
CHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCHHHCCHHHCCCHHHHHHHHHHHHHHCC
LSNPNVYQEVGINKLYQELEAMQKELEILENEYFLVLEKSENL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9139905; 7751275 [H]