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The map label for this gene is fecD [C]

Identifier: 153952324

GI number: 153952324

Start: 1504518

End: 1505576

Strand: Direct

Name: fecD [C]

Synonym: JJD26997_1703

Alternate gene names: 153952324

Gene position: 1504518-1505576 (Clockwise)

Preceding gene: 153951923

Following gene: 153951548

Centisome position: 81.54

GC content: 38.62

Gene sequence:

>1059_bases
ATGCAAAATAAAATTGTAGCCACGCTCAAAGCACATCGAAAAAGAGAATTAAAAAGATTTTATATCATCATAAGTTTTTT
AATGATTGCTTTCGTCTCTTTGATTTTTGACATCGCTACAGGTCCTTCACTTATTACACCAAAAGAGATTTTAAATGCAC
TCTTATCGCCTTTTTCCTCAAAAGAAATCGACTCAACAACCTTAAGCATAGTTTATGACTTAAGACTTCCTATGGCTTTG
ATGGCTTTGGTTGTGGGGGCGGCTTTAGGTATAGGCGGAGCTGAAATTCAAACTTTACTCAATAACCCTATGGCAAGCCC
CTACACTCTAGGACTTGCAGCGGCAAGTGGCTTTGGAGCGTCTTTGGTGATAGCCTTTGGGAGTTTTGGCTTACCCCTTA
TCACGGCTGTTCCTGTGGGAGCGTTTTTAATGACGATGTTAGCTGCCTCTGTGCTTTTTGGTTTTGCAAGTTTTAAGAGA
TTTGACTCGGCTATGCTTGTTTTGGTAGGAATTTCTTTACTTTTTCTATTTCAATCTTTCTTATCTTTAGTGCAGTATCT
TTCTGCTCCTGAAATTTCACAACAAATTCTTTTTTGGCTTTTTGGTTCTTTACTAAAGTCAAATTGGACGAATTTGTCCA
TCGTTAGTATAGCAACTCTCATTTGTGTTTTATTTTTACTGCGTGATTCTTGGGCTTTAACCGCACTTAAATTAGGTGAG
GCAAGGGCTAAAAGTATGGGGATTGATCTCAATTTTCTACGCTTCAAAACTCTTGTTTTGGTTTCCATTATGACAGCGAC
TGCCATTTCTTTTGTGGGCGTTATAGGCTTTATAGGGCTTGTTTCGCCACACATAGCAAGGATGTTGGTTGGAGAGGACC
AGAGATTTTTCCTACCGAGTGCTATGTTTGTGGGAGCAGCGTTTTTATCCATCGCTTCAGTTTTATCTAAGGTGATTATA
CCAGGAGCCTTATTTCCCGTTGGTATCATCACTTCTTTAATTGGTGTTCCTTTTTTCTTTTGGATTATTTTTTCGAGGAA
AAACTATGCTAAAGCTTGA

Upstream 100 bases:

>100_bases
AGCCTTTTTAAAGATATTGACCCCTTAAAAACTTATTTGGATTTTCATCAAAAATTTCTTCTAGCTAAACCTCAAGGTAC
TTTTATGATTAAGGCAAAAA

Downstream 100 bases:

>100_bases
AAATTTCAGTGTGCATCGCAAAGATTTATGTGTGGTAAATCAAATCAATCTAAGCCTTCAAAGAGGTAAAATTTACGCTA
TCTTAGGTGCAAATGGAGCG

Product: heme/hemin ABC transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MQNKIVATLKAHRKRELKRFYIIISFLMIAFVSLIFDIATGPSLITPKEILNALLSPFSSKEIDSTTLSIVYDLRLPMAL
MALVVGAALGIGGAEIQTLLNNPMASPYTLGLAAASGFGASLVIAFGSFGLPLITAVPVGAFLMTMLAASVLFGFASFKR
FDSAMLVLVGISLLFLFQSFLSLVQYLSAPEISQQILFWLFGSLLKSNWTNLSIVSIATLICVLFLLRDSWALTALKLGE
ARAKSMGIDLNFLRFKTLVLVSIMTATAISFVGVIGFIGLVSPHIARMLVGEDQRFFLPSAMFVGAAFLSIASVLSKVII
PGALFPVGIITSLIGVPFFFWIIFSRKNYAKA

Sequences:

>Translated_352_residues
MQNKIVATLKAHRKRELKRFYIIISFLMIAFVSLIFDIATGPSLITPKEILNALLSPFSSKEIDSTTLSIVYDLRLPMAL
MALVVGAALGIGGAEIQTLLNNPMASPYTLGLAAASGFGASLVIAFGSFGLPLITAVPVGAFLMTMLAASVLFGFASFKR
FDSAMLVLVGISLLFLFQSFLSLVQYLSAPEISQQILFWLFGSLLKSNWTNLSIVSIATLICVLFLLRDSWALTALKLGE
ARAKSMGIDLNFLRFKTLVLVSIMTATAISFVGVIGFIGLVSPHIARMLVGEDQRFFLPSAMFVGAAFLSIASVLSKVII
PGALFPVGIITSLIGVPFFFWIIFSRKNYAKA
>Mature_352_residues
MQNKIVATLKAHRKRELKRFYIIISFLMIAFVSLIFDIATGPSLITPKEILNALLSPFSSKEIDSTTLSIVYDLRLPMAL
MALVVGAALGIGGAEIQTLLNNPMASPYTLGLAAASGFGASLVIAFGSFGLPLITAVPVGAFLMTMLAASVLFGFASFKR
FDSAMLVLVGISLLFLFQSFLSLVQYLSAPEISQQILFWLFGSLLKSNWTNLSIVSIATLICVLFLLRDSWALTALKLGE
ARAKSMGIDLNFLRFKTLVLVSIMTATAISFVGVIGFIGLVSPHIARMLVGEDQRFFLPSAMFVGAAFLSIASVLSKVII
PGALFPVGIITSLIGVPFFFWIIFSRKNYAKA

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=289, Percent_Identity=36.3321799307958, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1790741, Length=288, Percent_Identity=32.2916666666667, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788004, Length=278, Percent_Identity=30.9352517985612, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786805, Length=297, Percent_Identity=33.6700336700337, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786347, Length=283, Percent_Identity=30.7420494699647, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786804, Length=324, Percent_Identity=26.2345679012346, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 38030; Mature: 38030

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNKIVATLKAHRKRELKRFYIIISFLMIAFVSLIFDIATGPSLITPKEILNALLSPFSS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
KEIDSTTLSIVYDLRLPMALMALVVGAALGIGGAEIQTLLNNPMASPYTLGLAAASGFGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCH
SLVIAFGSFGLPLITAVPVGAFLMTMLAASVLFGFASFKRFDSAMLVLVGISLLFLFQSF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLVQYLSAPEISQQILFWLFGSLLKSNWTNLSIVSIATLICVLFLLRDSWALTALKLGE
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ARAKSMGIDLNFLRFKTLVLVSIMTATAISFVGVIGFIGLVSPHIARMLVGEDQRFFLPS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
AMFVGAAFLSIASVLSKVIIPGALFPVGIITSLIGVPFFFWIIFSRKNYAKA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQNKIVATLKAHRKRELKRFYIIISFLMIAFVSLIFDIATGPSLITPKEILNALLSPFSS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
KEIDSTTLSIVYDLRLPMALMALVVGAALGIGGAEIQTLLNNPMASPYTLGLAAASGFGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCH
SLVIAFGSFGLPLITAVPVGAFLMTMLAASVLFGFASFKRFDSAMLVLVGISLLFLFQSF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLVQYLSAPEISQQILFWLFGSLLKSNWTNLSIVSIATLICVLFLLRDSWALTALKLGE
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ARAKSMGIDLNFLRFKTLVLVSIMTATAISFVGVIGFIGLVSPHIARMLVGEDQRFFLPS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
AMFVGAAFLSIASVLSKVIIPGALFPVGIITSLIGVPFFFWIIFSRKNYAKA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]