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The map label for this gene is hemN [H]

Identifier: 153952155

GI number: 153952155

Start: 719512

End: 720867

Strand: Direct

Name: hemN [H]

Synonym: JJD26997_0797

Alternate gene names: 153952155

Gene position: 719512-720867 (Clockwise)

Preceding gene: 153952645

Following gene: 153952441

Centisome position: 39.0

GC content: 30.16

Gene sequence:

>1356_bases
ATGAGAGATTATAAAGCTTTTGTAAAATACTCTAAAGCAGGACCACGCTATACTTCTTATCCTACAGCAGTAGAGTTTAA
TACAAATTTCAAATACGAAGAATATATAGAAATTTTAAAAAAGCAAGATAGATCTTTATCGCTTTATTTTCATTTACCAT
TTTGTAGGAGTGCTTGTTATTTTTGTGGTTGCAATGTCATTTATACTGCAAAAGAAGAGAGTAAAGAAAGGTATTTAACT
TATATTTTTAAAGAGCTCGATATTTTAAGTGCTATTTTAGATACTAAGCGTGAAGTGGTGCAAATGCACTTTGGAGGTGG
AACTCCAACTTTTTTTAGTGCTAAACAACTTCAAAGTTTGATTTTAAAAATCAGATCTGTTTTTGGAAATTTTTCTAAAG
ATGCAGAGATTAGCTGTGAGATTGATCCACGGTTTTTAAATGAGGAACAAGCCACAGTTTTAACGCAAAATGGCTTTAAT
CGTATCAGCTTTGGAGTGCAGGATTTTGATGAAAAAGTTCAAAAGGAAATTCATCGTATCCAGCCTTTTGAATTAACACA
AAATGCTTTAAATCTTGTAAGAAGCAAAGGAATAAAGTCTCTAAATATGGATTTAATTTATGGTTTGCCTTATCAAAATT
TACAAAGCTTTACACAAACCTTAGAAAAAGTTATGCTTTTAAATCCTGATCGTTTGGCGATTTTTAATTACGCTCATGTG
CCTTGGCTTAAGAAAAATATGAGAAAATTTGATGAAAATACCTTGCCAAGTCCTGATGTTAAGCTTGAAATTTTAGAATT
TTGTGAAAAATTTTTAAGCAAAAATGGCTATAAAATGATAGGAATGGATCATTTTGCAAAAGAAAATGATGAGCTTTTTA
AAGCTTTAGAAAATGGAACTTTACATAGAAATTTCCAAGGTTATACTACTAAAAGCGGTGCTGATTTAGTCGGTGTCGGG
CTTACAAGTATAGGCGAAGGACAAAAACATTATGCGCAAAATTTTAAAGATATATCAAGTTATGAGGCTGCATTAGATAG
AGGAGTTTTGCCTTTTGAAAGAGGTGTAGCTTTAAGCGATGATGATGAGCTTAGAAAAGCAGTGATTATGGAGTTAATGG
CAAATTTTAAGCTTGATATCAAGTCAATAGAAAAAGAATTTTCCATTGATTTTCAGGAGTATTTTAAAAAGGATTTAAAA
GCTTTAGAAGAATACAAAGATTTTATTAATTTTGATGAAAATTTTATCAAAGTCAATGAAACAGGTGTTTTGCTTATAAG
AAATATTGCTATGTGTTTTGATGCTTATATGAAAAACATTAGTGAAGATAAAAAAGTATTCTCAAAAACGGTGTAA

Upstream 100 bases:

>100_bases
GAAGTTAGTATTGATCTTGAAAAATTAATTTCTAAAATCAAACAAGAGCATCCAAATTTATTTGTAGATATGCAAGCGAT
GATAGAAAAGGTAAATCAAA

Downstream 100 bases:

>100_bases
GATGAAATTTAGTCAAATAAGTGATGCTTGTGTTAAATGTGGCAAATGTATACCTGTTTGTACTATACATGAAGAAAATC
GCGATGAAATTACTAGTCCA

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MRDYKAFVKYSKAGPRYTSYPTAVEFNTNFKYEEYIEILKKQDRSLSLYFHLPFCRSACYFCGCNVIYTAKEESKERYLT
YIFKELDILSAILDTKREVVQMHFGGGTPTFFSAKQLQSLILKIRSVFGNFSKDAEISCEIDPRFLNEEQATVLTQNGFN
RISFGVQDFDEKVQKEIHRIQPFELTQNALNLVRSKGIKSLNMDLIYGLPYQNLQSFTQTLEKVMLLNPDRLAIFNYAHV
PWLKKNMRKFDENTLPSPDVKLEILEFCEKFLSKNGYKMIGMDHFAKENDELFKALENGTLHRNFQGYTTKSGADLVGVG
LTSIGEGQKHYAQNFKDISSYEAALDRGVLPFERGVALSDDDELRKAVIMELMANFKLDIKSIEKEFSIDFQEYFKKDLK
ALEEYKDFINFDENFIKVNETGVLLIRNIAMCFDAYMKNISEDKKVFSKTV

Sequences:

>Translated_451_residues
MRDYKAFVKYSKAGPRYTSYPTAVEFNTNFKYEEYIEILKKQDRSLSLYFHLPFCRSACYFCGCNVIYTAKEESKERYLT
YIFKELDILSAILDTKREVVQMHFGGGTPTFFSAKQLQSLILKIRSVFGNFSKDAEISCEIDPRFLNEEQATVLTQNGFN
RISFGVQDFDEKVQKEIHRIQPFELTQNALNLVRSKGIKSLNMDLIYGLPYQNLQSFTQTLEKVMLLNPDRLAIFNYAHV
PWLKKNMRKFDENTLPSPDVKLEILEFCEKFLSKNGYKMIGMDHFAKENDELFKALENGTLHRNFQGYTTKSGADLVGVG
LTSIGEGQKHYAQNFKDISSYEAALDRGVLPFERGVALSDDDELRKAVIMELMANFKLDIKSIEKEFSIDFQEYFKKDLK
ALEEYKDFINFDENFIKVNETGVLLIRNIAMCFDAYMKNISEDKKVFSKTV
>Mature_451_residues
MRDYKAFVKYSKAGPRYTSYPTAVEFNTNFKYEEYIEILKKQDRSLSLYFHLPFCRSACYFCGCNVIYTAKEESKERYLT
YIFKELDILSAILDTKREVVQMHFGGGTPTFFSAKQLQSLILKIRSVFGNFSKDAEISCEIDPRFLNEEQATVLTQNGFN
RISFGVQDFDEKVQKEIHRIQPFELTQNALNLVRSKGIKSLNMDLIYGLPYQNLQSFTQTLEKVMLLNPDRLAIFNYAHV
PWLKKNMRKFDENTLPSPDVKLEILEFCEKFLSKNGYKMIGMDHFAKENDELFKALENGTLHRNFQGYTTKSGADLVGVG
LTSIGEGQKHYAQNFKDISSYEAALDRGVLPFERGVALSDDDELRKAVIMELMANFKLDIKSIEKEFSIDFQEYFKKDLK
ALEEYKDFINFDENFIKVNETGVLLIRNIAMCFDAYMKNISEDKKVFSKTV

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Escherichia coli, GI87082341, Length=452, Percent_Identity=44.6902654867257, Blast_Score=387, Evalue=1e-108,
Organism=Escherichia coli, GI1789325, Length=245, Percent_Identity=30.2040816326531, Blast_Score=122, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004558
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 52349; Mature: 52349

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDYKAFVKYSKAGPRYTSYPTAVEFNTNFKYEEYIEILKKQDRSLSLYFHLPFCRSACY
CCCHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHH
FCGCNVIYTAKEESKERYLTYIFKELDILSAILDTKREVVQMHFGGGTPTFFSAKQLQSL
HHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHH
ILKIRSVFGNFSKDAEISCEIDPRFLNEEQATVLTQNGFNRISFGVQDFDEKVQKEIHRI
HHHHHHHHCCCCCCCEEEEEECCHHCCCCHHEEEECCCCCHHHCCHHHHHHHHHHHHHHC
QPFELTQNALNLVRSKGIKSLNMDLIYGLPYQNLQSFTQTLEKVMLLNPDRLAIFNYAHV
CCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PWLKKNMRKFDENTLPSPDVKLEILEFCEKFLSKNGYKMIGMDHFAKENDELFKALENGT
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCHHHHCCHHHHHHHHHCCC
LHRNFQGYTTKSGADLVGVGLTSIGEGQKHYAQNFKDISSYEAALDRGVLPFERGVALSD
EECCCCCCCCCCCCCEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCC
DDELRKAVIMELMANFKLDIKSIEKEFSIDFQEYFKKDLKALEEYKDFINFDENFIKVNE
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
TGVLLIRNIAMCFDAYMKNISEDKKVFSKTV
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MRDYKAFVKYSKAGPRYTSYPTAVEFNTNFKYEEYIEILKKQDRSLSLYFHLPFCRSACY
CCCHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHH
FCGCNVIYTAKEESKERYLTYIFKELDILSAILDTKREVVQMHFGGGTPTFFSAKQLQSL
HHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHH
ILKIRSVFGNFSKDAEISCEIDPRFLNEEQATVLTQNGFNRISFGVQDFDEKVQKEIHRI
HHHHHHHHCCCCCCCEEEEEECCHHCCCCHHEEEECCCCCHHHCCHHHHHHHHHHHHHHC
QPFELTQNALNLVRSKGIKSLNMDLIYGLPYQNLQSFTQTLEKVMLLNPDRLAIFNYAHV
CCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PWLKKNMRKFDENTLPSPDVKLEILEFCEKFLSKNGYKMIGMDHFAKENDELFKALENGT
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCHHHHCCHHHHHHHHHCCC
LHRNFQGYTTKSGADLVGVGLTSIGEGQKHYAQNFKDISSYEAALDRGVLPFERGVALSD
EECCCCCCCCCCCCCEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCC
DDELRKAVIMELMANFKLDIKSIEKEFSIDFQEYFKKDLKALEEYKDFINFDENFIKVNE
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
TGVLLIRNIAMCFDAYMKNISEDKKVFSKTV
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]