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The map label for this gene is aspS [H]

Identifier: 153951485

GI number: 153951485

Start: 1201542

End: 1203293

Strand: Direct

Name: aspS [H]

Synonym: JJD26997_1359

Alternate gene names: 153951485

Gene position: 1201542-1203293 (Clockwise)

Preceding gene: 153952590

Following gene: 153952659

Centisome position: 65.12

GC content: 35.39

Gene sequence:

>1752_bases
TTGCGAAGTCATTATAATATAGACTTGGGAATTTCCCATGTTGGTCAAAGCGTTAAACTTTGCGGTTGGGTAAATAGCTA
CCGCGATCATGGTGGAGTTATTTTTATAGATTTAAGAGATAGAAGTGGTATTATCCAACTTGTTTGCGATCCAAATGATA
GCAAAGAAGCTCATGAAATCGCTTCCAATGCAAGAAATGAATTTGTACTTATTGCAGAAGGTACTATTCGTCCGCGGGGC
GAAGGACTTGTAAATCCTAAATTAAAAACAGGAGAAATCGAAGTAGTCGTTTCTAAACTTACCATAGAAAATGAAAGTAT
CGTACCTCCTTTTGCCATCGCTGATGAAAGTGTAAATGAAGAATTACGCTTAAAATATCGCTTTTTAGATTTAAGAAATC
CTAAACTTTATGAAAATTTTGCCTTGCGTTCTAAAGCTTGCATAGCAGCTAGAAATTCTTTGGCAAATATGGGATTTTTA
GAAGTTGAAACCCCTATTCTCACCAAAGCTACTCCTGAAGGTGCAAGGGATTATCTTGTACCTTCTCGTGTGCATCAGGG
TGAATTTTATGCTCTTCCACAAAGCCCTCAGCTTTTCAAACAACTTTTAATGTGTAGCGGTTTTGATCGTTATTTTCAAA
TCGCAAAATGTTTTAGAGATGAAGATTTAAGAGCTGATCGCCAACCTGAATTCACACAAATTGATGTTGAAATGAGTTTT
TGTGAAAAAAAAGATGTGATCAATGTAGCTGAAACTTTTTTAAAAGACATTTTCAAAGCTTGTGGCAAAGAAATTCAAAC
CCCTTTTAGACAAATGCAATACAAAGACGCTATGGAGAATTATGGCTCTGATAAGCCGGATTTAAGATTTGATCTTAAAT
TTATTGATGTGATTGATATTTTCGCTAAGTCAAATAATGAAATTTTTGCAAATATTGCCAAAGATACAAAGAAAAATCGC
ATCAAAGCCATACGCGTTCCAAAAGGCGATACTATTTTTTCAAAAAGACAAATGCAAAGATTTGAAGAATTTGTGCGTAA
ATTTGGTGCAGAGGGCTTAGCTTTCATACAAGTTAAAGAAGATGGGCTTAAAGGTCCACTTTGCAAATTCTTTAGCGAAG
AAGATTTAAATGAGCTAAGCAAACGCTGTAAACTTGAAGTAGGAGATGTGGTATTTTTTGGTGCAGGAGCTAAAAAAACC
GTGCTTGATTATATGGGAAGATTTAGAATTTTCTTAGCCAACGAGTTAAATCTTATAGATCCAAATGCCTTAGAATTCTT
ATGGGTTGTTGATTTTCCTATGTTTGAACAAAATGATGATGGAAGTTATTCTGCGATGCACCATCCTTTTACCATGCCAA
AAAATATCGACGAGAATGATTTAGAAGAAATTTCATCTATTGCTTATGATGTAGTATTAAATGGCGTTGAGCTAGGCGGA
GGCAGTATAAGAATCCATAAAAACGATATTCAACAAAAAGTATTTAAACTTTTAAATATCGATGAAGAACAACAAAAAGA
AAAATTTGGCTTCTTGCTTGATGCTTTAAGTTTTGGCGCTCCACCACATGGAGGTATCGCCATAGGACTTGATAGACTTA
TCATGCTAGTTACAGGAGCAAACAGCATACGAGAGGTTATAGCCTTTCCAAAAACTCAAAGAGCGCAATGCTTAATGACA
GAGGCTCCATCGCCTGCTAGCAATGAAGCAATGAGAGAGTTAGGAATCAAATTAAGGGAGAATATAAAATGA

Upstream 100 bases:

>100_bases
TATTTTGCATAAAAAATTATATCAAATCTTAGCAAAGCAAAAGAATAAAAATACTATAATTTTGCTCATTATCTTAAAAA
ATCTTTTTCAAGGAATAAAT

Downstream 100 bases:

>100_bases
AAGAATTGTTTTTAATCATAGGTGCACCAGGTAGTGGAAAAACTACCGATGCTAGTTTAATCGCACAAGCAGATGCGACA
AATATCACACACTATTCAAC

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MRSHYNIDLGISHVGQSVKLCGWVNSYRDHGGVIFIDLRDRSGIIQLVCDPNDSKEAHEIASNARNEFVLIAEGTIRPRG
EGLVNPKLKTGEIEVVVSKLTIENESIVPPFAIADESVNEELRLKYRFLDLRNPKLYENFALRSKACIAARNSLANMGFL
EVETPILTKATPEGARDYLVPSRVHQGEFYALPQSPQLFKQLLMCSGFDRYFQIAKCFRDEDLRADRQPEFTQIDVEMSF
CEKKDVINVAETFLKDIFKACGKEIQTPFRQMQYKDAMENYGSDKPDLRFDLKFIDVIDIFAKSNNEIFANIAKDTKKNR
IKAIRVPKGDTIFSKRQMQRFEEFVRKFGAEGLAFIQVKEDGLKGPLCKFFSEEDLNELSKRCKLEVGDVVFFGAGAKKT
VLDYMGRFRIFLANELNLIDPNALEFLWVVDFPMFEQNDDGSYSAMHHPFTMPKNIDENDLEEISSIAYDVVLNGVELGG
GSIRIHKNDIQQKVFKLLNIDEEQQKEKFGFLLDALSFGAPPHGGIAIGLDRLIMLVTGANSIREVIAFPKTQRAQCLMT
EAPSPASNEAMRELGIKLRENIK

Sequences:

>Translated_583_residues
MRSHYNIDLGISHVGQSVKLCGWVNSYRDHGGVIFIDLRDRSGIIQLVCDPNDSKEAHEIASNARNEFVLIAEGTIRPRG
EGLVNPKLKTGEIEVVVSKLTIENESIVPPFAIADESVNEELRLKYRFLDLRNPKLYENFALRSKACIAARNSLANMGFL
EVETPILTKATPEGARDYLVPSRVHQGEFYALPQSPQLFKQLLMCSGFDRYFQIAKCFRDEDLRADRQPEFTQIDVEMSF
CEKKDVINVAETFLKDIFKACGKEIQTPFRQMQYKDAMENYGSDKPDLRFDLKFIDVIDIFAKSNNEIFANIAKDTKKNR
IKAIRVPKGDTIFSKRQMQRFEEFVRKFGAEGLAFIQVKEDGLKGPLCKFFSEEDLNELSKRCKLEVGDVVFFGAGAKKT
VLDYMGRFRIFLANELNLIDPNALEFLWVVDFPMFEQNDDGSYSAMHHPFTMPKNIDENDLEEISSIAYDVVLNGVELGG
GSIRIHKNDIQQKVFKLLNIDEEQQKEKFGFLLDALSFGAPPHGGIAIGLDRLIMLVTGANSIREVIAFPKTQRAQCLMT
EAPSPASNEAMRELGIKLRENIK
>Mature_583_residues
MRSHYNIDLGISHVGQSVKLCGWVNSYRDHGGVIFIDLRDRSGIIQLVCDPNDSKEAHEIASNARNEFVLIAEGTIRPRG
EGLVNPKLKTGEIEVVVSKLTIENESIVPPFAIADESVNEELRLKYRFLDLRNPKLYENFALRSKACIAARNSLANMGFL
EVETPILTKATPEGARDYLVPSRVHQGEFYALPQSPQLFKQLLMCSGFDRYFQIAKCFRDEDLRADRQPEFTQIDVEMSF
CEKKDVINVAETFLKDIFKACGKEIQTPFRQMQYKDAMENYGSDKPDLRFDLKFIDVIDIFAKSNNEIFANIAKDTKKNR
IKAIRVPKGDTIFSKRQMQRFEEFVRKFGAEGLAFIQVKEDGLKGPLCKFFSEEDLNELSKRCKLEVGDVVFFGAGAKKT
VLDYMGRFRIFLANELNLIDPNALEFLWVVDFPMFEQNDDGSYSAMHHPFTMPKNIDENDLEEISSIAYDVVLNGVELGG
GSIRIHKNDIQQKVFKLLNIDEEQQKEKFGFLLDALSFGAPPHGGIAIGLDRLIMLVTGANSIREVIAFPKTQRAQCLMT
EAPSPASNEAMRELGIKLRENIK

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=595, Percent_Identity=40, Blast_Score=404, Evalue=1e-112,
Organism=Homo sapiens, GI45439306, Length=306, Percent_Identity=28.4313725490196, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI194272210, Length=256, Percent_Identity=26.953125, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI5031815, Length=256, Percent_Identity=26.953125, Blast_Score=86, Evalue=9e-17,
Organism=Escherichia coli, GI1788173, Length=587, Percent_Identity=51.4480408858603, Blast_Score=597, Evalue=1e-172,
Organism=Escherichia coli, GI1789256, Length=280, Percent_Identity=26.7857142857143, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790571, Length=295, Percent_Identity=25.7627118644068, Blast_Score=93, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI32566633, Length=606, Percent_Identity=36.1386138613861, Blast_Score=330, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI71994340, Length=256, Percent_Identity=26.953125, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17535925, Length=256, Percent_Identity=26.953125, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17535927, Length=256, Percent_Identity=26.953125, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17551876, Length=334, Percent_Identity=25.4491017964072, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325153, Length=645, Percent_Identity=33.1782945736434, Blast_Score=271, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6323011, Length=333, Percent_Identity=26.4264264264264, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321807, Length=292, Percent_Identity=28.0821917808219, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320242, Length=258, Percent_Identity=24.8062015503876, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584738, Length=598, Percent_Identity=39.1304347826087, Blast_Score=387, Evalue=1e-108,
Organism=Drosophila melanogaster, GI17136276, Length=282, Percent_Identity=28.0141843971631, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24640849, Length=258, Percent_Identity=28.6821705426357, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640851, Length=258, Percent_Identity=28.6821705426357, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19921528, Length=290, Percent_Identity=26.8965517241379, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 66162; Mature: 66162

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHYNIDLGISHVGQSVKLCGWVNSYRDHGGVIFIDLRDRSGIIQLVCDPNDSKEAHEI
CCCCEEEEEEHHHCCCCCEEHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHH
ASNARNEFVLIAEGTIRPRGEGLVNPKLKTGEIEVVVSKLTIENESIVPPFAIADESVNE
HHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEECCCCCCH
ELRLKYRFLDLRNPKLYENFALRSKACIAARNSLANMGFLEVETPILTKATPEGARDYLV
HHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEECCCCCCCCCCCC
PSRVHQGEFYALPQSPQLFKQLLMCSGFDRYFQIAKCFRDEDLRADRQPEFTQIDVEMSF
CCCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHH
CEKKDVINVAETFLKDIFKACGKEIQTPFRQMQYKDAMENYGSDKPDLRFDLKFIDVIDI
HCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHH
FAKSNNEIFANIAKDTKKNRIKAIRVPKGDTIFSKRQMQRFEEFVRKFGAEGLAFIQVKE
HHCCCCCEEEEEHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
DGLKGPLCKFFSEEDLNELSKRCKLEVGDVVFFGAGAKKTVLDYMGRFRIFLANELNLID
CCCCCHHHHHCCCCHHHHHHHHCCEEECCEEEECCCCHHHHHHHHCCEEEEEECCCCCCC
PNALEFLWVVDFPMFEQNDDGSYSAMHHPFTMPKNIDENDLEEISSIAYDVVLNGVELGG
CCCEEEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECC
GSIRIHKNDIQQKVFKLLNIDEEQQKEKFGFLLDALSFGAPPHGGIAIGLDRLIMLVTGA
CEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHEEEEECC
NSIREVIAFPKTQRAQCLMTEAPSPASNEAMRELGIKLRENIK
HHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHCHHHHHCCC
>Mature Secondary Structure
MRSHYNIDLGISHVGQSVKLCGWVNSYRDHGGVIFIDLRDRSGIIQLVCDPNDSKEAHEI
CCCCEEEEEEHHHCCCCCEEHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHH
ASNARNEFVLIAEGTIRPRGEGLVNPKLKTGEIEVVVSKLTIENESIVPPFAIADESVNE
HHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEECCCCCCH
ELRLKYRFLDLRNPKLYENFALRSKACIAARNSLANMGFLEVETPILTKATPEGARDYLV
HHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEECCCCCCCCCCCC
PSRVHQGEFYALPQSPQLFKQLLMCSGFDRYFQIAKCFRDEDLRADRQPEFTQIDVEMSF
CCCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHH
CEKKDVINVAETFLKDIFKACGKEIQTPFRQMQYKDAMENYGSDKPDLRFDLKFIDVIDI
HCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHH
FAKSNNEIFANIAKDTKKNRIKAIRVPKGDTIFSKRQMQRFEEFVRKFGAEGLAFIQVKE
HHCCCCCEEEEEHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
DGLKGPLCKFFSEEDLNELSKRCKLEVGDVVFFGAGAKKTVLDYMGRFRIFLANELNLID
CCCCCHHHHHCCCCHHHHHHHHCCEEECCEEEECCCCHHHHHHHHCCEEEEEECCCCCCC
PNALEFLWVVDFPMFEQNDDGSYSAMHHPFTMPKNIDENDLEEISSIAYDVVLNGVELGG
CCCEEEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECC
GSIRIHKNDIQQKVFKLLNIDEEQQKEKFGFLLDALSFGAPPHGGIAIGLDRLIMLVTGA
CEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHEEEEECC
NSIREVIAFPKTQRAQCLMTEAPSPASNEAMRELGIKLRENIK
HHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA