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The map label for this gene is yhdH [H]

Identifier: 153951231

GI number: 153951231

Start: 779589

End: 780929

Strand: Direct

Name: yhdH [H]

Synonym: JJD26997_0880

Alternate gene names: 153951231

Gene position: 779589-780929 (Clockwise)

Preceding gene: 153951915

Following gene: 153952195

Centisome position: 42.25

GC content: 27.44

Gene sequence:

>1341_bases
ATGAGAGCATATTTTTCAAAAATCGGTTTTGTATTGGTTGTTGCTGGTGGAGCCGTTGGTTTGGGTAATGCTTGGAAATT
TCCAACTTTAAGCGCAGAAAATGGTGGTTTTGTTTTTGTGCTTTTATATTTGTTTTTTACTTTAACCATAGGATTTAGTA
TTTTTTTGGCTGAAGTGACTATGGGACGTTTAAGTAAAAGTGATCTTGCAAATGCTTATTCAAATCTTGCCATAAAATAT
GGCAATAGATGGCGATATGGCGGCGTTTTTATGTTAGGTGGTATTTTTGTCCTCTCTTTTTATCTAGTTATCATGGGATG
GGTTTTAAAATATACTGTAGTTAGTCTTTATTATCTTCCTAAAACTTTAGATGAAGCAGCAAGTAATTTTCAGAATTTAA
TTACTACAAATTTGACAAGTTCTGTTTTTTTCTTCACTTTATCTTTTTTTCTTACTTTATTAGTAGTATCTAAAGGTTTA
ATCAAAGGGATTGAAAAATTAAATGTTGTTATAATGCCTAGCTTATTTTTAATGCTTGTTTTTATGTTGTTTTATTGCAT
GGGATTTAAGCAAGGTTTTGCAAATGCTTTTTCTTATTTATTTTATCCTGATTTTTCACATTTTAAATTTAGCTCTATTG
CCGAAGCTTTAGGGCTTGCATTTTTTACCTTATGCTTGGGAATAGGTTGTATAGTTACATATTCATCAGCCTTAGATAAA
AAAACAAATTTTATAAAAAGTTCAGTGTATATTGTTTTGATTAATTTATTGATTTCTTTTATTATGGGACTTATTGTTTT
TACTTTTATTTTTGAATTTGGAGCCGATCCGCATACTCAAGGAGTGGGAATTGTTTTTGTATCCTTGATGAGTTTGTTCA
ATCAACTTGGAGCTTTAGGCTATATTTTTGCATTTTGTTTTTTCTTAGCACTTTTTTTTGCTGGTATTACTTCAGCTGTT
TCAATGATAGAGCCTTTAACTTTTTATATGATCAATAACTATCAAATTTCTCGCGCTAAAGCTCTATTTTTCATAGGTTT
ATTTGTTTTTGTTTTTGGAATTTGTTGTATTTTGTCGTTAAATTTAAATTTTTTTTCTATGTTTAGTTTTTTTGGTAAAG
ATTTTTTTACTTTATTAGATAAATTAACTTCAAATTTTTTACTTCCACTTGGTGCCATAGTATGCTCTATATTTGTAGGT
TTTTTTATGAATAAAAAACAAATTTATAAAATTTTTTCTAAATTTATAAGTCGAAAAATTTTCTTAATTTGGTTGTTTTT
TATTCGTTTTATATCGCCTATAGCAATAATTTTGGTAATGTGTTATCAAATTTTTGTATAA

Upstream 100 bases:

>100_bases
TATATTTTTTGAACTTTGGTATGTATTTTTGAGATTTATTTCCCCTTTGGCTGTTGTTATAGTTATGATAGCTGCTTTTT
TAAAGTGAGTTTGAAAAATA

Downstream 100 bases:

>100_bases
TCAATGAAAAAATATTTTTTTAAGGAAAAATAATGGCTAAAAAATTCATCGATGTAATGGATACAAGCTTTAGGGATGGT
TTTCAGTCTGTTTACGGGGC

Product: putative sodium transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MRAYFSKIGFVLVVAGGAVGLGNAWKFPTLSAENGGFVFVLLYLFFTLTIGFSIFLAEVTMGRLSKSDLANAYSNLAIKY
GNRWRYGGVFMLGGIFVLSFYLVIMGWVLKYTVVSLYYLPKTLDEAASNFQNLITTNLTSSVFFFTLSFFLTLLVVSKGL
IKGIEKLNVVIMPSLFLMLVFMLFYCMGFKQGFANAFSYLFYPDFSHFKFSSIAEALGLAFFTLCLGIGCIVTYSSALDK
KTNFIKSSVYIVLINLLISFIMGLIVFTFIFEFGADPHTQGVGIVFVSLMSLFNQLGALGYIFAFCFFLALFFAGITSAV
SMIEPLTFYMINNYQISRAKALFFIGLFVFVFGICCILSLNLNFFSMFSFFGKDFFTLLDKLTSNFLLPLGAIVCSIFVG
FFMNKKQIYKIFSKFISRKIFLIWLFFIRFISPIAIILVMCYQIFV

Sequences:

>Translated_446_residues
MRAYFSKIGFVLVVAGGAVGLGNAWKFPTLSAENGGFVFVLLYLFFTLTIGFSIFLAEVTMGRLSKSDLANAYSNLAIKY
GNRWRYGGVFMLGGIFVLSFYLVIMGWVLKYTVVSLYYLPKTLDEAASNFQNLITTNLTSSVFFFTLSFFLTLLVVSKGL
IKGIEKLNVVIMPSLFLMLVFMLFYCMGFKQGFANAFSYLFYPDFSHFKFSSIAEALGLAFFTLCLGIGCIVTYSSALDK
KTNFIKSSVYIVLINLLISFIMGLIVFTFIFEFGADPHTQGVGIVFVSLMSLFNQLGALGYIFAFCFFLALFFAGITSAV
SMIEPLTFYMINNYQISRAKALFFIGLFVFVFGICCILSLNLNFFSMFSFFGKDFFTLLDKLTSNFLLPLGAIVCSIFVG
FFMNKKQIYKIFSKFISRKIFLIWLFFIRFISPIAIILVMCYQIFV
>Mature_446_residues
MRAYFSKIGFVLVVAGGAVGLGNAWKFPTLSAENGGFVFVLLYLFFTLTIGFSIFLAEVTMGRLSKSDLANAYSNLAIKY
GNRWRYGGVFMLGGIFVLSFYLVIMGWVLKYTVVSLYYLPKTLDEAASNFQNLITTNLTSSVFFFTLSFFLTLLVVSKGL
IKGIEKLNVVIMPSLFLMLVFMLFYCMGFKQGFANAFSYLFYPDFSHFKFSSIAEALGLAFFTLCLGIGCIVTYSSALDK
KTNFIKSSVYIVLINLLISFIMGLIVFTFIFEFGADPHTQGVGIVFVSLMSLFNQLGALGYIFAFCFFLALFFAGITSAV
SMIEPLTFYMINNYQISRAKALFFIGLFVFVFGICCILSLNLNFFSMFSFFGKDFFTLLDKLTSNFLLPLGAIVCSIFVG
FFMNKKQIYKIFSKFISRKIFLIWLFFIRFISPIAIILVMCYQIFV

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507041, Length=489, Percent_Identity=23.721881390593, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI188528618, Length=488, Percent_Identity=22.5409836065574, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI21361581, Length=430, Percent_Identity=23.0232558139535, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI33354281, Length=305, Percent_Identity=25.5737704918033, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI289191351, Length=498, Percent_Identity=22.4899598393574, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4557046, Length=498, Percent_Identity=22.4899598393574, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI289191377, Length=498, Percent_Identity=22.4899598393574, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17554804, Length=480, Percent_Identity=21.0416666666667, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24652942, Length=358, Percent_Identity=24.5810055865922, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45551088, Length=358, Percent_Identity=24.5810055865922, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19921936, Length=372, Percent_Identity=23.6559139784946, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 50346; Mature: 50346

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRAYFSKIGFVLVVAGGAVGLGNAWKFPTLSAENGGFVFVLLYLFFTLTIGFSIFLAEVT
CCCHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MGRLSKSDLANAYSNLAIKYGNRWRYGGVFMLGGIFVLSFYLVIMGWVLKYTVVSLYYLP
HHHCCHHHHHHHHHHHEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTLDEAASNFQNLITTNLTSSVFFFTLSFFLTLLVVSKGLIKGIEKLNVVIMPSLFLMLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMLFYCMGFKQGFANAFSYLFYPDFSHFKFSSIAEALGLAFFTLCLGIGCIVTYSSALDK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTNFIKSSVYIVLINLLISFIMGLIVFTFIFEFGADPHTQGVGIVFVSLMSLFNQLGALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
YIFAFCFFLALFFAGITSAVSMIEPLTFYMINNYQISRAKALFFIGLFVFVFGICCILSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHC
NLNFFSMFSFFGKDFFTLLDKLTSNFLLPLGAIVCSIFVGFFMNKKQIYKIFSKFISRKI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
FLIWLFFIRFISPIAIILVMCYQIFV
HHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]