Click here to switch to the map view.

The map label for this gene is ykkD [H]

Identifier: 153951026

GI number: 153951026

Start: 1464730

End: 1465044

Strand: Direct

Name: ykkD [H]

Synonym: JJD26997_1656

Alternate gene names: 153951026

Gene position: 1464730-1465044 (Clockwise)

Preceding gene: 153951921

Following gene: 153952444

Centisome position: 79.38

GC content: 31.43

Gene sequence:

>315_bases
ATGGAATGGTTTTATTTGTTTTTAGCTACCGCTTGTGAAATTTTTGGCGTGGTGATCATGAAAAAACTTGTAAGCACTAA
AAATAAGCTTTACCTTTTGGCTTTGATTGTATGCTTTGGATTTTCTTTTACTTTTTTAAGCTTAAGTATGCAAAATATCG
CTATGAGTGTTGCTTATGCTATATGGACAGGAGCTGGAACCGCTGGTGGAGTAATGATAGGAGTGCTTTTTTATAAAGAA
AGTAAAAGTTTTTTAAAACTTTTTTTAATCGCTGTGATTATTGCTTGTACGGTAAGTTTAAAATTTCTTTCTTAA

Upstream 100 bases:

>100_bases
TTTATTTTTAACGAAGCTGTTTCTATAGTTAAACTTGTGCTTATAGCGATTTTACTTTTAAGCATTATAGCCCTTAAATG
GGTAAGTAAGAAAGCTTAAT

Downstream 100 bases:

>100_bases
GGATTTTTTGTGCAAATTTATGTAGGTGGAATACATACTAATGTAGGAAAAACACATTTTTGTGCGAATTTTTGTGCGAA
TTTTAACTATGATTATTTTA

Product: SMR family multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MEWFYLFLATACEIFGVVIMKKLVSTKNKLYLLALIVCFGFSFTFLSLSMQNIAMSVAYAIWTGAGTAGGVMIGVLFYKE
SKSFLKLFLIAVIIACTVSLKFLS

Sequences:

>Translated_104_residues
MEWFYLFLATACEIFGVVIMKKLVSTKNKLYLLALIVCFGFSFTFLSLSMQNIAMSVAYAIWTGAGTAGGVMIGVLFYKE
SKSFLKLFLIAVIIACTVSLKFLS
>Mature_104_residues
MEWFYLFLATACEIFGVVIMKKLVSTKNKLYLLALIVCFGFSFTFLSLSMQNIAMSVAYAIWTGAGTAGGVMIGVLFYKE
SKSFLKLFLIAVIIACTVSLKFLS

Specific function: Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. YkkC/ykkD (TC 2.A.7.1.5) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11505; Mature: 11505

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWFYLFLATACEIFGVVIMKKLVSTKNKLYLLALIVCFGFSFTFLSLSMQNIAMSVAYA
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWTGAGTAGGVMIGVLFYKESKSFLKLFLIAVIIACTVSLKFLS
HHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWFYLFLATACEIFGVVIMKKLVSTKNKLYLLALIVCFGFSFTFLSLSMQNIAMSVAYA
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWTGAGTAGGVMIGVLFYKESKSFLKLFLIAVIIACTVSLKFLS
HHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377 [H]