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The map label for this gene is yeeJ [C]

Identifier: 153950815

GI number: 153950815

Start: 2630391

End: 2633216

Strand: Reverse

Name: yeeJ [C]

Synonym: YpsIP31758_2329

Alternate gene names: 153950815

Gene position: 2633216-2630391 (Counterclockwise)

Preceding gene: 153950066

Following gene: 153948393

Centisome position: 55.75

GC content: 49.26

Gene sequence:

>2826_bases
ATGGCTGGGGCTTCAGAAAAATATGATGCTAACGCACCGCAACAGGTCCAGCCTTATTCTGTCTCTTCATCTGCATTTGA
AAATCTCCATCCTAATAATGAAATGGAGAGTTCAATCAATCCCTTTTCCGCATCGGATACAGAAAGAAATGCTGCAATAA
TAGATCGCGCCAATAAGGAGCAGGAGACTGAAGCGGTGAATAAGATGATAAGCACCGGGGCCAGGTTAGCTGCATCAGGC
AGGGCATCTGATGTTGCTCACTCAATGGTGGGCGATGCGGTTAATCAAGAAATCAAACAGTGGTTAAATCGATTCGGTAC
GGCTCAAGTTAATCTGAATTTTGACAAAAATTTTTCGCTAAAAGAAAGCTCTCTTGATTGGCTGGCTCCTTGGTATGACT
CTGCTTCATTCCTCTTTTTTAGTCAGTTAGGTATTCGCAATAAAGACAGCCGCAACACACTTAACCTTGGCGTCGGGATA
CGTACATTGGAGAACGGTTGGCTGTACGGACTTAATACTTTTTATGATAATGATTTGACCGGCCACAACCACCGTATCGG
TCTTGGTGCCGAGGTCTGGACCGATTATTTACAGTTGGCTGCCAATGGGTATTTTCGCCTCAATGGATGGCACTCGTCGC
GTGATTTCTCCGACTATAAAGAGCGCCCAGCCACTGGGGGGGATTTGCGCGCGAATGCTTATTTACCTGCACTCCCACAA
CTGGGGGGGAAGTTGATGTATGAGCAATACACCGGTGAACGTGTTGCTTTATTTGGCAAAGATAATCTGCAACGCAACCC
TTATGCCGTGACTGCCGGGATCAATTACACCCCCGTGCCTCTGCTCACTGTCGGGGTAGATCAGCGTATGGGGAAAAGCA
GTAAGCATGAAACACAGTGGAACCTCCAAATGAACTATCGCCTGGGCGAGAGTTTTCAGTCGCAACTTAGCCCTTCAGCG
GTGGCAGGAACACGTCTACTGGCGGAGAGCCGCTATAACCTTGTCGATCGTAACAATAATATCGTGTTGGAGTATCAGAA
ACAGCAGGTGGTTAAACTGACATTATCGCCAGCAACTATCTCCGGCCTGCCGGGTCAGGTTTATCAGGTGAACGCACAAG
TACAAGGGGCATCTGCTGTAAGGGAAATTGTCTGGAGTGATGCCGAACTGATTGCCGCTGGCGGCACATTAACACCACTG
AGTACCACACAATTCAACTTGGTTTTACCGCCTTATAAACGCACAGCACAAGTGAGTCGGGTAACGGACGACCTGACAGC
CAACTTTTATTCGCTTAGTGCGCTCGCGGTTGATCACCAAGGAAACCGATCTAACTCATTCACATTGAGCGTCACCGTTC
AGCAGCCTCAGTTGACATTAACGGCGGCCGTCATTGGTGATGGCGCACCGGCTAATGGGAAAACTGCAATCACCGTTGAG
TTCACCGTTGCTGATTTTGAGGGGAAACCCTTAGCCGGGCAGGAGGTGGTGATAACCACCAATAATGGTGCGCTACCGAA
TAAAATCACGGAAAAGACAGATGCCAACGGCGTCGCGCGCATTGCATTAACCAATACGACAGATGGCGTGACGGTAGTCA
CAGCAGAAGTGGAGGGGCAACGGCAAAGTGTTGATACCCACTTTGTTAAGGGTACTATCGCGGCGGATAAATCCACTCTG
GCTGCGGTACCGACATCTATCATCGCTGATGGTCTAATGGCTTCAACCATCACGTTGGAGTTGAAGGATACCTATGGGGA
CCCGCAGGCTGGCGCGAATGTGGCTTTTGACACAACCTTAGGCAATATGGGCGTTATCACGGATCACAATGACGGCACTT
ATAGCGCACCATTGACCAGTACCACGTTGGGGGTAGCAACAGTAACGGTGAAAGTGGATGGGGCTGCGTTCAGTGTGCCG
AGTGTGACGGTTAATTTCACGGCAGATCCTATTCCAGATGCTGGCCGCTCCAGTTTCACCGTCTCCACACCGGATATCTT
GGCTGATGGCACGATGAGTTCCACATTATCCTTTGTCCCTGTCGATAAGAATGGCCATTTTATCAGTGGGATGCAGGGCT
TGAGTTTTACTCAAAACGGTGTGCCGGTGAGTATTAGCCCCATTACCGAGCAGCCAGATAGCTATACCGCGACGGTGGTT
GGGAATAGTGTCGGTGATGTCACAATCACGCCGCAGGTTGATACCCTGATACTGAGTACATTGCAGAAAAAAATATCCCT
ATTCCCGGTACCTACGCTGACCGGTATTCTGGTTAACGGGCAAAATTTCGCTACGGATAAAGGGTTCCCGAAAACGATCT
TTAAAAACGCCACATTCCAGTTACAGATGGATAACGATGTTGCTAATAATACTCAGTATGAGTGGTCGTCGTCATTCACA
CCCAATGTATCGGTTAACGATCAGGGTCAGGTGACGATTACCTACCAAACCTATAGCGAAGTGGCTGTGACGGCGAAAAG
TAAAAAATTCCCAAGTTATTCGGTGAGTTATCGGTTCTACCCAAATCGGTGGATATACGATGGCGGCAGATCGCTGGTAT
CCAGTCTCGAGGCCAGCAGACAATGCCAAGGTTCAGATATGTCTGCGGTTCTTGAATCCTCACGTGCAACCAACGGAACG
CGTGCGCCTGACGGGACATTGTGGGGCGAGTGGGGGAGCTTGACCGCGTATAGTTCTGATTGGCAATCTGGTGAATATTG
GGTCAAAAAGACCAGCACGGATTTTGAAACCATGAATATGGACACAGGCGCACTGCAACCAGGGCCTGCATACTTGGCGT
TCCCGCTCTGTGCGCTGTCAATATAA

Upstream 100 bases:

>100_bases
GATAAGGAATGCGGGAATGTCTATGTATTTTAATAAAATAATTTCATTTAATATTATTTCACGAATAGTTATTTGTATCT
TTTTGATATGTGGAATGTTC

Downstream 100 bases:

>100_bases
CCAGATAACAGATAGCAATAAGAACAGTTTAATGAGCTGATTATTTGGGGCGCGAATGGGAGTCCGGCAATCCTAGACTC
GCCCCATAAGTAGCAAACGT

Product: invasin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 941; Mature: 940

Protein sequence:

>941_residues
MAGASEKYDANAPQQVQPYSVSSSAFENLHPNNEMESSINPFSASDTERNAAIIDRANKEQETEAVNKMISTGARLAASG
RASDVAHSMVGDAVNQEIKQWLNRFGTAQVNLNFDKNFSLKESSLDWLAPWYDSASFLFFSQLGIRNKDSRNTLNLGVGI
RTLENGWLYGLNTFYDNDLTGHNHRIGLGAEVWTDYLQLAANGYFRLNGWHSSRDFSDYKERPATGGDLRANAYLPALPQ
LGGKLMYEQYTGERVALFGKDNLQRNPYAVTAGINYTPVPLLTVGVDQRMGKSSKHETQWNLQMNYRLGESFQSQLSPSA
VAGTRLLAESRYNLVDRNNNIVLEYQKQQVVKLTLSPATISGLPGQVYQVNAQVQGASAVREIVWSDAELIAAGGTLTPL
STTQFNLVLPPYKRTAQVSRVTDDLTANFYSLSALAVDHQGNRSNSFTLSVTVQQPQLTLTAAVIGDGAPANGKTAITVE
FTVADFEGKPLAGQEVVITTNNGALPNKITEKTDANGVARIALTNTTDGVTVVTAEVEGQRQSVDTHFVKGTIAADKSTL
AAVPTSIIADGLMASTITLELKDTYGDPQAGANVAFDTTLGNMGVITDHNDGTYSAPLTSTTLGVATVTVKVDGAAFSVP
SVTVNFTADPIPDAGRSSFTVSTPDILADGTMSSTLSFVPVDKNGHFISGMQGLSFTQNGVPVSISPITEQPDSYTATVV
GNSVGDVTITPQVDTLILSTLQKKISLFPVPTLTGILVNGQNFATDKGFPKTIFKNATFQLQMDNDVANNTQYEWSSSFT
PNVSVNDQGQVTITYQTYSEVAVTAKSKKFPSYSVSYRFYPNRWIYDGGRSLVSSLEASRQCQGSDMSAVLESSRATNGT
RAPDGTLWGEWGSLTAYSSDWQSGEYWVKKTSTDFETMNMDTGALQPGPAYLAFPLCALSI

Sequences:

>Translated_941_residues
MAGASEKYDANAPQQVQPYSVSSSAFENLHPNNEMESSINPFSASDTERNAAIIDRANKEQETEAVNKMISTGARLAASG
RASDVAHSMVGDAVNQEIKQWLNRFGTAQVNLNFDKNFSLKESSLDWLAPWYDSASFLFFSQLGIRNKDSRNTLNLGVGI
RTLENGWLYGLNTFYDNDLTGHNHRIGLGAEVWTDYLQLAANGYFRLNGWHSSRDFSDYKERPATGGDLRANAYLPALPQ
LGGKLMYEQYTGERVALFGKDNLQRNPYAVTAGINYTPVPLLTVGVDQRMGKSSKHETQWNLQMNYRLGESFQSQLSPSA
VAGTRLLAESRYNLVDRNNNIVLEYQKQQVVKLTLSPATISGLPGQVYQVNAQVQGASAVREIVWSDAELIAAGGTLTPL
STTQFNLVLPPYKRTAQVSRVTDDLTANFYSLSALAVDHQGNRSNSFTLSVTVQQPQLTLTAAVIGDGAPANGKTAITVE
FTVADFEGKPLAGQEVVITTNNGALPNKITEKTDANGVARIALTNTTDGVTVVTAEVEGQRQSVDTHFVKGTIAADKSTL
AAVPTSIIADGLMASTITLELKDTYGDPQAGANVAFDTTLGNMGVITDHNDGTYSAPLTSTTLGVATVTVKVDGAAFSVP
SVTVNFTADPIPDAGRSSFTVSTPDILADGTMSSTLSFVPVDKNGHFISGMQGLSFTQNGVPVSISPITEQPDSYTATVV
GNSVGDVTITPQVDTLILSTLQKKISLFPVPTLTGILVNGQNFATDKGFPKTIFKNATFQLQMDNDVANNTQYEWSSSFT
PNVSVNDQGQVTITYQTYSEVAVTAKSKKFPSYSVSYRFYPNRWIYDGGRSLVSSLEASRQCQGSDMSAVLESSRATNGT
RAPDGTLWGEWGSLTAYSSDWQSGEYWVKKTSTDFETMNMDTGALQPGPAYLAFPLCALSI
>Mature_940_residues
AGASEKYDANAPQQVQPYSVSSSAFENLHPNNEMESSINPFSASDTERNAAIIDRANKEQETEAVNKMISTGARLAASGR
ASDVAHSMVGDAVNQEIKQWLNRFGTAQVNLNFDKNFSLKESSLDWLAPWYDSASFLFFSQLGIRNKDSRNTLNLGVGIR
TLENGWLYGLNTFYDNDLTGHNHRIGLGAEVWTDYLQLAANGYFRLNGWHSSRDFSDYKERPATGGDLRANAYLPALPQL
GGKLMYEQYTGERVALFGKDNLQRNPYAVTAGINYTPVPLLTVGVDQRMGKSSKHETQWNLQMNYRLGESFQSQLSPSAV
AGTRLLAESRYNLVDRNNNIVLEYQKQQVVKLTLSPATISGLPGQVYQVNAQVQGASAVREIVWSDAELIAAGGTLTPLS
TTQFNLVLPPYKRTAQVSRVTDDLTANFYSLSALAVDHQGNRSNSFTLSVTVQQPQLTLTAAVIGDGAPANGKTAITVEF
TVADFEGKPLAGQEVVITTNNGALPNKITEKTDANGVARIALTNTTDGVTVVTAEVEGQRQSVDTHFVKGTIAADKSTLA
AVPTSIIADGLMASTITLELKDTYGDPQAGANVAFDTTLGNMGVITDHNDGTYSAPLTSTTLGVATVTVKVDGAAFSVPS
VTVNFTADPIPDAGRSSFTVSTPDILADGTMSSTLSFVPVDKNGHFISGMQGLSFTQNGVPVSISPITEQPDSYTATVVG
NSVGDVTITPQVDTLILSTLQKKISLFPVPTLTGILVNGQNFATDKGFPKTIFKNATFQLQMDNDVANNTQYEWSSSFTP
NVSVNDQGQVTITYQTYSEVAVTAKSKKFPSYSVSYRFYPNRWIYDGGRSLVSSLEASRQCQGSDMSAVLESSRATNGTR
APDGTLWGEWGSLTAYSSDWQSGEYWVKKTSTDFETMNMDTGALQPGPAYLAFPLCALSI

Specific function: Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 Big-1 (bacterial Ig-like domain 1) domains [H]

Homologues:

Organism=Escherichia coli, GI145693153, Length=444, Percent_Identity=40.3153153153153, Blast_Score=322, Evalue=1e-88,
Organism=Escherichia coli, GI145693120, Length=398, Percent_Identity=32.1608040201005, Blast_Score=196, Evalue=5e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR016186
- InterPro:   IPR016187
- InterPro:   IPR003535
- InterPro:   IPR013117
- InterPro:   IPR008964
- InterPro:   IPR015217 [H]

Pfam domain/function: PF02369 Big_1; PF07979 Intimin_C; PF09134 Invasin_D3 [H]

EC number: NA

Molecular weight: Translated: 101539; Mature: 101408

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS51127 BIG1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGASEKYDANAPQQVQPYSVSSSAFENLHPNNEMESSINPFSASDTERNAAIIDRANKE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEEEECCCCH
QETEAVNKMISTGARLAASGRASDVAHSMVGDAVNQEIKQWLNRFGTAQVNLNFDKNFSL
HHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCC
KESSLDWLAPWYDSASFLFFSQLGIRNKDSRNTLNLGVGIRTLENGWLYGLNTFYDNDLT
CCCCCCEEECCCCCCCEEEEHHCCCCCCCCCCEEEEEEEEEEECCCEEEEEHEEECCCCC
GHNHRIGLGAEVWTDYLQLAANGYFRLNGWHSSRDFSDYKERPATGGDLRANAYLPALPQ
CCCEEEECCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCCCCCCEEECCCCCCCHH
LGGKLMYEQYTGERVALFGKDNLQRNPYAVTAGINYTPVPLLTVGVDQRMGKSSKHETQW
CCCEEEEEECCCCEEEEEECCCCCCCCEEEECCCCCCCCEEEEECCHHHCCCCCCCCEEE
NLQMNYRLGESFQSQLSPSAVAGTRLLAESRYNLVDRNNNIVLEYQKQQVVKLTLSPATI
EEEEEEEECHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCEEEEECCCEEEEEEECCCEE
SGLPGQVYQVNAQVQGASAVREIVWSDAELIAAGGTLTPLSTTQFNLVLPPYKRTAQVSR
CCCCCCEEEEEEEECCHHHHHHHHCCCCEEEEECCEECCCCCCEEEEEECCCHHHHHHHH
VTDDLTANFYSLSALAVDHQGNRSNSFTLSVTVQQPQLTLTAAVIGDGAPANGKTAITVE
HHHHHHCCEEEEEEEEEECCCCCCCEEEEEEEEECCCEEEEEEEECCCCCCCCCEEEEEE
FTVADFEGKPLAGQEVVITTNNGALPNKITEKTDANGVARIALTNTTDGVTVVTAEVEGQ
EEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEECCC
RQSVDTHFVKGTIAADKSTLAAVPTSIIADGLMASTITLELKDTYGDPQAGANVAFDTTL
CCCCCEEEEEEEEECCCCHHHHCCHHHHHCCCEEEEEEEEEECCCCCCCCCCEEEEEECC
GNMGVITDHNDGTYSAPLTSTTLGVATVTVKVDGAAFSVPSVTVNFTADPIPDAGRSSFT
CCEEEEEECCCCEEECCCCCCEEEEEEEEEEECCCEEECCEEEEEEECCCCCCCCCCCEE
VSTPDILADGTMSSTLSFVPVDKNGHFISGMQGLSFTQNGVPVSISPITEQPDSYTATVV
ECCCCCEECCCHHCCEEEEEECCCCCEEECCCCCCEECCCCCEEEECCCCCCCCEEEEEE
GNSVGDVTITPQVDTLILSTLQKKISLFPVPTLTGILVNGQNFATDKGFPKTIFKNATFQ
CCCCCCEEECCCHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCCCHHHHCCCEEE
LQMDNDVANNTQYEWSSSFTPNVSVNDQGQVTITYQTYSEVAVTAKSKKFPSYSVSYRFY
EEECCCCCCCCCEEECCCCCCCEEECCCCCEEEEEEECCEEEEEECCCCCCCEEEEEEEC
PNRWIYDGGRSLVSSLEASRQCQGSDMSAVLESSRATNGTRAPDGTLWGEWGSLTAYSSD
CCCEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCEEEECCC
WQSGEYWVKKTSTDFETMNMDTGALQPGPAYLAFPLCALSI
CCCCCEEEEECCCCCEEEECCCCCCCCCCCHHEEHHHHHCC
>Mature Secondary Structure 
AGASEKYDANAPQQVQPYSVSSSAFENLHPNNEMESSINPFSASDTERNAAIIDRANKE
CCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEEEECCCCH
QETEAVNKMISTGARLAASGRASDVAHSMVGDAVNQEIKQWLNRFGTAQVNLNFDKNFSL
HHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCC
KESSLDWLAPWYDSASFLFFSQLGIRNKDSRNTLNLGVGIRTLENGWLYGLNTFYDNDLT
CCCCCCEEECCCCCCCEEEEHHCCCCCCCCCCEEEEEEEEEEECCCEEEEEHEEECCCCC
GHNHRIGLGAEVWTDYLQLAANGYFRLNGWHSSRDFSDYKERPATGGDLRANAYLPALPQ
CCCEEEECCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCCCCCCEEECCCCCCCHH
LGGKLMYEQYTGERVALFGKDNLQRNPYAVTAGINYTPVPLLTVGVDQRMGKSSKHETQW
CCCEEEEEECCCCEEEEEECCCCCCCCEEEECCCCCCCCEEEEECCHHHCCCCCCCCEEE
NLQMNYRLGESFQSQLSPSAVAGTRLLAESRYNLVDRNNNIVLEYQKQQVVKLTLSPATI
EEEEEEEECHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCEEEEECCCEEEEEEECCCEE
SGLPGQVYQVNAQVQGASAVREIVWSDAELIAAGGTLTPLSTTQFNLVLPPYKRTAQVSR
CCCCCCEEEEEEEECCHHHHHHHHCCCCEEEEECCEECCCCCCEEEEEECCCHHHHHHHH
VTDDLTANFYSLSALAVDHQGNRSNSFTLSVTVQQPQLTLTAAVIGDGAPANGKTAITVE
HHHHHHCCEEEEEEEEEECCCCCCCEEEEEEEEECCCEEEEEEEECCCCCCCCCEEEEEE
FTVADFEGKPLAGQEVVITTNNGALPNKITEKTDANGVARIALTNTTDGVTVVTAEVEGQ
EEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEECCC
RQSVDTHFVKGTIAADKSTLAAVPTSIIADGLMASTITLELKDTYGDPQAGANVAFDTTL
CCCCCEEEEEEEEECCCCHHHHCCHHHHHCCCEEEEEEEEEECCCCCCCCCCEEEEEECC
GNMGVITDHNDGTYSAPLTSTTLGVATVTVKVDGAAFSVPSVTVNFTADPIPDAGRSSFT
CCEEEEEECCCCEEECCCCCCEEEEEEEEEEECCCEEECCEEEEEEECCCCCCCCCCCEE
VSTPDILADGTMSSTLSFVPVDKNGHFISGMQGLSFTQNGVPVSISPITEQPDSYTATVV
ECCCCCEECCCHHCCEEEEEECCCCCEEECCCCCCEECCCCCEEEECCCCCCCCEEEEEE
GNSVGDVTITPQVDTLILSTLQKKISLFPVPTLTGILVNGQNFATDKGFPKTIFKNATFQ
CCCCCCEEECCCHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCCCHHHHCCCEEE
LQMDNDVANNTQYEWSSSFTPNVSVNDQGQVTITYQTYSEVAVTAKSKKFPSYSVSYRFY
EEECCCCCCCCCEEECCCCCCCEEECCCCCEEEEEEECCEEEEEECCCCCCCEEEEEEEC
PNRWIYDGGRSLVSSLEASRQCQGSDMSAVLESSRATNGTRAPDGTLWGEWGSLTAYSSD
CCCEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCEEEECCC
WQSGEYWVKKTSTDFETMNMDTGALQPGPAYLAFPLCALSI
CCCCCEEEEECCCCCEEEECCCCCCCCCCCHHEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3304658; 1693333; 10514372 [H]