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The map label for this gene is lsrR [H]

Identifier: 153949683

GI number: 153949683

Start: 3973503

End: 3974423

Strand: Reverse

Name: lsrR [H]

Synonym: YpsIP31758_3519

Alternate gene names: 153949683

Gene position: 3974423-3973503 (Counterclockwise)

Preceding gene: 153949115

Following gene: 153948237

Centisome position: 84.14

GC content: 52.33

Gene sequence:

>921_bases
ATGAGTGAAGAGGAACTGCTCGCTCGCGTTGCGTGGTTTTATTATCACGATGGTTTAACACAAGGGGATATTGGTGAGTT
GCTGGGGCTGGCTCGGCTTAAAGTCTCCCGGTTATTGGAGAAAGGCCGGCAGTCTGGGGTGATCCGCGTCCAGATTAATT
CGCGCTATGAAGGCTGTCTGGAACTGGAAAATACCCTGCAACAGCATTTTGGCCTGAAGCATATCCGCATTCTGCCGTCT
TTGGCCTCCCTCAGTATCAGTAGCCGGTTGGGTATTGGTGCCGCCCATTTATTAATGGCGCTGATACAACCACAACAACT
TTTGGCCGTTGGTTTCGGTGAGACCACCATGTGCGCCTTGCAACATTTGAGTGGTTTTATCGCATCACAGCAGGTCCGTT
TAGTCACGTTATCCGGCGGTGTCGGCTCCTATATGACGGGGATTGGTCAGTTGGATGCGGCCTGCCAGGTCAGTATCATT
CCGGCCCCGCTGCGTGCCTCAAATGCCCATGTTGCCGACACGTTTCGCCAGGAAAACAGCGTCCGAGATGTGATGCTAGC
CGCCTGCGCGGCAGATATTGCGGTCGTTGGGATCGGTTCGGTTAATCAGCAAAAAGAAGCCACAATTTTGCGTTCGGGCT
ATATCAGCGAAGGTGAGCAACTGATGTTTAGCCGTAAAGGCGCGGTTGGGGATATCCTCGGTTACTTTATCCAAGCCGAT
GGCGCGTTGGTGCCAGATATGCAGATTCATCAGGAGTTGATTGGTATTTCGTTGGCTGATTTAACCACCATCCCAACCGT
GATTGGTGTTGCAGGGGGGGTAGAAAAAGCGGATGTGATTGTCGCAGCGCTGCGGGGGAGGTATGTGAATGCGTTGGTGA
CGGATGAGGTGACGGCGCGTGCAATCATTAACTTACTTTAA

Upstream 100 bases:

>100_bases
AGCGGCAATAAGAGAACAATCGGCAATGATGAAAGAAAAACCAGCAGTAAAAGAAAAACCCCTGTCGTCCAACGACGAAT
ACAAATATCCGGGTAATAGC

Downstream 100 bases:

>100_bases
TTGGGTGATTGGCTATTTCACTTGCCAGTTTGAGATTGGGCAGTGCTCGTGACCGTCACAGACTGTGTGTAGGCTCCGAT
CTCTGCGCGCGGTCCCACAG

Product: Crp/Fnr family sugar-binding transcriptional regulatory

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSEEELLARVAWFYYHDGLTQGDIGELLGLARLKVSRLLEKGRQSGVIRVQINSRYEGCLELENTLQQHFGLKHIRILPS
LASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLVTLSGGVGSYMTGIGQLDAACQVSII
PAPLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGSVNQQKEATILRSGYISEGEQLMFSRKGAVGDILGYFIQAD
GALVPDMQIHQELIGISLADLTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTDEVTARAIINLL

Sequences:

>Translated_306_residues
MSEEELLARVAWFYYHDGLTQGDIGELLGLARLKVSRLLEKGRQSGVIRVQINSRYEGCLELENTLQQHFGLKHIRILPS
LASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLVTLSGGVGSYMTGIGQLDAACQVSII
PAPLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGSVNQQKEATILRSGYISEGEQLMFSRKGAVGDILGYFIQAD
GALVPDMQIHQELIGISLADLTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTDEVTARAIINLL
>Mature_305_residues
SEEELLARVAWFYYHDGLTQGDIGELLGLARLKVSRLLEKGRQSGVIRVQINSRYEGCLELENTLQQHFGLKHIRILPSL
ASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLVTLSGGVGSYMTGIGQLDAACQVSIIP
APLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGSVNQQKEATILRSGYISEGEQLMFSRKGAVGDILGYFIQADG
ALVPDMQIHQELIGISLADLTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTDEVTARAIINLL

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI- 2, lsrR is inactivated by binding phospho-AI-2, leading to the trans

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=303, Percent_Identity=67.986798679868, Blast_Score=433, Evalue=1e-123,
Organism=Escherichia coli, GI87082414, Length=314, Percent_Identity=25.796178343949, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 32687; Mature: 32556

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEELLARVAWFYYHDGLTQGDIGELLGLARLKVSRLLEKGRQSGVIRVQINSRYEGCL
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHH
ELENTLQQHFGLKHIRILPSLASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHEEECCCHHHHHHH
QHLSGFIASQQVRLVTLSGGVGSYMTGIGQLDAACQVSIIPAPLRASNAHVADTFRQENS
HHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCH
VRDVMLAACAADIAVVGIGSVNQQKEATILRSGYISEGEQLMFSRKGAVGDILGYFIQAD
HHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHCC
GALVPDMQIHQELIGISLADLTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTDEVTAR
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEHHHHHHHH
AIINLL
HHHHCC
>Mature Secondary Structure 
SEEELLARVAWFYYHDGLTQGDIGELLGLARLKVSRLLEKGRQSGVIRVQINSRYEGCL
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHH
ELENTLQQHFGLKHIRILPSLASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHEEECCCHHHHHHH
QHLSGFIASQQVRLVTLSGGVGSYMTGIGQLDAACQVSIIPAPLRASNAHVADTFRQENS
HHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCH
VRDVMLAACAADIAVVGIGSVNQQKEATILRSGYISEGEQLMFSRKGAVGDILGYFIQAD
HHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHCC
GALVPDMQIHQELIGISLADLTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTDEVTAR
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEHHHHHHHH
AIINLL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]