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The map label for this gene is mtnC

Identifier: 153949004

GI number: 153949004

Start: 3585675

End: 3586364

Strand: Reverse

Name: mtnC

Synonym: YpsIP31758_3181

Alternate gene names: 153949004

Gene position: 3586364-3585675 (Counterclockwise)

Preceding gene: 153949706

Following gene: 153950848

Centisome position: 75.93

GC content: 48.55

Gene sequence:

>690_bases
ATGATTCAGGTGATTGTTACCGATATTGAAGGCACCACCACTGACATCCGTTTTGTCCATCAAGTGCTGTTTCCTTATGC
CCGTGAGCGGTTGACACCTTTCTTACGTGCGCATCAGCAGGACGACGATATCGCTGCTCTACTGGTCGATTTACGCCGCG
AAATTGCTCAACCGGATGCCGATATTGAAACATTGATTACCGTTTTGCATGGTTTTATGGACGAAGACCGCAAATCTACC
GTATTGAAGGCCATTCAAGGCATTATCTGGCGCACGGGTTACTTGCAAGCGGATTTTCGTGGCCACGTGTATCCGGAAGT
TGCCCAACAACTGGCGGATTGGCACCAACAGGGGCTGAAGTTGTATGTCTATTCTTCTGGTTCAGTTGCGGCACAGAAGT
TGTTATTTGGCTACAGCGATGCTGGGGATTTATGCCCGCTGTTCAGTGGCTACTTTGATACCCATGTGGGGGCAAAACGA
GACGTGAGCGCTTATCAGAAGATTGCCAACCAACTGGGTATTGCGCCGCAGGCACTGCTATTTTTATCCGATATTCGCCA
AGAACTGGATGCCGCACAGCTGGCTGGCTGGCATACCTGCCAGTTGATTCGTGATCTACCCGATAATGACAGCGCTCATC
CACAAGTTAATCGTTTTGATCAGATTGTTTTAAGTCTGTTTACTGAATGA

Upstream 100 bases:

>100_bases
AGTTTTTGTTCCAGTGCGAGCTACAACGCCGTTTATTTGATGTGAATTCTAACGTTGATGTAAAACCTAACGTTGACGTA
AATCCTAACGTGGAGGCCAA

Downstream 100 bases:

>100_bases
TTGTTTTAAGTCTGTTTACTGAATGATTATTTTAAGTCTGTTTACCGAATGATTATCTTAAGTTCGTTTACAGAATAATT
GTTCCAGGTCAGTTTACCGC

Product: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MIQVIVTDIEGTTTDIRFVHQVLFPYARERLTPFLRAHQQDDDIAALLVDLRREIAQPDADIETLITVLHGFMDEDRKST
VLKAIQGIIWRTGYLQADFRGHVYPEVAQQLADWHQQGLKLYVYSSGSVAAQKLLFGYSDAGDLCPLFSGYFDTHVGAKR
DVSAYQKIANQLGIAPQALLFLSDIRQELDAAQLAGWHTCQLIRDLPDNDSAHPQVNRFDQIVLSLFTE

Sequences:

>Translated_229_residues
MIQVIVTDIEGTTTDIRFVHQVLFPYARERLTPFLRAHQQDDDIAALLVDLRREIAQPDADIETLITVLHGFMDEDRKST
VLKAIQGIIWRTGYLQADFRGHVYPEVAQQLADWHQQGLKLYVYSSGSVAAQKLLFGYSDAGDLCPLFSGYFDTHVGAKR
DVSAYQKIANQLGIAPQALLFLSDIRQELDAAQLAGWHTCQLIRDLPDNDSAHPQVNRFDQIVLSLFTE
>Mature_229_residues
MIQVIVTDIEGTTTDIRFVHQVLFPYARERLTPFLRAHQQDDDIAALLVDLRREIAQPDADIETLITVLHGFMDEDRKST
VLKAIQGIIWRTGYLQADFRGHVYPEVAQQLADWHQQGLKLYVYSSGSVAAQKLLFGYSDAGDLCPLFSGYFDTHVGAKR
DVSAYQKIANQLGIAPQALLFLSDIRQELDAAQLAGWHTCQLIRDLPDNDSAHPQVNRFDQIVLSLFTE

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family

Homologues:

Organism=Homo sapiens, GI10864017, Length=229, Percent_Identity=34.9344978165939, Blast_Score=150, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI115533232, Length=219, Percent_Identity=37.8995433789954, Blast_Score=143, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6320797, Length=201, Percent_Identity=32.8358208955224, Blast_Score=99, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281360080, Length=218, Percent_Identity=43.5779816513761, Blast_Score=177, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24644163, Length=218, Percent_Identity=43.5779816513761, Blast_Score=177, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNC_YERP3 (A7FLL3)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402141.1
- ProteinModelPortal:   A7FLL3
- SMR:   A7FLL3
- STRING:   A7FLL3
- GeneID:   5385893
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3181
- NMPDR:   fig|349747.3.peg.3524
- eggNOG:   COG4229
- HOGENOM:   HBG294242
- OMA:   TTDLNFI
- ProtClustDB:   CLSK866737
- BioCyc:   YPSE349747:YPSIP31758_3181-MONOMER
- HAMAP:   MF_01681
- InterPro:   IPR005834
- InterPro:   IPR010041
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR005833
- Gene3D:   G3DSA:3.40.50.1000
- PANTHER:   PTHR20371
- PRINTS:   PR00413
- TIGRFAMs:   TIGR01691
- TIGRFAMs:   TIGR01549

Pfam domain/function: PF00702 Hydrolase; SSF56784 SSF56784

EC number: =3.1.3.77

Molecular weight: Translated: 25856; Mature: 25856

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQVIVTDIEGTTTDIRFVHQVLFPYARERLTPFLRAHQQDDDIAALLVDLRREIAQPDA
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
DIETLITVLHGFMDEDRKSTVLKAIQGIIWRTGYLQADFRGHVYPEVAQQLADWHQQGLK
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCE
LYVYSSGSVAAQKLLFGYSDAGDLCPLFSGYFDTHVGAKRDVSAYQKIANQLGIAPQALL
EEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHH
FLSDIRQELDAAQLAGWHTCQLIRDLPDNDSAHPQVNRFDQIVLSLFTE
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIQVIVTDIEGTTTDIRFVHQVLFPYARERLTPFLRAHQQDDDIAALLVDLRREIAQPDA
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
DIETLITVLHGFMDEDRKSTVLKAIQGIIWRTGYLQADFRGHVYPEVAQQLADWHQQGLK
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCE
LYVYSSGSVAAQKLLFGYSDAGDLCPLFSGYFDTHVGAKRDVSAYQKIANQLGIAPQALL
EEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHH
FLSDIRQELDAAQLAGWHTCQLIRDLPDNDSAHPQVNRFDQIVLSLFTE
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA