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The map label for this gene is trpG

Identifier: 153948928

GI number: 153948928

Start: 2237617

End: 2238195

Strand: Direct

Name: trpG

Synonym: YpsIP31758_1933

Alternate gene names: 153948928

Gene position: 2237617-2238195 (Clockwise)

Preceding gene: 153947463

Following gene: 153948782

Centisome position: 47.37

GC content: 51.81

Gene sequence:

>579_bases
ATGGCCGATATCCTACTGCTCGATAATATCGACTCCTTTACCTACAACCTGGTGGACCAACTTCGTTCCAGTGGTCATCG
CGTCGTGATTTACCGTAACCACATTGCCGCCGATAACATTATTGAACGCTTGCAACAACTCGAACAACCGGTACTGATGT
TGTCACCTGGCCCTGGAACACCAGCACAGGCAGGCTGTATGCCTGAGCTATTGCAACGCTTACAGGGCCAGTTACCGATG
ATTGGTATTTGTCTGGGTCATCAAGCCATTATCGAAGCCTATGGCGGCCATGTTGGTCAAGCGGGTGAGATATTGCATGG
TAAGGCCTCGGCGATTGAACATGATGGGCAAGGTATGTTTGCCGGTATGCCAAACCCATTACCGGTCGCCCGCTACCACT
CCTTAGTCGGCAGTAATCTCCCCGCAGAATTAACCGTTAACGCCCGTTTTGGCGAGATGGTCATGGCGGTTCGTCATGAT
GCTCACCGCGTTTGTGGCTACCAATTCCACCCGGAATCGATTTTAACCACCCACGGTGCGCGTTTACTTGAACAAACACT
GGCCTGGGCGTTAGCGTAA

Upstream 100 bases:

>100_bases
TGGACTCAGTTCCACAAGCAGAAGCTGATGAAACTCGGAATAAAGCCAGAGCCGTACTGCGCGCCATTGCCACTGCCCAT
CATGCCAAGGAGATTTTCTA

Downstream 100 bases:

>100_bases
TTAAGGAGTTTATGATGCAACATTTATTCGAAAAACTGTTCCGGGCTGAGTCAATGAGCCAAGAAGAAAGCCAACAACTG
TTTGCGGCGATTGTACGTGG

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MADILLLDNIDSFTYNLVDQLRSSGHRVVIYRNHIAADNIIERLQQLEQPVLMLSPGPGTPAQAGCMPELLQRLQGQLPM
IGICLGHQAIIEAYGGHVGQAGEILHGKASAIEHDGQGMFAGMPNPLPVARYHSLVGSNLPAELTVNARFGEMVMAVRHD
AHRVCGYQFHPESILTTHGARLLEQTLAWALA

Sequences:

>Translated_192_residues
MADILLLDNIDSFTYNLVDQLRSSGHRVVIYRNHIAADNIIERLQQLEQPVLMLSPGPGTPAQAGCMPELLQRLQGQLPM
IGICLGHQAIIEAYGGHVGQAGEILHGKASAIEHDGQGMFAGMPNPLPVARYHSLVGSNLPAELTVNARFGEMVMAVRHD
AHRVCGYQFHPESILTTHGARLLEQTLAWALA
>Mature_191_residues
ADILLLDNIDSFTYNLVDQLRSSGHRVVIYRNHIAADNIIERLQQLEQPVLMLSPGPGTPAQAGCMPELLQRLQGQLPMI
GICLGHQAIIEAYGGHVGQAGEILHGKASAIEHDGQGMFAGMPNPLPVARYHSLVGSNLPAELTVNARFGEMVMAVRHDA
HRVCGYQFHPESILTTHGARLLEQTLAWALA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI1787517, Length=190, Percent_Identity=82.1052631578947, Blast_Score=332, Evalue=1e-92,
Organism=Escherichia coli, GI1789760, Length=188, Percent_Identity=43.0851063829787, Blast_Score=149, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322638, Length=188, Percent_Identity=40.9574468085106, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324361, Length=209, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPG_YERPE (Q8ZEG6)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AI0268
- RefSeq:   NP_993344.1
- RefSeq:   YP_002347178.1
- ProteinModelPortal:   Q8ZEG6
- SMR:   Q8ZEG6
- GeneID:   1175040
- GeneID:   2766189
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO2207
- KEGG:   ypm:YP_2005
- HOGENOM:   HBG292341
- OMA:   YGGKVER
- ProtClustDB:   PRK05670
- BioCyc:   YPES214092:YPO2207-MONOMER
- BRENDA:   4.1.3.27
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221
- PRINTS:   PR00097
- PRINTS:   PR00099
- PRINTS:   PR00096
- TIGRFAMs:   TIGR00566

Pfam domain/function: PF00117 GATase

EC number: =4.1.3.27

Molecular weight: Translated: 20882; Mature: 20751

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS51273 GATASE_TYPE_1; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 84-84 ACT_SITE 170-170 ACT_SITE 172-172

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADILLLDNIDSFTYNLVDQLRSSGHRVVIYRNHIAADNIIERLQQLEQPVLMLSPGPGT
CCCEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCC
PAQAGCMPELLQRLQGQLPMIGICLGHQAIIEAYGGHVGQAGEILHGKASAIEHDGQGMF
CCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHEEECCCEEE
AGMPNPLPVARYHSLVGSNLPAELTVNARFGEMVMAVRHDAHRVCGYQFHPESILTTHGA
CCCCCCCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHH
RLLEQTLAWALA
HHHHHHHHHHCC
>Mature Secondary Structure 
ADILLLDNIDSFTYNLVDQLRSSGHRVVIYRNHIAADNIIERLQQLEQPVLMLSPGPGT
CCEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCC
PAQAGCMPELLQRLQGQLPMIGICLGHQAIIEAYGGHVGQAGEILHGKASAIEHDGQGMF
CCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHEEECCCEEE
AGMPNPLPVARYHSLVGSNLPAELTVNARFGEMVMAVRHDAHRVCGYQFHPESILTTHGA
CCCCCCCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHH
RLLEQTLAWALA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430