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The map label for this gene is pepT2

Identifier: 153948676

GI number: 153948676

Start: 1863491

End: 1864726

Strand: Direct

Name: pepT2

Synonym: YpsIP31758_1605

Alternate gene names: 153948676

Gene position: 1863491-1864726 (Clockwise)

Preceding gene: 153947974

Following gene: 153950862

Centisome position: 39.45

GC content: 45.23

Gene sequence:

>1236_bases
ATGGACAAATTACTCGACCGATTTTTCAACTATGTTTCTTTTGATACACAAGCAAAAGCCAATGTAAAATCTGTGCCGAG
CACTCAGGGACAGCGCAAGCTTGCTCAGGCGTTGCAACAGGAATTATTGACGTTGGGCTTTTCCCACGTCACCTTGAGCG
ATCATGGTTGCGTGATGGCAACATTGCCAGCAAATGTCTCCTGGCCGGTCCCCACGATTGGCTTTATTGCCCATCTGGAC
ACCTCACCAGATTTTTCAGGTAAAAATGTTAATCCACAGATAGTGGAGAACTACCGTGGTGGTGATATTGCGTTAGGTAT
TGGTGATGAGGTTTTATCTCCTGTTATGTTCCCGGTATTACATCAATTACTTGGACATACCTTGATCACGACTGATGGTA
AAACCCTGTTAGGGGCGGATGATAAAGCGGGTATTGCTGAAATCATTACCGCTATGGTGCGCTTAAAGCACCGTAATGTC
CCCCATGGGGATATTCGTATTGCCTTCACACCGGATGAAGAAGTGGGTAAGGGGGCTCAGTTTTTTAATGTGGCAGAGTT
TGATGCACAGTGGGCTTATACCGTTGATGGTGGCGGCATTGGTGAATTAGAGTTTGAAAATTTCAATGCAGCATCGGTGG
CAATAAAGATCGTCGGCAATAATGTTCATCCAGGCAGTGCTAAGGGCGTCATGGTTAATGCGTTGTCGCTGGCAACCCGT
TACCATCAAGAGTTGCCAGTAGATGAAACCCCAGAGTGTACTGAGGGTTACGACGGTTTCTATCATCTGCAAAGTATTAA
AGGCACGGTTGAACGCGCTGAGATGCACTACATTGTTCGAGATTTCAATCGCGATAGCTTTGAAGCGCGGAAGAAGAATA
TGGTGGATATCGCCAAGCGGGTTGGTAAAGGTTTACATCGTGATTGTTATATCGAAATTGTTATCGATGACAGCTATTAC
AATATGCGTGAGCAGATTATTAAGCACCCGCACATTATCGAATTAGCCCAACAGGCCATGCTTGACTGTGATATTACTCC
GATTATGAAGCCAATTCGTGGTGGTACCGATGGTGCACAACTCTCTTTTAAAGGGTTACCTTGCCCGAATATTTTTACCG
GAGGCTATAATTACCACGGTAAACATGAGTTTATTACGCTGGAAGGGATGGAAAAAGCGGTTGCAGTCATTATGCGAATT
TCTGAGCTGACCGCCAAGCGGGCTAAAGAGTTATAA

Upstream 100 bases:

>100_bases
CTTATTATTCTGGCTTAAGTTTATCTAAAGCTGACCTGACGCAATATTTGATCATGATCACTTCCCCATAATGTTATTCA
CTATTATGAGGGTGGGAACC

Downstream 100 bases:

>100_bases
GCTGAACGATAGAGAGAAACGCCTCGAAAAGGGGCGTTTGAGTTTATTGACAAAGTGCCCGTAGCGGAGTGAATAGGCAG
CAAGTAAAGACGCTGTAAAC

Product: peptidase T

Products: NA

Alternate protein names: Aminotripeptidase; Tripeptidase; Tripeptide aminopeptidase

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMATLPANVSWPVPTIGFIAHLD
TSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIITAMVRLKHRNV
PHGDIRIAFTPDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGVMVNALSLATR
YHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKRVGKGLHRDCYIEIVIDDSYY
NMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGMEKAVAVIMRI
SELTAKRAKEL

Sequences:

>Translated_411_residues
MDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMATLPANVSWPVPTIGFIAHLD
TSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIITAMVRLKHRNV
PHGDIRIAFTPDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGVMVNALSLATR
YHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKRVGKGLHRDCYIEIVIDDSYY
NMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGMEKAVAVIMRI
SELTAKRAKEL
>Mature_411_residues
MDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMATLPANVSWPVPTIGFIAHLD
TSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGHTLITTDGKTLLGADDKAGIAEIITAMVRLKHRNV
PHGDIRIAFTPDEEVGKGAQFFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGVMVNALSLATR
YHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKRVGKGLHRDCYIEIVIDDSYY
NMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQLSFKGLPCPNIFTGGYNYHGKHEFITLEGMEKAVAVIMRI
SELTAKRAKEL

Specific function: Cleaves the N-terminal amino acid of tripeptides

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20B family

Homologues:

Organism=Escherichia coli, GI1787372, Length=407, Percent_Identity=76.9041769041769, Blast_Score=675, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PEPT_YERP3 (A7FH54)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400582.1
- ProteinModelPortal:   A7FH54
- SMR:   A7FH54
- STRING:   A7FH54
- GeneID:   5384393
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1605
- NMPDR:   fig|349747.3.peg.930
- eggNOG:   COG2195
- HOGENOM:   HBG288638
- OMA:   HMDTAPD
- ProtClustDB:   PRK05469
- BioCyc:   YPSE349747:YPSIP31758_1605-MONOMER
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_00550
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010161
- PIRSF:   PIRSF037215
- TIGRFAMs:   TIGR01882

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: =3.4.11.4

Molecular weight: Translated: 45413; Mature: 45413

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2

Important sites: ACT_SITE 80-80 ACT_SITE 173-173

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMA
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEE
TLPANVSWPVPTIGFIAHLDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVL
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHH
HQLLGHTLITTDGKTLLGADDKAGIAEIITAMVRLKHRNVPHGDIRIAFTPDEEVGKGAQ
HHHHCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCCCCC
FFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGVMVNALSLATR
EEEEEECCCEEEEEECCCCCCCEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
YHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKR
HHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VGKGLHRDCYIEIVIDDSYYNMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQ
HCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCE
LSFKGLPCPNIFTGGYNYHGKHEFITLEGMEKAVAVIMRISELTAKRAKEL
EEECCCCCCCCEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKLLDRFFNYVSFDTQAKANVKSVPSTQGQRKLAQALQQELLTLGFSHVTLSDHGCVMA
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEE
TLPANVSWPVPTIGFIAHLDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVL
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHH
HQLLGHTLITTDGKTLLGADDKAGIAEIITAMVRLKHRNVPHGDIRIAFTPDEEVGKGAQ
HHHHCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCCCCC
FFNVAEFDAQWAYTVDGGGIGELEFENFNAASVAIKIVGNNVHPGSAKGVMVNALSLATR
EEEEEECCCEEEEEECCCCCCCEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
YHQELPVDETPECTEGYDGFYHLQSIKGTVERAEMHYIVRDFNRDSFEARKKNMVDIAKR
HHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VGKGLHRDCYIEIVIDDSYYNMREQIIKHPHIIELAQQAMLDCDITPIMKPIRGGTDGAQ
HCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCE
LSFKGLPCPNIFTGGYNYHGKHEFITLEGMEKAVAVIMRISELTAKRAKEL
EEECCCCCCCCEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA