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The map label for this gene is codA [H]

Identifier: 153948211

GI number: 153948211

Start: 4435470

End: 4436780

Strand: Reverse

Name: codA [H]

Synonym: YpsIP31758_3955

Alternate gene names: 153948211

Gene position: 4436780-4435470 (Counterclockwise)

Preceding gene: 153947109

Following gene: 153949326

Centisome position: 93.93

GC content: 51.72

Gene sequence:

>1311_bases
GTGGAGGCATTGATGGCAGGGCAATCTGTACCGAATTATTCATTAACGACGGTAAATAATGTGCGTCGTATAGGGTTAGC
GGGGCTGTGGCAGATAACGATAGCGGAAGGCAAAATCAGCCTGATTCAGCCTCAGCCGGAGCAATCCCTAACAGGGCAAG
GTGTGCTGGATGCGCAGGGCGGTTTGGCGCTCCCGCCATTTATTGAGCCGCATATTCATCTGGATACGACTCAAACCGCT
GGGCAACCGAGTTGGAATCAGTCGGGAACTCTGTTTGAGGGAATTGAACGTTGGGCGGAGCGCAAAGCGCGACTAACGCG
CGAGGATGTGAAGCAGCGGGCCTGGCAAACATTGAAATGGCAGATAGCCAACGGTATCCAGCATGTCCGAACGCATGTTG
ATGTTTCCGATCCACACTTGACGGCATTGAGCGCCATGTTGGAGGTGAAAGAAGAGGTTAGCCCTTGGGTTGATATGCAG
ATTGTGGCTTTCCCACAAGAGGGCATCCTCTCTTATCCTGATGGTGCGGCGTTATTGGAAGAGGCACTGCGCTTGGGTGC
GGATGCGGTGGGGGCGATCCCCCATTTTGAATTTACCCGCGAATATGGCGTGGAATCTTTGCATATCGCGTTTGCATTGG
CGCAAAAATATCAGCGGCTGGTGGATGTTCATTGCGATGAAACGGATGATGAGCAATCGCGCTTTATCGAAACCGTGGCG
GCGCTGGCCCTTCGCGAAAATATGGGCGCACGGGTAACCGCCAGCCATACCACGGCGATGCACTCTTATAATGGTGCCTA
TACATCACGGCTGTTCCGCTTGCTGAAATTATCGGGCATTAATTTTGTCGCCAACCCGCTGGTGAATATTCATCTGCAAG
GCCGTTTTGATACTTATCCGAAGCGGCGTGGTATCACGCGGGTCAAAGAGATGTTGGCTGCCGAGATTAATGTGTGCTTC
GGCCATGACGATGTGTTCGACCCGTGGTATCCGCTAGGTACCGCCAATATGTTGCAGGTGCTGCATATGGGATTACATAT
TTGTCAGTTGATGGGATATGAACAAATTAATGATGGTCTGAATCTGATAACCACCCACAGTGCCAAGACGCTGAATTTAG
CAGATTATGGTTTGCAGCCTGGTAACCGCGCCAACCTGATTATTCTACCCGCAGAAAATGGTTTTGATGCTCTACGGCGG
CAGGTTCCCGTCAGTTACTCTATTCGTCATGGTGTGGTGATCGCGAAGACGCAACCCGCAGAGAGCCGGATATATCTGGG
GCAGGAAGAGATCGTGGATTTTCGGCGTTAA

Upstream 100 bases:

>100_bases
GAGAAAATGATTATGAGTAAAAGAAAATCGGGCAGGCGAGGGTGGCTCAGGTAAGCTAAAGAAAACCGCTTTTCGTGATG
ACGAGAGGAGGAAAGAGAGA

Downstream 100 bases:

>100_bases
CGGTAGGATTTTCGATGTTTACGGCATTAGTGAATCATCAATACCCTGCCACCTTGGCGGCGGCAGGGCAGTAACGCAGA
TAAATCAGTGGGTCACGTGG

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MEALMAGQSVPNYSLTTVNNVRRIGLAGLWQITIAEGKISLIQPQPEQSLTGQGVLDAQGGLALPPFIEPHIHLDTTQTA
GQPSWNQSGTLFEGIERWAERKARLTREDVKQRAWQTLKWQIANGIQHVRTHVDVSDPHLTALSAMLEVKEEVSPWVDMQ
IVAFPQEGILSYPDGAALLEEALRLGADAVGAIPHFEFTREYGVESLHIAFALAQKYQRLVDVHCDETDDEQSRFIETVA
ALALRENMGARVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLAAEINVCF
GHDDVFDPWYPLGTANMLQVLHMGLHICQLMGYEQINDGLNLITTHSAKTLNLADYGLQPGNRANLIILPAENGFDALRR
QVPVSYSIRHGVVIAKTQPAESRIYLGQEEIVDFRR

Sequences:

>Translated_436_residues
MEALMAGQSVPNYSLTTVNNVRRIGLAGLWQITIAEGKISLIQPQPEQSLTGQGVLDAQGGLALPPFIEPHIHLDTTQTA
GQPSWNQSGTLFEGIERWAERKARLTREDVKQRAWQTLKWQIANGIQHVRTHVDVSDPHLTALSAMLEVKEEVSPWVDMQ
IVAFPQEGILSYPDGAALLEEALRLGADAVGAIPHFEFTREYGVESLHIAFALAQKYQRLVDVHCDETDDEQSRFIETVA
ALALRENMGARVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLAAEINVCF
GHDDVFDPWYPLGTANMLQVLHMGLHICQLMGYEQINDGLNLITTHSAKTLNLADYGLQPGNRANLIILPAENGFDALRR
QVPVSYSIRHGVVIAKTQPAESRIYLGQEEIVDFRR
>Mature_436_residues
MEALMAGQSVPNYSLTTVNNVRRIGLAGLWQITIAEGKISLIQPQPEQSLTGQGVLDAQGGLALPPFIEPHIHLDTTQTA
GQPSWNQSGTLFEGIERWAERKARLTREDVKQRAWQTLKWQIANGIQHVRTHVDVSDPHLTALSAMLEVKEEVSPWVDMQ
IVAFPQEGILSYPDGAALLEEALRLGADAVGAIPHFEFTREYGVESLHIAFALAQKYQRLVDVHCDETDDEQSRFIETVA
ALALRENMGARVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLAAEINVCF
GHDDVFDPWYPLGTANMLQVLHMGLHICQLMGYEQINDGLNLITTHSAKTLNLADYGLQPGNRANLIILPAENGFDALRR
QVPVSYSIRHGVVIAKTQPAESRIYLGQEEIVDFRR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=427, Percent_Identity=80.0936768149883, Blast_Score=717, Evalue=0.0,
Organism=Escherichia coli, GI1786517, Length=321, Percent_Identity=25.5451713395639, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 48628; Mature: 48628

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALMAGQSVPNYSLTTVNNVRRIGLAGLWQITIAEGKISLIQPQPEQSLTGQGVLDAQG
CCCCCCCCCCCCCEEEEHHHHHHHCCCEEEEEEEECCEEEEECCCCCCCCCCCCEEECCC
GLALPPFIEPHIHLDTTQTAGQPSWNQSGTLFEGIERWAERKARLTREDVKQRAWQTLKW
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QIANGIQHVRTHVDVSDPHLTALSAMLEVKEEVSPWVDMQIVAFPQEGILSYPDGAALLE
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHH
EALRLGADAVGAIPHFEFTREYGVESLHIAFALAQKYQRLVDVHCDETDDEQSRFIETVA
HHHHHCCHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALALRENMGARVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDTYP
HHHHHHCCCCEEEECCHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCC
KRRGITRVKEMLAAEINVCFGHDDVFDPWYPLGTANMLQVLHMGLHICQLMGYEQINDGL
HHCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCC
NLITTHSAKTLNLADYGLQPGNRANLIILPAENGFDALRRQVPVSYSIRHGVVIAKTQPA
CEEEECCCCEEEHHHCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEECCCEEEEECCCC
ESRIYLGQEEIVDFRR
CCEEEECHHHHHHCCC
>Mature Secondary Structure
MEALMAGQSVPNYSLTTVNNVRRIGLAGLWQITIAEGKISLIQPQPEQSLTGQGVLDAQG
CCCCCCCCCCCCCEEEEHHHHHHHCCCEEEEEEEECCEEEEECCCCCCCCCCCCEEECCC
GLALPPFIEPHIHLDTTQTAGQPSWNQSGTLFEGIERWAERKARLTREDVKQRAWQTLKW
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QIANGIQHVRTHVDVSDPHLTALSAMLEVKEEVSPWVDMQIVAFPQEGILSYPDGAALLE
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHH
EALRLGADAVGAIPHFEFTREYGVESLHIAFALAQKYQRLVDVHCDETDDEQSRFIETVA
HHHHHCCHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALALRENMGARVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDTYP
HHHHHHCCCCEEEECCHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCC
KRRGITRVKEMLAAEINVCFGHDDVFDPWYPLGTANMLQVLHMGLHICQLMGYEQINDGL
HHCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCC
NLITTHSAKTLNLADYGLQPGNRANLIILPAENGFDALRRQVPVSYSIRHGVVIAKTQPA
CEEEECCCCEEEHHHCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEECCCEEEEECCCC
ESRIYLGQEEIVDFRR
CCEEEECHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]