Click here to switch to the map view.

The map label for this gene is ubiA [H]

Identifier: 153947917

GI number: 153947917

Start: 4252565

End: 4253431

Strand: Reverse

Name: ubiA [H]

Synonym: YpsIP31758_3773

Alternate gene names: 153947917

Gene position: 4253431-4252565 (Counterclockwise)

Preceding gene: 153947599

Following gene: 153947443

Centisome position: 90.05

GC content: 48.33

Gene sequence:

>867_bases
TTGAAGGGAAGTACTGTTCATACCAAATGGCAGGCTTATTGCCGTTTGATGCGTATTGACAAACCGATTGGCTCACTGCT
GCTGCTGTGGCCAACATTGTGGGCATTGTGGTTAGCAGGGAGAGGCATCCCCGAGGCCAAAATACTGGTCGTTTTTGTAC
TGGGGGTCTTTTTCATGCGTGCGGCAGGGTGTGTCGTCAATGATTATGCTGACCGCCATATTGATGGTTTTGTCAAACGC
ACCGCATCCCGGCCACTGCCTAGCGGCACTATCAGTGAGAAAGAGAGCAAAATTCTATTTGTGGTATTGATATTGCTCTC
TTTTGGTTTGGTATTGACCCTCAATAGCATGACGATATGGCTGTCACTGGCCGCATTGGCACTGGCTTGGATCTATCCAT
TTATGAAGCGGGTGACTCATCTGCCGCAGGTGGTATTAGGCGCAGCATTTGGTTGGTCTATTCCGATGGGGTTTGCCGCC
GTTAGCGAAAGCTTGCCGCTGGTCTGCTGGCTACTGTTGCTGGCAAATATCTGCTGGACCGTGGCCTATGACACTCAATA
CGCCATGGTTGATCGTGACGATGACCTAAGAATTGGGGTTAAATCTACGGCGATTCTGTTTGGTCAACATGACAAATTGA
TTATCGGCTTGCTGCAACTGGCGACGTTATTATTAATGGTGGCCATTGGCTGGCTAATGAATCTGGGCGGTGCATTTTAT
TGGTCAATCCTTCTCGCCGGTGCTCTGTTTACTCATCAACAGAAAATGATCGCCCAGCGTGAGCGTGAGCCGTGTTTTCG
TGCGTTTTTGAACAATAATTACGTGGGGTTGATTTTGTTTCTCGGGATATTGATCAGTTACTGGTAA

Upstream 100 bases:

>100_bases
GTAGGCGAATACCGTTGACCTCCCTGCCACATTCAAGATGAAAAGGGTATATCAGGTTTAAGCTAGCTGATTCCGTCGTT
AGATTCTGGAGACTGATCAA

Downstream 100 bases:

>100_bases
CCCGCTTTTACTGGGGGTTAGCGATGACTGAGTATGAGCGCAGAGTCCTCTCACCAAGATACCGAGTTCTCACCAAGGTA
ATGGTAAAAAATGGCCGGAT

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMRAAGCVVNDYADRHIDGFVKR
TASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIWLSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAA
VSESLPLVCWLLLLANICWTVAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFY
WSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLILFLGILISYW

Sequences:

>Translated_288_residues
MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMRAAGCVVNDYADRHIDGFVKR
TASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIWLSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAA
VSESLPLVCWLLLLANICWTVAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFY
WSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLILFLGILISYW
>Mature_288_residues
MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMRAAGCVVNDYADRHIDGFVKR
TASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIWLSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAA
VSESLPLVCWLLLLANICWTVAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFY
WSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLILFLGILISYW

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=279, Percent_Identity=37.9928315412186, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1790473, Length=288, Percent_Identity=73.2638888888889, Blast_Score=416, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17553718, Length=282, Percent_Identity=35.8156028368794, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI32565247, Length=279, Percent_Identity=35.4838709677419, Blast_Score=153, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17553720, Length=248, Percent_Identity=34.2741935483871, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI32565245, Length=139, Percent_Identity=41.0071942446043, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32565243, Length=138, Percent_Identity=40.5797101449275, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324370, Length=293, Percent_Identity=31.740614334471, Blast_Score=143, Evalue=4e-35,
Organism=Drosophila melanogaster, GI21355567, Length=278, Percent_Identity=39.9280575539568, Blast_Score=199, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32294; Mature: 32294

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMR
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AAGCVVNDYADRHIDGFVKRTASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIW
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAAVSESLPLVCWLLLLANICWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHH
VAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFY
HHCCCEEEEECCCCCCEEEEHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLILFLGILISYW
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMR
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AAGCVVNDYADRHIDGFVKRTASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIW
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAAVSESLPLVCWLLLLANICWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHH
VAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFY
HHCCCEEEEECCCCCCEEEEHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLILFLGILISYW
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA