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The map label for this gene is argD [H]

Identifier: 153947780

GI number: 153947780

Start: 4423871

End: 4425088

Strand: Reverse

Name: argD [H]

Synonym: YpsIP31758_3947

Alternate gene names: 153947780

Gene position: 4425088-4423871 (Counterclockwise)

Preceding gene: 153947271

Following gene: 153949647

Centisome position: 93.69

GC content: 52.96

Gene sequence:

>1218_bases
ATGACAGATAAGTTAGCAGTGAATCGCAAGACATTCGATCAGGTCATTTTGCCTGTTTATGCACCCGCGCAGTTTATCCC
AGTAAAAGGGAAAGGCAGCCGAGTGTGGGATCAACAAGGTACGGAGTACATTGATTTCGCCGGTGGCATTGCGGTTACCG
CACTGGGCCATTGCCATCCGGCACTGGTATCCGCATTGCATCAGCAGGGTGAAACGTTGTGGCACACCAGTAATGTGTTT
ACCAATGAGCCAGCACTGCGTTTAGCACAGAAGCTGATTGCCGCAACCTTTGCTGACCGGGTTTTCTTTGCCAACTCGGG
TGCTGAAGCGAATGAAGCCGCATTTAAGTTAGCTCGCCATTACGCTATTGAGCGTCATAGCCCCTATAAAACCAAGATTA
TTGCTTTCCACAATGCGTTTCATGGCCGCACCCTGTTTACGGTCTCTGTCGGGGGGCAGCCAAAGTATTCCGATGGTTTT
GGCCCGAAACCTGCGGATATCATCCATGTCCCGTTTAATGATCTGGCGGCAGTGAAAGCGGTGATGGATGATCACACCTG
TGCCGTGGTACTGGAACCGATTCAGGGAGAGGGCGGGATCACTTCTGCCACGCCAGAGTTCCTACAAGGGGTGCGCGCGT
TGTGTGATCAACATAACGCCCTGCTGGTGTTTGATGAAGTGCAAAGCGGTATGGGGCGCAGTGGCAAGTTGTTTAGCTAT
ATGCATTATGGTGTGACGCCGGATATCCTTACCACAGCGAAGGCATTGGGCGGTGGCTTCCCAATCAGTGCGATGCTAAC
GACCGAAGAGATCGCTTCAGTGATGACGGTGGGTGCCCACGGCACCACCTATGGGGGTAATCCTCTGGCCTGTGCGGTCG
CTGAGGCCGCGTTGGATGTGATTAATACCCCTGAGGTACTTAATGGTATTGAACAGCGCCATGGTCTGTTTGTGCAGGCG
CTACAAAGCATCAACAGCAAGTATGATGTTTTCAGTGATATTCGTGGTATGGGGTTGTTGATTGGCGCGGAGTTAACCGC
GAAATACCGGGGGCAGGCGCGTGAGTTCCTGGCCGCCGCTGCCGCTAACGGCTTGATGATCCTCAATGCGGGTCCAGATG
TTCTGCGGTTAGCGCCCTCGCTGGTGATTGAATTGGAGGATATCCAGCAAGGGATGGGGCGGTTGGAGAAAGCAATGGCG
AGTGTGATCAAAGGTTAA

Upstream 100 bases:

>100_bases
TTATCATTTGCTTGTGGATGATTTTTTATGCATATTTTGTGAGTATATTTTCACGCGTCAATAAATAACAGCTTAGTGGT
TTATTAGGGTGGGCAGGGTA

Downstream 100 bases:

>100_bases
GCAGTCAATAACCGCGTTATGGAGAGGCGCTAGCCTCTCTCTTTTTACGTATTATCCCGTAACTTCCGGCTGCGCCATAT
GCCATGATGTGGCTGCTGTT

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT; DapATase; Succinyldiaminopimelate transferase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTDKLAVNRKTFDQVILPVYAPAQFIPVKGKGSRVWDQQGTEYIDFAGGIAVTALGHCHPALVSALHQQGETLWHTSNVF
TNEPALRLAQKLIAATFADRVFFANSGAEANEAAFKLARHYAIERHSPYKTKIIAFHNAFHGRTLFTVSVGGQPKYSDGF
GPKPADIIHVPFNDLAAVKAVMDDHTCAVVLEPIQGEGGITSATPEFLQGVRALCDQHNALLVFDEVQSGMGRSGKLFSY
MHYGVTPDILTTAKALGGGFPISAMLTTEEIASVMTVGAHGTTYGGNPLACAVAEAALDVINTPEVLNGIEQRHGLFVQA
LQSINSKYDVFSDIRGMGLLIGAELTAKYRGQAREFLAAAAANGLMILNAGPDVLRLAPSLVIELEDIQQGMGRLEKAMA
SVIKG

Sequences:

>Translated_405_residues
MTDKLAVNRKTFDQVILPVYAPAQFIPVKGKGSRVWDQQGTEYIDFAGGIAVTALGHCHPALVSALHQQGETLWHTSNVF
TNEPALRLAQKLIAATFADRVFFANSGAEANEAAFKLARHYAIERHSPYKTKIIAFHNAFHGRTLFTVSVGGQPKYSDGF
GPKPADIIHVPFNDLAAVKAVMDDHTCAVVLEPIQGEGGITSATPEFLQGVRALCDQHNALLVFDEVQSGMGRSGKLFSY
MHYGVTPDILTTAKALGGGFPISAMLTTEEIASVMTVGAHGTTYGGNPLACAVAEAALDVINTPEVLNGIEQRHGLFVQA
LQSINSKYDVFSDIRGMGLLIGAELTAKYRGQAREFLAAAAANGLMILNAGPDVLRLAPSLVIELEDIQQGMGRLEKAMA
SVIKG
>Mature_404_residues
TDKLAVNRKTFDQVILPVYAPAQFIPVKGKGSRVWDQQGTEYIDFAGGIAVTALGHCHPALVSALHQQGETLWHTSNVFT
NEPALRLAQKLIAATFADRVFFANSGAEANEAAFKLARHYAIERHSPYKTKIIAFHNAFHGRTLFTVSVGGQPKYSDGFG
PKPADIIHVPFNDLAAVKAVMDDHTCAVVLEPIQGEGGITSATPEFLQGVRALCDQHNALLVFDEVQSGMGRSGKLFSYM
HYGVTPDILTTAKALGGGFPISAMLTTEEIASVMTVGAHGTTYGGNPLACAVAEAALDVINTPEVLNGIEQRHGLFVQAL
QSINSKYDVFSDIRGMGLLIGAELTAKYRGQAREFLAAAAANGLMILNAGPDVLRLAPSLVIELEDIQQGMGRLEKAMAS
VIKG

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=35.9173126614987, Blast_Score=235, Evalue=5e-62,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=36.5448504983389, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI13994255, Length=412, Percent_Identity=28.3980582524272, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI37574042, Length=438, Percent_Identity=27.8538812785388, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=29.0155440414508, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI24119277, Length=412, Percent_Identity=26.6990291262136, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI226442705, Length=438, Percent_Identity=26.7123287671233, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1789759, Length=401, Percent_Identity=77.5561097256858, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI1788044, Length=392, Percent_Identity=63.0102040816327, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1789016, Length=395, Percent_Identity=36.4556962025316, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI145693181, Length=389, Percent_Identity=35.73264781491, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1787560, Length=404, Percent_Identity=33.4158415841584, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI1786991, Length=315, Percent_Identity=32.3809523809524, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786349, Length=302, Percent_Identity=31.4569536423841, Blast_Score=124, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=390, Percent_Identity=36.6666666666667, Blast_Score=248, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI25144274, Length=274, Percent_Identity=37.2262773722628, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI32564660, Length=424, Percent_Identity=30.4245283018868, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=28.2051282051282, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17541228, Length=438, Percent_Identity=24.6575342465753, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71981843, Length=165, Percent_Identity=32.7272727272727, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=39.6464646464646, Blast_Score=290, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=35.5721393034826, Blast_Score=223, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6324386, Length=314, Percent_Identity=30.5732484076433, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6321456, Length=429, Percent_Identity=24.7086247086247, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357415, Length=388, Percent_Identity=35.5670103092784, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI161085790, Length=415, Percent_Identity=28.9156626506024, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28574759, Length=404, Percent_Identity=29.2079207920792, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI21356575, Length=448, Percent_Identity=26.5625, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281366494, Length=438, Percent_Identity=22.8310502283105, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667139, Length=438, Percent_Identity=22.8310502283105, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667143, Length=438, Percent_Identity=22.8310502283105, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11; =2.6.1.17 [H]

Molecular weight: Translated: 43301; Mature: 43170

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKLAVNRKTFDQVILPVYAPAQFIPVKGKGSRVWDQQGTEYIDFAGGIAVTALGHCHP
CCCCCCCCHHHHHHHHHHEECCCEEEEECCCCCCCHHCCCCEEEECCCCHHHHHHHCCHH
ALVSALHQQGETLWHTSNVFTNEPALRLAQKLIAATFADRVFFANSGAEANEAAFKLARH
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
YAIERHSPYKTKIIAFHNAFHGRTLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLAAVKA
HHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHH
VMDDHTCAVVLEPIQGEGGITSATPEFLQGVRALCDQHNALLVFDEVQSGMGRSGKLFSY
HHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEEE
MHYGVTPDILTTAKALGGGFPISAMLTTEEIASVMTVGAHGTTYGGNPLACAVAEAALDV
HHCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHH
INTPEVLNGIEQRHGLFVQALQSINSKYDVFSDIRGMGLLIGAELTAKYRGQAREFLAAA
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHH
AANGLMILNAGPDVLRLAPSLVIELEDIQQGMGRLEKAMASVIKG
HCCCEEEEECCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDKLAVNRKTFDQVILPVYAPAQFIPVKGKGSRVWDQQGTEYIDFAGGIAVTALGHCHP
CCCCCCCHHHHHHHHHHEECCCEEEEECCCCCCCHHCCCCEEEECCCCHHHHHHHCCHH
ALVSALHQQGETLWHTSNVFTNEPALRLAQKLIAATFADRVFFANSGAEANEAAFKLARH
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
YAIERHSPYKTKIIAFHNAFHGRTLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLAAVKA
HHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHH
VMDDHTCAVVLEPIQGEGGITSATPEFLQGVRALCDQHNALLVFDEVQSGMGRSGKLFSY
HHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEEE
MHYGVTPDILTTAKALGGGFPISAMLTTEEIASVMTVGAHGTTYGGNPLACAVAEAALDV
HHCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHH
INTPEVLNGIEQRHGLFVQALQSINSKYDVFSDIRGMGLLIGAELTAKYRGQAREFLAAA
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHH
AANGLMILNAGPDVLRLAPSLVIELEDIQQGMGRLEKAMASVIKG
HCCCEEEEECCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]