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The map label for this gene is mtnK

Identifier: 153947416

GI number: 153947416

Start: 3582506

End: 3583729

Strand: Reverse

Name: mtnK

Synonym: YpsIP31758_3178

Alternate gene names: 153947416

Gene position: 3583729-3582506 (Counterclockwise)

Preceding gene: 153950848

Following gene: 153948143

Centisome position: 75.87

GC content: 50.08

Gene sequence:

>1224_bases
ATGTCGCGCTACCATACGTTTACTGCTGCGGATGCGGTTGAATATGCACGCCAATTTGGTCAGGTGGCCGATCCACAGGC
CTTGGTGACGGCTGATGAAATTGGGGATGGAAACCTCAATTTGGTGTTTAAAATTCGTGATACAGCAGGAATAAGCCGGG
TGATTGTTAAACAGGCTCTGCCTTATGTGCGTTGTGTGGGGGAGTCCTGGCCGTTAACGTTGGATCGCGCGCGCATTGAG
GCGGAAACATTGCTGACACACAGCCAATTCTGCCCGCAACATACGGTGAAGGTGCTGCACCATGATGCGGAATTGGCGGT
GATGGTGCAGGAAGATTTGTCTGATCACCATATTTGGCGTCACGAGTTGATTCAGGGAAATTATTACCCACAGGCAGCAG
AACAACTGGGTGAATATTTAGCGCAGACGTTATTCCATACCTCTGATTTCTACCAGTCTGCGCAAGCGAAAAAAGCGGCG
GTGAGCCGTTATACCAACCCGGAATTATGCCAAATCACCGAAGATCTGTTCTTTACCGACCCCTATATTGATCACGAACG
TAATAATTTTGATCCGGTACTTTTGCCAGAGGTGCTGTCGTTAAGACAAGATAAGGCGCTCAAGTTAGCCGTAGCCTCAC
TGAAACATCGTTTCCTGAGCCAGGCAGAGGCATTACTTCACGGCGATATTCACAGTGGTTCAATTTTTGTTGCTGATGGC
CGTTTGAAAACTATTGATGCTGAATTTGGTTTTTATGGCCCTATTGGTTTTGATATCGGTACCGCGCTTGGGAATTTACT
GCTTAATTACTGTGGGTTACCGGGATTAGCAGGTCCCCGTGATGCGGCGGCGGGGCGTGAACAACGACTGAAAGATGTCC
AAACGGTTTGGCAAACATTCGCCGCCCGTTTTTTGGCTTTAAGTCAGGAAAAAGCACAGGATCCCGCGTTGGCGACGGAA
GGTTATGCTGCGCAATTTTTACAGCACGTTTGGCGGGATGCTATTGGTTATTGCGGTAGTGAGTTAATTCGCCGCACCAT
TGGTTTAGCCCACGTTGCTGATTTGGATTCTATTGACGATGAAGAGATGCGCCGTGCATGCCAGCGCCACGCATTAAGTT
TGGGGCGCGCACTGATTTTGGTCGCGCCACATGTTGATGATGTGGGGGGGGTTGTTGCCCGCATCCGCCAATCCCCTTCG
TCCTTGACGCCGCAGCGGTGTTAG

Upstream 100 bases:

>100_bases
ATACAAAGTATTTTATGATTTAACAGGAAATAATTTCACGGCTAAGGAAGTGGTTGGCGGTGAGTGAATTTGAATCAGGT
AAAGAACAACGAGGTTGAAT

Downstream 100 bases:

>100_bases
CGGCTCTCACTCGCCTGAATCACTGCTCATCAGGACTCATTCGTTTGCTGCCTTGCTGCAACGCCAATGACGTTGGGGAT
CCCCTTTTTTACTTGATGCC

Product: methylthioribose kinase

Products: NA

Alternate protein names: MTR kinase

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSRYHTFTAADAVEYARQFGQVADPQALVTADEIGDGNLNLVFKIRDTAGISRVIVKQALPYVRCVGESWPLTLDRARIE
AETLLTHSQFCPQHTVKVLHHDAELAVMVQEDLSDHHIWRHELIQGNYYPQAAEQLGEYLAQTLFHTSDFYQSAQAKKAA
VSRYTNPELCQITEDLFFTDPYIDHERNNFDPVLLPEVLSLRQDKALKLAVASLKHRFLSQAEALLHGDIHSGSIFVADG
RLKTIDAEFGFYGPIGFDIGTALGNLLLNYCGLPGLAGPRDAAAGREQRLKDVQTVWQTFAARFLALSQEKAQDPALATE
GYAAQFLQHVWRDAIGYCGSELIRRTIGLAHVADLDSIDDEEMRRACQRHALSLGRALILVAPHVDDVGGVVARIRQSPS
SLTPQRC

Sequences:

>Translated_407_residues
MSRYHTFTAADAVEYARQFGQVADPQALVTADEIGDGNLNLVFKIRDTAGISRVIVKQALPYVRCVGESWPLTLDRARIE
AETLLTHSQFCPQHTVKVLHHDAELAVMVQEDLSDHHIWRHELIQGNYYPQAAEQLGEYLAQTLFHTSDFYQSAQAKKAA
VSRYTNPELCQITEDLFFTDPYIDHERNNFDPVLLPEVLSLRQDKALKLAVASLKHRFLSQAEALLHGDIHSGSIFVADG
RLKTIDAEFGFYGPIGFDIGTALGNLLLNYCGLPGLAGPRDAAAGREQRLKDVQTVWQTFAARFLALSQEKAQDPALATE
GYAAQFLQHVWRDAIGYCGSELIRRTIGLAHVADLDSIDDEEMRRACQRHALSLGRALILVAPHVDDVGGVVARIRQSPS
SLTPQRC
>Mature_406_residues
SRYHTFTAADAVEYARQFGQVADPQALVTADEIGDGNLNLVFKIRDTAGISRVIVKQALPYVRCVGESWPLTLDRARIEA
ETLLTHSQFCPQHTVKVLHHDAELAVMVQEDLSDHHIWRHELIQGNYYPQAAEQLGEYLAQTLFHTSDFYQSAQAKKAAV
SRYTNPELCQITEDLFFTDPYIDHERNNFDPVLLPEVLSLRQDKALKLAVASLKHRFLSQAEALLHGDIHSGSIFVADGR
LKTIDAEFGFYGPIGFDIGTALGNLLLNYCGLPGLAGPRDAAAGREQRLKDVQTVWQTFAARFLALSQEKAQDPALATEG
YAAQFLQHVWRDAIGYCGSELIRRTIGLAHVADLDSIDDEEMRRACQRHALSLGRALILVAPHVDDVGGVVARIRQSPSS
LTPQRC

Specific function: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate

COG id: COG4857

COG function: function code R; Predicted kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methylthioribose kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNK_YERP3 (A7FLL0)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402138.1
- ProteinModelPortal:   A7FLL0
- SMR:   A7FLL0
- STRING:   A7FLL0
- GeneID:   5387064
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3178
- NMPDR:   fig|349747.3.peg.3527
- eggNOG:   COG4857
- HOGENOM:   HBG305135
- OMA:   ALPYVRL
- ProtClustDB:   PRK09550
- BioCyc:   YPSE349747:YPSIP31758_3178-MONOMER
- HAMAP:   MF_01683
- InterPro:   IPR002575
- InterPro:   IPR011009
- InterPro:   IPR009212
- PIRSF:   PIRSF031134
- TIGRFAMs:   TIGR01767

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.100

Molecular weight: Translated: 45255; Mature: 45123

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: BINDING 40-40 BINDING 57-57 BINDING 229-229 BINDING 344-344

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYHTFTAADAVEYARQFGQVADPQALVTADEIGDGNLNLVFKIRDTAGISRVIVKQAL
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHCCCCCCEEEEEEECCCCCHHHHHHHHHC
PYVRCVGESWPLTLDRARIEAETLLTHSQFCPQHTVKVLHHDAELAVMVQEDLSDHHIWR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEHHCCCCHHHHH
HELIQGNYYPQAAEQLGEYLAQTLFHTSDFYQSAQAKKAAVSRYTNPELCQITEDLFFTD
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
PYIDHERNNFDPVLLPEVLSLRQDKALKLAVASLKHRFLSQAEALLHGDIHSGSIFVADG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
RLKTIDAEFGFYGPIGFDIGTALGNLLLNYCGLPGLAGPRDAAAGREQRLKDVQTVWQTF
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHH
AARFLALSQEKAQDPALATEGYAAQFLQHVWRDAIGYCGSELIRRTIGLAHVADLDSIDD
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EEMRRACQRHALSLGRALILVAPHVDDVGGVVARIRQSPSSLTPQRC
HHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SRYHTFTAADAVEYARQFGQVADPQALVTADEIGDGNLNLVFKIRDTAGISRVIVKQAL
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHCCCCCCEEEEEEECCCCCHHHHHHHHHC
PYVRCVGESWPLTLDRARIEAETLLTHSQFCPQHTVKVLHHDAELAVMVQEDLSDHHIWR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEHHCCCCHHHHH
HELIQGNYYPQAAEQLGEYLAQTLFHTSDFYQSAQAKKAAVSRYTNPELCQITEDLFFTD
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
PYIDHERNNFDPVLLPEVLSLRQDKALKLAVASLKHRFLSQAEALLHGDIHSGSIFVADG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
RLKTIDAEFGFYGPIGFDIGTALGNLLLNYCGLPGLAGPRDAAAGREQRLKDVQTVWQTF
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHH
AARFLALSQEKAQDPALATEGYAAQFLQHVWRDAIGYCGSELIRRTIGLAHVADLDSIDD
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EEMRRACQRHALSLGRALILVAPHVDDVGGVVARIRQSPSSLTPQRC
HHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA