Click here to switch to the map view.

The map label for this gene is dppD [H]

Identifier: 153947272

GI number: 153947272

Start: 4015812

End: 4016690

Strand: Direct

Name: dppD [H]

Synonym: YpsIP31758_3554

Alternate gene names: 153947272

Gene position: 4015812-4016690 (Clockwise)

Preceding gene: 153950409

Following gene: 153947737

Centisome position: 85.02

GC content: 51.31

Gene sequence:

>879_bases
ATGACTGATTCTATTTTTACCGTCGATAACCTGTGCGTCGATTTTCAGCAACAGCGGGTGGTGGATAACATTTCGTTCCA
CCTCGGTCACGAACGTGTTGCTCTCGTAGGCGAATCCGGCTCCGGGAAATCGATCACGGCCAGAGCGCTGATGGGCTTAG
TCAGGCACCCCGGTAAAGTCAGTGCCAAGAAGCTGAGTTATTACTCTGACAACACGGATGATCAGGGCCATTCCGGTCAG
ATTATTGAACACGATTTACTGCGCCTAAACACCAGGCAATGGAGCGCATTACGGGGCAGTGAAATTGCTATGGTGTTACA
AGACCCCCGTTATGCCTTAAATCCGGTACAACCTGTTGGTAAGCAGATTGAAGAGTCTCTGTTGCTGCATAACACCCTTT
CAAGCGCTGATGCGCATGAACGGGTATTAAATGCACTGGCCTCGGTTGGGTTAAATGCCAGCGCTTACCACAGCTACCCC
GGCCAGCTTTCTGGTGGTATGGGGCAACGCGCGATGCTGGCAATCGCTTTGGTGAATAATCCCAGAGTATTAATTGCCGA
TGAACCGACATCCGCGTTAGATGCCAAATTACGCAACCAGATCCTTGAATTAATTGTTGAGCAAACCGAACAACGAAAAA
TGAGCCTGTTGCTGATCAGCCATGACCTGCCATTAGTCGCCGAACATTGTCATCGCGTGTTAGTGATGTATCAGGGGAAG
TTGGTCGATCAAGGTCTGGCCGCTGATCTGCCCCATTCAACCCACCCTTATACCCACACGCTATGGGCTTGCCGCCCGAA
TGCCCATACCTATGGCACCGATCTGCCGGTATTGGATCGCAGCGTAGATTTCTCCGGAGGCTCCCGTGGCACTGATTGA

Upstream 100 bases:

>100_bases
CAATGGTGGATTGCGGCCATTCCCGGTTGTGCGATCCTACTCAGCAGCATGGCCTTTAACCTGTTAGGCGATGGCCTACG
CGATATTCTGGATCCTCACC

Downstream 100 bases:

>100_bases
AGTGAACAATTTGCAGGTCAGCTTTGCCCAGAAGAACCAGATCAAAACAGCGGTTGAATCGGTCAGTTTTGCGGTTGAAG
CCAATGAAACATTCAGCCTG

Product: dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTDSIFTVDNLCVDFQQQRVVDNISFHLGHERVALVGESGSGKSITARALMGLVRHPGKVSAKKLSYYSDNTDDQGHSGQ
IIEHDLLRLNTRQWSALRGSEIAMVLQDPRYALNPVQPVGKQIEESLLLHNTLSSADAHERVLNALASVGLNASAYHSYP
GQLSGGMGQRAMLAIALVNNPRVLIADEPTSALDAKLRNQILELIVEQTEQRKMSLLLISHDLPLVAEHCHRVLVMYQGK
LVDQGLAADLPHSTHPYTHTLWACRPNAHTYGTDLPVLDRSVDFSGGSRGTD

Sequences:

>Translated_292_residues
MTDSIFTVDNLCVDFQQQRVVDNISFHLGHERVALVGESGSGKSITARALMGLVRHPGKVSAKKLSYYSDNTDDQGHSGQ
IIEHDLLRLNTRQWSALRGSEIAMVLQDPRYALNPVQPVGKQIEESLLLHNTLSSADAHERVLNALASVGLNASAYHSYP
GQLSGGMGQRAMLAIALVNNPRVLIADEPTSALDAKLRNQILELIVEQTEQRKMSLLLISHDLPLVAEHCHRVLVMYQGK
LVDQGLAADLPHSTHPYTHTLWACRPNAHTYGTDLPVLDRSVDFSGGSRGTD
>Mature_291_residues
TDSIFTVDNLCVDFQQQRVVDNISFHLGHERVALVGESGSGKSITARALMGLVRHPGKVSAKKLSYYSDNTDDQGHSGQI
IEHDLLRLNTRQWSALRGSEIAMVLQDPRYALNPVQPVGKQIEESLLLHNTLSSADAHERVLNALASVGLNASAYHSYPG
QLSGGMGQRAMLAIALVNNPRVLIADEPTSALDAKLRNQILELIVEQTEQRKMSLLLISHDLPLVAEHCHRVLVMYQGKL
VDQGLAADLPHSTHPYTHTLWACRPNAHTYGTDLPVLDRSVDFSGGSRGTD

Specific function: Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system [H]

COG id: COG0444

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955968, Length=235, Percent_Identity=31.4893617021277, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI9955966, Length=235, Percent_Identity=31.4893617021277, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI45243524, Length=235, Percent_Identity=31.4893617021277, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789963, Length=272, Percent_Identity=41.9117647058824, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI145693107, Length=282, Percent_Identity=41.8439716312057, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1788506, Length=275, Percent_Identity=39.6363636363636, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI48994883, Length=281, Percent_Identity=36.2989323843416, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1787759, Length=292, Percent_Identity=33.5616438356164, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789962, Length=250, Percent_Identity=36.4, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787500, Length=251, Percent_Identity=36.6533864541833, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1787548, Length=287, Percent_Identity=31.3588850174216, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787758, Length=305, Percent_Identity=29.1803278688525, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1789891, Length=229, Percent_Identity=36.2445414847162, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787547, Length=274, Percent_Identity=29.5620437956204, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789890, Length=263, Percent_Identity=32.6996197718631, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87081834, Length=251, Percent_Identity=33.0677290836653, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788225, Length=254, Percent_Identity=31.8897637795276, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994997, Length=266, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789873, Length=225, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786398, Length=241, Percent_Identity=30.7053941908714, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789032, Length=235, Percent_Identity=31.063829787234, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789672, Length=259, Percent_Identity=28.1853281853282, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789991, Length=228, Percent_Identity=32.0175438596491, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786703, Length=216, Percent_Identity=32.4074074074074, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786872, Length=208, Percent_Identity=29.8076923076923, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787029, Length=242, Percent_Identity=26.8595041322314, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788644, Length=118, Percent_Identity=36.4406779661017, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87081709, Length=254, Percent_Identity=30.7086614173228, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788761, Length=248, Percent_Identity=30.6451612903226, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081791, Length=256, Percent_Identity=30.46875, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787712, Length=235, Percent_Identity=28.5106382978723, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787105, Length=276, Percent_Identity=27.536231884058, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786253, Length=91, Percent_Identity=41.7582417582418, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790162, Length=249, Percent_Identity=28.5140562248996, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787370, Length=135, Percent_Identity=34.8148148148148, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787089, Length=231, Percent_Identity=29.8701298701299, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786345, Length=111, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788450, Length=233, Percent_Identity=28.3261802575107, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787164, Length=104, Percent_Identity=38.4615384615385, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082267, Length=212, Percent_Identity=30.6603773584906, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787182, Length=249, Percent_Identity=26.5060240963855, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994943, Length=245, Percent_Identity=24.4897959183673, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790190, Length=110, Percent_Identity=31.8181818181818, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=245, Percent_Identity=29.3877551020408, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=248, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17569145, Length=253, Percent_Identity=27.6679841897233, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17511077, Length=219, Percent_Identity=29.6803652968037, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28574744, Length=244, Percent_Identity=24.5901639344262, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17136662, Length=240, Percent_Identity=30, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 32020; Mature: 31889

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSIFTVDNLCVDFQQQRVVDNISFHLGHERVALVGESGSGKSITARALMGLVRHPGKV
CCCCEEEHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCCCC
SAKKLSYYSDNTDDQGHSGQIIEHDLLRLNTRQWSALRGSEIAMVLQDPRYALNPVQPVG
CHHHEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCEEEEEEECCCCCCCCCCHHH
KQIEESLLLHNTLSSADAHERVLNALASVGLNASAYHSYPGQLSGGMGQRAMLAIALVNN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCEEEEEEEECC
PRVLIADEPTSALDAKLRNQILELIVEQTEQRKMSLLLISHDLPLVAEHCHRVLVMYQGK
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHEEHHHCCC
LVDQGLAADLPHSTHPYTHTLWACRPNAHTYGTDLPVLDRSVDFSGGSRGTD
HHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDSIFTVDNLCVDFQQQRVVDNISFHLGHERVALVGESGSGKSITARALMGLVRHPGKV
CCCEEEHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCCCC
SAKKLSYYSDNTDDQGHSGQIIEHDLLRLNTRQWSALRGSEIAMVLQDPRYALNPVQPVG
CHHHEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCEEEEEEECCCCCCCCCCHHH
KQIEESLLLHNTLSSADAHERVLNALASVGLNASAYHSYPGQLSGGMGQRAMLAIALVNN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCEEEEEEEECC
PRVLIADEPTSALDAKLRNQILELIVEQTEQRKMSLLLISHDLPLVAEHCHRVLVMYQGK
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHEEHHHCCC
LVDQGLAADLPHSTHPYTHTLWACRPNAHTYGTDLPVLDRSVDFSGGSRGTD
HHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]