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The map label for this gene is dsbB [H]

Identifier: 153946999

GI number: 153946999

Start: 2305846

End: 2306391

Strand: Direct

Name: dsbB [H]

Synonym: YpsIP31758_2001

Alternate gene names: 153946999

Gene position: 2305846-2306391 (Clockwise)

Preceding gene: 153948432

Following gene: 153948168

Centisome position: 48.82

GC content: 45.6

Gene sequence:

>546_bases
ATGGAAAATAAAGATATGTTGCAATTCCTTAACCGCTGTTCCCGAGGACGCGGTGCTTGGCTATTAATGGCCCTGACTGC
ATTTCTATTAGAGTTAACTGCGCTCTATTTTCAACACATTATGTTGCTACAACCGTGTGTAATGTGTATTTATGAGCGTG
TCGCATTATTCGGTATTCTCGGTGCATCACTATTGGGTGCAATAGCCCCGAGATCACCACTACGCTATTTAGCTATTGCA
GTTTGGATCTACAGCGCGTGGAAAGGGGTTCAGCTAGCTTGGGCACACACTATGCTGCAGTTGAATCCATCCCCATTTAA
CACCTGCGATTTCTTCGTCAACTTCCCTTCATGGCTACCCTTGGATAAATGGTTACCCGCCGTGTTCGCCGCCAGTGGCG
ATTGCTCGGAAAGACAATGGCAGTTTATGTCATTAGAAATGCCACAATGGTTAGTCGGTATTTTTGCTGCATATCTGGTT
ATCGCCGTACTCGTTCTGATCAGCCAATTTGTTAAACCTAAAAGACGCGATCTGTTCGGCCGATAA

Upstream 100 bases:

>100_bases
TGTCTTGTGCGGGAAAAAACTGATTTTTACCTAATTTTGCTTTTGGGTAGCTGGCAGAAAAGATGAATTGGTTTACACTG
CCGGTACAATTGCTTACTGC

Downstream 100 bases:

>100_bases
TTTTTATACATATCTTTATTATCAATGGCGCCTCTCTGGCGCCATTTTTATATCAGATTCAAACGGTCTGTTAATCCTAA
TGAACACTTAATTCCATGCA

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MENKDMLQFLNRCSRGRGAWLLMALTAFLLELTALYFQHIMLLQPCVMCIYERVALFGILGASLLGAIAPRSPLRYLAIA
VWIYSAWKGVQLAWAHTMLQLNPSPFNTCDFFVNFPSWLPLDKWLPAVFAASGDCSERQWQFMSLEMPQWLVGIFAAYLV
IAVLVLISQFVKPKRRDLFGR

Sequences:

>Translated_181_residues
MENKDMLQFLNRCSRGRGAWLLMALTAFLLELTALYFQHIMLLQPCVMCIYERVALFGILGASLLGAIAPRSPLRYLAIA
VWIYSAWKGVQLAWAHTMLQLNPSPFNTCDFFVNFPSWLPLDKWLPAVFAASGDCSERQWQFMSLEMPQWLVGIFAAYLV
IAVLVLISQFVKPKRRDLFGR
>Mature_181_residues
MENKDMLQFLNRCSRGRGAWLLMALTAFLLELTALYFQHIMLLQPCVMCIYERVALFGILGASLLGAIAPRSPLRYLAIA
VWIYSAWKGVQLAWAHTMLQLNPSPFNTCDFFVNFPSWLPLDKWLPAVFAASGDCSERQWQFMSLEMPQWLVGIFAAYLV
IAVLVLISQFVKPKRRDLFGR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein [H]

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family [H]

Homologues:

Organism=Escherichia coli, GI1787433, Length=176, Percent_Identity=73.2954545454545, Blast_Score=281, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003752
- InterPro:   IPR022920 [H]

Pfam domain/function: PF02600 DsbB [H]

EC number: NA

Molecular weight: Translated: 20725; Mature: 20725

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKDMLQFLNRCSRGRGAWLLMALTAFLLELTALYFQHIMLLQPCVMCIYERVALFGIL
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASLLGAIAPRSPLRYLAIAVWIYSAWKGVQLAWAHTMLQLNPSPFNTCDFFVNFPSWLP
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHEEECCCCCC
LDKWLPAVFAASGDCSERQWQFMSLEMPQWLVGIFAAYLVIAVLVLISQFVKPKRRDLFG
HHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
R
C
>Mature Secondary Structure
MENKDMLQFLNRCSRGRGAWLLMALTAFLLELTALYFQHIMLLQPCVMCIYERVALFGIL
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASLLGAIAPRSPLRYLAIAVWIYSAWKGVQLAWAHTMLQLNPSPFNTCDFFVNFPSWLP
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHEEECCCCCC
LDKWLPAVFAASGDCSERQWQFMSLEMPQWLVGIFAAYLVIAVLVLISQFVKPKRRDLFG
HHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA