BacMap

Definition	Yersinia pseudotuberculosis IP 31758, complete genome.
Accession	NC_009708
Length	4,723,306

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The map label for this gene is idnO [H]

Identifier: 153946945

GI number: 153946945

Start: 1711430

End: 1712194

Strand: Reverse

Name: idnO [H]

Synonym: YpsIP31758_1470

Alternate gene names: 153946945

Gene position: 1712194-1711430 (Counterclockwise)

Preceding gene: 153947145

Following gene: 153947375

Centisome position: 36.25

GC content: 44.18

Gene sequence:

>765_bases
ATGAAGAATCTATTTTCGTTGGAAAGTCGCAAAGTATTAATTACTGGCTCCGCACAGGGTATTGGATTCTTACTGGCAAA
AGGGTTAGCTGAATTTGGCGCAGAGATTATCATTAACGATATCACCGCAGAGCGTGCTGAAAAAGCCGTGGCTGAATTAC
GTGCTAGCGGCTTTATCGCCCATGCCGCCGCATTTAACGTGACGAACCATGATGAAGTCAATGAAGCTATCGAGAAAATA
GAAAGCCATATTGGTGCTATCGACGTGTTAATTAATAATGCAGGTATCCAACGCCGCCATGCCTTTACCGAATTCCCAGA
AAAAGATTGGGATGATGTGATTGCTGTTAATCAAAAATCGGTATTTTTAGTTTCACAAGCCGTTGCCCGTTATATGGTTA
AACGCCAACGTGGAAAAATTATTAATATCTGTTCAATGCAAAGTGAATTAGGCCGCGATACGATCACCCCATATGCCGCC
TCTAAAGGGGCAGTTAAAATGCTGACCCGTGGGATGTGTGTCGAACTGGCTCGCTACAATATTCAGGTTAACGGTATTGC
GCCGGGTTATTTCAAAACGGATATGACAAAAGCACTGGTCGATGATCAAGCCTTTACCGATTGGTTATGTAAACGCACAC
CTGCCGCCCGTTGGGGAGATCCAGAAGAGCTTATTGGTGCAGCGGTTTATTTGTCATCCAAAGCCTCTGACTTTGTTAAT
GGTCATTTGCTGTTTGTTGATGGTGGCATGCTGGTAGCCGTTTAA

Upstream 100 bases:

>100_bases
TGTATTTACGGCGTCTTTACGATCTGCCTGTTCTCTCCGTCGCGGGCACTTTGTCAATAGCCTCATTATTTTTATATATT
ATCGCTATCAGGAAATGACC

Downstream 100 bases:

>100_bases
TCCAGGGTTCAGTCGTACTCCCCACATAATGGGGAGCAGAGGAAAATTATGTCTGGTAAATGCATTATTGTCATGGGTGT
CTCTGGTACCGGTAAATCCT

Product: gluconate 5-dehydrogenase

Products: NA

Alternate protein names: 5-keto-D-gluconate 5-reductase [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKNLFSLESRKVLITGSAQGIGFLLAKGLAEFGAEIIINDITAERAEKAVAELRASGFIAHAAAFNVTNHDEVNEAIEKI
ESHIGAIDVLINNAGIQRRHAFTEFPEKDWDDVIAVNQKSVFLVSQAVARYMVKRQRGKIINICSMQSELGRDTITPYAA
SKGAVKMLTRGMCVELARYNIQVNGIAPGYFKTDMTKALVDDQAFTDWLCKRTPAARWGDPEELIGAAVYLSSKASDFVN
GHLLFVDGGMLVAV

Sequences:

>Translated_254_residues
MKNLFSLESRKVLITGSAQGIGFLLAKGLAEFGAEIIINDITAERAEKAVAELRASGFIAHAAAFNVTNHDEVNEAIEKI
ESHIGAIDVLINNAGIQRRHAFTEFPEKDWDDVIAVNQKSVFLVSQAVARYMVKRQRGKIINICSMQSELGRDTITPYAA
SKGAVKMLTRGMCVELARYNIQVNGIAPGYFKTDMTKALVDDQAFTDWLCKRTPAARWGDPEELIGAAVYLSSKASDFVN
GHLLFVDGGMLVAV
>Mature_254_residues
MKNLFSLESRKVLITGSAQGIGFLLAKGLAEFGAEIIINDITAERAEKAVAELRASGFIAHAAAFNVTNHDEVNEAIEKI
ESHIGAIDVLINNAGIQRRHAFTEFPEKDWDDVIAVNQKSVFLVSQAVARYMVKRQRGKIINICSMQSELGRDTITPYAA
SKGAVKMLTRGMCVELARYNIQVNGIAPGYFKTDMTKALVDDQAFTDWLCKRTPAARWGDPEELIGAAVYLSSKASDFVN
GHLLFVDGGMLVAV

Specific function: Catalyzes a reversible reduction of 5-ketoglutanate to form D-gluconate. Dependent on NADP, almost inactive with NAD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=33.2046332046332, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=28.6885245901639, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI40254992, Length=237, Percent_Identity=31.2236286919831, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=30.0411522633745, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=30, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=29.5081967213115, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=27.5303643724696, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=31.9587628865979, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI4504505, Length=235, Percent_Identity=29.3617021276596, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=29.3333333333333, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=29.3172690763052, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=26.8774703557312, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI210032110, Length=189, Percent_Identity=26.4550264550265, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=28.90625, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI4503301, Length=227, Percent_Identity=24.2290748898678, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=27.9329608938547, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=28.0612244897959, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI109715829, Length=200, Percent_Identity=28.5, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI142976729, Length=246, Percent_Identity=22.7642276422764, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40807363, Length=188, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=26.3414634146341, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI209862901, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI19923983, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI19743808, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=23.7373737373737, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI40254986, Length=213, Percent_Identity=29.1079812206573, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI83715985, Length=257, Percent_Identity=28.0155642023346, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI22507405, Length=193, Percent_Identity=29.0155440414508, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4503817, Length=206, Percent_Identity=23.3009708737864, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=79.1338582677165, Blast_Score=423, Evalue=1e-120,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=39.6, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=41.1290322580645, Blast_Score=180, Evalue=6e-47,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=35.6275303643725, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=34.4, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=35.3909465020576, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=34.9794238683128, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=31.3008130081301, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=25.0996015936255, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=24.1106719367589, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=26.0162601626016, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=34.9593495934959, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=34.1463414634146, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=28.1632653061224, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=32.1138211382114, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=28.2352941176471, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI193203117, Length=194, Percent_Identity=26.8041237113402, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=27.979274611399, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193203115, Length=188, Percent_Identity=27.6595744680851, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17568967, Length=211, Percent_Identity=30.3317535545024, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=27.7992277992278, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=28.3018867924528, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=25.9842519685039, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=253, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=26.7716535433071, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=28.3524904214559, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=24.4, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=24.8, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=169, Percent_Identity=29.585798816568, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17561272, Length=233, Percent_Identity=26.1802575107296, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=27.2030651340996, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=27.6923076923077, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=272, Percent_Identity=26.8382352941176, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=29.7709923664122, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=26.5384615384615, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=27.34375, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=258, Percent_Identity=26.7441860465116, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=26.2357414448669, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=254, Percent_Identity=28.3464566929134, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=28.1368821292776, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=253, Percent_Identity=26.4822134387352, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=255, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71997099, Length=226, Percent_Identity=29.2035398230088, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32563809, Length=217, Percent_Identity=27.1889400921659, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17507613, Length=211, Percent_Identity=27.0142180094787, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193210355, Length=196, Percent_Identity=27.0408163265306, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=257, Percent_Identity=26.0700389105058, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115534660, Length=207, Percent_Identity=27.536231884058, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86565303, Length=255, Percent_Identity=24.7058823529412, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=218, Percent_Identity=27.9816513761468, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=30.4347826086957, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=24.4, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=190, Percent_Identity=29.4736842105263, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=28.9340101522843, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=34.1269841269841, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=28.5714285714286, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=27.3809523809524, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=29.4820717131474, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=29.7619047619048, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24640492, Length=198, Percent_Identity=30.3030303030303, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24644339, Length=243, Percent_Identity=28.3950617283951, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI18859837, Length=211, Percent_Identity=29.8578199052133, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281364892, Length=191, Percent_Identity=30.8900523560209, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=28.4584980237154, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24644337, Length=173, Percent_Identity=30.635838150289, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357673, Length=243, Percent_Identity=27.9835390946502, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=27.6923076923077, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24581726, Length=198, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574402, Length=200, Percent_Identity=26.5, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584744, Length=200, Percent_Identity=26.5, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649181, Length=194, Percent_Identity=27.8350515463918, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580925, Length=231, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.69 [H]

Molecular weight: Translated: 27765; Mature: 27765

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLFSLESRKVLITGSAQGIGFLLAKGLAEFGAEIIINDITAERAEKAVAELRASGFIA
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCEE
HAAAFNVTNHDEVNEAIEKIESHIGAIDVLINNAGIQRRHAFTEFPEKDWDDVIAVNQKS
HHEEECCCCHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHCCCCCCCCCEEEECCCH
VFLVSQAVARYMVKRQRGKIINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARYN
HHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHE
IQVNGIAPGYFKTDMTKALVDDQAFTDWLCKRTPAARWGDPEELIGAAVYLSSKASDFVN
EEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHC
GHLLFVDGGMLVAV
CEEEEEECCEEEEC
>Mature Secondary Structure
MKNLFSLESRKVLITGSAQGIGFLLAKGLAEFGAEIIINDITAERAEKAVAELRASGFIA
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCEE
HAAAFNVTNHDEVNEAIEKIESHIGAIDVLINNAGIQRRHAFTEFPEKDWDDVIAVNQKS
HHEEECCCCHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHCCCCCCCCCEEEECCCH
VFLVSQAVARYMVKRQRGKIINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARYN
HHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHE
IQVNGIAPGYFKTDMTKALVDDQAFTDWLCKRTPAARWGDPEELIGAAVYLSSKASDFVN
EEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHC
GHLLFVDGGMLVAV
CEEEEEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]