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The map label for this gene is nudG [H]

Identifier: 153937421

GI number: 153937421

Start: 2149875

End: 2150273

Strand: Direct

Name: nudG [H]

Synonym: CLC_2027

Alternate gene names: 153937421

Gene position: 2149875-2150273 (Clockwise)

Preceding gene: 153937862

Following gene: 153935330

Centisome position: 57.17

GC content: 32.83

Gene sequence:

>399_bases
ATGAAAAAATTAGTAAAAGTTATTGGTGCTATTGTAGAAAATGAAAATAATGAAATACTTTGTGCTCTTCGTTCTCCAAG
AATGTCCCTTCCAAACATGTGGGAATTCCCTGGTGGTAAAATAGAAAAGGATGAAACTTTTAAACAAGCTATCGAAAGAG
AGATTAGTGAGGAATTATCCTGCAGGGTTGAATTTATAGATGTTTTTAATGATACTACTCACGAATACGATGAGATTATA
GTAAATTTAGTTACAGCTAGATGTAAACTAACATCTGATATACCAACAGCAAGTGAACATTCAAAATTAATATGGCTACA
TAGAGAAAATTTACTTTCCCTAGATTGGGCTCCGGCAGACATTCCTGCTGTAAAAAAACTTGTACAAGAAAAGGTATAG

Upstream 100 bases:

>100_bases
AATTATTGTTATCTTCTTTGTTTATCATTATTAGCTATCTCAAGTATCATTGCTACCAAAAAAAATTATTTTATGCTAAA
ATTATTTAGAGGTGTTTATT

Downstream 100 bases:

>100_bases
CAAATCATTGCTATACCTTTTTAACAAATTCATTATATAAATATGTTGGAACCTTATTGTATAATTTTATCTCAACAGTT
ATAGGCTTTTCTCCTTTATA

Product: putative mutator mutT protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MKKLVKVIGAIVENENNEILCALRSPRMSLPNMWEFPGGKIEKDETFKQAIEREISEELSCRVEFIDVFNDTTHEYDEII
VNLVTARCKLTSDIPTASEHSKLIWLHRENLLSLDWAPADIPAVKKLVQEKV

Sequences:

>Translated_132_residues
MKKLVKVIGAIVENENNEILCALRSPRMSLPNMWEFPGGKIEKDETFKQAIEREISEELSCRVEFIDVFNDTTHEYDEII
VNLVTARCKLTSDIPTASEHSKLIWLHRENLLSLDWAPADIPAVKKLVQEKV
>Mature_132_residues
MKKLVKVIGAIVENENNEILCALRSPRMSLPNMWEFPGGKIEKDETFKQAIEREISEELSCRVEFIDVFNDTTHEYDEII
VNLVTARCKLTSDIPTASEHSKLIWLHRENLLSLDWAPADIPAVKKLVQEKV

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=126, Percent_Identity=32.5396825396825, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786288, Length=127, Percent_Identity=33.8582677165354, Blast_Score=69, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 15163; Mature: 15163

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLVKVIGAIVENENNEILCALRSPRMSLPNMWEFPGGKIEKDETFKQAIEREISEELS
CHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
CRVEFIDVFNDTTHEYDEIIVNLVTARCKLTSDIPTASEHSKLIWLHRENLLSLDWAPAD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCCCC
IPAVKKLVQEKV
CHHHHHHHHHCC
>Mature Secondary Structure
MKKLVKVIGAIVENENNEILCALRSPRMSLPNMWEFPGGKIEKDETFKQAIEREISEELS
CHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
CRVEFIDVFNDTTHEYDEIIVNLVTARCKLTSDIPTASEHSKLIWLHRENLLSLDWAPAD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCCCC
IPAVKKLVQEKV
CHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]