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The map label for this gene is ykoH [H]

Identifier: 153937053

GI number: 153937053

Start: 2362557

End: 2363807

Strand: Reverse

Name: ykoH [H]

Synonym: CLC_2235

Alternate gene names: 153937053

Gene position: 2363807-2362557 (Counterclockwise)

Preceding gene: 153936330

Following gene: 153936787

Centisome position: 62.86

GC content: 29.34

Gene sequence:

>1251_bases
ATGAGTAGAAAAAATAAAACGAAAAATGTCATATCTATTGCAATAAAATTAAACTCTGTTTTTGTAAGAAATTTATTTTT
AAAGTTTCTTATCCTTGATATATGCATAATTGCTGGATTTATTGGAGTTTGGTGTATTGAAAATGAAATAAGTTTTTATG
GTGAGATCGTAAGAAATGCTCAAAGGTCATTTGAATTTTATCCTATAGAAGCAGCAAATTATAAAGTCATTTGGGATAAT
GGAAAGGTTATGATAAAAGAGGCTAGCACTTTTTTAAACCTTCTTATAAAAGTAATTAGCGCTATTGGAATTATAGAAGG
AATAATGCTATTAATGCAAATGATATTTGGTACTGCAAAAAATAGAATGATTTTAAAACCACTTAATGAAATAGCAGAAG
CTGCAAGTAGGCTTAGTGATATGGCTTTTGATGAGCAAAAATTTCAAAGTCTTGAGGATGCTATATCTAAAATAAGTCCT
GCTACATCTGATGAAAGAATTCATATTAAAGATAGTGAACTTCAGGGTTTAGAGGAAGCAATTAATAACCTATTAGATAG
AATGAGAGATTCTTATAGGCAACAAGCAAGATTTGTTTCAGATGCATCCCATGAACTTAGAACTCCTATATCTGTAATTC
AAGGGTATGCTAATATGTTAGATCGTTGGGGAAAAGATGATGAAGAAGTATTAGAGGAATCTATTGCAGCCATAAAGAGT
GAATCAGAAAATATGAAAAACTTAGTAGAACAGTTATTATTTTTAGCCAGGGGTATTAATGGTAAAACTCAACTTAAGGT
TATGGAATTTTCACTTAATGATATGATGAAAGAGGTTTTAGAAGAATCTAAGATGATAGATAAAGATCATATATATAGAT
ATATAGATTCAGAAAATATAAATGTTTATGGTGATATATCATTACTCAAACAAACAGCTAGAATATTAATAGAAAATGCA
GCAAAGTATACAGATAAAGGTGAAGATATAATACTAAGAACAGGGAAAAATAATAAAAATGAGCCCTATTTTTCTATTCA
AGATAATGGAATAGGCATGGATGAGAATGATGTATTACACATGTTTGAACGTTTTTTCAGAGCTGATACTGCAAGAGTTA
GAAAAAATGGTGGTACAGGGCTAGGTCTTTCCATTGCTAAATGGATTATTGATAGTCATAAAGGATATTTTAGCGTTTTA
AGTAGGAAAGAAATAGGTACAAGAATAACTGTTTTTTTACCTAAAAGATAG

Upstream 100 bases:

>100_bases
GTTATAGATGTTTATATAAGATTTTTAAGAACAAAAATAGATGATGCTTTTAAGGCTAAAATAATAACTACAGTTCGTGG
TGTGGGATACGTAATTAAAG

Downstream 100 bases:

>100_bases
TAAAAGCTTTCTATGATTTATTATTTTATCATGGAAAGCCTTTTAGATGTTGAATTTATAGATTATTAATATGTTAGTTA
TTATTATGAAGATCTTGTTT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MSRKNKTKNVISIAIKLNSVFVRNLFLKFLILDICIIAGFIGVWCIENEISFYGEIVRNAQRSFEFYPIEAANYKVIWDN
GKVMIKEASTFLNLLIKVISAIGIIEGIMLLMQMIFGTAKNRMILKPLNEIAEAASRLSDMAFDEQKFQSLEDAISKISP
ATSDERIHIKDSELQGLEEAINNLLDRMRDSYRQQARFVSDASHELRTPISVIQGYANMLDRWGKDDEEVLEESIAAIKS
ESENMKNLVEQLLFLARGINGKTQLKVMEFSLNDMMKEVLEESKMIDKDHIYRYIDSENINVYGDISLLKQTARILIENA
AKYTDKGEDIILRTGKNNKNEPYFSIQDNGIGMDENDVLHMFERFFRADTARVRKNGGTGLGLSIAKWIIDSHKGYFSVL
SRKEIGTRITVFLPKR

Sequences:

>Translated_416_residues
MSRKNKTKNVISIAIKLNSVFVRNLFLKFLILDICIIAGFIGVWCIENEISFYGEIVRNAQRSFEFYPIEAANYKVIWDN
GKVMIKEASTFLNLLIKVISAIGIIEGIMLLMQMIFGTAKNRMILKPLNEIAEAASRLSDMAFDEQKFQSLEDAISKISP
ATSDERIHIKDSELQGLEEAINNLLDRMRDSYRQQARFVSDASHELRTPISVIQGYANMLDRWGKDDEEVLEESIAAIKS
ESENMKNLVEQLLFLARGINGKTQLKVMEFSLNDMMKEVLEESKMIDKDHIYRYIDSENINVYGDISLLKQTARILIENA
AKYTDKGEDIILRTGKNNKNEPYFSIQDNGIGMDENDVLHMFERFFRADTARVRKNGGTGLGLSIAKWIIDSHKGYFSVL
SRKEIGTRITVFLPKR
>Mature_415_residues
SRKNKTKNVISIAIKLNSVFVRNLFLKFLILDICIIAGFIGVWCIENEISFYGEIVRNAQRSFEFYPIEAANYKVIWDNG
KVMIKEASTFLNLLIKVISAIGIIEGIMLLMQMIFGTAKNRMILKPLNEIAEAASRLSDMAFDEQKFQSLEDAISKISPA
TSDERIHIKDSELQGLEEAINNLLDRMRDSYRQQARFVSDASHELRTPISVIQGYANMLDRWGKDDEEVLEESIAAIKSE
SENMKNLVEQLLFLARGINGKTQLKVMEFSLNDMMKEVLEESKMIDKDHIYRYIDSENINVYGDISLLKQTARILIENAA
KYTDKGEDIILRTGKNNKNEPYFSIQDNGIGMDENDVLHMFERFFRADTARVRKNGGTGLGLSIAKWIIDSHKGYFSVLS
RKEIGTRITVFLPKR

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=30.4545454545455, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786783, Length=244, Percent_Identity=29.0983606557377, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790551, Length=322, Percent_Identity=27.3291925465839, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788393, Length=296, Percent_Identity=25, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=28.5106382978723, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789149, Length=265, Percent_Identity=28.3018867924528, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788549, Length=266, Percent_Identity=25.5639097744361, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=26.6393442622951, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788279, Length=246, Percent_Identity=28.4552845528455, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1789808, Length=246, Percent_Identity=26.4227642276423, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=273, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789403, Length=230, Percent_Identity=27.3913043478261, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=27.0742358078603, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=26.7543859649123, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081816, Length=365, Percent_Identity=23.8356164383562, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=25.2212389380531, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082128, Length=295, Percent_Identity=24.7457627118644, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=22.7467811158798, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47585; Mature: 47453

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKNKTKNVISIAIKLNSVFVRNLFLKFLILDICIIAGFIGVWCIENEISFYGEIVRNA
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRSFEFYPIEAANYKVIWDNGKVMIKEASTFLNLLIKVISAIGIIEGIMLLMQMIFGTAK
HHCCEEEEECCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NRMILKPLNEIAEAASRLSDMAFDEQKFQSLEDAISKISPATSDERIHIKDSELQGLEEA
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHH
INNLLDRMRDSYRQQARFVSDASHELRTPISVIQGYANMLDRWGKDDEEVLEESIAAIKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
ESENMKNLVEQLLFLARGINGKTQLKVMEFSLNDMMKEVLEESKMIDKDHIYRYIDSENI
CHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
NVYGDISLLKQTARILIENAAKYTDKGEDIILRTGKNNKNEPYFSIQDNGIGMDENDVLH
EEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHHH
MFERFFRADTARVRKNGGTGLGLSIAKWIIDSHKGYFSVLSRKEIGTRITVFLPKR
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure 
SRKNKTKNVISIAIKLNSVFVRNLFLKFLILDICIIAGFIGVWCIENEISFYGEIVRNA
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRSFEFYPIEAANYKVIWDNGKVMIKEASTFLNLLIKVISAIGIIEGIMLLMQMIFGTAK
HHCCEEEEECCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NRMILKPLNEIAEAASRLSDMAFDEQKFQSLEDAISKISPATSDERIHIKDSELQGLEEA
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHH
INNLLDRMRDSYRQQARFVSDASHELRTPISVIQGYANMLDRWGKDDEEVLEESIAAIKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
ESENMKNLVEQLLFLARGINGKTQLKVMEFSLNDMMKEVLEESKMIDKDHIYRYIDSENI
CHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
NVYGDISLLKQTARILIENAAKYTDKGEDIILRTGKNNKNEPYFSIQDNGIGMDENDVLH
EEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHHH
MFERFFRADTARVRKNGGTGLGLSIAKWIIDSHKGYFSVLSRKEIGTRITVFLPKR
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]