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The map label for this gene is manA [H]

Identifier: 153936592

GI number: 153936592

Start: 470547

End: 471527

Strand: Direct

Name: manA [H]

Synonym: CLC_0468

Alternate gene names: 153936592

Gene position: 470547-471527 (Clockwise)

Preceding gene: 153935762

Following gene: 153935517

Centisome position: 12.51

GC content: 27.32

Gene sequence:

>981_bases
ATGTACCCTTTAAAATTTGAAAACATATATTTAAATAAGGTGTGGGGAGGAAGAGGCTTAAAAAAATTTAGAGATAATCT
TCCTAAAGGTGATATAGGTGAAAGTTGGGATATAGCATTTCACCAAGATTTAATAAGTGTAATCAAAAATGGGAAACTTA
AGGGGAAGACATTAAAAGATGCTATAGAATTATATAAAAATAAATTAATGGGAGACTGCATATTTGATAAATATAAAGAT
TTTCCATTACTTTTAAAAATAATAAGTGCAGAAAAAAAATTGTCCATACAGGTACACCCAGGTGAAAAAGACTTTTTAGA
TTTAAAGGAAAGCCCTAAAAAAGAAGCCTGGTATGTTATGGAAGCTAAAGTGGGTTCCTATATAATTTTAGGTAGTAAAA
TAAAAGATAAAACTGTACTTAAACAGGTTATAGACGATGGCACAGTTGAAGATTATTTATATAAAGTACCAGTAAAGAAG
GGGGATATATTTTATATAGATAGTGGAATGATTCATGCTATAGGTAAAGGAGTTACATTAATTGAAATTCAACAGAACAG
CGATACAACTTATAGATTATATGATTATAATAGAGGAAGAAAACTAGATTTAGAAAAAGGAATGAATTGTGTAAATTTAG
ATATTAAACCTAATAAAAAATCAGGCTTAAAAGTGCAATTGAAAAATTGCAATAAAACTTATTGCTTTTTGTCAGAGGCT
TTTGCTATGGAAAAATATGAAGTATATTATTTTTTAAAAGAAAAAAGTGATAAAGAAAGATTTTTTATTTTTACCTGTGT
AGATGGACAAGGACAAATTAATTATGGTGAAGGACGACAAAATCTAAGTAGGGGAGATAGTATACTCATACCTGCTTATA
TGGGAGATTATACATTAAGAGGTAACATGAACTTATTGAAATTTTATATACCAGATATAGAAAAGTCCATTAATAGTATT
GTAAATATAATAAAATGTTAA

Upstream 100 bases:

>100_bases
AGGTGTGGGACAATAATCATTTATATATTTTTTATTTTAGAATATATATTAAATGTATCTAATATATATTAAGTGAATTA
ATTTATATTTAAGGAGAAAA

Downstream 100 bases:

>100_bases
ATAGATTTTATGTTATTAGATTAAAACAATAAAATTAAAAGAAGTATGTATTGTATAAAGAGAAATTTATAAATGATGTA
TAAAATAGGTTTGATTTTAG

Product: mannose-6-phosphate isomerase, class I

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MYPLKFENIYLNKVWGGRGLKKFRDNLPKGDIGESWDIAFHQDLISVIKNGKLKGKTLKDAIELYKNKLMGDCIFDKYKD
FPLLLKIISAEKKLSIQVHPGEKDFLDLKESPKKEAWYVMEAKVGSYIILGSKIKDKTVLKQVIDDGTVEDYLYKVPVKK
GDIFYIDSGMIHAIGKGVTLIEIQQNSDTTYRLYDYNRGRKLDLEKGMNCVNLDIKPNKKSGLKVQLKNCNKTYCFLSEA
FAMEKYEVYYFLKEKSDKERFFIFTCVDGQGQINYGEGRQNLSRGDSILIPAYMGDYTLRGNMNLLKFYIPDIEKSINSI
VNIIKC

Sequences:

>Translated_326_residues
MYPLKFENIYLNKVWGGRGLKKFRDNLPKGDIGESWDIAFHQDLISVIKNGKLKGKTLKDAIELYKNKLMGDCIFDKYKD
FPLLLKIISAEKKLSIQVHPGEKDFLDLKESPKKEAWYVMEAKVGSYIILGSKIKDKTVLKQVIDDGTVEDYLYKVPVKK
GDIFYIDSGMIHAIGKGVTLIEIQQNSDTTYRLYDYNRGRKLDLEKGMNCVNLDIKPNKKSGLKVQLKNCNKTYCFLSEA
FAMEKYEVYYFLKEKSDKERFFIFTCVDGQGQINYGEGRQNLSRGDSILIPAYMGDYTLRGNMNLLKFYIPDIEKSINSI
VNIIKC
>Mature_326_residues
MYPLKFENIYLNKVWGGRGLKKFRDNLPKGDIGESWDIAFHQDLISVIKNGKLKGKTLKDAIELYKNKLMGDCIFDKYKD
FPLLLKIISAEKKLSIQVHPGEKDFLDLKESPKKEAWYVMEAKVGSYIILGSKIKDKTVLKQVIDDGTVEDYLYKVPVKK
GDIFYIDSGMIHAIGKGVTLIEIQQNSDTTYRLYDYNRGRKLDLEKGMNCVNLDIKPNKKSGLKVQLKNCNKTYCFLSEA
FAMEKYEVYYFLKEKSDKERFFIFTCVDGQGQINYGEGRQNLSRGDSILIPAYMGDYTLRGNMNLLKFYIPDIEKSINSI
VNIIKC

Specific function: Involved In The Conversion Of Glucose To Gdp-L-Fucose, Which Can Be Converted To L-Fucose, A Capsular Polysaccharide. [C]

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 37578; Mature: 37578

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPLKFENIYLNKVWGGRGLKKFRDNLPKGDIGESWDIAFHQDLISVIKNGKLKGKTLKD
CCCEEECEEEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHH
AIELYKNKLMGDCIFDKYKDFPLLLKIISAEKKLSIQVHPGEKDFLDLKESPKKEAWYVM
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEE
EAKVGSYIILGSKIKDKTVLKQVIDDGTVEDYLYKVPVKKGDIFYIDSGMIHAIGKGVTL
EECCCCEEEECCCCCHHHHHHHHHCCCCHHHEEEECCCCCCCEEEECCCEEEECCCCEEE
IEIQQNSDTTYRLYDYNRGRKLDLEKGMNCVNLDIKPNKKSGLKVQLKNCNKTYCFLSEA
EEEECCCCCEEEEEECCCCCEEEHHHCCCEEEEEECCCCCCCCEEEEECCCCEEEEEHHH
FAMEKYEVYYFLKEKSDKERFFIFTCVDGQGQINYGEGRQNLSRGDSILIPAYMGDYTLR
HCCEEEEEEEEEECCCCCCEEEEEEEECCCCEEECCCCCCHHCCCCCEEEEEEECCEEEE
GNMNLLKFYIPDIEKSINSIVNIIKC
CCCEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MYPLKFENIYLNKVWGGRGLKKFRDNLPKGDIGESWDIAFHQDLISVIKNGKLKGKTLKD
CCCEEECEEEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHH
AIELYKNKLMGDCIFDKYKDFPLLLKIISAEKKLSIQVHPGEKDFLDLKESPKKEAWYVM
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEE
EAKVGSYIILGSKIKDKTVLKQVIDDGTVEDYLYKVPVKKGDIFYIDSGMIHAIGKGVTL
EECCCCEEEECCCCCHHHHHHHHHCCCCHHHEEEECCCCCCCEEEECCCEEEECCCCEEE
IEIQQNSDTTYRLYDYNRGRKLDLEKGMNCVNLDIKPNKKSGLKVQLKNCNKTYCFLSEA
EEEECCCCCEEEEEECCCCCEEEHHHCCCEEEEEECCCCCCCCEEEEECCCCEEEEEHHH
FAMEKYEVYYFLKEKSDKERFFIFTCVDGQGQINYGEGRQNLSRGDSILIPAYMGDYTLR
HCCEEEEEEEEEECCCCCCEEEEEEEECCCCEEECCCCCCHHCCCCCEEEEEEECCEEEE
GNMNLLKFYIPDIEKSINSIVNIIKC
CCCEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]