BacMap

Definition	Clostridium botulinum A str. Hall, complete genome.
Accession	NC_009698
Length	3,760,560

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The map label for this gene is 153936360

Identifier: 153936360

GI number: 153936360

Start: 2099337

End: 2100830

Strand: Reverse

Name: 153936360

Synonym: CLC_1979

Alternate gene names: NA

Gene position: 2100830-2099337 (Counterclockwise)

Preceding gene: 153934846

Following gene: 153935564

Centisome position: 55.86

GC content: 31.46

Gene sequence:

>1494_bases
ATGAAAAAATCCAGAGAACAATGGGGGACAAAAGCAGGGTTCCTACTTGCAGCTATTGGTTCTGCTGTAGGACTAGGTAA
TATATGGAGATTTCCTTATGTAGCTTATTCAAATGGAGGTGGAGCATTTTTAATACCATATTTTTTCGCTATATTTACAG
CAGGAATACCTTTATTAATTCTTGAATATGGAATGGGACATAAATTTAGAGGTTCAACACCACTAGCAATAGCAAGAGCA
AATAAAAAGTGGGAATGGCTTGGTTGGTGGCCTATAATTAGTGCAGTTATAATTTTATCCTATTATTCAATGATTTTGAG
TCTGGCTATGAAGTACTTAACATTAAGTTTTAATAAAGTATGGGGAAATGACACTAACAGTTATTTTTATGATGAAGTAT
TAAAAGTATCATCATCACCTTTTGATTTTAGAGGTATAATTATTCCAATACTAATAGGAATAACTTTAGTTTGGTTAATT
AACTGGTTTATATGTTATAAAGGAATAAAAGCTGGAATTGAAAAATTGAGTAAAATATTATTACCAGCTCTATTAATAAT
AATGATAATTATAGTAATAAAGGGGGTAACTTTAAAAGGGGCTTCTTTAGGTTTAAACACACTGTTTACACCTGATTGGA
AAAAAGTTAAAGATCCTAAAGTTTGGATTGCAGCATATGGACAAGTATTCTTTTCATTAAGCATAGCTACAGGGATCATG
ATGACTTATTCCAGTTATCTTCCTAAAAAAACAGATATAAATAATAGTGCATTCATGACTGCTTTTGCTAACTGTGGCTT
TGAATTTTTATCTGCCATAGGGGTTTTTGCAATACTTGGGTTCATGGCAACCAACCAAGGAGTATCTATTGATAAAGTTG
CATCTGGTGGTATAGGCCTTGCATTTATAGCATTCCCCAAAGTATTTTCAGTAATGGGCATCTGGGGAAACATACTATCT
GTATTATTCTTTACTTGCTTGATATTTGCAGGATTAACATCAGCAGTATCCTTAGTTGAGGCAATCTCCTCAGCCATAAT
AGATAAAACAGGATGGGAACGTAAAAAAGTAGTAACAGGAATTTTGTTAGTTGGATTTATTATAAGTATCTTATTTGCAA
CTAGAGCAGGATTATATCTATTAGATATTATGGACAACTTTATTAATAATTATGGAGTAGTTGTAGTTGGATTACTAGAA
ACTATTTTAGTAGGATGGATTGTAAAACCTGAAACCATTCGGGATCATACAAATTCAGTATCTTATTATAGAATAGGAAA
ATGGTGGGACATAATTATTAAATGTATAAATCCAATTGTTTTAACTTTCATTCTAGTACAAAGTTTTATTACAGAAATGC
GTACACCTTATGGTGGATATGATTTGCAGGCATTGTTTGTTTATGGATGGGGAGCTATTTTAATAGGGATTACTGGATCA
ATCTTAATAAGTAAACAACCTTGGAGAGATAATATTAATTTAAAAAATGAATAA

Upstream 100 bases:

>100_bases
ATCCTAGGTAAAAAAGTCTCATAGTATAAACTGTGGGGCTTTTTTATTTATAAATATCAATATTTGGAAAATCCAGATAA
ATAATTTAGGAGGAATAGAA

Downstream 100 bases:

>100_bases
AGGTGTGGTGATAAAAATGACATTAAGTGCAACGATATTTTTTGGTATAGGTGCAACCGTACTCTGGGGAGGATTATTGA
CTACTATAATAATTTCAATG

Product: sodium:neurotransmitter symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MKKSREQWGTKAGFLLAAIGSAVGLGNIWRFPYVAYSNGGGAFLIPYFFAIFTAGIPLLILEYGMGHKFRGSTPLAIARA
NKKWEWLGWWPIISAVIILSYYSMILSLAMKYLTLSFNKVWGNDTNSYFYDEVLKVSSSPFDFRGIIIPILIGITLVWLI
NWFICYKGIKAGIEKLSKILLPALLIIMIIIVIKGVTLKGASLGLNTLFTPDWKKVKDPKVWIAAYGQVFFSLSIATGIM
MTYSSYLPKKTDINNSAFMTAFANCGFEFLSAIGVFAILGFMATNQGVSIDKVASGGIGLAFIAFPKVFSVMGIWGNILS
VLFFTCLIFAGLTSAVSLVEAISSAIIDKTGWERKKVVTGILLVGFIISILFATRAGLYLLDIMDNFINNYGVVVVGLLE
TILVGWIVKPETIRDHTNSVSYYRIGKWWDIIIKCINPIVLTFILVQSFITEMRTPYGGYDLQALFVYGWGAILIGITGS
ILISKQPWRDNINLKNE

Sequences:

>Translated_497_residues
MKKSREQWGTKAGFLLAAIGSAVGLGNIWRFPYVAYSNGGGAFLIPYFFAIFTAGIPLLILEYGMGHKFRGSTPLAIARA
NKKWEWLGWWPIISAVIILSYYSMILSLAMKYLTLSFNKVWGNDTNSYFYDEVLKVSSSPFDFRGIIIPILIGITLVWLI
NWFICYKGIKAGIEKLSKILLPALLIIMIIIVIKGVTLKGASLGLNTLFTPDWKKVKDPKVWIAAYGQVFFSLSIATGIM
MTYSSYLPKKTDINNSAFMTAFANCGFEFLSAIGVFAILGFMATNQGVSIDKVASGGIGLAFIAFPKVFSVMGIWGNILS
VLFFTCLIFAGLTSAVSLVEAISSAIIDKTGWERKKVVTGILLVGFIISILFATRAGLYLLDIMDNFINNYGVVVVGLLE
TILVGWIVKPETIRDHTNSVSYYRIGKWWDIIIKCINPIVLTFILVQSFITEMRTPYGGYDLQALFVYGWGAILIGITGS
ILISKQPWRDNINLKNE
>Mature_497_residues
MKKSREQWGTKAGFLLAAIGSAVGLGNIWRFPYVAYSNGGGAFLIPYFFAIFTAGIPLLILEYGMGHKFRGSTPLAIARA
NKKWEWLGWWPIISAVIILSYYSMILSLAMKYLTLSFNKVWGNDTNSYFYDEVLKVSSSPFDFRGIIIPILIGITLVWLI
NWFICYKGIKAGIEKLSKILLPALLIIMIIIVIKGVTLKGASLGLNTLFTPDWKKVKDPKVWIAAYGQVFFSLSIATGIM
MTYSSYLPKKTDINNSAFMTAFANCGFEFLSAIGVFAILGFMATNQGVSIDKVASGGIGLAFIAFPKVFSVMGIWGNILS
VLFFTCLIFAGLTSAVSLVEAISSAIIDKTGWERKKVVTGILLVGFIISILFATRAGLYLLDIMDNFINNYGVVVVGLLE
TILVGWIVKPETIRDHTNSVSYYRIGKWWDIIIKCINPIVLTFILVQSFITEMRTPYGGYDLQALFVYGWGAILIGITGS
ILISKQPWRDNINLKNE

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=489, Percent_Identity=28.8343558282209, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI289191351, Length=499, Percent_Identity=29.6593186372746, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI4557046, Length=499, Percent_Identity=29.6593186372746, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI7657587, Length=488, Percent_Identity=29.7131147540984, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI289191377, Length=499, Percent_Identity=29.6593186372746, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI171184408, Length=463, Percent_Identity=31.9654427645788, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI171184406, Length=463, Percent_Identity=31.9654427645788, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI171184404, Length=463, Percent_Identity=31.9654427645788, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI92859670, Length=525, Percent_Identity=28.1904761904762, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI67782317, Length=508, Percent_Identity=29.1338582677165, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI67782313, Length=508, Percent_Identity=29.1338582677165, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI67782315, Length=508, Percent_Identity=29.1338582677165, Blast_Score=198, Evalue=9e-51,
Organism=Homo sapiens, GI4507043, Length=482, Percent_Identity=29.253112033195, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI4507041, Length=497, Percent_Identity=28.9738430583501, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI197276623, Length=489, Percent_Identity=29.038854805726, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI54607094, Length=489, Percent_Identity=29.038854805726, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI134304856, Length=498, Percent_Identity=28.1124497991968, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI6005715, Length=529, Percent_Identity=28.1663516068053, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI188528618, Length=488, Percent_Identity=26.2295081967213, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI194018524, Length=524, Percent_Identity=28.6259541984733, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI51468073, Length=531, Percent_Identity=26.3653483992467, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI58219014, Length=548, Percent_Identity=25.7299270072993, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI5032097, Length=490, Percent_Identity=28.1632653061224, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI11181770, Length=538, Percent_Identity=26.5799256505576, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI218563756, Length=490, Percent_Identity=27.9591836734694, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI300360519, Length=312, Percent_Identity=29.1666666666667, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI289191353, Length=314, Percent_Identity=28.9808917197452, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI33354281, Length=306, Percent_Identity=28.7581699346405, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI12408638, Length=523, Percent_Identity=23.9005736137667, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI218563758, Length=303, Percent_Identity=29.042904290429, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI197276625, Length=127, Percent_Identity=37.7952755905512, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI21361693, Length=119, Percent_Identity=33.6134453781513, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI55749589, Length=303, Percent_Identity=25.0825082508251, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI226437581, Length=252, Percent_Identity=25.3968253968254, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555248, Length=509, Percent_Identity=28.8801571709234, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71995588, Length=512, Percent_Identity=26.7578125, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17554804, Length=474, Percent_Identity=29.746835443038, Blast_Score=181, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI17535731, Length=555, Percent_Identity=26.6666666666667, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI133952791, Length=548, Percent_Identity=27.1897810218978, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71998244, Length=394, Percent_Identity=29.4416243654822, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI25146584, Length=462, Percent_Identity=26.6233766233766, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17542050, Length=478, Percent_Identity=27.1966527196653, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17569475, Length=452, Percent_Identity=25.4424778761062, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI115534083, Length=552, Percent_Identity=21.9202898550725, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI212642127, Length=339, Percent_Identity=27.7286135693215, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25143236, Length=456, Percent_Identity=19.9561403508772, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI221329674, Length=497, Percent_Identity=31.1871227364185, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24639514, Length=498, Percent_Identity=31.1244979919679, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24762620, Length=484, Percent_Identity=31.6115702479339, Blast_Score=211, Evalue=6e-55,
Organism=Drosophila melanogaster, GI24654186, Length=529, Percent_Identity=27.7882797731569, Blast_Score=208, Evalue=8e-54,
Organism=Drosophila melanogaster, GI281364136, Length=520, Percent_Identity=29.6153846153846, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24639516, Length=518, Percent_Identity=29.9227799227799, Blast_Score=205, Evalue=6e-53,
Organism=Drosophila melanogaster, GI19921936, Length=528, Percent_Identity=27.6515151515151, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24661428, Length=505, Percent_Identity=27.1287128712871, Blast_Score=199, Evalue=5e-51,
Organism=Drosophila melanogaster, GI24655079, Length=539, Percent_Identity=30.4267161410019, Blast_Score=198, Evalue=7e-51,
Organism=Drosophila melanogaster, GI281365034, Length=501, Percent_Identity=29.3413173652695, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI281363702, Length=490, Percent_Identity=28.5714285714286, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24582567, Length=470, Percent_Identity=27.6595744680851, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24639853, Length=544, Percent_Identity=28.8602941176471, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI19921352, Length=507, Percent_Identity=28.2051282051282, Blast_Score=188, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24584353, Length=507, Percent_Identity=28.2051282051282, Blast_Score=188, Evalue=8e-48,
Organism=Drosophila melanogaster, GI17136952, Length=479, Percent_Identity=26.7223382045929, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI45551088, Length=523, Percent_Identity=26.1950286806883, Blast_Score=182, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24652942, Length=523, Percent_Identity=26.1950286806883, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI281364394, Length=479, Percent_Identity=26.7223382045929, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28574704, Length=479, Percent_Identity=26.7223382045929, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI17136950, Length=479, Percent_Identity=26.7223382045929, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28574702, Length=479, Percent_Identity=26.7223382045929, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI45550877, Length=496, Percent_Identity=25.4032258064516, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI281363700, Length=338, Percent_Identity=31.3609467455621, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI45551183, Length=398, Percent_Identity=27.3869346733668, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24582569, Length=440, Percent_Identity=25.9090909090909, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 55090; Mature: 55090

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSREQWGTKAGFLLAAIGSAVGLGNIWRFPYVAYSNGGGAFLIPYFFAIFTAGIPLLI
CCCCHHHHCCHHHHHHHHHHHHHCCCCHHCCCEEEEECCCCEEHHHHHHHHHHCCHHHHH
LEYGMGHKFRGSTPLAIARANKKWEWLGWWPIISAVIILSYYSMILSLAMKYLTLSFNKV
HHHCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGNDTNSYFYDEVLKVSSSPFDFRGIIIPILIGITLVWLINWFICYKGIKAGIEKLSKIL
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPALLIIMIIIVIKGVTLKGASLGLNTLFTPDWKKVKDPKVWIAAYGQVFFSLSIATGIM
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MTYSSYLPKKTDINNSAFMTAFANCGFEFLSAIGVFAILGFMATNQGVSIDKVASGGIGL
HHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHH
AFIAFPKVFSVMGIWGNILSVLFFTCLIFAGLTSAVSLVEAISSAIIDKTGWERKKVVTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ILLVGFIISILFATRAGLYLLDIMDNFINNYGVVVVGLLETILVGWIVKPETIRDHTNSV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCC
SYYRIGKWWDIIIKCINPIVLTFILVQSFITEMRTPYGGYDLQALFVYGWGAILIGITGS
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC
ILISKQPWRDNINLKNE
EEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKKSREQWGTKAGFLLAAIGSAVGLGNIWRFPYVAYSNGGGAFLIPYFFAIFTAGIPLLI
CCCCHHHHCCHHHHHHHHHHHHHCCCCHHCCCEEEEECCCCEEHHHHHHHHHHCCHHHHH
LEYGMGHKFRGSTPLAIARANKKWEWLGWWPIISAVIILSYYSMILSLAMKYLTLSFNKV
HHHCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGNDTNSYFYDEVLKVSSSPFDFRGIIIPILIGITLVWLINWFICYKGIKAGIEKLSKIL
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPALLIIMIIIVIKGVTLKGASLGLNTLFTPDWKKVKDPKVWIAAYGQVFFSLSIATGIM
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MTYSSYLPKKTDINNSAFMTAFANCGFEFLSAIGVFAILGFMATNQGVSIDKVASGGIGL
HHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHH
AFIAFPKVFSVMGIWGNILSVLFFTCLIFAGLTSAVSLVEAISSAIIDKTGWERKKVVTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ILLVGFIISILFATRAGLYLLDIMDNFINNYGVVVVGLLETILVGWIVKPETIRDHTNSV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCC
SYYRIGKWWDIIIKCINPIVLTFILVQSFITEMRTPYGGYDLQALFVYGWGAILIGITGS
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC
ILISKQPWRDNINLKNE
EEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]