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The map label for this gene is xerC [H]

Identifier: 153936224

GI number: 153936224

Start: 1838087

End: 1839067

Strand: Direct

Name: xerC [H]

Synonym: CLC_1735

Alternate gene names: 153936224

Gene position: 1838087-1839067 (Clockwise)

Preceding gene: 153936948

Following gene: 153936246

Centisome position: 48.88

GC content: 26.91

Gene sequence:

>981_bases
ATGAAATATAATATTCAACAATTATATGATGCTAATTTTCCCCAAAGATTAAATGATTTTTTAAATTATCTTAGAACTAT
AAAAGGAAAATCAGAAAATACAATTGAAAGCTACAAATTAGATTTGATTATGTTTTTTAGATTTTTAAAATTATACAAAG
GTATGGTTCCTGGAGAGACAGAATTTAATGATATAGAAATAAAGGATATAAGTGATGAAGACATTAAGAATATATCATTA
ACAGATTTGTTTGCTTTTGTATCCTTTGTAGAGAATTATAGAAATAACGGTAGCTATGCTAAAGCTAGAAAAGTAGCTAC
ACTAAAATCTTTCTTTAGATTTTTGCAGGGTAAAGTTAAAATTATAAAGGAGAACCCTGCTCTAGAATTAGAAAGCCCTA
AAATAAGTAAAAGAAATCCTGTATATTTAACATTAGATGAGAGTAAAAGGCTATTATCTTCTATAGATGGTAAGTTTAAA
GAAAGAGATCTATGCATAGTGACTATGTTCTTAAATTGTGGATTGAGACTTTCAGAATTATGTGGTATAAACATATCTAA
TATTAAAAATGATATTTTAACCGTTGTAGGTAAAGGAAACAAAGAAAGAACTGTATACCTTAATAAAGCTTGCATTAAAA
CTTTAAATGATTATTTAAATGTAAGAAAAGAAATGGGAGAAAAAATAGTGGATAAAGATGCTCTATTTTTAAGTAAAAAT
TATACAAGGATAAATAAACGTTCTGTAGAGATGTTAGTAAAGAAGTATGTAAAAAAAGCAGGTTTAGATGGAGAAAAATA
TTCTCCTCATAAATTGAGACATACAGCAGCTACATTGATGTACAAGCATGGTGGCGTTGATATAAGAAGTTTACAAATGA
TATTAGGCCATGAAAATATATCTACAACCCAAATTTACACTCATGTAGACAGTGATAGATTAAGAGAAGCAGTTAAATCT
AATCCTTTAAGTGATGAATAA

Upstream 100 bases:

>100_bases
AAAGAAGGATTTTCCCCCTTTTATATAGAATATTATAATCGCGAAATATAAATTTCGCGAAGTTGTTGCTATTTTTAGGT
TAAGGAGGTACATATTTTCA

Downstream 100 bases:

>100_bases
GGCAAACTTTTTATTAGTGGCCAAAATTAATTTTTTATATAAAAATTAATACTTTGTTTATTTGAATGTATTTAAACTAC
AACTTAAATGAAAATGAATA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKYNIQQLYDANFPQRLNDFLNYLRTIKGKSENTIESYKLDLIMFFRFLKLYKGMVPGETEFNDIEIKDISDEDIKNISL
TDLFAFVSFVENYRNNGSYAKARKVATLKSFFRFLQGKVKIIKENPALELESPKISKRNPVYLTLDESKRLLSSIDGKFK
ERDLCIVTMFLNCGLRLSELCGINISNIKNDILTVVGKGNKERTVYLNKACIKTLNDYLNVRKEMGEKIVDKDALFLSKN
YTRINKRSVEMLVKKYVKKAGLDGEKYSPHKLRHTAATLMYKHGGVDIRSLQMILGHENISTTQIYTHVDSDRLREAVKS
NPLSDE

Sequences:

>Translated_326_residues
MKYNIQQLYDANFPQRLNDFLNYLRTIKGKSENTIESYKLDLIMFFRFLKLYKGMVPGETEFNDIEIKDISDEDIKNISL
TDLFAFVSFVENYRNNGSYAKARKVATLKSFFRFLQGKVKIIKENPALELESPKISKRNPVYLTLDESKRLLSSIDGKFK
ERDLCIVTMFLNCGLRLSELCGINISNIKNDILTVVGKGNKERTVYLNKACIKTLNDYLNVRKEMGEKIVDKDALFLSKN
YTRINKRSVEMLVKKYVKKAGLDGEKYSPHKLRHTAATLMYKHGGVDIRSLQMILGHENISTTQIYTHVDSDRLREAVKS
NPLSDE
>Mature_326_residues
MKYNIQQLYDANFPQRLNDFLNYLRTIKGKSENTIESYKLDLIMFFRFLKLYKGMVPGETEFNDIEIKDISDEDIKNISL
TDLFAFVSFVENYRNNGSYAKARKVATLKSFFRFLQGKVKIIKENPALELESPKISKRNPVYLTLDESKRLLSSIDGKFK
ERDLCIVTMFLNCGLRLSELCGINISNIKNDILTVVGKGNKERTVYLNKACIKTLNDYLNVRKEMGEKIVDKDALFLSKN
YTRINKRSVEMLVKKYVKKAGLDGEKYSPHKLRHTAATLMYKHGGVDIRSLQMILGHENISTTQIYTHVDSDRLREAVKS
NPLSDE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=308, Percent_Identity=33.4415584415584, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1790244, Length=221, Percent_Identity=36.6515837104072, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 37675; Mature: 37675

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYNIQQLYDANFPQRLNDFLNYLRTIKGKSENTIESYKLDLIMFFRFLKLYKGMVPGET
CCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
EFNDIEIKDISDEDIKNISLTDLFAFVSFVENYRNNGSYAKARKVATLKSFFRFLQGKVK
CCCCEEEEECCCCHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEE
IIKENPALELESPKISKRNPVYLTLDESKRLLSSIDGKFKERDLCIVTMFLNCGLRLSEL
EEECCCCEEECCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCHHEEEEHHHCCCCHHHH
CGINISNIKNDILTVVGKGNKERTVYLNKACIKTLNDYLNVRKEMGEKIVDKDALFLSKN
HCCCHHHHHHHHEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECC
YTRINKRSVEMLVKKYVKKAGLDGEKYSPHKLRHTAATLMYKHGGVDIRSLQMILGHENI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
STTQIYTHVDSDRLREAVKSNPLSDE
CCEEEEEECCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKYNIQQLYDANFPQRLNDFLNYLRTIKGKSENTIESYKLDLIMFFRFLKLYKGMVPGET
CCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
EFNDIEIKDISDEDIKNISLTDLFAFVSFVENYRNNGSYAKARKVATLKSFFRFLQGKVK
CCCCEEEEECCCCHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEE
IIKENPALELESPKISKRNPVYLTLDESKRLLSSIDGKFKERDLCIVTMFLNCGLRLSEL
EEECCCCEEECCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCHHEEEEHHHCCCCHHHH
CGINISNIKNDILTVVGKGNKERTVYLNKACIKTLNDYLNVRKEMGEKIVDKDALFLSKN
HCCCHHHHHHHHEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECC
YTRINKRSVEMLVKKYVKKAGLDGEKYSPHKLRHTAATLMYKHGGVDIRSLQMILGHENI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
STTQIYTHVDSDRLREAVKSNPLSDE
CCEEEEEECCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]