Click here to switch to the map view.

The map label for this gene is gltS [H]

Identifier: 153935957

GI number: 153935957

Start: 735110

End: 736294

Strand: Direct

Name: gltS [H]

Synonym: CLC_0715

Alternate gene names: 153935957

Gene position: 735110-736294 (Clockwise)

Preceding gene: 153937277

Following gene: 153936774

Centisome position: 19.55

GC content: 32.91

Gene sequence:

>1185_bases
ATGACACTAGAGCTTGATATGATTCAAACCACTACCTTAGCTATACTTTTCTATTATATAGGTATATTTATAAAATCTAA
AGTTTCAATTCTTGAAAAATTTTGTATACCTGCTCCAGTTGTAGGTGGACTTATTTTTGCTATTTTAAATTTAATCTTTA
CAGAAAGTGGTTTTATATCTATATCTTTAGACACAACTCTTCAAAAGCCTTTTATGTTAGCTTTCTTTACAACTATTGGC
TTTGGGGCAAGTTTTAAGATGATAAAACAGGGTGGTCTTCATGTGATAATGTTTTTTATAGCGGCTCTTCTTTTAGTAAT
ATCACAAGACGTTCTTGGAGTAGTTATGGCTAAATTTATAGGTGAAGATCCACTTCTTGGATTAATTGTTGGGTCCGTAA
CCATGACTGGTGGTCATGGAACAGGAGCCACTTTTGGAGCCTTATTCGAATCAGAATACGGCCTTGTAGGCGCTTCCACT
ACAGCTATGGCTGCCGCTACCTTTGGGCTTGTATGTGGTAGCTTAATAGGTGGTCCGATAGCTAAAAACCTAATAAGTAA
AAATAACCTAAAAAATAGCTCAGATGAGTTTTTTGAAGCAAATTCTGATGATTGTGAAGAAGTGAGTTATAAAACGCTAT
TTAATACATTTTCTCTTATATTTATATCAATGGGACTCGGTTCTATTTTAGAGATGCTTTTTACAAATCTTGGTATAGTC
CTTCCTTCATACGTAGATGCTATGATAGTGGCAGCTATAATACTTAATATAGGGGAACAAACAAATAAATGGAAAATAAA
TTCAAAATGTGTTGATATAATTGGAAATATGAGCCTTAATGTGTTTTTATCCATGGCACTCATAGGTCTTAAATTATGGG
AATTAAAAAGCACAGCAGGTCCATTATTAATTTTATTAATAGGCCAAGCTGTATTAATGTTTATATTTGCATACTTTATT
ACTTTTAGACTAATGGGAAAGGATTATGATGCTGCTGTTATGAGTTCTGGGCATTGTGGATTTGGAATGGGAGCTACTCC
TAACGGTATAGCAAACATGGAAGCCATAACTTCTAAATATGGTGCATCACCAAAAGCATTTTTTATTCTTCCAGTTGTCG
GGGCATTTTTAATAGACTTTTCTAATTCTTTAGTTATAACATTATTCGTAAATTTATTTAAATAA

Upstream 100 bases:

>100_bases
AATATATATTTGAATTTTCATATTTATGAATATTTTTTTTATTTCTATCATAAGTGATCATATAAACATAATATTGATTA
CATTATAAGGGGGATTTTTT

Downstream 100 bases:

>100_bases
TCCAATAAAAAATATAGCTAAGTAATATATAAATTAACCTGTTGTGCTAAGAGATAAGTTTTCATTAACAGGATTAATAT
ACCATATCACATAGGCACTG

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MTLELDMIQTTTLAILFYYIGIFIKSKVSILEKFCIPAPVVGGLIFAILNLIFTESGFISISLDTTLQKPFMLAFFTTIG
FGASFKMIKQGGLHVIMFFIAALLLVISQDVLGVVMAKFIGEDPLLGLIVGSVTMTGGHGTGATFGALFESEYGLVGAST
TAMAAATFGLVCGSLIGGPIAKNLISKNNLKNSSDEFFEANSDDCEEVSYKTLFNTFSLIFISMGLGSILEMLFTNLGIV
LPSYVDAMIVAAIILNIGEQTNKWKINSKCVDIIGNMSLNVFLSMALIGLKLWELKSTAGPLLILLIGQAVLMFIFAYFI
TFRLMGKDYDAAVMSSGHCGFGMGATPNGIANMEAITSKYGASPKAFFILPVVGAFLIDFSNSLVITLFVNLFK

Sequences:

>Translated_394_residues
MTLELDMIQTTTLAILFYYIGIFIKSKVSILEKFCIPAPVVGGLIFAILNLIFTESGFISISLDTTLQKPFMLAFFTTIG
FGASFKMIKQGGLHVIMFFIAALLLVISQDVLGVVMAKFIGEDPLLGLIVGSVTMTGGHGTGATFGALFESEYGLVGAST
TAMAAATFGLVCGSLIGGPIAKNLISKNNLKNSSDEFFEANSDDCEEVSYKTLFNTFSLIFISMGLGSILEMLFTNLGIV
LPSYVDAMIVAAIILNIGEQTNKWKINSKCVDIIGNMSLNVFLSMALIGLKLWELKSTAGPLLILLIGQAVLMFIFAYFI
TFRLMGKDYDAAVMSSGHCGFGMGATPNGIANMEAITSKYGASPKAFFILPVVGAFLIDFSNSLVITLFVNLFK
>Mature_393_residues
TLELDMIQTTTLAILFYYIGIFIKSKVSILEKFCIPAPVVGGLIFAILNLIFTESGFISISLDTTLQKPFMLAFFTTIGF
GASFKMIKQGGLHVIMFFIAALLLVISQDVLGVVMAKFIGEDPLLGLIVGSVTMTGGHGTGATFGALFESEYGLVGASTT
AMAAATFGLVCGSLIGGPIAKNLISKNNLKNSSDEFFEANSDDCEEVSYKTLFNTFSLIFISMGLGSILEMLFTNLGIVL
PSYVDAMIVAAIILNIGEQTNKWKINSKCVDIIGNMSLNVFLSMALIGLKLWELKSTAGPLLILLIGQAVLMFIFAYFIT
FRLMGKDYDAAVMSSGHCGFGMGATPNGIANMEAITSKYGASPKAFFILPVVGAFLIDFSNSLVITLFVNLFK

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=372, Percent_Identity=43.2795698924731, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 42267; Mature: 42136

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLELDMIQTTTLAILFYYIGIFIKSKVSILEKFCIPAPVVGGLIFAILNLIFTESGFIS
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEE
ISLDTTLQKPFMLAFFTTIGFGASFKMIKQGGLHVIMFFIAALLLVISQDVLGVVMAKFI
EEECCHHCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEDPLLGLIVGSVTMTGGHGTGATFGALFESEYGLVGASTTAMAAATFGLVCGSLIGGPI
CCCCHHHHEEHHEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHH
AKNLISKNNLKNSSDEFFEANSDDCEEVSYKTLFNTFSLIFISMGLGSILEMLFTNLGIV
HHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPSYVDAMIVAAIILNIGEQTNKWKINSKCVDIIGNMSLNVFLSMALIGLKLWELKSTAG
HHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
PLLILLIGQAVLMFIFAYFITFRLMGKDYDAAVMSSGHCGFGMGATPNGIANMEAITSKY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
GASPKAFFILPVVGAFLIDFSNSLVITLFVNLFK
CCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHC
>Mature Secondary Structure 
TLELDMIQTTTLAILFYYIGIFIKSKVSILEKFCIPAPVVGGLIFAILNLIFTESGFIS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEE
ISLDTTLQKPFMLAFFTTIGFGASFKMIKQGGLHVIMFFIAALLLVISQDVLGVVMAKFI
EEECCHHCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEDPLLGLIVGSVTMTGGHGTGATFGALFESEYGLVGASTTAMAAATFGLVCGSLIGGPI
CCCCHHHHEEHHEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHH
AKNLISKNNLKNSSDEFFEANSDDCEEVSYKTLFNTFSLIFISMGLGSILEMLFTNLGIV
HHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPSYVDAMIVAAIILNIGEQTNKWKINSKCVDIIGNMSLNVFLSMALIGLKLWELKSTAG
HHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
PLLILLIGQAVLMFIFAYFITFRLMGKDYDAAVMSSGHCGFGMGATPNGIANMEAITSKY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
GASPKAFFILPVVGAFLIDFSNSLVITLFVNLFK
CCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]