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The map label for this gene is resE [H]

Identifier: 153935782

GI number: 153935782

Start: 304973

End: 306391

Strand: Direct

Name: resE [H]

Synonym: CLC_0324

Alternate gene names: 153935782

Gene position: 304973-306391 (Clockwise)

Preceding gene: 153935185

Following gene: 153937334

Centisome position: 8.11

GC content: 27.48

Gene sequence:

>1419_bases
GTGGTATGGGATATAGGTTCAATGTTTAATAAATTAAGATATAGAGTAAGCTTGATTTTTATATTATTTTCATTGAGTAT
CATATTTTTAGCAAACATAGTAAACCATTATTGTATCGAAAAGAAGTTTAATATATATACTAGCGAAAAAATACAACAGT
CGAAAATGGAAATCAAAAATAAAATATCAAATGCATACAGTAATAATTCATGGGATAAAAAAGCTATTGAGAACATAGGA
ACAGATGCGATAACTGGAGGATTGCTTATAACAGTTAAAGATAAAAATGATAATATTATATGGAATGCAAGGGAATATGA
TAATATTGTATGTGAAAAGATTTTAAATAAAATTATAGAAAATACTAATAAAGTAAGCCCAGATGTAGATATTAAAAATA
CATTTGATAAATTTAACCTAAAACAAGGTGAAGCTTTAATAGGAAAATTAGAAATTGAGTATATAGGTCCAATTTATTAT
GAAGATTCAGATGTTATATTTTTGAGAATGCTAGATAGAATATTATTTATACTAGGGCTACTATTTTTTATTATATCTAT
TATAGTAGGATGGTTATTGTCTTATGCTATCAGTAAACCTATCTTAAAGGTAATAGATGCAACAAATCTTATATCAGAAG
GAAATTATTCCAAAGGCATAAAAGAAGATTACAGTATATATGAAATCAATAAACTTATAAAATCAATAAATATGATGGCA
GGAGATTTAGATAAGCAAGAAAAAATAAGACAAGAGTTAACGAAGGATATATCACATGAGCTTAGAACCCCTATAACGAC
TATGCAAGCACAACTTGAGGCAATAATGGATGGTCTATGGGAGCCATCCCAAGAAAGGTTAAAGAGTATATATGATGAAC
TTCAAAGATTAAATAGATTAACTGTATCCATAGAGGATTTATCAAGATGTGAGGGCAGTAAACTAAGGTTAAATAAGTCA
GAAGTAGATTTAGAGACTGTAATAACTACAATTTTAACAAATTTTGAAAAGCAGTTATTAGATAAAGATATAAATTTACA
AGTAGATCTTAAACATATTAATATTATGATAGATAGGGATAAAATAAGCCAGGTAATACTTAATATTATCTCAAATGCTA
TTAAGTATACTCCAGATAAAGGAGAGATATTTGTTAGGTGTTTTATTAAATCTGATAATGTATATATATCTATAAAAGAT
AGCGGAATAGGTATAAGTGATGAAGATAAAGACTATATATTTGAGAGATTTTATAGAACGGATAAGTCAAGGGCTAGAGA
AACCGGAGGAGTTGGGATAGGACTTACAATATCAAGAGAAATAGTCAAGGCTCATGGTGGCAGTATAAATGTATATAGTA
AATTAGATGAAGGTAGCAACTTCGTAATAAAACTGCCAATAAAATTTTGTGGGACATAA

Upstream 100 bases:

>100_bases
AATACTTGTATCTATGATAGAATAATTGATACTCATATAAAAAATATAAGAGCCAAATTAGATCAAGATAGTAAAAATCC
AACCTATATAAAGACTATTC

Downstream 100 bases:

>100_bases
TATTTGAACTTAATTTTTATATCAATCTAGAAGACACTCTTACTTTTGGTAGGCATGAGTGTCTTTTAAACTTACAATTT
TATAAAAATTAAGATATTAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MVWDIGSMFNKLRYRVSLIFILFSLSIIFLANIVNHYCIEKKFNIYTSEKIQQSKMEIKNKISNAYSNNSWDKKAIENIG
TDAITGGLLITVKDKNDNIIWNAREYDNIVCEKILNKIIENTNKVSPDVDIKNTFDKFNLKQGEALIGKLEIEYIGPIYY
EDSDVIFLRMLDRILFILGLLFFIISIIVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKSINMMA
GDLDKQEKIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQRLNRLTVSIEDLSRCEGSKLRLNKS
EVDLETVITTILTNFEKQLLDKDINLQVDLKHINIMIDRDKISQVILNIISNAIKYTPDKGEIFVRCFIKSDNVYISIKD
SGIGISDEDKDYIFERFYRTDKSRARETGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT

Sequences:

>Translated_472_residues
MVWDIGSMFNKLRYRVSLIFILFSLSIIFLANIVNHYCIEKKFNIYTSEKIQQSKMEIKNKISNAYSNNSWDKKAIENIG
TDAITGGLLITVKDKNDNIIWNAREYDNIVCEKILNKIIENTNKVSPDVDIKNTFDKFNLKQGEALIGKLEIEYIGPIYY
EDSDVIFLRMLDRILFILGLLFFIISIIVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKSINMMA
GDLDKQEKIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQRLNRLTVSIEDLSRCEGSKLRLNKS
EVDLETVITTILTNFEKQLLDKDINLQVDLKHINIMIDRDKISQVILNIISNAIKYTPDKGEIFVRCFIKSDNVYISIKD
SGIGISDEDKDYIFERFYRTDKSRARETGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT
>Mature_472_residues
MVWDIGSMFNKLRYRVSLIFILFSLSIIFLANIVNHYCIEKKFNIYTSEKIQQSKMEIKNKISNAYSNNSWDKKAIENIG
TDAITGGLLITVKDKNDNIIWNAREYDNIVCEKILNKIIENTNKVSPDVDIKNTFDKFNLKQGEALIGKLEIEYIGPIYY
EDSDVIFLRMLDRILFILGLLFFIISIIVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKSINMMA
GDLDKQEKIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQRLNRLTVSIEDLSRCEGSKLRLNKS
EVDLETVITTILTNFEKQLLDKDINLQVDLKHINIMIDRDKISQVILNIISNAIKYTPDKGEIFVRCFIKSDNVYISIKD
SGIGISDEDKDYIFERFYRTDKSRARETGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=270, Percent_Identity=31.4814814814815, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=29.3103448275862, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=29.045643153527, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790346, Length=271, Percent_Identity=29.8892988929889, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=30.2222222222222, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1789149, Length=330, Percent_Identity=25.7575757575758, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787894, Length=316, Percent_Identity=25.9493670886076, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082128, Length=293, Percent_Identity=26.6211604095563, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI48994928, Length=214, Percent_Identity=31.7757009345794, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788279, Length=295, Percent_Identity=26.4406779661017, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=27.9527559055118, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=27.9527559055118, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081816, Length=339, Percent_Identity=24.7787610619469, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=29.7297297297297, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=25.7261410788382, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790861, Length=308, Percent_Identity=24.6753246753247, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789808, Length=296, Percent_Identity=23.3108108108108, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787374, Length=278, Percent_Identity=23.3812949640288, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789403, Length=281, Percent_Identity=23.8434163701068, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790300, Length=242, Percent_Identity=26.0330578512397, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=21.5547703180212, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54190; Mature: 54190

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWDIGSMFNKLRYRVSLIFILFSLSIIFLANIVNHYCIEKKFNIYTSEKIQQSKMEIKN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KISNAYSNNSWDKKAIENIGTDAITGGLLITVKDKNDNIIWNAREYDNIVCEKILNKIIE
HHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHH
NTNKVSPDVDIKNTFDKFNLKQGEALIGKLEIEYIGPIYYEDSDVIFLRMLDRILFILGL
CCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEEEEECCEEECCCCCHHHHHHHHHHHHHHH
LFFIISIIVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKSINMMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GDLDKQEKIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQRLNRL
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TVSIEDLSRCEGSKLRLNKSEVDLETVITTILTNFEKQLLDKDINLQVDLKHINIMIDRD
EEEHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEHH
KISQVILNIISNAIKYTPDKGEIFVRCFIKSDNVYISIKDSGIGISDEDKDYIFERFYRT
HHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHC
DKSRARETGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT
CHHHHHHCCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHCCC
>Mature Secondary Structure
MVWDIGSMFNKLRYRVSLIFILFSLSIIFLANIVNHYCIEKKFNIYTSEKIQQSKMEIKN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KISNAYSNNSWDKKAIENIGTDAITGGLLITVKDKNDNIIWNAREYDNIVCEKILNKIIE
HHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHH
NTNKVSPDVDIKNTFDKFNLKQGEALIGKLEIEYIGPIYYEDSDVIFLRMLDRILFILGL
CCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEEEEECCEEECCCCCHHHHHHHHHHHHHHH
LFFIISIIVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKSINMMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GDLDKQEKIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQRLNRL
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TVSIEDLSRCEGSKLRLNKSEVDLETVITTILTNFEKQLLDKDINLQVDLKHINIMIDRD
EEEHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEHH
KISQVILNIISNAIKYTPDKGEIFVRCFIKSDNVYISIKDSGIGISDEDKDYIFERFYRT
HHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHC
DKSRARETGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT
CHHHHHHCCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]