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The map label for this gene is yabD [H]

Identifier: 153934841

GI number: 153934841

Start: 101941

End: 102735

Strand: Direct

Name: yabD [H]

Synonym: CLC_0125

Alternate gene names: 153934841

Gene position: 101941-102735 (Clockwise)

Preceding gene: 153937583

Following gene: 153935585

Centisome position: 2.71

GC content: 28.05

Gene sequence:

>795_bases
ATGAAAAAATATAGAATATTTGATGCTCATGCCCATTATGATGATGAAGCTTTTGATGAAGATAGAAGTGAAGTTATAAA
AGAACTTGAAGATTTTGGTATATTAGGAGTATTAAATTGTGGTTCTTCTTTAGATACTTCTAAAACATCAGTAGAATTGA
GCAACAAATATAATTTCTTTTATGCAGCAGTAGGCGTGCATCCAGAAAATGCAGAAGAAATTAATGAAAAAACCTTAAAT
AAAATAGAAGCACTATCAGAAAATAAAAAAGTAAAAGCTATAGGAGAAATAGGGCTAGATTATTATTATGAAGAAAATCC
TAAGCGGGATATTCAAATAAAAGCTTTTAAAAAGCAAATGGAATTAGCAGAAAAGTTAAACTTGCCTGTAGTTATACACG
ATAGAGATGCACATAAAGATACATTAGATATTATAAAACAATTTCCTAATATAAAAGGAGAAGTGCATTGTTTTTCAGGG
AGTGTAGAGTTTGCTAAGCAATGTGTAGATTTAGGATATTATATAGGGGTTACAGGAGTGGTCACTTTTAAAAATGCTAA
AAAAATAGTAGAAGTTATAAAAAGTGTTCCAATGGATAGAATCTTAGTTGAAACTGATTGCCCATATATGGCTCCTACTC
CTTTAAGAGGTAAAAGGAACAGATCTGAGTATATAAAATATATGGTAGATAAGATAGCAGAAATAAAAGAAATAAGTTCT
GAAGAAGTAACTTCACAAATACTAATTAATATAAAAGATCTATTTAATATAGATGTTATAAAAAATAAAGATTAA

Upstream 100 bases:

>100_bases
GAAAAATTTTAATTATAATATATAGAAAATGAAAAATTATTAAGAATATATTAATAAAGTTTAAAGAAAAAATAAAATAT
TGGGATTTGGAGGCAATTCT

Downstream 100 bases:

>100_bases
AAATATGAGAAATATTAATAATAATTTTGAATTTCTCATATATTTTAAATAAATTTATTTTGGAGTATTCCACCGATACC
CTTTATTTAAAAAGCAATTA

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKKYRIFDAHAHYDDEAFDEDRSEVIKELEDFGILGVLNCGSSLDTSKTSVELSNKYNFFYAAVGVHPENAEEINEKTLN
KIEALSENKKVKAIGEIGLDYYYEENPKRDIQIKAFKKQMELAEKLNLPVVIHDRDAHKDTLDIIKQFPNIKGEVHCFSG
SVEFAKQCVDLGYYIGVTGVVTFKNAKKIVEVIKSVPMDRILVETDCPYMAPTPLRGKRNRSEYIKYMVDKIAEIKEISS
EEVTSQILINIKDLFNIDVIKNKD

Sequences:

>Translated_264_residues
MKKYRIFDAHAHYDDEAFDEDRSEVIKELEDFGILGVLNCGSSLDTSKTSVELSNKYNFFYAAVGVHPENAEEINEKTLN
KIEALSENKKVKAIGEIGLDYYYEENPKRDIQIKAFKKQMELAEKLNLPVVIHDRDAHKDTLDIIKQFPNIKGEVHCFSG
SVEFAKQCVDLGYYIGVTGVVTFKNAKKIVEVIKSVPMDRILVETDCPYMAPTPLRGKRNRSEYIKYMVDKIAEIKEISS
EEVTSQILINIKDLFNIDVIKNKD
>Mature_264_residues
MKKYRIFDAHAHYDDEAFDEDRSEVIKELEDFGILGVLNCGSSLDTSKTSVELSNKYNFFYAAVGVHPENAEEINEKTLN
KIEALSENKKVKAIGEIGLDYYYEENPKRDIQIKAFKKQMELAEKLNLPVVIHDRDAHKDTLDIIKQFPNIKGEVHCFSG
SVEFAKQCVDLGYYIGVTGVVTFKNAKKIVEVIKSVPMDRILVETDCPYMAPTPLRGKRNRSEYIKYMVDKIAEIKEISS
EEVTSQILINIKDLFNIDVIKNKD

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=244, Percent_Identity=31.1475409836066, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI225903439, Length=194, Percent_Identity=35.0515463917526, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI225903424, Length=164, Percent_Identity=38.4146341463415, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI110349734, Length=262, Percent_Identity=28.2442748091603, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI110349730, Length=262, Percent_Identity=27.8625954198473, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=27.7777777777778, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI226061614, Length=254, Percent_Identity=25.1968503937008, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=26.8722466960352, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1787342, Length=261, Percent_Identity=32.5670498084291, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=30.8880308880309, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=31.1284046692607, Blast_Score=141, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17559024, Length=218, Percent_Identity=33.9449541284404, Blast_Score=133, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17565396, Length=224, Percent_Identity=32.1428571428571, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=241, Percent_Identity=31.5352697095436, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=24.5210727969349, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648690, Length=283, Percent_Identity=28.2685512367491, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI221330018, Length=241, Percent_Identity=30.2904564315353, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24586117, Length=241, Percent_Identity=30.2904564315353, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30197; Mature: 30197

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYRIFDAHAHYDDEAFDEDRSEVIKELEDFGILGVLNCGSSLDTSKTSVELSNKYNFF
CCCEEEEECCCCCCCHHCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCEEE
YAAVGVHPENAEEINEKTLNKIEALSENKKVKAIGEIGLDYYYEENPKRDIQIKAFKKQM
EEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCEEECCCCCCCCHHHHHHHHH
ELAEKLNLPVVIHDRDAHKDTLDIIKQFPNIKGEVHCFSGSVEFAKQCVDLGYYIGVTGV
HHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEE
VTFKNAKKIVEVIKSVPMDRILVETDCPYMAPTPLRGKRNRSEYIKYMVDKIAEIKEISS
EEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCH
EEVTSQILINIKDLFNIDVIKNKD
HHHHHHHHHHHHHHHEEEEEECCC
>Mature Secondary Structure
MKKYRIFDAHAHYDDEAFDEDRSEVIKELEDFGILGVLNCGSSLDTSKTSVELSNKYNFF
CCCEEEEECCCCCCCHHCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCEEE
YAAVGVHPENAEEINEKTLNKIEALSENKKVKAIGEIGLDYYYEENPKRDIQIKAFKKQM
EEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCEEECCCCCCCCHHHHHHHHH
ELAEKLNLPVVIHDRDAHKDTLDIIKQFPNIKGEVHCFSGSVEFAKQCVDLGYYIGVTGV
HHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEE
VTFKNAKKIVEVIKSVPMDRILVETDCPYMAPTPLRGKRNRSEYIKYMVDKIAEIKEISS
EEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCH
EEVTSQILINIKDLFNIDVIKNKD
HHHHHHHHHHHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]