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The map label for this gene is cobU [H]

Identifier: 153934642

GI number: 153934642

Start: 990320

End: 990877

Strand: Direct

Name: cobU [H]

Synonym: CLC_0964

Alternate gene names: 153934642

Gene position: 990320-990877 (Clockwise)

Preceding gene: 153936900

Following gene: 153934718

Centisome position: 26.33

GC content: 25.27

Gene sequence:

>558_bases
ATGAGTAATAAAAATAAAGTTGTATTAATAACTGGTGGTGTAAGAAGTGGTAAAAGTGAATTTGCAGAAAGTCTACTCCA
AAAAGAGAAAAGTGTTTTATACATAGCTACAGCAAAAATTACAGACAAGGAAATGGAACATAGAGTAGAAAAACATAAGG
AAAGAAGAAATAGTGAATGGAAAACCTACGAAGGATATAAGGATTTAGGAAAAATAATAAAATATCATAATGAGAAAAAT
ATTTTATTAGATTGTGTAACTATAATGACGACAAACTTAATGTTTCATAAAGAAATAGATTATGAAAATATTAAAGAGGA
AGAATTAGATGAAATTTTAGAGGGGATAAAAAAAGAATTTCATGATCTAATAATATCAGTAAAGGAAGAAAATAAAAACA
TAATATTAGTTACTAATGAAGTAGGTTATAGTATTGTTCCAGCCTATAAATTAGGCAGAATATTTAGAGATTTCCAAGGT
ATTATAAATAAATTTATAGCTTCTTTGAGTGATGAAGTTTATTTAGTAACCTGTGGAATACCTTTAAAAATAAAATAA

Upstream 100 bases:

>100_bases
AAAAATAATTGATAAATATAATCAATAATTTCTCAAATAAGATAAAAATTAAAAAAACGCTAAAATATTTTTTATATAGT
ATTAGAATGGAGAATTAAAT

Downstream 100 bases:

>100_bases
ATTTTAATAACTAATTAATCTAATTATAAGTAAAAGAATTTTCCAATCGCATTTAATTTTAAAATCTATTCTAGGCATTG
AAATATAAGACTTAAGATAA

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSNKNKVVLITGGVRSGKSEFAESLLQKEKSVLYIATAKITDKEMEHRVEKHKERRNSEWKTYEGYKDLGKIIKYHNEKN
ILLDCVTIMTTNLMFHKEIDYENIKEEELDEILEGIKKEFHDLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQG
IINKFIASLSDEVYLVTCGIPLKIK

Sequences:

>Translated_185_residues
MSNKNKVVLITGGVRSGKSEFAESLLQKEKSVLYIATAKITDKEMEHRVEKHKERRNSEWKTYEGYKDLGKIIKYHNEKN
ILLDCVTIMTTNLMFHKEIDYENIKEEELDEILEGIKKEFHDLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQG
IINKFIASLSDEVYLVTCGIPLKIK
>Mature_184_residues
SNKNKVVLITGGVRSGKSEFAESLLQKEKSVLYIATAKITDKEMEHRVEKHKERRNSEWKTYEGYKDLGKIIKYHNEKNI
LLDCVTIMTTNLMFHKEIDYENIKEEELDEILEGIKKEFHDLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQGI
INKFIASLSDEVYLVTCGIPLKIK

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=184, Percent_Identity=42.3913043478261, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21486; Mature: 21355

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKNKVVLITGGVRSGKSEFAESLLQKEKSVLYIATAKITDKEMEHRVEKHKERRNSEW
CCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCC
KTYEGYKDLGKIIKYHNEKNILLDCVTIMTTNLMFHKEIDYENIKEEELDEILEGIKKEF
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHH
HDLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQGIINKFIASLSDEVYLVTCGI
HHHHEEEEECCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
PLKIK
EEEEC
>Mature Secondary Structure 
SNKNKVVLITGGVRSGKSEFAESLLQKEKSVLYIATAKITDKEMEHRVEKHKERRNSEW
CCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCC
KTYEGYKDLGKIIKYHNEKNILLDCVTIMTTNLMFHKEIDYENIKEEELDEILEGIKKEF
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHH
HDLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQGIINKFIASLSDEVYLVTCGI
HHHHEEEEECCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
PLKIK
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]