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The map label for this gene is galE [H]

Identifier: 152977625

GI number: 152977625

Start: 4024854

End: 4025873

Strand: Reverse

Name: galE [H]

Synonym: Bcer98_3965

Alternate gene names: 152977625

Gene position: 4025873-4024854 (Counterclockwise)

Preceding gene: 152977626

Following gene: 152977623

Centisome position: 98.5

GC content: 39.02

Gene sequence:

>1020_bases
ATGGCAATACTTGTAACGGGTGGAGCAGGATATATTGGTAGTCACACATGTGTAGAGTTGTTAAATAGCGGTTATGAAAT
TATCGTAGTAGATAATCTTTCTAATAGCTCAGAAGAAGCAATCAATCGTGTGAAGGAGATAACAGGTAGATCGTTTCCAT
TTTATAAAGAAGACGTTTTAAATCGTGAAGCACTTCATGCAATTTTTGAAGAAAATACGATTGAAGCGGTGATTCATTTT
GCTGGCTTAAAAGCAGTGGGAGAATCGGTTGAAATTCCGCTTACGTATTATCATAATAATATTACAAGCACATTAGTGTT
ATGTGAAGTGATGGAAAAGCATAATGTGAAAAAGATGATCTTCAGCTCATCTGCAACAGTATACGGTATTCCAGAGACAT
CACCAATTACAGAAGACTTCCCGTTAAGTGCAACCAATCCATACGGTCAAACGAAATTAATGATTGAACAAATTTTACGC
GATGTCGTTGTGGCAGATCCAGAATGGAGCGTAGTATTACTTCGATACTTCAACCCATTTGGTGCTCATGAAAGCGGGCG
CATTGGAGAAGACCCAAATGGTATTCCGAACAACTTAATGCCGTATGTAACACAGGTAGCAGTTGGGAAATTAAAAGAAT
TAAGTGTATTCGGAAATGATTATCCAACAAAAGATGGCACAGGTGTACGTGATTACATTCATGTTGTGGACCTAGCAAAT
GGCCATGTGAAGGCTCTTGAAAAGGTGCTCAAGACAACAGGAATAGATGCCTATAACCTTGGAACAGGAACGGGTTATAG
TGTATTAGAAATGGTGAAAGCTTTTGAGAAAGTTTCCGGAAGAAAGGTACCTTATAAAATTACAGAGCGCCGTCCTGGAG
ATGTGGCAATATGTTATGCAGATGCATCGAAAGCAAAAAGAGAACTAGGATGGGAAGCAAAACGTGGACTCGAGGAAATG
TGTGCGGATTCTTGGAGATGGCAAGTTAATAATAAAAATGGGTATCGAGAAGAGGAATAA

Upstream 100 bases:

>100_bases
TAAAATGTAAGATGGTGACTTGGGGGGATAAACATTTGGGGGAGGATATGTGGTATAATTTTAAAAGTTTATAATGAATG
AAATATGGAGGACTATACTT

Downstream 100 bases:

>100_bases
AAAACATACTAAGATTAGTAGCACAGACCATGACTATGGTCTGTGCTACTATTTTTTTATAGTAGAAGTGAGGAATAAAT
CGGAGGCAGCCTTTTTCGTT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MAILVTGGAGYIGSHTCVELLNSGYEIIVVDNLSNSSEEAINRVKEITGRSFPFYKEDVLNREALHAIFEENTIEAVIHF
AGLKAVGESVEIPLTYYHNNITSTLVLCEVMEKHNVKKMIFSSSATVYGIPETSPITEDFPLSATNPYGQTKLMIEQILR
DVVVADPEWSVVLLRYFNPFGAHESGRIGEDPNGIPNNLMPYVTQVAVGKLKELSVFGNDYPTKDGTGVRDYIHVVDLAN
GHVKALEKVLKTTGIDAYNLGTGTGYSVLEMVKAFEKVSGRKVPYKITERRPGDVAICYADASKAKRELGWEAKRGLEEM
CADSWRWQVNNKNGYREEE

Sequences:

>Translated_339_residues
MAILVTGGAGYIGSHTCVELLNSGYEIIVVDNLSNSSEEAINRVKEITGRSFPFYKEDVLNREALHAIFEENTIEAVIHF
AGLKAVGESVEIPLTYYHNNITSTLVLCEVMEKHNVKKMIFSSSATVYGIPETSPITEDFPLSATNPYGQTKLMIEQILR
DVVVADPEWSVVLLRYFNPFGAHESGRIGEDPNGIPNNLMPYVTQVAVGKLKELSVFGNDYPTKDGTGVRDYIHVVDLAN
GHVKALEKVLKTTGIDAYNLGTGTGYSVLEMVKAFEKVSGRKVPYKITERRPGDVAICYADASKAKRELGWEAKRGLEEM
CADSWRWQVNNKNGYREEE
>Mature_338_residues
AILVTGGAGYIGSHTCVELLNSGYEIIVVDNLSNSSEEAINRVKEITGRSFPFYKEDVLNREALHAIFEENTIEAVIHFA
GLKAVGESVEIPLTYYHNNITSTLVLCEVMEKHNVKKMIFSSSATVYGIPETSPITEDFPLSATNPYGQTKLMIEQILRD
VVVADPEWSVVLLRYFNPFGAHESGRIGEDPNGIPNNLMPYVTQVAVGKLKELSVFGNDYPTKDGTGVRDYIHVVDLANG
HVKALEKVLKTTGIDAYNLGTGTGYSVLEMVKAFEKVSGRKVPYKITERRPGDVAICYADASKAKRELGWEAKRGLEEMC
ADSWRWQVNNKNGYREEE

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=59.4117647058824, Blast_Score=424, Evalue=1e-119,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=59.4117647058824, Blast_Score=424, Evalue=1e-119,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=59.4117647058824, Blast_Score=424, Evalue=1e-119,
Organism=Homo sapiens, GI7657641, Length=349, Percent_Identity=24.0687679083095, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI42516563, Length=322, Percent_Identity=24.5341614906832, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1786974, Length=338, Percent_Identity=54.7337278106509, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI48994969, Length=360, Percent_Identity=25, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788353, Length=367, Percent_Identity=25.3405994550409, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=57.9710144927536, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=57.3487031700288, Blast_Score=405, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17568069, Length=338, Percent_Identity=28.4023668639053, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=53.6443148688047, Blast_Score=375, Evalue=1e-105,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=61.1111111111111, Blast_Score=441, Evalue=1e-124,
Organism=Drosophila melanogaster, GI21356223, Length=321, Percent_Identity=23.0529595015576, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37635; Mature: 37504

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVTGGAGYIGSHTCVELLNSGYEIIVVDNLSNSSEEAINRVKEITGRSFPFYKEDVL
CEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHH
NREALHAIFEENTIEAVIHFAGLKAVGESVEIPLTYYHNNITSTLVLCEVMEKHNVKKMI
CHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHCCHHHHH
FSSSATVYGIPETSPITEDFPLSATNPYGQTKLMIEQILRDVVVADPEWSVVLLRYFNPF
CCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
GAHESGRIGEDPNGIPNNLMPYVTQVAVGKLKELSVFGNDYPTKDGTGVRDYIHVVDLAN
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHCCC
GHVKALEKVLKTTGIDAYNLGTGTGYSVLEMVKAFEKVSGRKVPYKITERRPGDVAICYA
CHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEC
DASKAKRELGWEAKRGLEEMCADSWRWQVNNKNGYREEE
CHHHHHHHCCCHHHHCHHHHHCCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
AILVTGGAGYIGSHTCVELLNSGYEIIVVDNLSNSSEEAINRVKEITGRSFPFYKEDVL
EEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHH
NREALHAIFEENTIEAVIHFAGLKAVGESVEIPLTYYHNNITSTLVLCEVMEKHNVKKMI
CHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHCCHHHHH
FSSSATVYGIPETSPITEDFPLSATNPYGQTKLMIEQILRDVVVADPEWSVVLLRYFNPF
CCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
GAHESGRIGEDPNGIPNNLMPYVTQVAVGKLKELSVFGNDYPTKDGTGVRDYIHVVDLAN
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHCCC
GHVKALEKVLKTTGIDAYNLGTGTGYSVLEMVKAFEKVSGRKVPYKITERRPGDVAICYA
CHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEC
DASKAKRELGWEAKRGLEEMCADSWRWQVNNKNGYREEE
CHHHHHHHCCCHHHHCHHHHHCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]