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The map label for this gene is mmgA [H]

Identifier: 152977530

GI number: 152977530

Start: 3923406

End: 3924590

Strand: Reverse

Name: mmgA [H]

Synonym: Bcer98_3865

Alternate gene names: 152977530

Gene position: 3924590-3923406 (Counterclockwise)

Preceding gene: 152977531

Following gene: 152977529

Centisome position: 96.03

GC content: 46.41

Gene sequence:

>1185_bases
TTGGTAAGAACAGTTATTTTAAGTGCCGCAAGAACACCAGTTGGAAAATTTGGCGGAGTATTAAAAGATGTGAAAGCGTC
GAAGCTTGGAGGAATTGCCATTCAAGCTGCACTTGAGAGAGCAAATGTGAACAAAGACGATGTAGAAGAAGTGATATTCG
GGACGGTTCTGCAAGGAGGACAGGGGCAAATTCCTTCTCGCCAAGCAGCGAGGGAAGCCGGACTTCCTTGGGAGACGCGT
ACGGAAACAATAAATAAAGTTTGTGCATCAGGTCTTAGAGCTGTGACATTAGCGGATCAAATTATTCGCGCAGGGGATCA
AACGTTAATTGTAGCGGGCGGAATGGAGTCCATGAGCAACAGTCCGTACATTTTAGAAGGTGCGCGTTGGGGATATCGAA
TGGGACATAGTCAAGTTGTGGATTTAAATATAGTAGATGGCTTAACATGTTCATTCTCTGGCATCCATATGGGCGTATAC
GGTGGTGAGGTAGCGAAGGAAGAAGGAATTTCTCGCGAAGCACAAGATGAGTGGGCGTATCGCAGTCATCAACGTGCAAT
TATGGCACAGAAAGAAGGGAGATTTGACGAGGAAATCGTACCTGTAGCTGTACCGCAGCGCAAAGGTGATCCGATCGTTG
TGGCGAAGGACGAGGCGCCACGTGCAGATACAACAATCGAAAAATTAGCTACATTAAAGCCTGTTTTTGATAAGACAGCG
GCAGTAACAGCTGGAAATGCACCGGGCCTTAATGATGGCGGGGCGGCGCTTGTATTAATGAGCGAAGACAGAGCGCGGCA
AGAAGGCAGAAAGCCAGTAGCGACAATTTTAGCGCATACCGCAATTGCTGTAGAAGCAAAGAATTTTCCGAGAACGCCAG
GTTATGCAATAAATGAACTGCTGAAGAAAACTGGAAAAACAGTGGATGATATTGATTTATTTGAGATCAATGAAGCCTTT
GCAGCAGTTGCAATTGCGAGTGCAAATATTGCCGGAATTGACCCTGAAAAGATTAATGTAAATGGTGGAGCAGTTGCGAT
GGGGCATCCGATTGGAGCGAGCGGAGCACGGATTATTGTTACCTTGATTCATGCGTTAAAGCAACGCGGCGGCGGAATTG
GAATCGCTTCGATTTGTAGCGGCGGTGGCCAAGGTGACGCAATTATGATTGAAGTTCATTCATAA

Upstream 100 bases:

>100_bases
AATTCATACAACTTTAGATAGAGGTGCAAATTGCACCTCTTCTCAACGCAAAGATATCGAGCGAGCGCTCGGCAGTCAAA
AAGAAATGGGGGAATTGAAG

Downstream 100 bases:

>100_bases
AAAGGGGGAGAAGAAATGAGTATACAAAAAATTGTGGTAATCGGTGCCGGACAAATGGGATCAGGTATTGCACAGGTGTG
TGCAACGGCTGGCTATGAAG

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MVRTVILSAARTPVGKFGGVLKDVKASKLGGIAIQAALERANVNKDDVEEVIFGTVLQGGQGQIPSRQAAREAGLPWETR
TETINKVCASGLRAVTLADQIIRAGDQTLIVAGGMESMSNSPYILEGARWGYRMGHSQVVDLNIVDGLTCSFSGIHMGVY
GGEVAKEEGISREAQDEWAYRSHQRAIMAQKEGRFDEEIVPVAVPQRKGDPIVVAKDEAPRADTTIEKLATLKPVFDKTA
AVTAGNAPGLNDGGAALVLMSEDRARQEGRKPVATILAHTAIAVEAKNFPRTPGYAINELLKKTGKTVDDIDLFEINEAF
AAVAIASANIAGIDPEKINVNGGAVAMGHPIGASGARIIVTLIHALKQRGGGIGIASICSGGGQGDAIMIEVHS

Sequences:

>Translated_394_residues
MVRTVILSAARTPVGKFGGVLKDVKASKLGGIAIQAALERANVNKDDVEEVIFGTVLQGGQGQIPSRQAAREAGLPWETR
TETINKVCASGLRAVTLADQIIRAGDQTLIVAGGMESMSNSPYILEGARWGYRMGHSQVVDLNIVDGLTCSFSGIHMGVY
GGEVAKEEGISREAQDEWAYRSHQRAIMAQKEGRFDEEIVPVAVPQRKGDPIVVAKDEAPRADTTIEKLATLKPVFDKTA
AVTAGNAPGLNDGGAALVLMSEDRARQEGRKPVATILAHTAIAVEAKNFPRTPGYAINELLKKTGKTVDDIDLFEINEAF
AAVAIASANIAGIDPEKINVNGGAVAMGHPIGASGARIIVTLIHALKQRGGGIGIASICSGGGQGDAIMIEVHS
>Mature_394_residues
MVRTVILSAARTPVGKFGGVLKDVKASKLGGIAIQAALERANVNKDDVEEVIFGTVLQGGQGQIPSRQAAREAGLPWETR
TETINKVCASGLRAVTLADQIIRAGDQTLIVAGGMESMSNSPYILEGARWGYRMGHSQVVDLNIVDGLTCSFSGIHMGVY
GGEVAKEEGISREAQDEWAYRSHQRAIMAQKEGRFDEEIVPVAVPQRKGDPIVVAKDEAPRADTTIEKLATLKPVFDKTA
AVTAGNAPGLNDGGAALVLMSEDRARQEGRKPVATILAHTAIAVEAKNFPRTPGYAINELLKKTGKTVDDIDLFEINEAF
AAVAIASANIAGIDPEKINVNGGAVAMGHPIGASGARIIVTLIHALKQRGGGIGIASICSGGGQGDAIMIEVHS

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI4557237, Length=388, Percent_Identity=47.9381443298969, Blast_Score=339, Evalue=3e-93,
Organism=Homo sapiens, GI148539872, Length=389, Percent_Identity=46.7866323907455, Blast_Score=328, Evalue=5e-90,
Organism=Homo sapiens, GI167614485, Length=391, Percent_Identity=38.3631713554987, Blast_Score=264, Evalue=9e-71,
Organism=Homo sapiens, GI4501853, Length=393, Percent_Identity=37.1501272264631, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI4504327, Length=430, Percent_Identity=32.093023255814, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI194353979, Length=246, Percent_Identity=32.520325203252, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1788554, Length=392, Percent_Identity=50, Blast_Score=344, Evalue=6e-96,
Organism=Escherichia coli, GI87082165, Length=391, Percent_Identity=45.0127877237852, Blast_Score=325, Evalue=2e-90,
Organism=Escherichia coli, GI1787663, Length=400, Percent_Identity=38, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI48994986, Length=399, Percent_Identity=36.0902255639098, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1788683, Length=410, Percent_Identity=30, Blast_Score=183, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI25147385, Length=386, Percent_Identity=41.4507772020725, Blast_Score=294, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI133906874, Length=387, Percent_Identity=42.1188630490956, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17535921, Length=392, Percent_Identity=39.5408163265306, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17551802, Length=428, Percent_Identity=32.9439252336449, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17535917, Length=396, Percent_Identity=33.0808080808081, Blast_Score=185, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6325229, Length=392, Percent_Identity=43.6224489795918, Blast_Score=314, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6322031, Length=397, Percent_Identity=35.7682619647355, Blast_Score=199, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24655093, Length=391, Percent_Identity=47.5703324808184, Blast_Score=346, Evalue=1e-95,
Organism=Drosophila melanogaster, GI24640423, Length=392, Percent_Identity=43.8775510204082, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI17648125, Length=388, Percent_Identity=38.4020618556701, Blast_Score=248, Evalue=7e-66,
Organism=Drosophila melanogaster, GI17137578, Length=426, Percent_Identity=30.2816901408451, Blast_Score=171, Evalue=9e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 41357; Mature: 41357

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRTVILSAARTPVGKFGGVLKDVKASKLGGIAIQAALERANVNKDDVEEVIFGTVLQGG
CCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
QGQIPSRQAAREAGLPWETRTETINKVCASGLRAVTLADQIIRAGDQTLIVAGGMESMSN
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHCCC
SPYILEGARWGYRMGHSQVVDLNIVDGLTCSFSGIHMGVYGGEVAKEEGISREAQDEWAY
CCEEEECCCCCEECCCCEEEEEEEECCCEEECCCEEEEECCCHHHHHHCCCCHHHHHHHH
RSHQRAIMAQKEGRFDEEIVPVAVPQRKGDPIVVAKDEAPRADTTIEKLATLKPVFDKTA
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
AVTAGNAPGLNDGGAALVLMSEDRARQEGRKPVATILAHTAIAVEAKNFPRTPGYAINEL
EEECCCCCCCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCCHHHHHH
LKKTGKTVDDIDLFEINEAFAAVAIASANIAGIDPEKINVNGGAVAMGHPIGASGARIIV
HHHHCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEECCCCCCCCHHHHH
TLIHALKQRGGGIGIASICSGGGQGDAIMIEVHS
HHHHHHHHCCCCEEHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure
MVRTVILSAARTPVGKFGGVLKDVKASKLGGIAIQAALERANVNKDDVEEVIFGTVLQGG
CCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
QGQIPSRQAAREAGLPWETRTETINKVCASGLRAVTLADQIIRAGDQTLIVAGGMESMSN
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHCCC
SPYILEGARWGYRMGHSQVVDLNIVDGLTCSFSGIHMGVYGGEVAKEEGISREAQDEWAY
CCEEEECCCCCEECCCCEEEEEEEECCCEEECCCEEEEECCCHHHHHHCCCCHHHHHHHH
RSHQRAIMAQKEGRFDEEIVPVAVPQRKGDPIVVAKDEAPRADTTIEKLATLKPVFDKTA
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
AVTAGNAPGLNDGGAALVLMSEDRARQEGRKPVATILAHTAIAVEAKNFPRTPGYAINEL
EEECCCCCCCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCCHHHHHH
LKKTGKTVDDIDLFEINEAFAAVAIASANIAGIDPEKINVNGGAVAMGHPIGASGARIIV
HHHHCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEECCCCCCCCHHHHH
TLIHALKQRGGGIGIASICSGGGQGDAIMIEVHS
HHHHHHHHCCCCEEHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]