Click here to switch to the map view.

The map label for this gene is mmgB [H]

Identifier: 152977529

GI number: 152977529

Start: 3922539

End: 3923390

Strand: Reverse

Name: mmgB [H]

Synonym: Bcer98_3864

Alternate gene names: 152977529

Gene position: 3923390-3922539 (Counterclockwise)

Preceding gene: 152977530

Following gene: 152977528

Centisome position: 96.0

GC content: 39.67

Gene sequence:

>852_bases
ATGAGTATACAAAAAATTGTGGTAATCGGTGCCGGACAAATGGGATCAGGTATTGCACAGGTGTGTGCAACGGCTGGCTA
TGAAGTGTTTATGCAAGATGTAAAGCAAGAGCAATTAGAGAGGGGATTCGGTGTAATAACGAGAAATTTAGCGCGCCAAG
TAGAAAAGGGACGTATGGATGAAGAGACGAAGGACGCAACATTACGCCGTCTTACAACTATACTTGAATTAGATTGTGTG
AAAGAAGCAGATCTTGTGATTGAAGCTGCTGTAGAAAAAATGGATATCAAAAAGAAAATTTTTGCAAATTTAGATGAAAT
TGCTCCGGAACATACCATTTTAGCGACAAATACTTCTTCATTGCCAATTACCGAAATAGCAGCAACAACAAATCGGCCAG
AGAAAGTGATTGGTATGCACTTTATGAATCCTGTACCAGTAATGAAATTAGTGGAGATTATTCGCGGACTTGCAACAGAT
GATGCCGTGTATAAAGCAATTGAAGATATTACAAAGAAAATTGGGAAAGTGCCCGTTGAAGTAAATGACTTCCCTGGTTT
TGTTTCGAATCGTATTTTATTACCGATGATTAATGAAGCAATTTATGCGCTATATGAAGGTGTCGCAACGAAAGAGGCGA
TTGATGAGGTCATGAAGCTTGGCATGAATCATCCAATGGGACCATTAACATTGGCAGATTTTATCGGCTTAGACACATGC
TTATACATTATGGAAGTATTGCATGAGGGCTTAGGAGATAGCAAATATCGTCCATGTCCGCTCTTGCGGAAATATGTAAA
TGCTGGCTGGCTCGGTCGAAAAACAGGTCGTGGTTTTTACGTATATGAGTAA

Upstream 100 bases:

>100_bases
GCAACGCGGCGGCGGAATTGGAATCGCTTCGATTTGTAGCGGCGGTGGCCAAGGTGACGCAATTATGATTGAAGTTCATT
CATAAAAAGGGGGAGAAGAA

Downstream 100 bases:

>100_bases
AGGGGAAGAAAAGGTAGGTCTCCATCTTTTTTCAAAGTAGTAGTCTTACCAGAGAATTGAAAAGATCGATAGCAAATGGA
GGCGAGGCATATGAATTTTC

Product: 3-hydroxybutyryl-CoA dehydrogenase

Products: NA

Alternate protein names: Beta-hydroxybutyryl-CoA dehydrogenase; BHBD [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSIQKIVVIGAGQMGSGIAQVCATAGYEVFMQDVKQEQLERGFGVITRNLARQVEKGRMDEETKDATLRRLTTILELDCV
KEADLVIEAAVEKMDIKKKIFANLDEIAPEHTILATNTSSLPITEIAATTNRPEKVIGMHFMNPVPVMKLVEIIRGLATD
DAVYKAIEDITKKIGKVPVEVNDFPGFVSNRILLPMINEAIYALYEGVATKEAIDEVMKLGMNHPMGPLTLADFIGLDTC
LYIMEVLHEGLGDSKYRPCPLLRKYVNAGWLGRKTGRGFYVYE

Sequences:

>Translated_283_residues
MSIQKIVVIGAGQMGSGIAQVCATAGYEVFMQDVKQEQLERGFGVITRNLARQVEKGRMDEETKDATLRRLTTILELDCV
KEADLVIEAAVEKMDIKKKIFANLDEIAPEHTILATNTSSLPITEIAATTNRPEKVIGMHFMNPVPVMKLVEIIRGLATD
DAVYKAIEDITKKIGKVPVEVNDFPGFVSNRILLPMINEAIYALYEGVATKEAIDEVMKLGMNHPMGPLTLADFIGLDTC
LYIMEVLHEGLGDSKYRPCPLLRKYVNAGWLGRKTGRGFYVYE
>Mature_282_residues
SIQKIVVIGAGQMGSGIAQVCATAGYEVFMQDVKQEQLERGFGVITRNLARQVEKGRMDEETKDATLRRLTTILELDCVK
EADLVIEAAVEKMDIKKKIFANLDEIAPEHTILATNTSSLPITEIAATTNRPEKVIGMHFMNPVPVMKLVEIIRGLATDD
AVYKAIEDITKKIGKVPVEVNDFPGFVSNRILLPMINEAIYALYEGVATKEAIDEVMKLGMNHPMGPLTLADFIGLDTCL
YIMEVLHEGLGDSKYRPCPLLRKYVNAGWLGRKTGRGFYVYE

Specific function: Butyrate/butanol-producing pathway. Phenylacetic acid aerobic catabolism. [C]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=289, Percent_Identity=42.560553633218, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI296179427, Length=307, Percent_Identity=41.042345276873, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI20127408, Length=282, Percent_Identity=37.5886524822695, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI261878539, Length=297, Percent_Identity=34.6801346801347, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI68989263, Length=297, Percent_Identity=34.6801346801347, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI115430219, Length=232, Percent_Identity=29.7413793103448, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1787661, Length=283, Percent_Identity=41.696113074205, Blast_Score=230, Evalue=6e-62,
Organism=Escherichia coli, GI1788682, Length=258, Percent_Identity=36.046511627907, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1790281, Length=265, Percent_Identity=34.3396226415094, Blast_Score=157, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17549919, Length=290, Percent_Identity=41.7241379310345, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17553560, Length=288, Percent_Identity=40.625, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17563036, Length=288, Percent_Identity=38.5416666666667, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI25144276, Length=283, Percent_Identity=37.4558303886926, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17508951, Length=283, Percent_Identity=37.4558303886926, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17508953, Length=283, Percent_Identity=37.4558303886926, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17558304, Length=283, Percent_Identity=36.3957597173145, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71985923, Length=285, Percent_Identity=31.9298245614035, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71985930, Length=281, Percent_Identity=30.6049822064057, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI193203623, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533614, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921000, Length=284, Percent_Identity=39.7887323943662, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24583077, Length=284, Percent_Identity=39.7887323943662, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24583079, Length=284, Percent_Identity=39.7887323943662, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI20129993, Length=226, Percent_Identity=27.4336283185841, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI45549573, Length=239, Percent_Identity=27.1966527196653, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022694
- InterPro:   IPR006180
- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N [H]

EC number: =1.1.1.157 [H]

Molecular weight: Translated: 31409; Mature: 31278

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00067 3HCDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQKIVVIGAGQMGSGIAQVCATAGYEVFMQDVKQEQLERGFGVITRNLARQVEKGRMD
CCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EETKDATLRRLTTILELDCVKEADLVIEAAVEKMDIKKKIFANLDEIAPEHTILATNTSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEECCCC
LPITEIAATTNRPEKVIGMHFMNPVPVMKLVEIIRGLATDDAVYKAIEDITKKIGKVPVE
CCHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCE
VNDFPGFVSNRILLPMINEAIYALYEGVATKEAIDEVMKLGMNHPMGPLTLADFIGLDTC
ECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LYIMEVLHEGLGDSKYRPCPLLRKYVNAGWLGRKTGRGFYVYE
HHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SIQKIVVIGAGQMGSGIAQVCATAGYEVFMQDVKQEQLERGFGVITRNLARQVEKGRMD
CCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EETKDATLRRLTTILELDCVKEADLVIEAAVEKMDIKKKIFANLDEIAPEHTILATNTSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEECCCC
LPITEIAATTNRPEKVIGMHFMNPVPVMKLVEIIRGLATDDAVYKAIEDITKKIGKVPVE
CCHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCE
VNDFPGFVSNRILLPMINEAIYALYEGVATKEAIDEVMKLGMNHPMGPLTLADFIGLDTC
ECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LYIMEVLHEGLGDSKYRPCPLLRKYVNAGWLGRKTGRGFYVYE
HHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]