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The map label for this gene is nuoA

Identifier: 152977487

GI number: 152977487

Start: 3879296

End: 3879664

Strand: Reverse

Name: nuoA

Synonym: Bcer98_3819

Alternate gene names: 152977487

Gene position: 3879664-3879296 (Counterclockwise)

Preceding gene: 152977489

Following gene: 152977486

Centisome position: 94.93

GC content: 37.4

Gene sequence:

>369_bases
GTGGAAAATGTATACGAAAATAGTTACATGATTGTTGGTATTTTCTTGCTGCTAGGCATATTACTTCCGGTAGTCGCTCT
GACATTAGGAAAGTTACTACGCCCACATAAACCAAGTGAGGCAAAGAATACAACATATGAAAGTGGGATTGAGCCGTATC
ATGATGCGAATGTTCGCTTTCATGCCCGCTACTACATTTTTGCATTACTATTCGTTATTTTTGATGTAGAAACGTTATTT
TTATATCCGTGGGCAGTGGCATATGACAAGCTTGGGTTGTTTGCATTAATTGAAATGCTCATTTTTGTCGCTATGTTATT
GATAGGATTAGCCTATGCTTGGAAAAAGAAGGTGTTACAATGGCTATAA

Upstream 100 bases:

>100_bases
ATCTAATTATTTAGAAAAATTTAAAAATAATAAAAGAAGAAGATGAAACATACTGTTTACTAAGTGAACTTGTTCTTCAT
TCATGGGGGAGGGTTTCAAA

Downstream 100 bases:

>100_bases
ATTTCGAAGAACTACATCCACAGGAGCAAGCGGAATTAGAAAGGAATATCTTTTTTACAACATTAGAGCAGATAAAAGGA
TGGGCACGTAGCAATTCTTT

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MENVYENSYMIVGIFLLLGILLPVVALTLGKLLRPHKPSEAKNTTYESGIEPYHDANVRFHARYYIFALLFVIFDVETLF
LYPWAVAYDKLGLFALIEMLIFVAMLLIGLAYAWKKKVLQWL

Sequences:

>Translated_122_residues
MENVYENSYMIVGIFLLLGILLPVVALTLGKLLRPHKPSEAKNTTYESGIEPYHDANVRFHARYYIFALLFVIFDVETLF
LYPWAVAYDKLGLFALIEMLIFVAMLLIGLAYAWKKKVLQWL
>Mature_122_residues
MENVYENSYMIVGIFLLLGILLPVVALTLGKLLRPHKPSEAKNTTYESGIEPYHDANVRFHARYYIFALLFVIFDVETLF
LYPWAVAYDKLGLFALIEMLIFVAMLLIGLAYAWKKKVLQWL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=108, Percent_Identity=37.037037037037, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_BACCN (A7GV51)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001377004.1
- STRING:   A7GV51
- EnsemblBacteria:   EBBACT00000036637
- GeneID:   5345984
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_3819
- eggNOG:   COG0838
- GeneTree:   EBGT00050000003148
- HOGENOM:   HBG605540
- OMA:   LLLFDIE
- ProtClustDB:   PRK07756
- BioCyc:   BCER315749:BCER98_3819-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 14133; Mature: 14133

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2270f21c)-; HASH(0x20d70024)-; HASH(0x23cde974)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENVYENSYMIVGIFLLLGILLPVVALTLGKLLRPHKPSEAKNTTYESGIEPYHDANVRF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCHH
HARYYIFALLFVIFDVETLFLYPWAVAYDKLGLFALIEMLIFVAMLLIGLAYAWKKKVLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WL
HH
>Mature Secondary Structure
MENVYENSYMIVGIFLLLGILLPVVALTLGKLLRPHKPSEAKNTTYESGIEPYHDANVRF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCHH
HARYYIFALLFVIFDVETLFLYPWAVAYDKLGLFALIEMLIFVAMLLIGLAYAWKKKVLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WL
HH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA