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The map label for this gene is nuoN [H]

Identifier: 152977477

GI number: 152977477

Start: 3869625

End: 3871145

Strand: Reverse

Name: nuoN [H]

Synonym: Bcer98_3809

Alternate gene names: 152977477

Gene position: 3871145-3869625 (Counterclockwise)

Preceding gene: 152977478

Following gene: 152977476

Centisome position: 94.72

GC content: 38.46

Gene sequence:

>1521_bases
ATGGATATGGAGGTATTGTTTCGGTTACCGTGGCATCTTATGGTTCCGGAGTTTATTCTTCTTGGCGGAGCCATTCTTCT
CTCGCTTCTTGATTTGTTTTTTAAGGTAAATCAAAAGTACGTATCATTTGGAGCCATTCTTACCGCGGGTTTCTCATTTT
TTGCGCTCATTATGCTCTATGATGAACCAGCAGGAGCCATTTTGGACGGTTCCTTCGTATTAGATGGCTTTTCGAAAGGA
TTTAAAACATTACTCTTAGTGGGAGCGCTCCTCGTTTTATGTATCGCGATAAGCGACGATAAAAAAGAGCCGATTCCATA
TAAAGGAGAATATTACTACTTATTTCTCATGGCGATACTTGGTGCGATGTTTATGGCATCTAGCATCGATTTTATTACAC
TCTTTATCAGTTTAGAGCTGCTTTCTCTTTCATCGTATATTTTAGTAGGAATTCGAAAGAAAAGGCGTGCTTCAAATGAG
GCTGCGATGAAATATGTGATTAATGGAGGAATTGCATCAGCTATTACGTTGTTTGGAATGAGTTATGTATATGGTATGAC
AGGATCAACAAATATAGTGGAAATGCAGCGTGTTCTTGCTGGAGGTGTGGCAGGTAGTATTCAACTCTTATTAGCACTTG
CCTTCTTATTAATGTTCGTCGGATTATCATTTAAAATTGCAACGGCACCATTTCATATGTGGGCGCCGGATGTATACGAA
GGGGCACCGACACCAGTAACAGCGTTTCTCGGAACAGTTTCTAAAATTGCTGGATTCATTATGATTGTACGGCTATTCTT
GATGACATTTGCAAGCGTCACAATCCAAGGGAAGGAAGAAACACTGTTTCATTATATGAGTGTCTATATTGCTATTTTAG
CAGGGGTTACGATGATTATTGGTAATGTGATTGCATTAAAGCAACATAATATAAAGAGATTATTTGCTTACTCCGGAATT
GCTCATGCTGGTTATTTACTCGTTCCGCTAGCGGCGCTATCTCCTTTTACAATGGACAGTATGTGGTTTTATATGCTTGC
CTATTTCTTGATGAATGCCGGAGCATTTGCGATTATTCACACATTAATTTTACAAAGTGAGAATGAAAATATAAACATTT
TCTCTGGTTTATACAAACGTTCACCATTTCTAGCGATGATGATGACAATTTTCATTTTATCTTTAGCGGGTATTCCAGGA
ACAGCTGGTTTTATTGGGAAAGTAAATATTTTCTTAGGGGCATTTGTAATAGAGGCGCCTTATTACGTACTTGCATCTGT
AATGATGGGAACAACGGTTATTTCCTATATATATTATTTCCGAATTTTACAGCAGATATTTTTTCGGAAAGGAAATGAAG
GGGACAGAGTGCACATTCCGATAAGTGTAAAAGCTGTCGTTTGCTTCTGCGCATTCGCAACTGTCATGCTCGGAGTTTTA
CCAGCGATTGGCTACAATTTCTTTCATGACTATTTTCCGCTTATGAAGGATTTCTTCTTTACAGGGAACATGGTACAATA
G

Upstream 100 bases:

>100_bases
GTTCTTTTGCTACTTGCATGTATCATAACAATCGGTGTGTTGCCGGATTTATTAGGAGAACCACTTCAAGATACACTAAA
AACATTGGGGGTGAGATAGG

Downstream 100 bases:

>100_bases
TGAAATAAAAAAGTGTAGAGCGATTCCTCTACGCTTTTTATTTGCATGCAAACGCGCACGTAGAAACATGATTTCTCGTT
TTTTGAAGGCTATGGCGCCT

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MDMEVLFRLPWHLMVPEFILLGGAILLSLLDLFFKVNQKYVSFGAILTAGFSFFALIMLYDEPAGAILDGSFVLDGFSKG
FKTLLLVGALLVLCIAISDDKKEPIPYKGEYYYLFLMAILGAMFMASSIDFITLFISLELLSLSSYILVGIRKKRRASNE
AAMKYVINGGIASAITLFGMSYVYGMTGSTNIVEMQRVLAGGVAGSIQLLLALAFLLMFVGLSFKIATAPFHMWAPDVYE
GAPTPVTAFLGTVSKIAGFIMIVRLFLMTFASVTIQGKEETLFHYMSVYIAILAGVTMIIGNVIALKQHNIKRLFAYSGI
AHAGYLLVPLAALSPFTMDSMWFYMLAYFLMNAGAFAIIHTLILQSENENINIFSGLYKRSPFLAMMMTIFILSLAGIPG
TAGFIGKVNIFLGAFVIEAPYYVLASVMMGTTVISYIYYFRILQQIFFRKGNEGDRVHIPISVKAVVCFCAFATVMLGVL
PAIGYNFFHDYFPLMKDFFFTGNMVQ

Sequences:

>Translated_506_residues
MDMEVLFRLPWHLMVPEFILLGGAILLSLLDLFFKVNQKYVSFGAILTAGFSFFALIMLYDEPAGAILDGSFVLDGFSKG
FKTLLLVGALLVLCIAISDDKKEPIPYKGEYYYLFLMAILGAMFMASSIDFITLFISLELLSLSSYILVGIRKKRRASNE
AAMKYVINGGIASAITLFGMSYVYGMTGSTNIVEMQRVLAGGVAGSIQLLLALAFLLMFVGLSFKIATAPFHMWAPDVYE
GAPTPVTAFLGTVSKIAGFIMIVRLFLMTFASVTIQGKEETLFHYMSVYIAILAGVTMIIGNVIALKQHNIKRLFAYSGI
AHAGYLLVPLAALSPFTMDSMWFYMLAYFLMNAGAFAIIHTLILQSENENINIFSGLYKRSPFLAMMMTIFILSLAGIPG
TAGFIGKVNIFLGAFVIEAPYYVLASVMMGTTVISYIYYFRILQQIFFRKGNEGDRVHIPISVKAVVCFCAFATVMLGVL
PAIGYNFFHDYFPLMKDFFFTGNMVQ
>Mature_506_residues
MDMEVLFRLPWHLMVPEFILLGGAILLSLLDLFFKVNQKYVSFGAILTAGFSFFALIMLYDEPAGAILDGSFVLDGFSKG
FKTLLLVGALLVLCIAISDDKKEPIPYKGEYYYLFLMAILGAMFMASSIDFITLFISLELLSLSSYILVGIRKKRRASNE
AAMKYVINGGIASAITLFGMSYVYGMTGSTNIVEMQRVLAGGVAGSIQLLLALAFLLMFVGLSFKIATAPFHMWAPDVYE
GAPTPVTAFLGTVSKIAGFIMIVRLFLMTFASVTIQGKEETLFHYMSVYIAILAGVTMIIGNVIALKQHNIKRLFAYSGI
AHAGYLLVPLAALSPFTMDSMWFYMLAYFLMNAGAFAIIHTLILQSENENINIFSGLYKRSPFLAMMMTIFILSLAGIPG
TAGFIGKVNIFLGAFVIEAPYYVLASVMMGTTVISYIYYFRILQQIFFRKGNEGDRVHIPISVKAVVCFCAFATVMLGVL
PAIGYNFFHDYFPLMKDFFFTGNMVQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=334, Percent_Identity=23.6526946107784, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI145693160, Length=437, Percent_Identity=36.1556064073227, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1788831, Length=310, Percent_Identity=27.0967741935484, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788613, Length=379, Percent_Identity=24.5382585751979, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788614, Length=344, Percent_Identity=27.6162790697674, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788829, Length=385, Percent_Identity=24.4155844155844, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788827, Length=315, Percent_Identity=24.1269841269841, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 55961; Mature: 55961

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMEVLFRLPWHLMVPEFILLGGAILLSLLDLFFKVNQKYVSFGAILTAGFSFFALIMLY
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
DEPAGAILDGSFVLDGFSKGFKTLLLVGALLVLCIAISDDKKEPIPYKGEYYYLFLMAIL
ECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
GAMFMASSIDFITLFISLELLSLSSYILVGIRKKRRASNEAAMKYVINGGIASAITLFGM
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHH
SYVYGMTGSTNIVEMQRVLAGGVAGSIQLLLALAFLLMFVGLSFKIATAPFHMWAPDVYE
HHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHCC
GAPTPVTAFLGTVSKIAGFIMIVRLFLMTFASVTIQGKEETLFHYMSVYIAILAGVTMII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHH
GNVIALKQHNIKRLFAYSGIAHAGYLLVPLAALSPFTMDSMWFYMLAYFLMNAGAFAIIH
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHH
TLILQSENENINIFSGLYKRSPFLAMMMTIFILSLAGIPGTAGFIGKVNIFLGAFVIEAP
HHHHCCCCCCEEHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCH
YYVLASVMMGTTVISYIYYFRILQQIFFRKGNEGDRVHIPISVKAVVCFCAFATVMLGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
PAIGYNFFHDYFPLMKDFFFTGNMVQ
HHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDMEVLFRLPWHLMVPEFILLGGAILLSLLDLFFKVNQKYVSFGAILTAGFSFFALIMLY
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
DEPAGAILDGSFVLDGFSKGFKTLLLVGALLVLCIAISDDKKEPIPYKGEYYYLFLMAIL
ECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
GAMFMASSIDFITLFISLELLSLSSYILVGIRKKRRASNEAAMKYVINGGIASAITLFGM
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHH
SYVYGMTGSTNIVEMQRVLAGGVAGSIQLLLALAFLLMFVGLSFKIATAPFHMWAPDVYE
HHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHCC
GAPTPVTAFLGTVSKIAGFIMIVRLFLMTFASVTIQGKEETLFHYMSVYIAILAGVTMII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHH
GNVIALKQHNIKRLFAYSGIAHAGYLLVPLAALSPFTMDSMWFYMLAYFLMNAGAFAIIH
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHH
TLILQSENENINIFSGLYKRSPFLAMMMTIFILSLAGIPGTAGFIGKVNIFLGAFVIEAP
HHHHCCCCCCEEHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCH
YYVLASVMMGTTVISYIYYFRILQQIFFRKGNEGDRVHIPISVKAVVCFCAFATVMLGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
PAIGYNFFHDYFPLMKDFFFTGNMVQ
HHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]